KR20110027696A - 세포를 보호유지하고 재순환시키는 방법 및 장치 - Google Patents

세포를 보호유지하고 재순환시키는 방법 및 장치 Download PDF

Info

Publication number
KR20110027696A
KR20110027696A KR1020107028446A KR20107028446A KR20110027696A KR 20110027696 A KR20110027696 A KR 20110027696A KR 1020107028446 A KR1020107028446 A KR 1020107028446A KR 20107028446 A KR20107028446 A KR 20107028446A KR 20110027696 A KR20110027696 A KR 20110027696A
Authority
KR
South Korea
Prior art keywords
channel
cells
channels
hollow cylinder
bioreactor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020107028446A
Other languages
English (en)
Korean (ko)
Inventor
죄르크 카우링
브죄른 프람
마르크 젠네
헬무트 브로드
슈테판 키르크너
아른트 브라운
Original Assignee
바이엘 테크놀로지 서비시즈 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바이엘 테크놀로지 서비시즈 게엠베하 filed Critical 바이엘 테크놀로지 서비시즈 게엠베하
Publication of KR20110027696A publication Critical patent/KR20110027696A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/06—Tubular
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/22—Settling tanks; Sedimentation by gravity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020107028446A 2008-06-20 2009-06-10 세포를 보호유지하고 재순환시키는 방법 및 장치 Withdrawn KR20110027696A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008029307.5 2008-06-20
DE102008029307A DE102008029307A1 (de) 2008-06-20 2008-06-20 Verfahren und Vorrichtung zur Rückhaltung und Rückführung von Zellen

Publications (1)

Publication Number Publication Date
KR20110027696A true KR20110027696A (ko) 2011-03-16

Family

ID=41334928

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107028446A Withdrawn KR20110027696A (ko) 2008-06-20 2009-06-10 세포를 보호유지하고 재순환시키는 방법 및 장치

Country Status (10)

Country Link
US (1) US20110097800A1 (enExample)
EP (1) EP2304017A2 (enExample)
JP (1) JP2011529331A (enExample)
KR (1) KR20110027696A (enExample)
CN (1) CN102239244B (enExample)
AU (1) AU2009259664A1 (enExample)
CA (1) CA2728453A1 (enExample)
DE (1) DE102008029307A1 (enExample)
IL (1) IL209232A0 (enExample)
WO (1) WO2009152990A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140135159A (ko) * 2012-02-20 2014-11-25 바이엘 테크놀로지 서비시즈 게엠베하 세포를 유지하고 재순환시키기 위한 단방향 분리기

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115185A1 (en) * 2009-04-03 2010-10-07 Xcellerex, Inc. Tissue and organ graft bioreactor and method of operation
ES2890412T3 (es) * 2011-01-17 2022-01-19 Hoffmann La Roche Aparato de separación
EP2864469A4 (en) * 2012-06-21 2016-05-18 Neostem Oncology Llc BIOREACTOR CARTRIDGE AND SYSTEM
JP2015077119A (ja) * 2013-10-15 2015-04-23 カンウォン ナショナル ユニバーシティ， ユニバーシティ−インダストリー コーペレーション ファンデーション アクチノバシラススクシノゲネスを用いたコハク酸連続生産工程
US10596492B2 (en) 2014-07-09 2020-03-24 Sudhin Biopharma Particle settling devices
WO2016089874A1 (en) * 2014-12-01 2016-06-09 Sudhin Biopharma Particle settling device with annular ramps
AU2019257236B2 (en) 2018-04-18 2022-09-01 Sudhin Biopharma Particle settling devices
CN115461156A (zh) 2020-03-19 2022-12-09 苏德新生物制药公司 颗粒沉降装置
WO2021199529A1 (ja) * 2020-03-31 2021-10-07 昭和電工マテリアルズ株式会社 細胞培養装置及び培養方法
DE102020118668A1 (de) * 2020-07-15 2022-01-20 Hochschule Anhalt (FH) , Körperschaft des öffentlichen Rechts Fermentationsverfahren und Bioreaktor zur Durchführung von anaeroben, aeroben und mikro-aerophilen Fermentationen umfassend einen Airlift-Schachtüberfall
TWI751073B (zh) * 2021-04-15 2021-12-21 蘇碩彥 交叉複合式傾斜管之製造方法與生產線
WO2025027938A1 (ja) * 2023-07-31 2025-02-06 エイブル株式会社 培養装置及び細胞分離方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990006991A1 (en) 1984-08-03 1990-06-28 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Process and apparatus for the bubble-free gassing of liquids, especially of culture media for propagating tissue cultures
US4814278A (en) * 1985-02-05 1989-03-21 Teijin Limited Culture apparatus and method
GB8515636D0 (en) 1985-06-20 1985-07-24 Celltech Ltd Fermenter
DE3535183A1 (de) 1985-10-02 1987-04-16 Biotechnolog Forschung Gmbh Vorrichtung und verfahren zur blasenfreien begasung von fluessigkeiten, insbesondere von kulturmedien zur vermehrung von gewebekulturen
US5320963A (en) * 1992-11-25 1994-06-14 National Research Council Of Canada Bioreactor for the perfusion culture of cells
GB9309429D0 (en) 1993-05-07 1993-06-23 Bioscot Ltd Fermenter accessory
DE60238863D1 (de) 2001-08-31 2011-02-17 Bayer Schering Pharma Ag Vorrichtung und verfahren zur fermentation in hohen zelldichten
CN1286966C (zh) * 2003-12-10 2006-11-29 上海伯瑞生物技术发展有限公司 造血细胞连续灌注悬浮培养过程细胞沉降截留装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140135159A (ko) * 2012-02-20 2014-11-25 바이엘 테크놀로지 서비시즈 게엠베하 세포를 유지하고 재순환시키기 위한 단방향 분리기

Also Published As

Publication number Publication date
CN102239244A (zh) 2011-11-09
CN102239244B (zh) 2014-10-29
US20110097800A1 (en) 2011-04-28
DE102008029307A1 (de) 2009-12-24
CA2728453A1 (en) 2009-12-23
AU2009259664A1 (en) 2009-12-23
IL209232A0 (en) 2011-01-31
EP2304017A2 (de) 2011-04-06
JP2011529331A (ja) 2011-12-08
WO2009152990A3 (de) 2011-11-24
WO2009152990A2 (de) 2009-12-23

Similar Documents

Publication Publication Date Title
KR20110027696A (ko) 세포를 보호유지하고 재순환시키는 방법 및 장치
KR100909316B1 (ko) 고세포밀도 발효를 수행하기 위한 유닛 및 방법
JP6239532B2 (ja) 細胞を保持し再循環させるための一方向分離器
JP3328287B2 (ja) 細胞培養に使用される粒子沈降タンク
AU2002333739A1 (en) A unit and a process for carrying out high cell density fermentation
US9101857B2 (en) Gas scrubbed perfusion filter
EP2785654B1 (en) Biological treatment and installation with air-lift and biofilm carriers
EP0416061A4 (en) Apparatus for oxygenating culture medium
CN1384874A (zh) 培养细胞的方法,膜组件,膜组件的应用和培养细胞的反应系统
TW202327712A (zh) 生物反應器內的粒子沉降裝置
JP2025540055A (ja) かん流バイオリアクタ内で培養培地を酸素化するためのシステム及び方法
CN120584177A (zh) 泡沫破坏装置及泡沫破坏方法
HK1073668B (en) A unit and a process for carrying out high cell density fermentation
HK1050546A (en) Method for cultivating cells, a membrane module, utilization of a membrane module and reaction system for cultivation of said cells

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20101217

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid