KR20120121272A - 5 Subject Hair Care Material - Google Patents

5 Subject Hair Care Material Download PDF

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Publication number
KR20120121272A
KR20120121272A KR1020110039153A KR20110039153A KR20120121272A KR 20120121272 A KR20120121272 A KR 20120121272A KR 1020110039153 A KR1020110039153 A KR 1020110039153A KR 20110039153 A KR20110039153 A KR 20110039153A KR 20120121272 A KR20120121272 A KR 20120121272A
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South Korea
Prior art keywords
hair
composition
weight
promoting
black sesame
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KR1020110039153A
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Korean (ko)
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노효만
이영수
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노효만
이영수
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Priority to KR1020110039153A priority Critical patent/KR20120121272A/en
Publication of KR20120121272A publication Critical patent/KR20120121272A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction

Abstract

PURPOSE: A composition containing natural products is help scalp blood circulation, to promote hair growth, and to prevent hair loss. CONSTITUTION: A composition for promoting hair growth contains extracts of red pepper, black sesame, Gardeniae Fructus, Bletillae Rhizoma, and polygonum indigo. The extracts are prepared by supercritical extraction. The composition contains 0.1-5.0 wt% of red pepper, 1.0-50.0 wt% of black sesame, 1.0-40.0 wt% of Gardeniae Fructus, 1.0-40.0 wt% of Bletillae Rhizoma, and 0.5-10.0 wt% of polygonum indigo. The composition is manufactured in the form of a hair shampoo, hair tonic, hair rinse, hair treatment, hair conditioner, and hair lotion.

Description

고추, 검정깨, 치자, 백급, 쪽풀을 함유하는 발모촉진용 조성물 특허{5 Subject Hair Care Material }Patent for hair-promoting composition containing red pepper, black sesame seeds, gardenia, white powder and buckwheat {5 Subject Hair Care Material}

본 발명은 발모 촉진용 조성물 및 이를 이용한 제품에 관한 것으로, 상세하게는 두피의 탈모부위에 도포하여 모발의 성장 및 발모를 촉진하기 위한 혼합조성물로 고추, 검정깨, 치자, 백급, 쪽풀을 아임계 추출법으로 추출한 혼합물로 조성된 것이며, 이를 두발용 화장료에 혼합하여 탈모부위에 적용하면 부작용 및 독성이 전혀 없고 두피와 모발에 영양을 공급하고 두피 혈행을 도와 탈모의 예방 및 모발 성장 촉진에 효과가 있게 한 모발의 성장 촉진 및 발모촉진용 혼합조성물과 이를 이용한 제품에 관한 것이다. The present invention relates to a composition for promoting hair growth and a product using the same, and in particular, red pepper, black sesame, gardenia, white, and green grass as a mixed composition for promoting hair growth and hair growth by applying to the hair loss site of the scalp. It is composed of a mixture extracted by the extraction method, and when mixed with the hair cosmetics and applied to the hair loss site, there are no side effects and toxicity, it nourishes the scalp and hair, helps the scalp blood circulation, and is effective in preventing hair loss and promoting hair growth. It relates to a composition for promoting growth and hair growth of a hair and a product using the same.

일반적으로 모발은 약 10만개~15만개 정도이며 각각의 모발은 서로 다른 모주기를 가지고 모발을 성장시키는 성장기(anagen), 성장을 종료하고 모구부가 축소하는 퇴화기(catagen), 모유두가 활동을 멈추고 모발을 두피에 머무르게 하는 휴지기(telogen)를 돌며 발모와 탈모를 반복하는데, 그 결과 전체 모발의 약 15%에 해당하는 모발이 휴지기와 퇴화기에 놓여 있어 일 평균 50~100개의 모발이 정상적으로 탈락하고 재생산된다. 그리고, 탈모증은 모 주기의 성장기에 해당하는 기간이 여러 가지 원인으로 인해 짧아져 퇴화기와 휴지기 모발의 비율이 상대적으로 많아져 모발이 탈락하는 수가 평균치보다 많아지는 것을 말한다. Generally, there are about 100,000 to 150,000 pieces of hair, and each hair has a different hair cycle, an anagen for growing hair, a catagen that terminates growth and shrinks the hairball, and the nipple stops working. Repeats hair loss and hair loss by telogen, which keeps the hair on the scalp. As a result, about 15% of the hair is placed in the rest period and in the period of degeneration, so that on average 50 to 100 hairs fall out normally and reproduce. do. In addition, alopecia is a period in which the growth phase of the hair cycle is shortened due to various causes, and the ratio of degenerative and resting hair increases relatively, so that the number of hair dropouts is higher than the average value.

이러한 모발의 탈모현상에 대해 아직 정확한 원인이 밝혀져 있지 않고 있으며, 이에 대해서는 여러 가지 가설이 있다. 즉, 호르몬의 불균형에 의해 발생한다는 호르몬설, 급격한 정신적 고통때문이라는 스트레스설, 외부 유해환경에 의해 생기는 외부오염설, 비듬과다로 분비불이 섞인 피지류가 모근을 막아 영양공급을 방해하여 발생한다는 과잉피지분비설, 동물성 지방등의 과잉 섭취로 인한 혈류 방해로 인해 영양공급이 안되어 일어난다는 동물성 지방 과영양설과 혈액순환장애 때문이라는 혈액순환장애설 등이 있다.
The exact cause of hair loss is not known yet, and there are various hypotheses. In other words, hormonal theory caused by hormonal imbalance, stress theory due to sudden mental pain, external pollution caused by external harmful environment, and sebum mixed with secretion fire due to excessive dandruff block the hair roots and interfere with nutrition supply. Excess sebum secretion, animal fats, such as excessive blood intake due to obstruction of blood flow due to animal fat over-nutrition and blood circulation disorders due to blood circulation disorders.

이처럼 탈모는 한가지 원인으로 발생하는 것이 아니라 여러 가지 원인이 복합적으로 작용한다. 최근 들어 식생활의 변화, 사회환경 등에 의한 스트레스의 증가 등으로 탈모로 고민하는 인구가 늘어나고 있는 추세이며, 그 연령 또한 낮아지고 여성의 탈모 인구도 늘어나고 있는 실정이다.
As such, hair loss does not occur as a single cause, but a combination of various causes. In recent years, the number of people who suffer from hair loss due to changes in diet, social stress, etc. is increasing, and the age is also decreasing and the hair loss population of women is increasing.

이처럼 다양하고 복잡한 탈모원인에 대하여, 시중에 판매되는 발모제로는 미국의 식품의약품안전청(FDA)에서 승인받은 미국특허 제 3,382,247의 미녹시딜(minoxidile)과 경구용 제제로 사용되어지고 있는 미국특허 제 5,215,894호에서 언급된 피나스테라이드(finasteride)등이 있다. 그러나 미녹시딜은 끈적이는 사용감과 피부자극을 유발하는 부작용이 보고된 바 있고, 피나스테라이드는 성기능 장애 등의 부작용이 보고된 일이 있을 뿐만 아니라, 꾸준한 적용이 이루어져야만 효과가 있고, 이를 포함한 5알파-리덕타아제 활성 억제제를 도포에 의한 효과를 기대하기 어렵고, 경구복용에 의해서만 효과를 기대할 수 있어서 사용상에 많은 불편함이 있다. For such diverse and complex causes of hair loss, commercially available hair regrowth agents include U.S. Patent No. 5,215,894, which is used as a minoxidil and oral formulation of U.S. Patent No. 3,382,247, approved by the US Food and Drug Administration (FDA). Finasteride mentioned in However, minoxidil has been reported to cause side effects such as sticky feeling and skin irritation, and finasteride has been reported to have side effects such as sexual dysfunction, and it is effective only when steady application is made, including 5 alpha-reducta. It is difficult to expect the effect of the application of an activator inhibitor, and the effect can be expected only by oral administration, which causes a lot of inconvenience in use.

본 발명은 종래 탈모방지 및 발모를 위해 사용되는 발모제에 여러 가지 문제점을 가짐에 따라 탈모예방 및 발모촉진에 효과가 우수한 조성물에 대해 지속적으로 연구한 결과 새로운 모발의 성장촉진 및 발모촉진제 조성물을 제안하고자 하는 것이며, 본 발명의 목적은 고추, 검정깨, 치자, 백급, 쪽풀의 혼합조성물이 모발성장촉진 및 발모촉진에 효과가 있음을 확인하여, 피부에 부작용과 독성이 없는 우수한 모발성장촉진 및 발모촉진용 조성물과 이를 이용한 제품을 제공하는데 있다.
The present invention is to propose a new hair growth promoting and hair growth promoting agent composition as a result of the continuous research on the composition excellent in preventing hair loss and promoting hair growth according to the conventional hair loss agent used for preventing hair loss and hair growth The purpose of the present invention is to confirm that the mixed composition of red pepper, black sesame, gardenia, baekrye, buckwheat is effective in promoting hair growth and hair growth, and promotes excellent hair growth and hair growth without side effects and toxicity to the skin. To provide a composition and a product using the same.

이상에서 살펴본 바와 같이 본 발명의 모발의 성장촉진 및 발모촉진용 조성물은 고추, 검정깨, 치자, 백급, 쪽풀을 혼합조성하여 아임계 추출법으로 추출한 조성물로써, 종래 양약에 근원을 둔 화학제 종류의 발모제가 갖는 부작용을 최소화할 수 있는 효과가 있으며, 본 발명의 조성물에 헤어샴푸원료, 헤어토닉원료 등을 각각 일정비율로 혼합함으로써, 상기와 같이 모발과 두피에 영양을 공급하고 혈행을 촉진하여 탈모의 예방 및 모발의 성장을 촉진하는 발모촉진용 두발화장품에 적용될 수 있다.
As described above, the hair growth promoting and hair growth promoting composition of the present invention is a composition extracted from the subcritical extraction method by mixing red pepper, black sesame, gardenia, white, and green grass, and has a kind of chemicals based on conventional medicines. It has the effect of minimizing the side effects of the hair regrowth agent, by mixing hair shampoo ingredients, hair tonic ingredients and the like in the composition of the present invention at a certain ratio, thereby supplying nourishment to the hair and scalp and promoting blood circulation as described above. It can be applied to hair cosmetics for promoting hair growth which prevents and promotes hair growth.

상기와 같은 목적을 당성하기 위한 본 발명의 조성물은 고추, 검정깨, 치자, 백급, 쪽풀을 포함하고, 그 중량비가 전체 중량%에 대하여 각각 0.1중량%~5.0중량% : 1.0중량%~50.0중량% : 1.0중량%~40.0중량% : 1.0중량%~40.0중량% : 0.5중량%~10.0중량% 이고, 바람직하게는 1.0중량% : 40.0중량% : 30.0중량% : 25.0중량% : 4.0중량% 일 수 있다.The composition of the present invention for achieving the above object comprises red pepper, black sesame, gardenia, white, buckthorn, the weight ratio of each 0.1% to 5.0% by weight: 1.0% to 50.0% by weight relative to the total weight% %: 1.0 wt% to 40.0 wt%: 1.0 wt% to 40.0 wt%: 0.5 wt% to 10.0 wt%, preferably 1.0 wt%: 40.0 wt%: 30.0 wt%: 25.0 wt%: 4.0 wt% Can be.

상기 조성물 추출물은 아임계 추출법에 의해 추출된 것을 특징으로 한다. 여기서 아임계 추출법(subcritical water extraction, SWE)은 약 15년 전부터 분석 시료의 전처리 기술로 활용되어 왔으나 최근에는 천연물로부터 극성 및 비극성 천연색소, 향 등의 유효성분을 추출하는 방법으로써의 연구가 미국, 유럽, 일본 등의 선진국을 중심으로 세계적으로 진행되고 있다. 추출용매로 아임계 상태의 물(subcritical water)을 사용하며 이 물은 낮은 상대유전율(1<<25)로 인해 플라보노이드와 같은 비극성화합물(non-polar compound)을 추출하는데 있어 매우 효과적이다. 온도와 압력조건 변경은 물을 용매로 하여 모든 특성의 추출물을 획득할 수 있게 된다. 물은 값이 싸고 독이 없으며 사용 후 안전하게 폐기할 수 있을 뿐만 아니라 압력조절에 의하여 끓는점을 변화시킴으로써 간단하게 속성을 바꿀 수 있으므로 목적에 따라 유효성분 추출에 다양하게 이용될 수 있으며 추출 매체로써 유기용매를 이용하는 많은 전통적인 추출기법과 비교하여 아임계 추출방법은 더 용이한 선택성(selectivity)을 보유하기 때문에 불순물(interfering compounds)을 적게 포함하도록 유효성분을 추출할 수 있는 장점을 가진다.
The composition extract is characterized in that extracted by subcritical extraction. Subcritical water extraction (SWE) has been used as a pretreatment technique for analytical samples for about 15 years, but recently, as a method of extracting active ingredients such as polar and nonpolar natural pigments and flavors from natural products, the US, It is progressing worldwide, especially in developed countries such as Europe and Japan. Subcritical water is used as the extraction solvent, which is very effective for extracting non-polar compounds such as flavonoids due to the low relative dielectric constant (1 << 25). Changing temperature and pressure conditions allows the extraction of all properties using water as a solvent. Water is inexpensive, non-toxic and can be disposed of safely after use, as well as simply changing its properties by changing the boiling point by pressure control, so it can be used in various ways to extract active ingredients according to the purpose. The subcritical extraction method has the advantage of extracting the active ingredient to contain less interfering compounds, because it has easier selectivity compared to many conventional extraction methods used.

그리고, 본 발명은 상기 추출법을 통해 얻은 혼합조성물에 샴푸원료, 트리트먼트원료, 헤어토닉원료 등을 각각 일정비율로 혼합함으로써, 두피와 모발에 영양을 공급하여 모발성장촉진 및 탈모방지에 효과가 있는 발모촉진용 제품을 제조 공급하는데 그 특징이 있다.
In addition, the present invention by mixing the shampoo raw material, the treatment raw material, the hair tonic raw material and the like into the mixed composition obtained through the extraction method in a certain ratio, respectively, supplying nourishment to the scalp and hair, which is effective in promoting hair growth and preventing hair loss. It is characterized by manufacturing and supplying hair growth promoting products.

여기서, 본 발명에 따른 상기 혼합조성물 중 고추는 주성분이 캡사이신이며 혈액순환촉진기능이 있어 혈행을 개선하고 두피에 자극을 주어 모근세포를 활성화하여 발모를 촉진하는 기능이 있다.
Here, the red pepper of the mixed composition according to the present invention is the main component is capsaicin and has a blood circulation promoting function to improve blood circulation and stimulate the scalp to activate hair root cells to promote hair growth.

본 발명에 따른 혼합조성물 중 검정깨는 일본과 중국에서 탈모와 대머리로 고민하는 사람들이 선호하는 자연요법으로 애용하였으며, 특히 중국에서는 머리카락의 질을 높여주기 위해서는 간을 강화시켜주고, 혈행을 촉진시켜야 하는데, 이를 위한 최적의 식품으로 검은깨를 애용해왔다. 이와 같이 검은깨는 양질의 단백질이 품부하고, 비타민E를 함유하고 있는 리놀렌산, 칼슘, 비타B1, B2, 철분 등이 많이 들어있어 모발에 필요한 영양을 공급해 주는 동시에 혈액의 콜레스테롤 수치를 줄여주고 있다. 또한 풍부하게 함유된 리놀산, 리놀렌산 등의 불포화 지방산은 혈액을 부드럽게 해주며, 비타민E는 말초혈관의 혈류를 촉진시키는 등의 신진대사를 조절해주고 있다. 특히 검은깨에 함유하고 있는 트립토판(tryptophan)은 피부를 깨끗하게 해주고 머리카락에 윤기를 주는 작용을 하고 있다. 이외에도 검은깨의 주성분인 레시친은 지방운반을 도와주어 모세혈관의 혈액순환을 촉진시키고 모발의 뿌리부분(모근)까지 필요한 영양소를 공급해주는 동시에 콜레스테롤이 체내에 쌓이지 않게 함으로써 동맥경화를 예방하는데 효과가 있으며, 신장기능도 강화시켜 주는 효과가 있음이 알려져 있다.
The black sesame among the mixed composition according to the present invention was favored as a natural therapy preferred by those who suffer from hair loss and baldness in Japan and China, and especially in China, it is necessary to strengthen the liver and promote blood circulation to improve hair quality. Black sesame has been a favorite food for this purpose. As such, black sesame seeds contain high quality protein and contain vitamin E-containing linolenic acid, calcium, vitamin B1, B2, and iron, which provide the hair with nutrition and reduce blood cholesterol levels. In addition, abundant unsaturated fatty acids such as linoleic acid and linolenic acid soften blood, and vitamin E regulates metabolism, such as promoting blood flow in peripheral blood vessels. In particular, tryptophan, which is contained in black sesame, works to cleanse the skin and to shine the hair. In addition, lecithin, the main ingredient of black sesame seeds, helps to transport fat, promotes blood circulation in capillaries, provides the necessary nutrients to the root of the hair (hair roots), and prevents arteriosclerosis by preventing cholesterol from accumulating in the body. It is also known that it is effective in strengthening kidney function.

본 발명에 따른 혼합조성물 중 치자는 한방에서 불면증과 황달의 치료에 쓰고 소염, 지혈 및 이뇨작용이 있다고 알려져 있다. 음식물의 착색제로 쓰고, 옛날에는 군량미의 변질을 막기 위해 치자물에 담갔다가 쪄서 저장하였다고 한다.
Gardenia of the mixed composition according to the present invention is known to have anti-inflammatory, hemostatic and diuretic effects in the treatment of insomnia and jaundice in oriental medicine. It is used as a colorant for food, and in the old days, it was stored in gardenia water and steamed to prevent deterioration of military taste.

본 발명에 따른 혼합조성물 중 백급은 동의학 사전에는 가을에 덩이뿌리를 캐서 물에 씻어 증기에 쪄서 말린다. 맛은 쓰고 달며 성질은 서늘하다. 폐경에 작용한다. 폐를 보하고 피나는 것을 멈추며, 부은 것을 내리고 새살이 잘 돋아나게 한다.라고 되어 있고, 수진방(袖珍方)에서는 정창의 중독치료에 백급분말 0.5돈을 물에 침전시킨 후 물을 제거하고 두꺼운 종이에 펴서 바른다고 한다. 또한 제급선방(濟急仙方)에서는 화상의 치료에 사용한다고 나와 있다. 또한 약리 작용으로 지혈작용, 위 및 십이지장궤양 치료작용, 억균작용 등이 있음이 밝혀졌다. In the mixed composition according to the present invention, the weight is dried in steam by digging the tuber in the fall in the synonym beforehand in water. The taste is bitter and sweet, and the nature is cool. Acts on menopause The lungs are stopped, the blood stops to stop, the swollen water is lowered, and the new flesh is well sprouted.In Sujinbang, the powder of water is precipitated by depositing 0.5 pounds of white powder in water for the treatment of intestinal poisoning. Spread it on. In addition, it is said that it is used for the treatment of burns in the emergency class. In addition, it has been found that pharmacological actions include hemostatic action, gastric and duodenal ulcer treatment action, and fungal action.

본 발명에 따른 혼합조성물 중 쪽풀은 주로 천연염료로 많이 사용되었으며 즙을 내어 벌레물린 곳이나 곪은 곳에 주로 사용되고 항균, 살균, 항취의 기능이 당해 두피 트러블의 문제를 해소해 준다.
The mixture of the composition according to the present invention is mainly used as a natural dye is mainly used in the place of insect bites or squeezed juice and the function of antibacterial, sterilization, deodorant solves the problem of the scalp trouble.

이하, 본 발명의 바람직한 실시 예를 더욱 상세하게 설명하면 다음과 같다.
Hereinafter, preferred embodiments of the present invention will be described in more detail.

[제조예 1] 고추, 검정깨, 치자, 백급, 쪽풀 혼합조성추출물의 제조방법Preparation Example 1 Method for Producing Extract of Red Pepper, Black Sesame Seed, Gardenia, White Grain, and Squash Mix Composition

본 실험에 사용된 시료들은 모두 국내산인 것을 얻어 각각의 고추, 검정깨, 치자, 백급, 쪽풀을 60에서 10시간 동안 열풍 건조한 후 고속믹서기를 이용하여 분말화 하였다. 상기 고추, 검정깨, 치자, 백급, 쪽풀은 추출과정을 진행함에 있어서, 추출용매와의 접촉 면적을 최대로 증가시켜 추출수율을 높이기 위해 분말 형태로 제조할 수 있다. 따라서 본 발명의 고추, 검정깨, 치자, 백급, 쪽풀 시료를 제조하는 단계에는 상기 5가지 조성물을 분말화하는 과정이 추가로 포함될 수 있다. 상기 분말화 과정을 통해 제조된 각각의 분말을 0.1~5.0%중량 : 1.0~50%중량 : 1.0~40%중량 : 1.0~40%중량 : 0.5~10.0%중량의 비로, 바람직하게는 1.0%중량 : 40%중량 : 30%중량 : 25%중량 : 4%중량의 비로 계량하고 혼합하여 아임계 추출법을 수행할 시료를 제조하였다. 상기 아임계 추출에 사용될 아임계 유체는 물, 이산화탄소, 에틸렌, 에탄, 프로판, 아세틸렌 또는 암모니아 등일 수 있고, 바람직하게는 경제적이고 유해성분이 없으며 안전하게 폐기할 수 있어 친환경적인 물, 더욱 바람직하게는 아임계 수 일 수 있다. 상기 아임계 수란 아임계 조건의 물을 의미할 수 있다. 상기 아임계 추출법은 상기 아임계 수의 압력이 800 내지 1800psi 바람직하게는 1300 내지 1700psi 이고, 상기 아임계 수의 온도는 130 내지 190 바람직하게는 160 내지 170 일 수 있다. 운반체는 질소가스일 수 있다.The samples used in this experiment were all domestic, and each hot pepper, black sesame, gardenia, white, and grass were dried with hot air for 60 to 10 hours and then powdered using a high speed mixer. The red pepper, black sesame seeds, gardenia, baekryeum, buckwheat can be prepared in powder form to increase the extraction area to the maximum by increasing the contact area with the extraction solvent in the extraction process. Therefore, the step of preparing a red pepper, black sesame, gardenia, white, buckwheat sample of the present invention may further include the process of powdering the five compositions. Each powder prepared through the powdering process is 0.1 to 5.0% by weight: 1.0 to 50% by weight: 1.0 to 40% by weight: 1.0 to 40% by weight: 0.5 to 10.0% by weight of ratio, preferably 1.0% by weight : 40% by weight: 30% by weight: 25% by weight: 4% by weight in a ratio of the sample was prepared by performing a subcritical extraction method. The subcritical fluid to be used for the subcritical extraction may be water, carbon dioxide, ethylene, ethane, propane, acetylene or ammonia, and is preferably economical, no harmful components and can be safely disposed of, thus being environmentally friendly, more preferably subcritical. Can be. The subcritical water may mean water under subcritical conditions. In the subcritical extraction method, the pressure of the subcritical water is 800 to 1800 psi, preferably 1300 to 1700 psi, and the temperature of the subcritical water may be 130 to 190, preferably 160 to 170. The carrier may be nitrogen gas.

본 발명의 제조예인 고추, 검정깨, 치자, 백급, 쪽풀의 혼합조성 아임계 추출은 상기 5가지 혼합조성분말 4g을 34ml size 셀(cell)에 넣고 상기 셀을 아임계 추출기(DIONEX Accelerated Solvent Extractor(ASE) 100, DIONEX co., USA)에 장착한 후 추출용매로 증류수만을 사용하여 100 내지 190의 온도에서, 5분 내지 30분의 시간으로 아임계 추출을 수행하였다. 상기 시료에 압력을 가하여 1300 내지 1900psi의 압력조건 및 상기 추출 온도 조건에서 수행하였고 운반체로 질소가스를 사용하였다. 혼합조성추출물을 포집기로 회수하여 본 발명에 사용되는 발모촉진용 조성물로 사용하였다. 이때, 본 발명의 발모촉진용 조성물에는 또한 필요에 따라 탈모방지와 육모를 증진시킬 수 있는 하나 또는 그 이상의 통상적인 배합성분이 초산토코페롤, 살리실산, 니코틴산아미드, L-멘톨, DL-판테놀 등이 포함될 수 있으며, 샴푸, 헤어컨디셔너, 헤어토닉, 헤어모이스쳐라이저 등 통상 두피에 적용시킬 수 있는 모든 제형이 가능한다. The subcritical extraction of the red pepper, black sesame, gardenia, white, and green grass, which is a preparation example of the present invention, puts 4 g of the five mixed crude powders in a 34 ml size cell and puts the cells in a subcritical extractor (DIONEX Accelerated Solvent Extractor) ASE) 100, DIONEX co., USA) and then subcritical extraction was performed at a temperature of 100 to 190 minutes for 5 minutes to 30 minutes using only distilled water as the extraction solvent. The sample was pressurized under pressure conditions of 1300 to 1900 psi and the extraction temperature, and nitrogen gas was used as a carrier. The mixed composition extract was collected by a collector and used as a composition for promoting hair growth used in the present invention. In this case, the composition for promoting hair growth of the present invention may also include tocopherol acetate, salicylic acid, nicotinic acid amide, L-menthol, DL-panthenol, etc., which may include one or more conventional blending ingredients that may promote hair loss prevention and hair growth, if necessary. All formulations that can be applied to the scalp, such as shampoo, hair conditioner, hair tonic, hair moisturizer, are possible.

그러므로, 본 발명은 상기와 같은 발모촉진용 조성물에 샴푸원료, 헤어트리트먼트원료, 헤어토닉원료 등을 각각 일정비율로 혼합함으로써, 두피와 모발에 영양을 공급하여 모발성장촉진 및 탈모예방에 효과가 있는 모발성장촉진 및 탈모촉진용 제품을 제조 공급하는데 그 특징이 있다.
Therefore, the present invention is to mix the shampoo raw material, hair treatment raw material, hair tonic raw material and the like with the hair growth composition as described above in a certain ratio, thereby supplying nourishment to the scalp and hair to promote hair growth and prevent hair loss. It is characterized by manufacturing and supplying products for promoting hair growth and hair loss.

이하 본 발명을 하기 위한 실시예에 의거 더욱 구체적으로 발모촉진용 조성물 및 이를 이용한 제품의 제조과정을 살펴보기로 한다. Hereinafter, the composition for promoting hair growth and the manufacturing process of the product using the same will be described in more detail based on the embodiments for carrying out the present invention.

이때, 본 발명이 다음 실시예에 한정된 것은 아니다.
At this time, the present invention is not limited to the following examples.

[[ 실시예1Example 1 ]]

고추, 검정깨, 치자, 백급, 쪽풀을 앞서 [제조예1]의 방법으로 혼합조성추출물을 얻어내어 1마이크로() 입경이 통과되는 눈금을 갖는 여과지(Advantec사)로 1회 여과한 후 다시 0.45마이크로() 입경이 통과되는 눈금을 갖는 여과지(Advantec사)로 1회 여과하여 제품에 적용 될 실 조성물을 만들어낸다. Red pepper, black sesame seeds, gardenia, white urchin, and buckwheat were obtained by mixing the extract of the composition by the method of [Preparation Example 1], and once filtered with a filter paper (Advantec) having a graduated diameter of 1 micro (). Filtered once with a filter paper (Advantec) with a graduated micro () particle diameter to produce a seal composition to be applied to the product.

그런 다음, 상기에서 수득한 혼합물을 샴푸원료인 라우릭에씨드 디에탄올 아미드(Lauric Acid Diethanol Amide) 5내지 10중량%, 소듐 라우릴 에테르 설페이드(Sodium Lauryl Ether Sulfate)10내지 30중량%, 코카미도프로필 베타인(Cocamidopropyl Betain) 5내지 10중량% 및 정제수 1내지 50중량%를 각각 혼합하여 만든 발모촉진용 샴푸 혼합액과 1:9내지 3:7의 비율로 혼합하여 발모촉진용 샴푸 혼합액을 만들 수 있다. Then, the mixture obtained above is 5 to 10% by weight of lauric acid diethanol amide (shampoo material), 10 to 30% by weight of sodium lauryl ether sulfate, coca A hair growth promoting shampoo mixture made by mixing 5 to 10% by weight of midopropyl betaine (Cocamidopropyl Betain) and 1 to 50% by weight of purified water and a ratio of 1: 9 to 3: 7 to make a hair growth promoting shampoo mixture Can be.

이렇게 제조된 본 발명의 발모촉진용 헤어샴푸를 탈모자 30명에게 하루에 1회씩 사용하도록 한 후, 16주 동안의 두피 상태 및 모발상태를 관찰하였다.
The hair shampoo for hair growth promotion of the present invention thus prepared was used once a day for 30 depilators, and the scalp state and hair condition for 16 weeks were observed.

시험의 방법으로는 다음 기준을 모두 만족하는 사람만을 실험대상으로 하였다. As a test method, only those who satisfy all of the following criteria were tested.

20세 이상의 신체적 및 정신적 건강상태가 양호한 남성 및 여성으로써 탈모가 진행되는 자  Men and women with good physical and mental health who are 20 years of age or older and who are experiencing hair loss

실험기간 동안 동일한 머리 모양을 유지할 자  Maintain the same hair throughout the experiment

실험기간 동안 염색 및 퍼머를 하지 않을 자  Those who will not dye and perm during the experiment

실험기간 동안 특별한 모발용품이나 모발관리 및 조작을 하지 않을 자  No special hair care products or hair care and manipulation during the experiment

탈모자들의 일반적인 모발과 두피의 상태를 고려하여, 본 발모촉진용 조성물을 함유한 샴푸를 사용한 후 개선되는 정도가 확연히 느낄 수 있는 상태일때 만을 개선되었음에 표기하도록 설문하였고 탈모수 개선에 대한 명확한 답을 얻기 위해 세발 후 실제 빠진 머리카락 수를 주 1회씩 합계하여 표기하도록 하였다.
Considering the general condition of hair and scalp of the hair loss people, the questionnaire was written to indicate that it was improved only when the degree of improvement was obvious after using the shampoo containing the hair growth promoting composition. In order to obtain the total number of hair lost after the three times a week to write the sum.

<표1><Table 1>

Figure pat00001

Figure pat00001

[[ 실시예2Example 2 ]]

고추, 검정깨, 치자, 백급, 쪽풀을 앞서 [제조예1]의 방법으로 혼합조성추출물을 얻어내어 1마이크로() 입경이 통과되는 눈금을 갖는 여과지 (Adevantec사)로 1회 여과한 후 다시 0.45마이크로() 입경이 통과되는 눈금을 갖는 여과지 (Adevantec사)로 1회 여과하여 제품에 적용될 실 조성물을 만들어 낸다.Red pepper, black sesame seeds, gardenia, white urchin, and green grass were obtained by mixing the extract of the composition by the method of [Preparation Example 1], and filtered once with a filter paper (Adevantec) having a scale of 1 micro () particle diameter, and then again 0.45. Filtering once with a filter paper (Adevantec Co., Ltd.) with a graduated micro () particle diameter to produce a seal composition to be applied to the product.

그런 다음, 상기에서 수득한 혼합물을, 정제수 1내지50중량%, 에탄올 10내지40중량%, 부틸렌글리콘 1내지5중량%, 글리세린 1내지5중량%, L-멘톨 0.1내지2중량%, DL-캄퍼 0.1내지1중량%, 살리실산 0.1내지1중량%를 각각 혼합하여 만든 헤어토닉 혼합액과 2:8내지 5:5 비율로 혼합하여 발모촉진용 헤어토닉 조성물을 만든다. Then, the mixture obtained above is 1 to 50% by weight of purified water, 10 to 40% by weight of ethanol, 1 to 5% by weight of butylene glycol, 1 to 5% by weight of glycerin, 0.1 to 2% by weight of L-menthol, DL -0.1 to 1% by weight of camphor, 0.1 to 1% by weight of salicylic acid and mixed with a hair tonic mixture of 2: 8 to 5: 5 ratio to make a hair tonic composition for promoting hair growth.

이렇게 제조된 본 발명의 발모촉진용 헤어토닉을 탈모자 30명에게 하루에 2회씩 사용하도록 한 후, 16주 동안의 두피상태 및 모발상태를 관찰하였다. 실험방법과 대상자 선정은 앞서 [실시예1]의 경우와 같다. After the hair tonic for promoting hair growth of the present invention prepared 30 people were used twice a day, scalp state and hair condition for 16 weeks were observed. Experimental method and subject selection is the same as in the case of [Example 1].

이들을 대상으로 한 임상실험의 결과는 아래 <표2>에 표시하였다.
The results of clinical trials involving these subjects are shown in Table 2 below.

<표2><Table 2>

Figure pat00002

Figure pat00002

상기결과의 <표1>, <표2>를 고찰해 볼 때, 탈모의 원인이 되는 두피가려움증, 비듬, 피지량이 상당히 개선되는 효과가 있고, 탈모의 예방 및 발모촉진에도 확실히 효과가 있음을 알 수 있다. Considering <Table 1> and <Table 2> of the above results, the scalp itching, dandruff, and sebum amount that causes hair loss are significantly improved, and it is clearly found that it is also effective in preventing hair loss and promoting hair growth. Can be.

Claims (4)

청구항 1.

고추, 검정깨, 치자, 백급, 쪽풀을 혼합조성으로 하는 발모촉진용 조성물
Claim 1.

A composition for promoting hair growth comprising a mixture of red pepper, black sesame seeds, gardenia, white buckwheat and green grass
상기 1항에 있어서, 고추, 검정깨, 치자, 백급, 쪽풀을 아임계 추출법으로 추출한 것임을 특징으로 하는 발모촉진용 조성물
The composition for promoting hair growth according to claim 1, wherein red pepper, black sesame seeds, gardenia, white roe, and green grass are extracted by a subcritical extraction method.
상기 1항에 있어서, 고추, 검정깨, 치자, 백급, 쪽풀의 혼합조성은 전체 중량%에 대하여 각각 0.1중량%~5.0중량% : 1.0중량%~50.0중량% : 1.0중량%~40.0중량% : 1.0중량%~40.0중량% : 0.5중량%~10.0중량% 이고, 바람직하게는 1.0중량% : 40.0중량% : 30.0중량% : 25.0중량% : 4.0중량% 인 것임을 특징으로 하는 발모촉진용 조성물
The method according to claim 1, wherein the mixed composition of red pepper, black sesame, gardenia, white, and green grass is 0.1% to 5.0% by weight: 1.0% to 50.0% by weight: 1.0% to 40.0% by weight, based on the total weight: 1.0 wt% to 40.0 wt%: 0.5 wt% to 10.0 wt%, preferably 1.0 wt%: 40.0 wt%: 30.0 wt%: 25.0 wt%: 4.0% by weight of the composition for promoting hair growth
상기 1항에 있어서, 상기 혼합조성물이 헤어 샴푸, 헤어 토닉, 헤어 린스, 헤어 트리트먼트, 헤어 컨디셔너, 헤어 로션 등의 두발화장품으로 제형화되는 것을 특징으로 하는 발모촉진용 조성물
The composition for promoting hair growth according to claim 1, wherein the mixed composition is formulated as a hair cosmetic such as hair shampoo, hair tonic, hair rinse, hair treatment, hair conditioner, hair lotion, and the like.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104212626A (en) * 2014-08-15 2014-12-17 南阳泰瑞生物制品有限公司 Method for extracting gardenia oil by using subcritical fluid
CN109498502A (en) * 2018-11-28 2019-03-22 山东师范大学 A kind of antipruritic hair-cream of hair color protection and its preparation method and application

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104212626A (en) * 2014-08-15 2014-12-17 南阳泰瑞生物制品有限公司 Method for extracting gardenia oil by using subcritical fluid
CN104212626B (en) * 2014-08-15 2019-08-23 南阳泰瑞生物科技股份有限公司 A method of with subcritical fluid extraction cape jasmine oil
CN109498502A (en) * 2018-11-28 2019-03-22 山东师范大学 A kind of antipruritic hair-cream of hair color protection and its preparation method and application
CN109498502B (en) * 2018-11-28 2021-08-17 山东师范大学 Hair cream for protecting hair color and relieving itching as well as preparation method and application thereof

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