KR20110025168A - 약학적 조성물 - Google Patents
약학적 조성물 Download PDFInfo
- Publication number
- KR20110025168A KR20110025168A KR1020107024775A KR20107024775A KR20110025168A KR 20110025168 A KR20110025168 A KR 20110025168A KR 1020107024775 A KR1020107024775 A KR 1020107024775A KR 20107024775 A KR20107024775 A KR 20107024775A KR 20110025168 A KR20110025168 A KR 20110025168A
- Authority
- KR
- South Korea
- Prior art keywords
- modulator
- complex
- enzyme
- pdh
- cells
- Prior art date
Links
- 0 *C1SNSCC1 Chemical compound *C1SNSCC1 0.000 description 1
- CYORVQAKGJJARR-UHFFFAOYSA-N CCSC(CCCCC(O)=O)CCSc1ccccc1 Chemical compound CCSC(CCCCC(O)=O)CCSc1ccccc1 CYORVQAKGJJARR-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2008/004410 WO2009123597A1 (en) | 2008-04-04 | 2008-04-04 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20110025168A true KR20110025168A (ko) | 2011-03-09 |
Family
ID=41135840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020107024775A KR20110025168A (ko) | 2008-04-04 | 2008-04-04 | 약학적 조성물 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP2268278A4 (es) |
JP (1) | JP2011516473A (es) |
KR (1) | KR20110025168A (es) |
CN (1) | CN102056605A (es) |
AU (1) | AU2008354009A1 (es) |
BR (1) | BRPI0821894A2 (es) |
CA (1) | CA2720396A1 (es) |
IL (1) | IL208387A0 (es) |
MX (1) | MX2010010867A (es) |
WO (1) | WO2009123597A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX343847B (es) | 2010-07-08 | 2016-11-24 | Wrigley W M Jun Co | Goma de mascar que contiene una base de goma de matriz de gelatina reticulada. |
US9421234B2 (en) * | 2011-05-20 | 2016-08-23 | Nutramax Laboratories, Inc. | Orally administrable compositions comprising avocado/soybean unsaponifiables and lipoic acid and methods of administration |
CA2863600A1 (en) * | 2012-02-16 | 2013-08-22 | The Penn State Research Foundation | Modulators of acyl-coa lysocardiolipin acyltransferase 1 ( alcat1) and uses thereof |
CN105142643B (zh) * | 2012-12-19 | 2021-09-03 | 基石医药公司 | 药物化合物 |
AU2014398232B2 (en) | 2014-06-19 | 2019-11-28 | Rafael Pharmaceuticals, Inc. | Pharmaceutical compounds |
WO2015195071A1 (en) | 2014-06-19 | 2015-12-23 | Robert Shorr | Pharmaceutical compounds |
CN110590624B (zh) * | 2019-09-26 | 2021-02-26 | 苏州富士莱医药股份有限公司 | 一种硫辛酸衍生物8-(乙基二硫基)-6-(苯基二硫基)辛酸的制备方法 |
WO2023012305A1 (en) * | 2021-08-04 | 2023-02-09 | Cytacoat Ab | Disulfide compounds as medicaments |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2853497A (en) * | 1953-12-04 | 1958-09-23 | Merck & Co Inc | 6, 8-bis (hydrocarbon substituted mercapto) 5-hydroxycaprylic acids and delta-lactones thereof |
US2789991A (en) * | 1954-05-20 | 1957-04-23 | American Cyanamid Co | Substituted disulfones |
JPS61198148A (ja) * | 1985-01-29 | 1986-09-02 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
GB9618934D0 (en) * | 1996-09-11 | 1996-10-23 | Univ London | Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity |
DK1624060T3 (da) * | 1998-03-20 | 2012-04-10 | Commw Scient Ind Res Org | Kontrol af genekspression |
FR2777001B1 (fr) * | 1998-04-01 | 2000-06-09 | Cird Galderma | Derives de l'acide 6,8-dimercaptooctanoique substitues en 6-s et/ou en 8-s par le radical (3-methylthiopropanoyl) et compositions pharmaceutiques destinees au traitement des tumeurs cancereuses |
US6331559B1 (en) * | 1998-10-26 | 2001-12-18 | The Research Foundation Of State University Of New York At Stony Brook | Lipoic acid derivatives and their use in treatment of disease |
DE19904794A1 (de) * | 1999-02-05 | 2000-08-10 | Biotechnolog Forschung Gmbh | Verfahren zur Verbesserung des Primärstoffwechsels von Säugerzelllinien |
US6284786B1 (en) * | 1999-02-16 | 2001-09-04 | The Center For The Improvement Of Human Functioning, Int'l., Inc. | Treatment of cancer using lipoic acid in combination with ascorbic acid |
AR042572A1 (es) * | 1999-04-02 | 2005-06-29 | Sod Conseils Rech Applic | Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos |
IT1312060B1 (it) * | 1999-04-09 | 2002-04-04 | Antibioticos Spa | Uso dell'acido alfa lipoico nel trattamento antimetastatico. |
US7108977B2 (en) * | 2000-05-19 | 2006-09-19 | Hoffmann-La Roche Inc. | Process for determining the tumoricidal potential of a sample the use of a nucleic acid which is downregulated in human tumor cells |
WO2006119355A2 (en) * | 2005-05-03 | 2006-11-09 | Albert Einstein College Of Medicine Of Yeshiva University | Mammalian hypothalamic nutrient modulation of glucose metabolism |
US20070077583A1 (en) * | 2005-09-21 | 2007-04-05 | Aurelium Biopharma, Inc. | Alpha enolase-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance |
US20070212360A1 (en) * | 2006-01-17 | 2007-09-13 | Denko Nicholas C | Modulation of mitochondrial oxygen consumption for therapeutic purposes |
JP5412423B2 (ja) * | 2007-04-18 | 2014-02-12 | コーナーストーン ファーマシューティカルズ,インコーポレーテッド | リポ酸誘導体 |
AU2008242827B2 (en) * | 2007-04-18 | 2014-06-05 | Cornerstone Pharmaceuticals, Inc. | Pharmaceutical formulations containing lipoic acid derivatives |
BRPI0821176A2 (pt) * | 2008-03-04 | 2015-10-06 | Robert Rodriguez | modulador do estado de fosforilação de pelo menos um complexo de enzimas, método para modular o complexo de pdh em um paciente que apresenta uma doença, condição, ou síndrome e método pra diagnosticar e predizer benefício em um paciente que apresenta sintomas de uma doença, condição, ou síndrome causada por uma alteração da estrutura e/ou da atividade do complexo de pdh |
-
2008
- 2008-04-04 CA CA2720396A patent/CA2720396A1/en not_active Abandoned
- 2008-04-04 WO PCT/US2008/004410 patent/WO2009123597A1/en active Application Filing
- 2008-04-04 KR KR1020107024775A patent/KR20110025168A/ko not_active Application Discontinuation
- 2008-04-04 AU AU2008354009A patent/AU2008354009A1/en not_active Abandoned
- 2008-04-04 JP JP2011502908A patent/JP2011516473A/ja active Pending
- 2008-04-04 CN CN2008801296335A patent/CN102056605A/zh active Pending
- 2008-04-04 MX MX2010010867A patent/MX2010010867A/es not_active Application Discontinuation
- 2008-04-04 EP EP08742562A patent/EP2268278A4/en not_active Withdrawn
- 2008-04-04 BR BRPI0821894-3A patent/BRPI0821894A2/pt not_active IP Right Cessation
-
2010
- 2010-10-03 IL IL208387A patent/IL208387A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2268278A4 (en) | 2011-11-09 |
BRPI0821894A2 (pt) | 2015-07-21 |
AU2008354009A1 (en) | 2009-10-08 |
WO2009123597A1 (en) | 2009-10-08 |
EP2268278A1 (en) | 2011-01-05 |
JP2011516473A (ja) | 2011-05-26 |
CN102056605A (zh) | 2011-05-11 |
MX2010010867A (es) | 2011-05-25 |
CA2720396A1 (en) | 2009-10-08 |
IL208387A0 (en) | 2010-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E601 | Decision to refuse application |