KR20140024247A - 생체분자 특징을 평가하기 위한 시스템 및 방법 - Google Patents

생체분자 특징을 평가하기 위한 시스템 및 방법 Download PDF

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Publication number
KR20140024247A
KR20140024247A KR1020137012549A KR20137012549A KR20140024247A KR 20140024247 A KR20140024247 A KR 20140024247A KR 1020137012549 A KR1020137012549 A KR 1020137012549A KR 20137012549 A KR20137012549 A KR 20137012549A KR 20140024247 A KR20140024247 A KR 20140024247A
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South Korea
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polynucleotide
label
sample
illumination
site
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KR1020137012549A
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English (en)
Korean (ko)
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패릭쉿 에이. 데쉬팬드
아써 쥐. 마린
마이클 코처스퍼거
알렉시 쉐로노브
윌리엄 스테드맨
밍 시아오
헨리 비. 사도브스키
소메스쿠마 다스
매튜 애커나
대니얼 보지노브
마이클 레쿠아
한 카오
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바이오나노 제노믹스, 인크.
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Publication of KR20140024247A publication Critical patent/KR20140024247A/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
KR1020137012549A 2010-10-20 2011-10-20 생체분자 특징을 평가하기 위한 시스템 및 방법 KR20140024247A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US39491510P 2010-10-20 2010-10-20
US61/394,915 2010-10-20
US40730210P 2010-10-27 2010-10-27
US40718210P 2010-10-27 2010-10-27
US61/407,302 2010-10-27
US61/407,182 2010-10-27
US41851610P 2010-12-01 2010-12-01
US61/418,516 2010-12-01
PCT/US2011/057115 WO2012054735A2 (fr) 2010-10-20 2011-10-20 Systèmes et procédés pour évaluer des caractéristiques de biomolécules

Publications (1)

Publication Number Publication Date
KR20140024247A true KR20140024247A (ko) 2014-02-28

Family

ID=44903427

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020137012549A KR20140024247A (ko) 2010-10-20 2011-10-20 생체분자 특징을 평가하기 위한 시스템 및 방법

Country Status (10)

Country Link
US (1) US20140030705A1 (fr)
EP (1) EP2630258A2 (fr)
JP (1) JP2013542730A (fr)
KR (1) KR20140024247A (fr)
CN (2) CN103443290B (fr)
AU (1) AU2011316989B2 (fr)
CA (1) CA2815359A1 (fr)
RU (1) RU2013117936A (fr)
SG (2) SG10201508373UA (fr)
WO (1) WO2012054735A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190093197A (ko) * 2016-12-09 2019-08-08 얼티뷰, 인크. 표지된 핵산 조영제를 사용한 다중 이미지형성을 위한 개선된 방법
KR20200008628A (ko) * 2018-01-05 2020-01-28 일루미나, 인코포레이티드 시퀀싱 시스템에서의 시약 냉각기 불안정성 및 플로우 셀 히터 고장의 예측

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AU2007338862B2 (en) 2006-07-19 2014-02-06 Bionano Genomics, Inc. Nanonozzle device arrays: their preparation and use for macromolecular analysis
EP2136922B1 (fr) 2007-03-28 2012-12-05 BioNano Genomics, Inc. Procédés d'analyse macromoléculaire utilisant des réseaux de nanocanaux
CA2729159C (fr) 2008-06-30 2020-01-14 Bionanomatrix, Inc. Procedes et dispositif pour analyse mono-moleculaire de genome entier
EP2370594B1 (fr) 2008-11-18 2014-01-08 BioNano Genomics, Inc. Cartographie et séquences de polynucléotide
WO2015130696A1 (fr) 2014-02-25 2015-09-03 Bionano Genomics, Inc. Réduction du biais dans des mesures de couverture génomique
US10844424B2 (en) 2013-02-20 2020-11-24 Bionano Genomics, Inc. Reduction of bias in genomic coverage measurements
WO2014130589A1 (fr) 2013-02-20 2014-08-28 Bionano Genomics, Inc. Caractérisation de molécules en nanofluidique
WO2015134785A1 (fr) * 2014-03-07 2015-09-11 Bionano Genomics, Inc. Traitement de polynucléotides
US20160017316A1 (en) * 2014-07-18 2016-01-21 Bionano Genomics, Inc. Isolation of megabase-sized dna from plant and animal tissues
WO2016069539A1 (fr) * 2014-10-27 2016-05-06 Helix Nanotechnologies, Inc. Systèmes et procédés de criblage à l'aide d'un enregistreur de molécules
EP3307755A4 (fr) 2015-05-12 2018-12-26 Wake Forest University Health Sciences Identification de modifications génétiques
USD815145S1 (en) * 2016-03-25 2018-04-10 Illumina, Inc. Display screen with application icon
USD815146S1 (en) 2016-03-25 2018-04-10 Illimina, Inc. Display screen with application icon
CN106282159A (zh) * 2016-08-03 2017-01-04 刘鹏飞 利用射线实现供二代测序使用的dna片段化的方法及装置
CN108265112B (zh) * 2016-12-30 2023-04-25 深圳市真迈生物科技有限公司 对序列测定反应进行控制的方法、序列测定系统和控制装置
KR20180078596A (ko) 2016-12-30 2018-07-10 삼성전자주식회사 Af 방법 및 이를 수행하는 전자 장치
CA3214282A1 (fr) 2021-03-29 2022-10-06 Illumina, Inc. Compositions et procedes pour evaluer l'endommagement de l'adn dans une bibliotheque et normaliser une polarisation de taille d'amplicon

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EP0851939A4 (fr) * 1995-08-30 2001-02-28 New York Medical College Methodes de marquage des extremites d'adn par des nucleotides halogenes et de detection de ceux-ci a l'aide d'anticorps
US20010055764A1 (en) * 1999-05-07 2001-12-27 Empedocles Stephen A. Microarray methods utilizing semiconductor nanocrystals
US6927065B2 (en) * 1999-08-13 2005-08-09 U.S. Genomics, Inc. Methods and apparatus for characterization of single polymers
JP2004514160A (ja) 2000-10-06 2004-05-13 ハイワイアード・テクノロジーズ・インコーポレーテッド ミキシングメディアメッセージングシステムのための方法及び装置
CN1627120A (zh) * 2003-12-12 2005-06-15 上海爱建纳米科技发展有限公司 纳米颗粒显微镜
CN2758750Y (zh) * 2003-12-12 2006-02-15 上海爱建纳米科技发展有限公司 原子力颗粒显微镜
US20050208538A1 (en) * 2003-12-29 2005-09-22 Nurith Kurn Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids
KR100597870B1 (ko) * 2004-04-01 2006-07-06 한국과학기술원 고속 스크리닝 또는 고속 분석을 위한 미소 유체 칩
EP1774034A2 (fr) * 2004-06-07 2007-04-18 The California Institute of Technology Detection des mesappariements d'adn et des lesions oxydantes
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CA2729159C (fr) * 2008-06-30 2020-01-14 Bionanomatrix, Inc. Procedes et dispositif pour analyse mono-moleculaire de genome entier
KR20100024533A (ko) 2008-08-26 2010-03-08 삼성전자주식회사 표시 기판의 제조 방법, 이를 포함하는 표시 장치의 제조 방법 및 표시 기판
ES2408185T3 (es) 2008-08-26 2013-06-18 Federal-Mogul S.A. Dispositivo de limpiaparabrisas
US8835110B2 (en) * 2008-11-04 2014-09-16 The Johns Hopkins University DNA integrity assay (DIA) for cancer diagnostics, using confocal fluorescence spectroscopy
EP2370594B1 (fr) * 2008-11-18 2014-01-08 BioNano Genomics, Inc. Cartographie et séquences de polynucléotide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190093197A (ko) * 2016-12-09 2019-08-08 얼티뷰, 인크. 표지된 핵산 조영제를 사용한 다중 이미지형성을 위한 개선된 방법
KR20200008628A (ko) * 2018-01-05 2020-01-28 일루미나, 인코포레이티드 시퀀싱 시스템에서의 시약 냉각기 불안정성 및 플로우 셀 히터 고장의 예측

Also Published As

Publication number Publication date
CN103443290A (zh) 2013-12-11
CA2815359A1 (fr) 2012-04-26
AU2011316989A1 (en) 2013-05-02
AU2011316989B2 (en) 2016-06-16
US20140030705A1 (en) 2014-01-30
SG189366A1 (en) 2013-05-31
CN103443290B (zh) 2016-06-08
SG10201508373UA (en) 2015-11-27
WO2012054735A2 (fr) 2012-04-26
EP2630258A2 (fr) 2013-08-28
CN106048000A (zh) 2016-10-26
CN106048000B (zh) 2020-05-01
RU2013117936A (ru) 2014-11-27
WO2012054735A3 (fr) 2012-11-01
JP2013542730A (ja) 2013-11-28

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