KR20130076046A - 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체 - Google Patents

타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체 Download PDF

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Publication number
KR20130076046A
KR20130076046A KR1020110144450A KR20110144450A KR20130076046A KR 20130076046 A KR20130076046 A KR 20130076046A KR 1020110144450 A KR1020110144450 A KR 1020110144450A KR 20110144450 A KR20110144450 A KR 20110144450A KR 20130076046 A KR20130076046 A KR 20130076046A
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South Korea
Prior art keywords
phenyl
disease
pyridin
imidazo
chloro
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KR1020110144450A
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English (en)
Korean (ko)
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이경익
심재의
김호석
하태희
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한미약품 주식회사
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Priority to KR1020110144450A priority Critical patent/KR20130076046A/ko
Priority to CA2859664A priority patent/CA2859664A1/en
Priority to JP2014550009A priority patent/JP2015503552A/ja
Priority to EP12861996.2A priority patent/EP2797909A4/en
Priority to PCT/KR2012/011570 priority patent/WO2013100631A1/en
Priority to BR112014016146A priority patent/BR112014016146A8/pt
Priority to HK15101096.4A priority patent/HK1200811A1/xx
Priority to RU2014131068A priority patent/RU2014131068A/ru
Priority to CN201280064532.0A priority patent/CN104024243A/zh
Priority to MX2014007976A priority patent/MX2014007976A/es
Priority to US14/368,702 priority patent/US20150299185A1/en
Priority to AU2012363557A priority patent/AU2012363557A1/en
Publication of KR20130076046A publication Critical patent/KR20130076046A/ko
Priority to IL233415A priority patent/IL233415A0/en
Priority to ZA2014/05505A priority patent/ZA201405505B/en
Withdrawn legal-status Critical Current

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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  • Pain & Pain Management (AREA)
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KR1020110144450A 2011-12-28 2011-12-28 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체 Withdrawn KR20130076046A (ko)

Priority Applications (14)

Application Number Priority Date Filing Date Title
KR1020110144450A KR20130076046A (ko) 2011-12-28 2011-12-28 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체
RU2014131068A RU2014131068A (ru) 2011-12-28 2012-12-27 Новые производные имидазопиридина в качестве ингибиторов тирозинкиназы
CN201280064532.0A CN104024243A (zh) 2011-12-28 2012-12-27 作为酪氨酸激酶抑制剂的新咪唑并吡啶衍生物
EP12861996.2A EP2797909A4 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinin inhibitor
PCT/KR2012/011570 WO2013100631A1 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor
BR112014016146A BR112014016146A8 (pt) 2011-12-28 2012-12-27 derivados de imidazopiridina como um inibidor de tirosina quinase
HK15101096.4A HK1200811A1 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor
CA2859664A CA2859664A1 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor
JP2014550009A JP2015503552A (ja) 2011-12-28 2012-12-27 チロシンキナーゼ阻害剤としての新規イミダゾピリジン誘導体
MX2014007976A MX2014007976A (es) 2011-12-28 2012-12-27 Derivados de imidazopiridina novedosos como un inhibidor de tirosina cinasa.
US14/368,702 US20150299185A1 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor
AU2012363557A AU2012363557A1 (en) 2011-12-28 2012-12-27 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor
IL233415A IL233415A0 (en) 2011-12-28 2014-06-26 Imidazopyridine derivatives of tyrosine kinase inhibitors, preparations containing them and their uses
ZA2014/05505A ZA201405505B (en) 2011-12-28 2014-07-25 Novel imidazopyridine derivatives as a tyrosine kinase inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020110144450A KR20130076046A (ko) 2011-12-28 2011-12-28 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체

Publications (1)

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KR20130076046A true KR20130076046A (ko) 2013-07-08

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KR1020110144450A Withdrawn KR20130076046A (ko) 2011-12-28 2011-12-28 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체

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Country Link
US (1) US20150299185A1 (enExample)
EP (1) EP2797909A4 (enExample)
JP (1) JP2015503552A (enExample)
KR (1) KR20130076046A (enExample)
CN (1) CN104024243A (enExample)
AU (1) AU2012363557A1 (enExample)
BR (1) BR112014016146A8 (enExample)
CA (1) CA2859664A1 (enExample)
HK (1) HK1200811A1 (enExample)
IL (1) IL233415A0 (enExample)
MX (1) MX2014007976A (enExample)
RU (1) RU2014131068A (enExample)
WO (1) WO2013100631A1 (enExample)
ZA (1) ZA201405505B (enExample)

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CN105837572B (zh) * 2015-02-02 2019-04-19 四川大学 N-取代苯基酰胺衍生物及其制备方法和用途
US11008318B2 (en) * 2016-07-11 2021-05-18 Kancera Ab 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity
US11590167B2 (en) 2016-12-03 2023-02-28 Juno Therapeutic, Inc. Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
EP3976612A4 (en) * 2019-05-28 2023-04-26 Mankind Pharma Ltd NEW COMPOUNDS FOR INHIBITION OF JANUS KINASE 1
US20240100172A1 (en) 2020-12-21 2024-03-28 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy

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EP2797909A4 (en) 2015-06-10
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MX2014007976A (es) 2014-08-21
ZA201405505B (en) 2015-10-28
BR112014016146A8 (pt) 2017-07-04
EP2797909A1 (en) 2014-11-05
US20150299185A1 (en) 2015-10-22
CA2859664A1 (en) 2013-07-04
AU2012363557A1 (en) 2014-07-17
RU2014131068A (ru) 2016-02-20
IL233415A0 (en) 2014-08-31
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BR112014016146A2 (pt) 2017-06-13
WO2013100631A1 (en) 2013-07-04

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