KR20130093179A

KR20130093179A - 피부관리 제품용 높은 ｄｓ 양이온성 폴리갈락토만난

피부관리 제품용 높은 ｄｓ 양이온성 폴리갈락토만난 Download PDF

Info

Publication number: KR20130093179A
Authority: KR; South Korea
Prior art keywords: weight; cationic; usa; added; skin
Prior art date: 2004-09-24
Legal status : Ceased

Application number

KR1020137020274A

Other languages

English (en)

Korean (ko)

Inventor

자샤완트 제이. 모디

Original Assignee

허큘레스 인코포레이티드

Priority date

2004-09-24

Filing date

2005-09-09

Publication date

2013-08-21

2005-09-09 Application filed by 허큘레스 인코포레이티드 filed Critical 허큘레스 인코포레이티드

2013-08-21 Publication of KR20130093179A publication Critical patent/KR20130093179A/ko

Status Ceased legal-status Critical Current

Links

125000002091 cationic group Chemical group 0.000 title abstract description 123
239000000203 mixture Substances 0.000 claims abstract description 109
239000004094 surface-active agent Substances 0.000 claims abstract description 21
239000004480 active ingredient Substances 0.000 claims abstract description 8
229920006317 cationic polymer Polymers 0.000 claims abstract description 8
238000006467 substitution reaction Methods 0.000 claims abstract description 8
150000001768 cations Chemical group 0.000 claims description 2
239000008186 active pharmaceutical agent Substances 0.000 claims 1
230000003750 conditioning effect Effects 0.000 abstract description 31
230000003020 moisturizing effect Effects 0.000 abstract description 8
230000001153 anti-wrinkle effect Effects 0.000 abstract description 3
230000007123 defense Effects 0.000 abstract description 2
230000008021 deposition Effects 0.000 abstract 1
-1 cationic polysaccharide Chemical class 0.000 description 84
229920000642 polymer Polymers 0.000 description 84
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 72
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 68
244000007835 Cyamopsis tetragonoloba Species 0.000 description 65
MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 description 60
229940073507 cocamidopropyl betaine Drugs 0.000 description 60
239000000243 solution Substances 0.000 description 50
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 48
239000000047 product Substances 0.000 description 48
150000003839 salts Chemical class 0.000 description 46
WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 description 44
239000004615 ingredient Substances 0.000 description 44
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 42
229940057950 sodium laureth sulfate Drugs 0.000 description 40
SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 39
239000008367 deionised water Substances 0.000 description 34
229910021641 deionized water Inorganic materials 0.000 description 34
239000011780 sodium chloride Substances 0.000 description 34
235000013870 dimethyl polysiloxane Nutrition 0.000 description 28
229920000435 poly(dimethylsiloxane) Polymers 0.000 description 28
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 27
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 27
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 26
239000004205 dimethyl polysiloxane Substances 0.000 description 25
229920001296 polysiloxane Polymers 0.000 description 25
BOUCRWJEKAGKKG-UHFFFAOYSA-N n-[3-(diethylaminomethyl)-4-hydroxyphenyl]acetamide Chemical compound CCN(CC)CC1=CC(NC(C)=O)=CC=C1O BOUCRWJEKAGKKG-UHFFFAOYSA-N 0.000 description 24
238000011156 evaluation Methods 0.000 description 23
239000006260 foam Substances 0.000 description 21
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235000019198 oils Nutrition 0.000 description 21
239000000126 substance Substances 0.000 description 21
239000003795 chemical substances by application Substances 0.000 description 19
244000303965 Cyamopsis psoralioides Species 0.000 description 18
239000004166 Lanolin Substances 0.000 description 18
235000019388 lanolin Nutrition 0.000 description 18
229940039717 lanolin Drugs 0.000 description 18
OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 17
238000009472 formulation Methods 0.000 description 17
239000003995 emulsifying agent Substances 0.000 description 16
SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 description 16
239000000499 gel Substances 0.000 description 16
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 16
238000002156 mixing Methods 0.000 description 16
REZZEXDLIUJMMS-UHFFFAOYSA-M dimethyldioctadecylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC REZZEXDLIUJMMS-UHFFFAOYSA-M 0.000 description 15
239000000839 emulsion Substances 0.000 description 15
241000282372 Panthera onca Species 0.000 description 14
229940008099 dimethicone Drugs 0.000 description 14
230000000694 effects Effects 0.000 description 13
235000011187 glycerol Nutrition 0.000 description 13
239000000463 material Substances 0.000 description 13
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 12
235000014113 dietary fatty acids Nutrition 0.000 description 11
239000000194 fatty acid Substances 0.000 description 11
229930195729 fatty acid Natural products 0.000 description 11
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 10
239000007844 bleaching agent Substances 0.000 description 10
238000001816 cooling Methods 0.000 description 10
239000012153 distilled water Substances 0.000 description 10
239000006210 lotion Substances 0.000 description 10
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 10
QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 10
238000012360 testing method Methods 0.000 description 10
NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 9
229920000858 Cyclodextrin Polymers 0.000 description 9
125000000217 alkyl group Chemical group 0.000 description 9
239000003607 modifier Substances 0.000 description 9
239000003755 preservative agent Substances 0.000 description 9
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 8
WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 8
229960000541 cetyl alcohol Drugs 0.000 description 8
238000006243 chemical reaction Methods 0.000 description 8
238000000034 method Methods 0.000 description 8
239000002480 mineral oil Substances 0.000 description 8
239000002562 thickening agent Substances 0.000 description 8
NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 7
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 7
238000005187 foaming Methods 0.000 description 7
150000002430 hydrocarbons Chemical class 0.000 description 7
230000002335 preservative effect Effects 0.000 description 7
238000003756 stirring Methods 0.000 description 7
239000001993 wax Substances 0.000 description 7
239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 6
ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 6
229920002884 Laureth 4 Polymers 0.000 description 6
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 6
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 6
XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 6
125000005250 alkyl acrylate group Chemical group 0.000 description 6
125000000129 anionic group Chemical group 0.000 description 6
235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 6
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
150000004665 fatty acids Chemical class 0.000 description 6
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229940100556 laureth-23 Drugs 0.000 description 6
229940061515 laureth-4 Drugs 0.000 description 6
239000007788 liquid Substances 0.000 description 6
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 6
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 6
229920001282 polysaccharide Polymers 0.000 description 6
239000005017 polysaccharide Substances 0.000 description 6
YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 6
239000011734 sodium Substances 0.000 description 6
239000011550 stock solution Substances 0.000 description 6
235000015112 vegetable and seed oil Nutrition 0.000 description 6
229920001285 xanthan gum Polymers 0.000 description 6
DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 description 5
RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 description 5
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 5
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DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
235000021355 Stearic acid Nutrition 0.000 description 5
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 5
239000002253 acid Substances 0.000 description 5
NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 5
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 5
239000007957 coemulsifier Substances 0.000 description 5
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239000002781 deodorant agent Substances 0.000 description 5
239000000645 desinfectant Substances 0.000 description 5
SOROIESOUPGGFO-UHFFFAOYSA-N diazolidinylurea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 description 5
229960001083 diazolidinylurea Drugs 0.000 description 5
239000003814 drug Substances 0.000 description 5
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125000000524 functional group Chemical group 0.000 description 5
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239000004292 methyl p-hydroxybenzoate Substances 0.000 description 5
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GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 5
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GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 4
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239000004215 Carbon black (E152) Substances 0.000 description 4
XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 4
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
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VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
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ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 4
125000005907 alkyl ester group Chemical group 0.000 description 4
229910052782 aluminium Inorganic materials 0.000 description 4
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
239000003963 antioxidant agent Substances 0.000 description 4
235000006708 antioxidants Nutrition 0.000 description 4
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125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 4
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150000001875 compounds Chemical class 0.000 description 4
235000001671 coumarin Nutrition 0.000 description 4
125000004122 cyclic group Chemical group 0.000 description 4
RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 description 4
ILRSCQWREDREME-UHFFFAOYSA-N dodecanamide Chemical compound CCCCCCCCCCCC(N)=O ILRSCQWREDREME-UHFFFAOYSA-N 0.000 description 4
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150000002148 esters Chemical class 0.000 description 4
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JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 4
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239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 4
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239000001103 potassium chloride Substances 0.000 description 4
235000011164 potassium chloride Nutrition 0.000 description 4
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DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 3
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HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 3
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FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 3
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