KR20130134505A - Composition for treating scalp and hair, method and device for making the same - Google Patents
Composition for treating scalp and hair, method and device for making the same Download PDFInfo
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- KR20130134505A KR20130134505A KR1020120058063A KR20120058063A KR20130134505A KR 20130134505 A KR20130134505 A KR 20130134505A KR 1020120058063 A KR1020120058063 A KR 1020120058063A KR 20120058063 A KR20120058063 A KR 20120058063A KR 20130134505 A KR20130134505 A KR 20130134505A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
- A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/002—Preparations for repairing the hair, e.g. hair cure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
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Abstract
Description
The present invention relates to a composition for improving the scalp and hair, a method for manufacturing the same, and a manufacturing apparatus. More specifically, seaweeds are used as raw materials, and rice bran is used as a subsidiary material, but supercritical or subcritical liquefied carbon dioxide is used as the main solvent, and functional materials including natural pigment components are extracted, and the extracted substances are mixed in a single phase. Effectiveness and stability of functional substances containing strong natural fragrances or pigments and essential oils, soothing and irritating scalp irritation and inflammation, as well as conditioning to restore rough and damaged hair to make hair soft and smooth It can improve the problem scalp such as psoriasis, seborrhea and erythema by minimizing the skin irritation, and use the separation tank to secure high homogeneity and simplify the whole process without any additional mixing process. In the separation tank, a co-solvent containing carbon dioxide For it to re-use the recovered carbon dioxide as the main solvent and the scalp hair and improved composition that relates to a production method and production apparatus.
Recently, due to the change in diet, the increase of stress caused by the social environment, the number of people suffering from abnormal symptoms of the scalp and hair is increasing, and the age is also decreasing. In addition, the hair loss population of women is also increasing. Accordingly, research has been conducted on compositions capable of preventing abnormal symptoms of various scalp and hair, including hair loss, and improving the condition of the scalp and hair.
Existing scalp and hair-related products are most often the main ingredient to the effect of chemicals, there is a problem that causes side effects such as irritating the scalp in the long-term use.
Meanwhile, human skin undergoes various physical and chemical changes during the aging process. Aging can be caused by UV, stress, disease conditions, environmental factors, wounds, and the activation of free radicals with age. If this condition is exacerbated, it destroys the antioxidant defenses in vivo and damages cells and tissues, promoting adult disease and aging.
Therefore, cell membranes are protected by eliminating free radicals, which are mediated by metabolic processes in the body, or by irradiating with ultraviolet rays or inflammatory reactions. Can become healthy skin.
Aging involves not only free radicals, but also an enzyme called matrix metalloprotease (MMP) .In vivo, the synthesis and degradation of cell substrates such as collagen is properly regulated, but the synthesis decreases as aging progresses. Expression of matrix metalloproteinase, an enzyme that degrades collagen, is promoted, resulting in decreased skin elasticity and wrinkles. In addition, such enzymes may be activated by ultraviolet irradiation.
Therefore, there is a need for development of a substance capable of regulating MMP expression in which activation is induced in cells or inhibiting its activity. Until now, most of the raw materials used as cosmetic materials simply inhibit enzyme activity.
Recently, many cosmetic products using natural products have been developed to reduce skin irritation caused by such chemicals. Conventional natural-derived functional oil-containing cosmetics are often prepared by simply mixing functional oils with conventional cosmetic base ingredients in one container. In this case, it is difficult to precisely adjust the temperature change of the manufacturing process, there is a problem that the fragrance components of the functional oil is volatilized, or the active ingredient of the oil is destroyed. In addition, the physical properties of the functional oil sensitive to external environmental conditions are not optimized, the stability of the functional oil is reduced, there is a problem that can not be mixed homogeneously with the cosmetic base components or discolored, deteriorated and deodorized effective activity is lowered.
Therefore, there is a need for development of a composition for improving problem scalp (psoriasis, seborrhea, erythema, etc.) that uses natural products to alleviate scalp irritation and inflammation caused by various hair and scalp and hair abnormalities.
The present invention has been made to solve the above problems, in particular, using natural products, but to ensure the effectiveness and stability of the natural product-derived functional oil, relieve scalp irritation and inflammation, exhibit a soothing effect, rough and It is an object of the present invention to provide a composition for improving the scalp and hair, a method for producing the same, and a manufacturing apparatus, which provide a conditioning effect of repairing damaged hair to make the hair soft and smooth.
The scalp and hair improvement composition according to the present invention devised to achieve the above object is extracted with a supercritical or subcritical liquefied carbon dioxide as the main solvent, algae or its processed products or by-products, shellfish or its processed products or by-products, vegetables or Contains any one or two or more selected from the processed products or by-products as raw materials, and selected from rice bran or processed products or by-products, wheat germ or processed products or by-products, rice bran or processed products or by-products, bran or processed products or by-products Or a mixture of two or more as a submaterial.
In addition, the co-solvent mixed in the main solvent may be any one or a mixture of two or more selected from the group consisting of water, ethanol, methanol, propanol, ethyl acetate, acetone and nucleic acid.
Method for producing a composition for improving the scalp and hair according to the present invention is (a) preparing seaweed or its processed products or by-products, crustaceans or processed products or by-products, vegetables or mixtures of those processed products or by-products as raw materials step; (b) preparing as a subsidiary material a mixture of rice bran or its products or by-products, wheat germ or its products or by-products, rice bran or its products or by-products, bran or its products or by-products; (c) mixing the raw materials and the submaterial; (d) Supercritical or subcritical liquefied carbon dioxide as the main solvent, water, ethanol, methanol, propanol, ethyl acetate, acetone and nucleic acid as a co-solvent, any one or two or more mixtures selected from the group consisting of co-solvent Extracting a mixture of the raw materials and the subsidiary materials by heating and pressing with an extraction solvent mixed with a solvent; And (e) characterized in that it comprises a step of separating the co-solvent containing the extract and the carbon dioxide containing the extract containing the raw material and the subsidiary ingredient components while the pressure state of step (d) is released.
In addition, the carbon dioxide recovered through the co-solvent containing the carbon dioxide separated in step (e) may be re-used as the main solvent.
The apparatus for producing a scalp and hair improvement composition according to the present invention includes a main solvent tank containing supercritical or subcritical liquefied carbon dioxide; A co-solvent tank containing any one or two or more mixtures selected from the group consisting of water, ethanol, methanol, propanol, ethyl acetate, acetone and nucleic acid; An extractor connected to the main solvent tank and the co-solvent tank, respectively, to receive a mixture of raw materials including kelp and subsidiary materials including rice bran; And a separator connected to the extraction tank and separating the extract including the raw material and the subsidiary ingredient component into a co-solvent containing carbon dioxide, and recovered through the co-solvent containing the carbon dioxide in the separation tank. The carbon dioxide is supplied to the main solvent tank.
According to the present invention, seaweeds are used as raw materials, and rice bran is used as a subsidiary material, but supercritical or subcritical liquefied carbon dioxide is extracted as a main solvent to extract functional substances including natural pigment components, and the extracted substances are mixed in a single phase. By securing the effectiveness and stability of functional substances, including highly volatile natural fragrances or pigments and essential oils, it relieves scalp irritation and inflammation and has a soothing effect, as well as repairs rough and damaged hair to make hair soft and smooth By providing a conditioning effect to improve the problem scalp, such as psoriasis, seborrhea, erythema, it has the effect of minimizing skin irritation.
In addition, according to the present invention using a separation tank to ensure a high homogeneity of the functional material as a mixture without a separate mixing process and simplify the overall process, the carbon dioxide recovered through the co-solvent containing carbon dioxide in the separation tank as the main solvent It can be reused.
1 is a flowchart of a method for preparing a composition for improving scalp and hair according to a preferred embodiment of the present invention;
2 is a block diagram of a composition for producing a composition for improving the scalp and hair according to a preferred embodiment of the present invention.
Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the drawings, the same reference numerals are used to designate the same or similar components throughout the drawings. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear. In addition, the preferred embodiments of the present invention will be described below, but it is needless to say that the technical idea of the present invention is not limited thereto and can be variously modified by those skilled in the art.
1 is a flow chart of a method for producing a composition for improving the scalp and hair according to a preferred embodiment of the present invention. 2 is a block diagram of a composition for producing a composition for improving the scalp and hair according to a preferred embodiment of the present invention.
Method for producing a composition for improving the scalp and hair according to a preferred embodiment of the present invention, referring to Figure 1, material preparation step (S10), material mixing step (S20), solvent mixing step (S30), extraction step (S40) ), And a separation step (S50).
Step S10 is a step of preparing a material containing a functional material such as a natural pigment component, a natural fragrance component to be extracted, step S20 is a step of mixing the prepared raw materials and subsidiary materials.
It is also possible to use any one selected from various seaweeds, crustaceans, or vegetables as raw materials, or mix the heterogeneous raw materials in any ratio. When mixing the raw materials, it is preferable to configure the mixing ratio within the range of 1 to 99% by weight.
Raw materials are not limited to seaweeds, shellfish and vegetables themselves, and may include processed products and by-products. The form of the raw material includes the case of powder or liquid, and in the case of powder or liquid, processed products such as juice or extract that are already processed and sold are possible.
That is, the raw material may be any one or a mixture of seaweeds or processed products or by-products, crustaceans or processed products or by-products, vegetables or processed products or by-products.
A variety of grains may be used as the subsidiary material, in particular, rice bran or wheat germ, or processed products or by-products thereof may be used. The subsidiary materials may be neatly trimmed and then cut into a predetermined size. Meanwhile, rice bran or bran may be used instead of rice bran or wheat germ, and a mixture thereof may be used.
That is, as a subsidiary material, rice bran or its processed products or by-products, wheat germ or its processed products or by-products, rice bran or its processed products or by-products, bran or its processed products or by-products may be used.
Subsidiary materials contain substances that collect and adsorb functional materials from the raw materials in the extraction step. When extracting a functional material from only the raw material, due to the nature of the extract to be extracted from the raw material, the lipid content is insufficient to capture the fat-soluble pigment, there is a problem that the yield (yield) significantly decreases over time. Therefore, by mixing the subsidiary materials with the raw materials, such functional materials can be easily collected.
In addition, when using rice bran or wheat germ as a subsidiary material, polyunsaturated fatty acids (HUFA), vitamin B1, tocopherol, sterol, protein, minerals, fiber, a-tocopherol, r- Highly functional substances such as oryzanol and essential amino acids can be extracted and mixed with raw materials to produce more effective functional substances.
The prepared raw materials and subsidiary materials may be evenly mixed in a predetermined ratio, but may be mixed in a relative mixing ratio within a range of 1 to 99% by weight, such as 1: 1 or 7: 3 or 3: 7, respectively.
Step S30 is a step of mixing the main solvent and the cosolvent.
Supercritical or subcritical liquefied carbon dioxide is used as the main solvent, and any one or a mixture of two or more selected from the group consisting of water, ethanol, methanol, propanol, ethyl acetate, acetone, and nucleic acid may be used.
Supercritical or subcritical carbon dioxide, which is the main solvent, has a nonpolar characteristic, and thus extracts functional substances such as non-polar natural pigment components contained in raw materials and subsidiary materials, and mixes the extracted substances into a single phase to increase the volatility. Functional substances, including strong natural fragrances or pigments and essential oils, can be maintained in a stable state.
Step S40 is a step of extracting a mixture of raw materials and subsidiary materials by heating and pressurizing with an extraction solvent mixed with a main solvent and a cosolvent. That is, step S40 is a step of extracting a functional material from the mixed material using an extraction solvent, in order to obtain a higher purity extract using supercritical carbon dioxide extraction, organic solvent extraction method using a common heating and concentration method, hot water extraction method, Neutral salt extraction method is also possible.
As shown in FIG. 2, in order to obtain high solubility and high extraction efficiency, pressure is rapidly reduced in the
In the step S40, the flow rate of the main solvent is 100 to 300 g / min, and the flow rate of the cosolvent is 1 to 3 mL / min, so that the main solvent and the cosolvent are continuously introduced into the extraction tank. At this time, the mixing of the co-solvent may be performed in advance before the extraction step (S40), or may be configured by adjusting the discharge amount of the pipe supplied as shown in FIG.
The extraction conditions are preferably 30 to 60 degrees Celsius and a pressure of 80 to 500 bar.
A mixed extract was prepared using kelp as a raw material and wheat germ as an auxiliary material, and free radical scavenging ability was measured by DPPH (2,2-Diphenyl-1-picrylhydrazyl) method. The results are summarized in Table 1 below.
Referring to Table 1, it can be seen that free radical scavenging ability increases as the extraction temperature increases. In the case of pressure, the free radical scavenging ability increases as the pressure increases to 200 bar, but decreases slightly at 250 bar, and then shows the maximum value at 300 bar.
The step S50 is a step of separating the co-solvent containing the extract and the carbon dioxide-containing co-solvent while the pressure of the step S40 is released. At this time, the carbon dioxide recovered through the co-solvent containing carbon dioxide separated through the step S50 is preferably reused as the main solvent.
Referring to Figure 2, the apparatus for producing a scalp and hair improvement composition according to a preferred embodiment of the present invention is a
The
The main
One side of the
Cereals, including rice bran, which are used as subsidiary materials, are refined in extraction tanks to produce chemically stable and excellent capturing rice bran oil, wheat germ oil, and other functional substances including functional pigments extracted from seaweeds, shellfish, and vegetables used as raw materials. It acts as a collector or adsorbent to prevent loss.
The lower end of the
When the extraction occurs in the
As the
The functional material is not composed of a single material alone, but a mixture of materials. In general, such a mixture should be stirred using a homogenizer for homogeneous mixing.
However, the apparatus for preparing a composition for improving the scalp and hair according to the preferred embodiment of the present invention can use a separator having a spray nozzle in a separation step, thereby ensuring high homogeneity of the functional material as a mixture without a separate mixing process.
The scalp and hair improvement composition according to a preferred embodiment of the present invention may be applied to have a formulation of a shampoo, tonic, treatment, ampoule or scalp pack.
Hereinafter, an example of preparing a composition for improving the scalp and hair using kelp and wheat embryos, and describing an example of preparing a shampoo using the same, is described.
The kelp powder as the main raw material and the wheat germ powder as the subsidiary material are charged to the extraction tower, the main solvent is supercritical liquid carbon dioxide (107.16 g / min), the cosolvent is co-solvent (ethanol) (2 mL / min), As extraction conditions, the temperature was 32 ° C., the pressure was 300 bar, and the extraction time was set to 120 min to prepare a composition for improving scalp and hair. And, using such a composition to prepare a shampoo as shown in Table 2 and Table 3 below.
Kelp was used as a raw material, wheat germ was used as a subsidiary material, and a composition for improving damaged hair was prepared by using supercritical carbon dioxide extraction, and then prescribed as a hair pack, hair oil, and hair essence formulation.
Table 4 summarizes the results of the cytotoxicity test using the scalp and hair improvement composition according to the present invention.
The MTT assay showed absorbance in proportion to the number of living cells, but the results of Table 4 show no tendency to be significantly inhibited. Therefore, the toxicity test showed no toxicity.
Table 5 and Table 6 are the results of the evaluation of hair extension rate, hair tensile strength, hair thickness improvement by preparing a hair improvement composition according to a preferred embodiment of the present invention in a scalp tonic formulation.
Table 5 summarizes the results of
Clinical hairs in the organic solvent extract-containing prototypes (A, B, C) showed a relatively good effect in terms of tensile strength, but the rate of improvement of elongation tends to decrease, which is not desirable for damaged hair.
On the other hand, the clinical hair in the supercritical extract-containing prototype group (D, E, F) showed excellent effects in both tensile strength and elongation rate improvement, and is considered to be suitable as a damaged hair improvement product group.
Table 6 is a photograph of the surface damage degree of the 0 ~ 2 weeks results.
The overall clinical results of post-clinical hair surface damage of the proto-group containing organic solvent and supercritical carbon dioxide extract showed that A-F hair was much more damaged than pre-clinical hair. The state returned to hair was shown.
It will be apparent to those skilled in the art that various modifications, substitutions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims. will be. Accordingly, the embodiments disclosed in the present invention and the accompanying drawings are not intended to limit the technical spirit of the present invention but to describe the present invention, and the scope of the technical idea of the present invention is not limited by the embodiments and the accompanying drawings. . The protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the equivalent scope should be interpreted as being included in the scope of the present invention.
10-co-solvent tank 20-main solvent tank
30-Extraction tank 40-Separation tank
50-Extract Recovery Tank 60-Co-Solvent Recovery Tank
Claims (5)
The co-solvent mixed in the main solvent is water, ethanol, methanol, propanol, ethyl acetate, acetone and a nucleic acid composition for improving the scalp and hair, characterized in that at least two or more mixtures selected from the group consisting of.
(b) preparing as a subsidiary material a mixture of rice bran or its products or by-products, wheat germ or its products or by-products, rice bran or its products or by-products, bran or its products or by-products;
(c) mixing the raw materials and the submaterial;
(d) Supercritical or subcritical liquefied carbon dioxide as the main solvent, water, ethanol, methanol, propanol, ethyl acetate, acetone and nucleic acid as a co-solvent, any one or two or more mixtures selected from the group consisting of co-solvent Extracting a mixture of the raw materials and the subsidiary materials by heating and pressing with an extraction solvent mixed with a solvent; And
(e) separating the extract containing the raw materials and the subsidiary ingredients and the co-solvent containing carbon dioxide while the pressurized state of step (d) is released;
Method for producing a scalp and hair improvement composition comprising a.
Method of producing a composition for improving the scalp and hair, characterized in that to reuse the carbon dioxide recovered through the co-solvent containing the carbon dioxide separated in the step (e) as the main solvent.
A co-solvent tank containing any one or two or more mixtures selected from the group consisting of water, ethanol, methanol, propanol, ethyl acetate, acetone and nucleic acid;
An extractor connected to the main solvent tank and the co-solvent tank, respectively, to receive a mixture of raw materials including kelp and subsidiary materials including rice bran; And
A separator connected to the extraction tank and separating the extract including the raw material and the subsidiary ingredient component into a co-solvent containing carbon dioxide.
Including;
Apparatus for producing a composition for improving the scalp and hair, characterized in that the carbon dioxide recovered through the co-solvent containing the carbon dioxide in the separation tank is supplied to the main solvent tank.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160146086A (en) * | 2015-06-11 | 2016-12-21 | 주식회사 에코마인 | Off-flavor Reducing Method for Seaweed Using Organic Acid Hydrolysis and Supercritical Solvent Drying |
KR102417864B1 (en) | 2022-04-04 | 2022-07-06 | (주)뉴겐코스메틱 | Haircare cosmetic materials for improving condition ofdamagedhair, Manufacturing method thereof and Hair-care products |
-
2012
- 2012-05-31 KR KR1020120058063A patent/KR20130134505A/en not_active Application Discontinuation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20160146086A (en) * | 2015-06-11 | 2016-12-21 | 주식회사 에코마인 | Off-flavor Reducing Method for Seaweed Using Organic Acid Hydrolysis and Supercritical Solvent Drying |
KR102417864B1 (en) | 2022-04-04 | 2022-07-06 | (주)뉴겐코스메틱 | Haircare cosmetic materials for improving condition ofdamagedhair, Manufacturing method thereof and Hair-care products |
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