KR20120076170A - Preform for cosmetic composition and fermented cosmetic composition prepared therefrom - Google Patents

Abstract

PURPOSE: A cosmetic composition preform containing emulsifier-producing microorganisms is provided to form various and stable formulations. CONSTITUTION: A cosmetic composition preform contains 0.01-20 wt% of emulsifier-producing microoranisms or culture thereof; water as an aqueous phase; and fatty acid oil of 11-25 carbon atoms, oil, alkanol of 11-25 carbon atoms, or alkane of 11-25 carbon atoms. The microorganism includes Torulopsis bombicola, Torulopsis apicola, Torulopsis petrophilum, Candida Bombicola, Candida apicola, Candida petrophulum, or Thiobacillus thiooxidans. The microorganism culture is prepared by culturing the microorganisms in a medium containing saccharides, fatty acid of 11-25 carbon atoms, alkanole of 11-25 carbon atoms, or alkane of 11-25 carbon atoms.

Description

Cosmetic composition preform comprising an emulsifier-producing microorganism, and a fermentation cosmetic composition prepared therefrom {Preform for cosmetic composition and fermented cosmetic composition prepared therefrom}

The present invention relates to a cosmetic composition preform comprising an emulsifier-producing microorganism, and a fermentation cosmetic composition prepared therefrom, and more particularly, to a cosmetic composition preform and a cosmetic composition preform comprising a microorganism producing an emulsifier such as glycolipid or phospholipid. It relates to a fermentation cosmetic composition formed by fermentation.

Cosmetics are products formulated to make human skin, hair, nails, toenails, etc. beautiful or healthy, and generally cosmetics can be classified into basic cosmetics, color cosmetics, hair cosmetics, perfumes and other fragrances.

The manufacturing method of such cosmetics is largely divided into solubilization and emulsification. Solubilization is a component that is not easily dissolved in water, such as oil or fragrance, which is used in a lotion, and is dissolved in water by adding a surfactant. It refers to a system in which two liquids that do not mix with each other like oil are dispersed in one particle in one phase by using a surfactant.

On the other hand, in recent years, a variety of cosmetics that are beneficial to the body including yeasts and lactic acid bacteria, which are used in foods, are being developed as a social atmosphere that a good food to eat in accordance with the Well Being trend is created. In the manufacture of cosmetics, the yeasts and lactic acid bacteria described above are lyophilized or added in the form of a culture solution thereof. In addition, the yeasts, lactic acid bacteria, etc. are bacteria that play a beneficial role in the human body, and ferment sugars, proteins and the like to produce metabolites beneficial to the human body such as various organic acids and amino acids. , Moisturizes the skin, increases the stratum corneum turnover speed, improves wrinkles, and the like.

As described above, conventional cosmetics containing microorganisms utilize the microorganism itself or the microbial culture medium to obtain effects such as antioxidant, immune enhancement, skin moisturization, stratum corneum turnover rate, and wrinkle improvement. There was a limitation in the field of application.

The inventors of the present invention use the specific microorganisms to further stabilize the application of the microorganisms in cosmetics, to stabilize the formulation of the cosmetics, concomitantly antioxidation, enhance immunity, moisturize the skin, increase the stratum corneum turnover rate, improve wrinkles It has been found that active ingredients such as these can be obtained, and the present invention has been completed.

One object of the present invention is to provide a cosmetic composition preform comprising an emulsifier-producing microorganism for preparing cosmetic compositions of various formulations.

In addition, another object of the present invention to provide a fermentation cosmetic composition having a variety of stable formulations, including a topically produced microorganism.

In order to solve one object of the present invention, the present invention is an emulsifier-producing microorganism or a culture thereof; Water into the water phase; And one or more components selected from the group consisting of fatty acids having 11 to 25 carbon atoms, oils, alkanols having 11 to 25 carbon atoms, and alkanes having 11 to 25 carbon atoms, and wherein the emulsifier-producing microorganism is present. Is a torulopsis bombiola ( torulopsis) bombicola ), Torulopsis apicola ), Torulopsis petrophyllum petrophilum ), Candida Bombicola ), Candida apicola), Candida Petro plume (Candida petrophulum ) and Thiobacillus thiooxidans provides a cosmetic composition preform, characterized in that composed of one or more selected from the group consisting of.

In addition, in order to solve the other object of the present invention, the present invention provides a fermentation cosmetic composition formed by fermenting the cosmetic composition preform.

Since the cosmetic composition preform according to the present invention does not include a separate surfactant, an emulsifier is produced by fermentation of microorganisms, thereby forming a cosmetic composition of various and stable formulations. In addition, it can be useful in various fields such as cosmetics, pharmaceuticals and household goods as it can obtain active ingredients such as antioxidants, enhance immunity, moisturize skin, increase turnover rate of stratum corneum and improve wrinkles by fermentation of microorganisms. Is available.

One aspect of the present invention relates to a cosmetic composition preform for preparing cosmetic compositions of various formulations, wherein the cosmetic composition preform comprises an emulsifier-producing microorganism or a culture thereof; Water into the water phase; And one or more components selected from the group consisting of fatty acids having 11 to 25 carbon atoms, oils, alkanols having 11 to 25 carbon atoms, and alkanes having 11 to 25 carbon atoms in the oil phase.

The cosmetic composition preform according to the present invention includes an emulsifier-producing microorganism, wherein the emulsifier-producing microorganism is not limited in kind, for example, Torulopsis bombicola , Torulopsis apicola apicola ), Torulopsis petrophyllum petrophilum ), Candida Bombicola ), Candida apicola), Candida Petro plume (Candida petrophulum ) and Thiobacillus thiooxidans . Double Torulopsis Bombobia bombicola ), Torulopsis apicola ), Torulopsis petrophilum , Candida Bombicola ), Candida apicola , and Candida petrophulum produce Glycolipid as a metabolite, and Candida petrophulum produces Phospholipid as a metabolite. The glycolipid or phospholipid may be used as an emulsifier because it has a surface activity against hydrophobicity and hydrophilicity. In addition, the emulsifier composition preform according to the present invention preferably comprises a culture of an emulsifier-producing microorganism instead of an emulsifier-producing microorganism, wherein the culture of the emulsifier-producing microorganism is a culture of an emulsifier-producing microorganism in a medium, which includes microorganisms. Say. In this case, the medium of the emulsifier-producing microorganism is at least one selected from the group consisting of sugars, fatty acids having 11 to 25 carbon atoms, alkanol having 11 to 25 carbon atoms, and alkanes having 11 to 25 carbon atoms as carbon sources of the microorganism. Ingredients may be included, and further include inorganic salts. Examples of the saccharides contained in the medium include glucose and the like, stearic acid and the like as fatty acids, 2-hexadecanol and the like as alkanols, and alkanes as alkanes. Hexadecane and the like. The content of the emulsifier-producing microorganism or its culture is not particularly limited, for example, 0.001 to 50% by weight, preferably 0.01 to 20% by weight, based on the total weight of the cosmetic composition preform.

The cosmetic composition preform according to the present invention includes water as an aqueous phase, and as an oil phase, a fatty acid having 11 to 25 carbon atoms, an oil, an alkanol having 11 to 25 carbon atoms, and an alkanne having 11 to 25 carbon atoms. One or more components selected from the group consisting of: At this time, water provides a basic environment for the emulsifier-producing microorganism to survive, and the oily component serves as a carbon source of the emulsifier-producing microorganism. In addition, the cosmetic composition preform according to the present invention may preferably further comprise a saccharide as a carbon source of the emulsifier-producing microorganism. Hereinafter, the carbon source of the emulsifier-producing microorganism included in the cosmetic composition preform according to the present invention will be described in detail.

Fatty acids used as carbon sources for emulsifier-forming microorganisms include, for example, lauric acid, myristic acid, palmitic acid, stearic acid, and behenic acid. ), Oleic acid, linoleic acid, linolenic acid, linolenic acid, eicosapentaenoic acid (EPA), docosahexaenoic acid (Docosahexaenoic acid (DHA)).

Oils used as carbon sources for emulsifying microorganisms include, for example, avocado oil, camellia oil, turtle oil, macadamia nut oil, corn oil, mink oil, olive oil, canola oil, and rapeseed seeds. Rapeseed oil, sunflower oil, egg yolk oil, sesame oil, puddle oil, wheat germ oil, baby camellia oil, castor oil, flaxseed oil, safflower oil, cottonseed oil, perilla oil, soybean oil , Peanut oil, green tea oil, non-tree oil, chaff oil, paulownia oil, Japanese paulownia oil, jojoba oil, embryo oil, triglycerine, cacao, palm oil, hardened palm oil, palm oil, palm kernel oil, wax Nuclear oil, hardened oil, wax, hardened castor oil, etc. are mentioned.

Alkanols used as carbon sources of emulsifier-producing microorganisms include, for example, 1-undecanol, 1-dodecanol (1-dodecanol or Lauryl alcohol), 1-tridecanol, 1 Tetradecanol, 1-pentadecanol, 1-hexadecanol, 1-hexadecanol or cetyl alcohol, 1-heptadecanol, 1-octadecane Ol (1-octadecanol or stearyl alcohol), 1-nonadecanol, 1-eicosanol, 1-heneicosanol, 1-docosanol (1- docosanol or behenyl alcohol), Cetearyl alcohol, or secondary alcohols thereof (eg, 2-Dodecanol, 2-Tetradecanol, 2-Hexadecanol, etc.).

Alkanes used as carbon sources for emulsifier-producing microorganisms include Undecane, Dodecane, Tridecane, Tridecane, Pentadecane, Hexadecane, Hepdecane, Octadecan Octadecane), Icosane (Icosane or Eicosane), and the like.

Monosaccharides, oligosaccharides, polysaccharides, etc. may be used as the saccharide used as the carbon source of the emulsifier-producing microorganism, and as the monosaccharides, for example, D-glucose, D-talose, D-bushcoose, D-galactose, and D-fructo Oss, L-galactose, L-mannose, D-tagatose, and the like, and oligosaccharides include, for example, sucrose, lactose, trehalose, and the like, and polysaccharides, for example, starch, galactan, arabic gum. , Xanthan gum, guar gum, dextran, and locust bean gum.

The cosmetic composition preform according to the invention may preferably further comprise a thickener to maximize the stability and emulsion stability of the formulation. Usable thickeners include, for example, gum arabic, carrageenan, karaya gum, tragacanth gum, carob gum, queen's seed (mamelo), casein, dextrin, gelatin, sodium pectinate, sodium arachite, Methyl cellulose, ethyl cellulose, carboxymethyl cellulose, hydroxyethyl cellulose

Loose, hydroxypropyl cellulose, polyvinyl alcohol, polyvinylmethyl ether, polyvinylpyrrolidone, sodium polyacrylate, carboxyvinyl polymer, locust bean gum, guar gum, tamarind gum, dialkyldimethyl Ammonium sulfate cellulose, xanthan gum, magnesium aluminum silicate, bentite, hectorite, silicate AlMg (non-gum), laponite, silicic anhydride and the like.

In addition, the cosmetic composition according to the present invention may further include waxes when the formulation is semi-solid. Available waxes include beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, pewter, spermatozoon, montan wax, rice bran wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugar cane wax, lanolin fatty acid iso Propyl, hexyl laurate, reduced lanolin, jojoba wax, hard lanolin, shellac wax, POE lanolin alcohol ether, POE lanolin alcohol acetate, POE cholesterol ether, lanolin fatty acid polyethylene glycol, POE hydrogenated lanolin alcohol ether, and the like.

In addition, the cosmetic composition according to the present invention may further include one or more active ingredients selected from the group consisting of antioxidants, whitening agents, anti-wrinkle agents, skin regenerating agents, sunscreens, and moisturizing agents. Antioxidants include, for example, vitamins, tocopherols, dibutylhydroxytoluene, butylhydroxyanisole, gallic acid esters, and the like, and whitening agents include, for example, pancreatic extract, arbutin, and the like. Polyethylene glycol, propylene glycol, glycerin, 1,3-butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucotin sulfate, caronic acid, atherocollagen, cholesteryl-12-hydroxystearate, Sodium lactate, bile salts, dl-pyrrolidonecarboxylates, short-chain soluble collagen, diglycerin (EO) PO adducts, Rosa roxburghii extracts, yarrow extracts, maryrod extracts, etc. Various known active ingredients can be used without any known.

In addition, the cosmetic composition preform according to the present invention may preferably contain a trace level which does not contain a preservative or does not irritate the skin, and preferably it does not contain a preservative. Preservatives in the present invention, as well as synthetic preservatives such as parabens ((methyl parabens, ethyl parabens, propyl parabens, butyl parabens, etc.), imidazolidinyl urea, diazolidinyl urea, phenoxyethanol, benzoic acid, as well as sorbic acid and its It is a concept including all salts, antimicrobial or antiseptic polyols, natural plant extracts, natural animal extracts, bacteriocins produced by microorganisms such as lactic acid bacteria, etc. The cosmetic composition preform according to the present invention does not contain a preservative or a trace amount. When included in the level, the fermentation cosmetic composition formed by fermenting the cosmetic composition preform is preferably for refrigeration distribution stored at 0 ~ 10 ° C. When the fermentation cosmetic composition according to the invention is an antiseptic composition, such as skin irritation Concerns are blocked in advance and the fermentation cosmetic composition according to the invention is refrigerated under When distributed, there is an advantage that little modification of active ingredients such as antioxidants, whitening agents, anti-wrinkle agents, skin regenerating agents, and sunscreens occurs.

In addition, the cosmetic composition preform according to the present invention may further include a lower alcohol, a chelating agent, a pigment, a perfume, and the like as necessary.

Another aspect of the present invention relates to a fermentation cosmetic composition, wherein the cosmetic composition according to the present invention is formed by fermenting the aforementioned cosmetic composition preform. When the cosmetic composition preform is fermented, the emulsifier-producing microorganism releases a surface active material such as phospholipid or glycolipid, that is, an emulsifier as a metabolite, and the oil phase is completely solubilized in the water phase or the oil phase and the water phase are completely emulsified by the emulsifier. It is possible to achieve the formulation. The final fermentation cosmetic composition may have any of the formulations selected from liquid, semi-solid, or solid, for example semi-solid, wax, balm, such as liquid, cream or gel, such as lotion, essence, lotion, etc. Solid shapes such as the like and the like are possible.

Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are only to illustrate the content of the present invention and do not limit the protection scope of the present invention.

1. Preparation of Microbial Cultures

Production Example 1

The pH of the medium having the composition of Table 1 was adjusted to 5.6, inoculated with Thiobacillus thiooxidans , and then incubated at a temperature of 25 ° C. for about 450 hours to incubate Thiobacillus thiooxidans . Water was prepared.

Raw material Composition ratio (% by weight) Glucose 10 Hexadecane 24 Yeast extract 0.1 KH ₂ PO ₄ 0.1 K ₂ HPO ₄ -3H ₂ O 0.016 MgSO ₄ ? 7H ₂ O 0.07 NaCl 0.05 Ca (NO ₃ ) ₂ ˜4H ₂ O 0.04 (NH ₄ ) ₂ SO ₄ 0.1 water Balance

Production Example 2

Adjusting the pH of the culture medium having a composition shown in Table 2 to 5.6 and where SAT rulrop sheath spring rain coke by culturing for about 168-210 hours at a temperature of 25 ~ 30 ℃ and then inoculated (Torulopsis bombicola) SAT rulrop the sheath spring rain coke (Torulopsis culture of bombicola ) was prepared.

Raw material Composition ratio (% by weight) Glucose 10 2-hexadecanol 24 Yeast extract 0.1 KH ₂ PO ₄ 0.1 K ₂ HPO ₄ -3H ₂ O 0.016 MgSO ₄ ? 7H ₂ O 0.07 NaCl 0.05 CaCl _2? 2H ₂ O 0.027 NaNO ₃ ˜3H ₂ O 0.5 (NH ₄ ) Cl 0.15 water Balance

2. Cosmetics  Composition Preform  And fermentation Cosmetics  Preparation of the composition

Example 1 Preparation of Lotion Preforms and Fermented Lotion

Table 3 shows the raw material and its content of the lotion preform. After mixing the raw materials corresponding to the raw material numbers 1 to 5 and 7 of Table 3 and sterilized for 10 minutes at 95 ℃ and cooled to 40 ~ 45 ℃. At this time, the mixture was in a state in which the oil phase and the water phase were separated. Thereafter, a culture of Thiobacillus thiooxidans prepared in Preparation Example 1 corresponding to Raw Material No. 6 was added in an amount of 10.0 wt% to prepare a skin lotion preform.

Fermentation lotion was prepared by fermenting the lotion preform at 40-45 ° C. for 5 hours. Fermented lotion showed a liquid formulation in which the oil phase was completely solubilized in the aqueous phase and stabilized. The fermentation lotion was sterilized at 130 ° C. for 2 seconds and immediately cooled to 5 ° C. to prepare a final product of microbial fermentation lotion.

Raw material number Raw material name Raw material composition ratio (wt%) One Glycerin 5.0 2 Xanthan gum 0.01 3 Olive oil 20.0 4 Perfume 0.01 5 Chinese herbal medicine extract 1.0 6 Culture of Thiobacillus thiooxidans of Preparation Example 1 10.0 7 Purified water Balance

Example 2 Preparation of Lotion Preforms and Fermentation Lotion

Table 4 shows the raw materials of the lotion preforms and their contents. After mixing the raw materials corresponding to the raw material numbers 1 to 5 and 7 to 8 of Table 4 and sterilized for 10 minutes at 95 ℃ and cooled to 40 ~ 45 ℃. At this time, the mixture was in a state in which the oil phase and the water phase were separated.

After toluropsis Bomb Vicola prepared in Preparation Example 2 corresponding to the raw material number 6 ( Toroulopsis A lotion preform was prepared by adding a culture of bombicola ) to an amount of 10.0 wt%.

The lotion preform was fermented at 40-45 ° C. for 6 hours to prepare a fermentation lotion. The fermentation lotion showed a liquid formulation in which the oil and water phases were fully emulsified and stabilized. The fermentation lotion was sterilized at 130 ° C. for 2 seconds and immediately cooled to 5 ° C. to prepare a final product microbial fermentation lotion.

Raw material number Raw material name Raw material composition ratio (wt%) One Cetearyl alcohol 2.0 2 Stearic acid 10.0 3 Olive oil 5.0 4 2-dodecanol 5.0 5 Glycerin 5.0 6 Culture of Torulopsis bombicola of Preparation Example 2 10.0 7 Perfume 0.1 8 Purified water Balance

Example 3 Preparation of Cream Preforms and Fermented Creams

Table 5 shows the raw materials of the cream preforms and their contents. After mixing the raw materials corresponding to the raw material numbers 1 to 7 and 9 to 10 of Table 5 and sterilized for 10 minutes at 95 ℃ and cooled to 40 ~ 45 ℃. At this time, the mixture was in a state in which the oil phase and the water phase were separated.

Subsequently, tolulopsis bombbiola ( torulopsis) prepared in Preparation Example 2, which corresponds to raw material number 8. The culture of bombicola ) was added to the content of 10.0% by weight to prepare a cream preform.

Fermented cream was prepared by fermenting the cream preform at 40-45 ° C. for 6 hours. The fermented cream exhibited a semisolid formulation in which the oil and water phases were fully emulsified and stabilized. The fermentation cream was sterilized at 130 ° C. for 2 seconds and immediately cooled to 5 ° C. to prepare a final product microbial fermentation cream.

Raw material number Raw material name Raw material composition ratio (wt%) One Cetearyl alcohol 3.0 2 Beewax 1.0 3 Stearic acid 10.0 4 Olive oil 5.0 5 2-dodecanol 5.0 6 Glycerin 5.0 7 Dipropylene glycol 5.0 8 Culture of Torulopsis bombicola of Preparation Example 2 10.0 9 Perfume 0.1 10 Purified water Balance

Although the present invention has been described through the above embodiments as described above, the present invention is not necessarily limited thereto, and various modifications can be made without departing from the scope and spirit of the present invention. In addition, many modifications may be made to adapt a particular situation and material to the teachings of the invention without departing from the essential scope thereof. Therefore, the protection scope of the present invention should not be construed as limited to the specific embodiments disclosed as the best mode contemplated for carrying out the invention, but including all embodiments falling within the scope of the claims appended hereto.

Claims (10)

Emulsifier producing microorganisms or cultures thereof;
Water into the water phase; And
At least one component selected from the group consisting of fatty acids having 11 to 25 carbon atoms, oils, alkanols having 11 to 25 carbon atoms, and alkanes having 11 to 25 carbon atoms,
The emulsifier-producing microorganism is Torulopsis bombicola ), Torulopsis apicola ), Torulopsis petrophilum , Candida Bombicola), Candida Bahia Cola (Candida apicola), Candida Petro plume (Candida petrophulum ) and Thiobacillus thiooxidans ( Thiobacillus thiooxidans ) A cosmetic composition preform, characterized in that consisting of one or more selected from the group consisting of.
The cosmetic composition preform according to claim 1, wherein the content of the emulsifier-producing microorganism or its culture is 0.01 to 20% by weight based on the total weight of the cosmetic composition preform.
The method of claim 1, wherein the culture of the emulsifier-producing microorganism is a culture of the emulsifier-producing microorganism in a medium,
The medium comprises at least one component selected from the group consisting of sugars, fatty acids having 11 to 25 carbon atoms, alkanols having 11 to 25 carbon atoms, and alkanes having 11 to 25 carbon atoms as a carbon source. Cosmetic composition preform.
The cosmetic composition preform according to claim 1, further comprising a saccharide as a carbon source of the emulsifier-producing microorganism.
The cosmetic composition preform according to claim 1, further comprising a thickener.
The cosmetic composition preform of claim 1, further comprising at least one active ingredient selected from the group consisting of antioxidants, whitening agents, anti-wrinkle agents, skin rejuvenating agents, sunscreens, and moisturizing agents.
The cosmetic composition preform according to claim 1, wherein the cosmetic composition preform does not contain a preservative.
Fermentation cosmetic composition formed by fermenting the cosmetic composition preform of any one of Claims 1-7.
10. The fermentation cosmetic composition of claim 8, wherein the cosmetic composition has any one of liquid, semi-solid, and solid dosage forms.
According to claim 8, wherein the cosmetic composition is a fermentation cosmetic composition, characterized in that the refrigeration distribution cosmetic composition stored at 0 ~ 10 ℃.