KR20120061053A - 유도 만능 줄기(iPS) 세포 또는 조직 특이적 세포를 생성하기 위한 신규한 단백질 전달 시스템 - Google Patents
유도 만능 줄기(iPS) 세포 또는 조직 특이적 세포를 생성하기 위한 신규한 단백질 전달 시스템 Download PDFInfo
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- KR20120061053A KR20120061053A KR1020127006735A KR20127006735A KR20120061053A KR 20120061053 A KR20120061053 A KR 20120061053A KR 1020127006735 A KR1020127006735 A KR 1020127006735A KR 20127006735 A KR20127006735 A KR 20127006735A KR 20120061053 A KR20120061053 A KR 20120061053A
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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| TWI815599B (zh) | 2011-04-22 | 2023-09-11 | 美商惠氏有限責任公司 | 與難養芽胞梭菌(Clostridium difficile)之突變毒素有關之組成物及彼之方法 |
| ES2653249T3 (es) * | 2011-09-29 | 2018-02-06 | Cellsnap, Llc | Composiciones y métodos para ensayos de toxigenicidad |
| WO2013084071A2 (en) | 2011-12-08 | 2013-06-13 | Novartis Ag | Clostridium difficile toxin-based vaccine |
| AR089797A1 (es) * | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
| US8986704B2 (en) | 2012-07-06 | 2015-03-24 | Valneva Austria Gmbh | Mutant fragments of OspA and methods and uses relating thereto |
| BR122016023101B1 (pt) | 2012-10-21 | 2022-03-22 | Pfizer Inc | Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile |
| US9493518B2 (en) * | 2013-03-14 | 2016-11-15 | National Health Research Institutes | Compositions and methods for treating clostridium difficile-associated diseases |
| AU2014301116B2 (en) | 2013-06-28 | 2019-11-14 | Merz Pharma Gmbh & Co. Kgaa | Means and methods for the determination of the biological activity of Neurotoxin polypeptides in cells |
| KR20170020431A (ko) | 2014-06-27 | 2017-02-22 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 변이형 헤마글루티닌 복합체 단백질, 및 그것을 사용한 다능성을 갖는 간세포의 배양 방법 |
| US10633643B2 (en) | 2015-05-15 | 2020-04-28 | Board Of Regents Of The University Of Nebraska | Engineered Clostridium botulinum toxin adapted to deliver molecules into selected cells |
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| WO2020055915A1 (en) | 2018-09-10 | 2020-03-19 | Kavazanjian Edward | Biocementation systems and methods |
| CA3174599A1 (en) * | 2020-04-09 | 2021-10-14 | Robert Schlegl | Improvements in vaccine formulations for medical use |
| EP4132950A1 (en) | 2020-04-09 | 2023-02-15 | Valneva Austria GmbH | Compositions comprising three ospa fusion proteins for medical use |
| WO2021255690A2 (en) | 2020-06-19 | 2021-12-23 | Pfizer Inc. | Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof |
| CN113563428B (zh) * | 2021-06-22 | 2022-08-02 | 呈诺再生医学科技(珠海横琴新区)有限公司 | 特定空间结构多肽及其在制备iPSC中的应用 |
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| US20090203141A1 (en) | 2003-05-15 | 2009-08-13 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant RNA agents |
| US20050147593A1 (en) | 2003-05-22 | 2005-07-07 | Medimmune, Inc. | EphA2, EphA4 and LMW-PTP and methods of treatment of hyperproliferative cell disorders |
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| TW200640493A (en) | 2005-02-16 | 2006-12-01 | Insert Therapeutics Inc | Cyclodextrin-based polymers for therapeutics delivery |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| CN105861443A (zh) | 2007-04-07 | 2016-08-17 | 怀特黑德生物医学研究所 | 体细胞重编程 |
| EP2164951A2 (en) * | 2007-05-30 | 2010-03-24 | The General Hospital Corporation | Methods of generating pluripotent cells from somatic cells |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| WO2009009441A2 (en) | 2007-07-06 | 2009-01-15 | Cedars-Sinai Medical Center | Self-assembling complex for targeting chemical agents to cells |
| WO2009032456A2 (en) | 2007-08-01 | 2009-03-12 | Primegen Biotech Llc | Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state |
| WO2009073523A2 (en) | 2007-11-29 | 2009-06-11 | Children's Hospital Of Orange County | De-differentiation of human cells |
| EP2224940A1 (en) | 2007-11-30 | 2010-09-08 | Cytomatrix PTY LTD | Methods of inducing pluripotency involving oct4 protein |
| US20110190729A1 (en) | 2007-11-30 | 2011-08-04 | Cytomatrix Pty Ltd | Methods of inducing pluripotency involving sox2 protein |
| WO2009102983A2 (en) | 2008-02-15 | 2009-08-20 | President And Fellows Of Harvard College | Efficient induction of pluripotent stem cells using small molecule compounds |
| CN101550406B (zh) | 2008-04-03 | 2016-02-10 | 北京大学 | 制备多潜能干细胞的方法,试剂盒及用途 |
| CA2695590C (en) | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| EP2307539B1 (en) | 2008-07-30 | 2014-11-19 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| CN102272290B (zh) | 2008-10-09 | 2018-08-14 | 米纳瓦生物技术公司 | 用于在细胞中诱导多能性的方法 |
| JP2012507258A (ja) | 2008-10-30 | 2012-03-29 | 国立大学法人京都大学 | 人工多能性幹細胞の作製方法 |
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