KR20130101005A - 안정화된 영역을 갖는 glp-1 수용체 효능제 화합물 - Google Patents
안정화된 영역을 갖는 glp-1 수용체 효능제 화합물 Download PDFInfo
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- KR20130101005A KR20130101005A KR1020137005452A KR20137005452A KR20130101005A KR 20130101005 A KR20130101005 A KR 20130101005A KR 1020137005452 A KR1020137005452 A KR 1020137005452A KR 20137005452 A KR20137005452 A KR 20137005452A KR 20130101005 A KR20130101005 A KR 20130101005A
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- xaa
- compound
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Biophysics (AREA)
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- Urology & Nephrology (AREA)
- Immunology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
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| US36852210P | 2010-07-28 | 2010-07-28 | |
| US61/368,522 | 2010-07-28 | ||
| PCT/US2011/045614 WO2012015975A2 (en) | 2010-07-28 | 2011-07-27 | Glp-1 receptor agonist compounds having stabilized regions |
Publications (1)
| Publication Number | Publication Date |
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| KR20130101005A true KR20130101005A (ko) | 2013-09-12 |
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| US (1) | US9217022B2 (enExample) |
| EP (1) | EP2598161A4 (enExample) |
| JP (1) | JP2013535471A (enExample) |
| KR (1) | KR20130101005A (enExample) |
| CN (1) | CN103200956A (enExample) |
| AU (1) | AU2011282745A1 (enExample) |
| BR (1) | BR112013002096A2 (enExample) |
| CA (1) | CA2806749A1 (enExample) |
| EA (1) | EA201390182A1 (enExample) |
| MX (1) | MX2013001131A (enExample) |
| WO (1) | WO2012015975A2 (enExample) |
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| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| CA2895875A1 (en) | 2012-12-21 | 2014-06-26 | Sanofi | Exendin-4 derivatives |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| EP4360651A3 (en) | 2017-08-24 | 2024-07-17 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
| US12527844B2 (en) | 2020-02-18 | 2026-01-20 | Novo Nordisk A/S | Pharmaceutical formulations |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| BR9811866A (pt) * | 1997-08-08 | 2000-08-15 | Amylin Pharmaceuticals Inc | Compostos agonistas de exendina |
| FR2777283B1 (fr) * | 1998-04-10 | 2000-11-24 | Adir | Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US20030087820A1 (en) | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
| EP1976873A2 (en) | 2006-01-11 | 2008-10-08 | Brystol-Myers Squibb Company | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions |
| US8236983B2 (en) * | 2008-03-13 | 2012-08-07 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by apoptosis |
| US7816324B2 (en) * | 2007-03-13 | 2010-10-19 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by a peptide receptor |
| CN101730708B (zh) * | 2007-03-28 | 2013-09-18 | 哈佛大学校长及研究员协会 | 缝合多肽 |
| EP2346906A4 (en) * | 2008-10-15 | 2013-04-24 | Angiochem Inc | CONJUGATES FROM GLP-1 AGONISTS AND THEIR USE |
| EP2413955A4 (en) | 2009-04-01 | 2012-12-26 | Amylin Pharmaceuticals Inc | N-TERMINAL CONFORMATION RESTRICTED GLP-1 RECEPTOR AGONIST COMPOUNDS |
| US9296805B2 (en) * | 2009-06-18 | 2016-03-29 | Dana-Farber Cancer Institute, Inc. | Stabilized insulinotropic peptides and methods of use |
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2011
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- 2011-07-27 MX MX2013001131A patent/MX2013001131A/es unknown
- 2011-07-27 EA EA201390182A patent/EA201390182A1/ru unknown
- 2011-07-27 EP EP11813145.7A patent/EP2598161A4/en not_active Withdrawn
- 2011-07-27 BR BR112013002096A patent/BR112013002096A2/pt not_active IP Right Cessation
- 2011-07-27 CN CN2011800465658A patent/CN103200956A/zh active Pending
- 2011-07-27 US US13/812,445 patent/US9217022B2/en not_active Expired - Fee Related
- 2011-07-27 CA CA2806749A patent/CA2806749A1/en not_active Abandoned
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- 2011-07-27 AU AU2011282745A patent/AU2011282745A1/en not_active Abandoned
- 2011-07-27 JP JP2013521955A patent/JP2013535471A/ja active Pending
Also Published As
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|---|---|
| EA201390182A1 (ru) | 2014-01-30 |
| MX2013001131A (es) | 2013-10-17 |
| JP2013535471A (ja) | 2013-09-12 |
| WO2012015975A2 (en) | 2012-02-02 |
| CN103200956A (zh) | 2013-07-10 |
| AU2011282745A1 (en) | 2013-03-14 |
| WO2012015975A3 (en) | 2012-05-10 |
| BR112013002096A2 (pt) | 2019-09-24 |
| EP2598161A2 (en) | 2013-06-05 |
| CA2806749A1 (en) | 2012-02-02 |
| EP2598161A4 (en) | 2014-02-19 |
| US9217022B2 (en) | 2015-12-22 |
| US20130184203A1 (en) | 2013-07-18 |
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