KR20140093230A - 즉시 방출 4-메틸-3-[[4-(3-피리디닐)-2-피리미디닐]아미노]-n-[5-(4-메틸-1h-이미다졸-1-일)-3-(트리플루오로메틸)페닐] 벤즈아미드 제제 - Google Patents

즉시 방출 4-메틸-3-[[4-(3-피리디닐)-2-피리미디닐]아미노]-n-[5-(4-메틸-1h-이미다졸-1-일)-3-(트리플루오로메틸)페닐] 벤즈아미드 제제 Download PDF

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Publication number
KR20140093230A
KR20140093230A KR1020147012521A KR20147012521A KR20140093230A KR 20140093230 A KR20140093230 A KR 20140093230A KR 1020147012521 A KR1020147012521 A KR 1020147012521A KR 20147012521 A KR20147012521 A KR 20147012521A KR 20140093230 A KR20140093230 A KR 20140093230A
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KR
South Korea
Prior art keywords
methyl
dosage form
solid dosage
phenyl
pyrimidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020147012521A
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English (en)
Korean (ko)
Inventor
업카르 바르드와즈
만게시 사다시브 보르다웨카르
안 리세 컴포트
핑 리
소우펭 리
알렉세이 마카로브
Original Assignee
노파르티스 아게
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Publication of KR20140093230A publication Critical patent/KR20140093230A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020147012521A 2011-11-14 2012-11-12 즉시 방출 4-메틸-3-[[4-(3-피리디닐)-2-피리미디닐]아미노]-n-[5-(4-메틸-1h-이미다졸-1-일)-3-(트리플루오로메틸)페닐] 벤즈아미드 제제 Ceased KR20140093230A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161559281P 2011-11-14 2011-11-14
US61/559,281 2011-11-14
PCT/US2012/064610 WO2013074432A1 (en) 2011-11-14 2012-11-12 Immediate release 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-[5-(4-methyl- 1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide formulation

Publications (1)

Publication Number Publication Date
KR20140093230A true KR20140093230A (ko) 2014-07-25

Family

ID=47324402

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147012521A Ceased KR20140093230A (ko) 2011-11-14 2012-11-12 즉시 방출 4-메틸-3-[[4-(3-피리디닐)-2-피리미디닐]아미노]-n-[5-(4-메틸-1h-이미다졸-1-일)-3-(트리플루오로메틸)페닐] 벤즈아미드 제제

Country Status (23)

Country Link
EP (1) EP2779995A1 (enExample)
JP (1) JP6275645B2 (enExample)
KR (1) KR20140093230A (enExample)
CN (1) CN103930094A (enExample)
AR (1) AR088844A1 (enExample)
BR (1) BR112014011518A2 (enExample)
CA (1) CA2855503A1 (enExample)
CL (1) CL2014001247A1 (enExample)
CO (1) CO6960546A2 (enExample)
EA (1) EA201490960A1 (enExample)
GT (1) GT201400094A (enExample)
HK (1) HK1197025A1 (enExample)
IL (1) IL232480A0 (enExample)
IN (1) IN2014DN03416A (enExample)
MA (1) MA35636B1 (enExample)
MX (1) MX2014005874A (enExample)
PE (1) PE20141337A1 (enExample)
PH (1) PH12014501062B1 (enExample)
SG (2) SG10201707768RA (enExample)
TN (1) TN2014000177A1 (enExample)
TW (1) TWI574690B (enExample)
WO (1) WO2013074432A1 (enExample)
ZA (1) ZA201402756B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2792360A1 (en) 2013-04-18 2014-10-22 IP Gesellschaft für Management mbH (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV
CZ2017821A3 (cs) 2017-12-20 2019-07-03 Zentiva, K.S. Léková forma obsahující krystalický nilotinib
JP7378279B2 (ja) * 2019-11-18 2023-11-13 日本化薬株式会社 ニロチニブを有効成分とする医薬錠剤及びその製造方法
JP7489849B2 (ja) * 2020-07-20 2024-05-24 日本化薬株式会社 ニロチニブ錠剤
JP7776274B2 (ja) * 2021-07-19 2025-11-26 日本化薬株式会社 ニロチニブ錠剤およびその製造方法
JP7776275B2 (ja) * 2021-07-26 2025-11-26 日本化薬株式会社 ニロチニブ錠剤およびその製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0215676D0 (en) * 2002-07-05 2002-08-14 Novartis Ag Organic compounds
GT200600316A (es) 2005-07-20 2007-04-02 Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida.
GT200600315A (es) 2005-07-20 2007-03-19 Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida
EP1923053A1 (en) * 2006-09-27 2008-05-21 Novartis AG Pharmaceutical compositions comprising nilotinib or its salt
US20100136097A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for modulating inflammation
IN2011CH01887A (enExample) * 2011-06-02 2012-12-14

Also Published As

Publication number Publication date
EA201490960A1 (ru) 2014-08-29
GT201400094A (es) 2017-09-28
CN103930094A (zh) 2014-07-16
CA2855503A1 (en) 2013-05-23
MA35636B1 (fr) 2014-11-01
CO6960546A2 (es) 2014-05-30
JP6275645B2 (ja) 2018-02-07
PH12014501062A1 (en) 2014-06-23
CL2014001247A1 (es) 2014-10-17
EP2779995A1 (en) 2014-09-24
IN2014DN03416A (enExample) 2015-06-26
AU2012339829A1 (en) 2014-05-29
SG10201707768RA (en) 2017-10-30
IL232480A0 (en) 2014-06-30
PE20141337A1 (es) 2014-10-16
WO2013074432A1 (en) 2013-05-23
BR112014011518A2 (pt) 2017-05-16
TW201325594A (zh) 2013-07-01
PH12014501062B1 (en) 2018-04-20
AU2012339829B2 (en) 2016-05-12
SG11201401476TA (en) 2014-10-30
HK1197025A1 (en) 2015-01-02
ZA201402756B (en) 2015-04-29
NZ623844A (en) 2016-09-30
AR088844A1 (es) 2014-07-10
TWI574690B (zh) 2017-03-21
JP2014533283A (ja) 2014-12-11
MX2014005874A (es) 2014-06-23
TN2014000177A1 (en) 2015-09-30

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