KR20140030153A - 항-인테그린을 사용하여 항혈관 형성 요법을 개선하기 위한 방법 및 조성물 - Google Patents
항-인테그린을 사용하여 항혈관 형성 요법을 개선하기 위한 방법 및 조성물 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| PCT/US2012/030204 WO2012129448A1 (en) | 2011-03-23 | 2012-03-22 | Methods and compositions for improving antiangiogenic therapy with anti-integrins |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2020145669A1 (ko) * | 2019-01-10 | 2020-07-16 | 에스지메디칼 주식회사 | 항 베타 1 인테그린 인간화 항체 및 이를 포함하는 암치료용 약학 조성물 |
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| JP2014523398A (ja) * | 2011-03-23 | 2014-09-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 抗−インテグリンを用いた抗血管新生療法を改良するための方法及び組成物 |
| WO2014105910A1 (en) | 2012-12-26 | 2014-07-03 | Oncosynergy, Inc. | ANTI- INTEGRIN β1 ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF |
| EP3067698A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Pd-ecgf as biomarker of cancer |
| EP3067369A1 (en) | 2015-03-11 | 2016-09-14 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Methods and compositions for the treatment of anti-angiogenic resistant cancer |
| AU2016311298A1 (en) | 2015-08-25 | 2018-02-08 | Histide Ag | Compounds for inducing tissue formation and uses thereof |
| AU2016323408A1 (en) * | 2015-09-17 | 2018-04-19 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
| WO2017046229A1 (en) * | 2015-09-17 | 2017-03-23 | Histide Ag | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
| EP3906932A3 (en) * | 2015-09-17 | 2021-12-01 | Histide AG | Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof |
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| US5846536A (en) * | 1996-10-04 | 1998-12-08 | The Regents Of The University Of California | Restoration of normal phenotype in cancer cells |
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| WO2009018226A2 (en) * | 2007-07-27 | 2009-02-05 | Facet Biotech Corporation | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (cd49e) |
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| JP2014523398A (ja) * | 2011-03-23 | 2014-09-11 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 抗−インテグリンを用いた抗血管新生療法を改良するための方法及び組成物 |
| WO2014105910A1 (en) * | 2012-12-26 | 2014-07-03 | Oncosynergy, Inc. | ANTI- INTEGRIN β1 ANTIBODY COMPOSITIONS AND METHODS OF USE THEREOF |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020145669A1 (ko) * | 2019-01-10 | 2020-07-16 | 에스지메디칼 주식회사 | 항 베타 1 인테그린 인간화 항체 및 이를 포함하는 암치료용 약학 조성물 |
| US12319732B2 (en) | 2019-01-10 | 2025-06-03 | Sg Medical Inc. | Anti-beta 1 integrin humanized antibody, and pharmaceutical composition for treating cancer, comprising same |
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| EP2688585B1 (en) | 2018-09-05 |
| US11185585B2 (en) | 2021-11-30 |
| CA2830908C (en) | 2019-09-24 |
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| WO2012129448A1 (en) | 2012-09-27 |
| JP2014523398A (ja) | 2014-09-11 |
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| EP2688585A1 (en) | 2014-01-29 |
| AU2012230809A1 (en) | 2013-10-10 |
| US20180236073A1 (en) | 2018-08-23 |
| EP2688585A4 (en) | 2015-05-06 |
| US20140079637A1 (en) | 2014-03-20 |
| US20220111045A1 (en) | 2022-04-14 |
| CA2830908A1 (en) | 2012-09-27 |
| AU2012230809B2 (en) | 2017-06-29 |
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