KR20100040427A - Curing method using autotooth and treating method of autotooth - Google Patents

Curing method using autotooth and treating method of autotooth Download PDF

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Publication number
KR20100040427A
KR20100040427A KR1020080099523A KR20080099523A KR20100040427A KR 20100040427 A KR20100040427 A KR 20100040427A KR 1020080099523 A KR1020080099523 A KR 1020080099523A KR 20080099523 A KR20080099523 A KR 20080099523A KR 20100040427 A KR20100040427 A KR 20100040427A
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KR
South Korea
Prior art keywords
tooth
degreasing
washing
teeth
bone
Prior art date
Application number
KR1020080099523A
Other languages
Korean (ko)
Inventor
엄인승
Original Assignee
주식회사 코리아티슈뱅크
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Priority to KR1020080099523A priority Critical patent/KR20100040427A/en
Priority to PCT/KR2009/004490 priority patent/WO2010041814A2/en
Publication of KR20100040427A publication Critical patent/KR20100040427A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C13/00—Dental prostheses; Making same
    • A61C13/0003—Making bridge-work, inlays, implants or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3865—Dental/periodontal tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0093—Features of implants not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material

Abstract

The present invention relates to a treatment method and a tooth treatment method using magnetic teeth. The treatment method according to the present invention comprises the steps of collecting a tooth of a patient in need of an implant procedure; Grinding the tooth into powder; Washing the ground tooth; Dewatering, degreasing and demineralizing the washed tooth; Freeze-drying the dehydrated, degreased and demineralized tooth; Applying the lyophilized tooth to the alveolar bone to be implanted with the patient; It characterized in that it comprises the step of implanting the alveolar bone. This can improve the stability of the implant procedure, it is possible to prevent infectious diseases that can be transferred from allograft material and xenotransplantation material.

Description

Treatment method and magnetic treatment method using magnetic teeth {CURING METHOD USING AUTOTOOTH AND TREATING METHOD OF AUTOTOOTH}

The present invention relates to a method of treatment through magnetic guided bone regeneration (GBR) and a method of treating magnetic teeth during implantation (artificial tooth implantation).

Recently, implant procedures to replace lost teeth are becoming common.

The implant procedure is performed by planting a fixture in the alveolar bone located in the lost tooth, coupling the abutment to the fixture, and then coupling the artificial tooth to the abutment.

How tightly the fixture is secured to the alveolar bone is an important factor in determining the success and lifetime of the implant.

In patients with a prior or acquired lack or alveolar bone, it is difficult to fix the fixture firmly. In this case, the bone graft material consisting of another person's bone or artificial structure is implanted into the alveolar bone and then implanted.

However, in the case of bone graft material made of the bones of others, the problem of immunity occurs, there is a problem that must go through a complex process to remove the problem of immunity. In addition, in the case of bone graft material made of artificial structures, it does not contain bone morphogenetic protein (BMP, bone formation promoting protein), there is a problem that the bone formation rate is low.

It is therefore an object of the present invention to improve the stability of implant procedures and to provide patients with implants that are safe from infectious diseases that spread from others or xenografts (animals).

An object of the present invention comprises the steps of collecting the teeth of the patient is required implant treatment; Grinding the tooth into powder; Washing the ground tooth; Dewatering, degreasing and demineralizing the washed tooth; Freeze-drying the dehydrated, degreased and demineralized tooth; Applying the lyophilized tooth to the alveolar bone to be implanted with the patient; It is achieved by a method of treatment comprising the step of implanting the alveolar bone.

The freeze-dried tooth may further comprise sterilization before applying to the alveolar bone.

The sterilization can be carried out using radiation or ethylene oxide gas.

The washing may include pure washing using ultrasonic waves and hydrogen peroxide washing using ultrasonic waves.

The dehydration may use ethyl alcohol, the degreasing may use ethyl ether, and the deliming may use hydrochloric acid.

After the teeth are dehydrated, degreased and demineralized, further washing the dehydrated, degreased and demineralized teeth; The further washed tooth may further comprise the step of further dehydration and further degreasing.

The object of the present invention is to collect the teeth of the patient; Grinding the tooth into powder; Washing the ground tooth; Dewatering, degreasing and demineralizing the washed tooth; Freeze-drying the dehydrated, degreased and demineralized tooth; It is achieved by a tooth treatment method further comprising sterilizing the lyophilized teeth.

The sterilization can be carried out using radiation or ethylene oxide gas.

The washing may include pure washing using ultrasonic waves and hydrogen peroxide washing using ultrasonic waves.

The dehydration may use ethyl alcohol, the degreasing may use ethyl ether, and the deliming may use hydrochloric acid.

After the teeth are dehydrated, degreased and demineralized, further washing the dehydrated, degreased and demineralized teeth; The further washed tooth may further comprise the step of further dehydration and further degreasing.

According to the present invention it is possible to improve the stability of the implant procedure, and by using their teeth can prevent the infectious diseases that are transmitted from other people or heterogeneous (animal).

Hereinafter, the method of implantation (treatment method) and autologous bone treatment method according to the present invention will be described in detail with reference to the preparation method.

First, autogenous bone is collected from the patient (patient) to be implanted. Autogenous bone can be obtained from the patient's teeth, and in some cases, from the jaw or alveolar bone of another part.

The collected autologous bone is manufactured in powder form through a process of trimming and crushing soft tissue. The size of the powder is 200 μm to 1000 μm, and a size of 1000 μm or more is possible. By grinding, the blood and soft tissue contained in the autogenous bone can be easily and effectively removed.

Next, the crushed autologous bone is washed to remove adhered contaminants and remaining soft tissue. The washing may be performed using an ultrasonic cleaner after placing the crushed autologous bone in demineralized water and / or hydrogen peroxide.

Specifically, three times of about 5-10 minutes each using pure-ultrasound, three times of about 10-30 minutes by using peroxide-ultrasound, and three times of about 5-10 minutes using pure-ultrasound again. The concentration of hydrogen peroxide used for washing may be 5% to 7%. Sterile distilled water can also be used instead of pure water. During the washing process, fat may be suspended in the upper layer, and the suspended fat is washed off with ether. The volume of the wash solution may be used 5 to 10 times the volume of autologous bone. The temperature at the time of ultrasonication may be about 60 ~ 80 ℃.

The washed autologous bone is then dehydrated, degreased and demineralized to reduce graft antigenicity. This process may be performed in the order of, but not limited to, dehydration-degreasing-deliming.

Demineralization and degreasing process removes minerals and fats from the raw materials, leaving only the organic matter in which the protein is present.

Dehydration is done by putting the autologous bone washed in ethanol (ethyl alcohol) for about 10 minutes to 1 hour. At this time, ethanol may be about 5 to 10 times the volume of autologous bone.

Degreasing is performed by putting dehydrated autogenous bone powder in ethyl ether and stirring for 10 minutes to 1 hour.

Demineralization is carried out by putting the degreased autogenous bone powder in a hydrochloric acid solution for 3 to 10 minutes. By deliming, the amount of calcium remaining can be 8% or less. The concentration of hydrochloric acid solution is 0.3N to 0.6N, hydrochloric acid solution can be used about 5ml per 1g of degreased autologous bone. Teeth are harder than other bone tissues, and demineralization removes minerals (mainly calcium) from the teeth, releasing tightly tangled bone fibers to promote bone formation.

Dehydrated, degreased and demineralized autogenous bone powder may be subjected to an additional washing process and may be performed three times for 5-10 minutes using pure-ultrasound.

After further washing, autologous bone powder may be subjected to further dehydration and further degreasing. Further dehydration can also be achieved by stirring for 10 minutes to 1 hour with ethane, and further degreasing can also be achieved by stirring for 10 minutes to 1 hour with ethyl ether.

Further washing, further dehydration and further degreasing process may be omitted during the above procedure.

The autogenous bone powder is then subjected to a freeze-drying process. After freeze-drying, the moisture content is reduced while keeping the tissue intact.

Finally, sterilize the freeze-dried autogenous bone powder. Sterilization can be performed using radiation or ethylene oxide gas.

Finally, the sterilized product is packaged and sent to the hospital where the implant is performed.

In addition, during the above process, foreign matter inspection may be included one or more times, and foreign matter inspection is preferably included immediately before packaging.

In hospitals, lyophilized autologous bone is applied to the alveolar bone where the patient's implant is to be treated. Freeze-dried autologous bone improves the alveolar bone formation rate by the action of the bone-forming protein contained. After the implant on the alveolar bone.

According to the above method, since autologous bone is used in the implant procedure, no immune problem occurs, and the method of treating autologous bone is relatively simple. Therefore, the stability of the implant procedure can be improved.

On the other hand, the autologous bone treated according to the present invention is not only when the alveolar bone that is the implant target is bad, but also in the case of alveolar bone defect, when the horizontal and vertical increase of the alveolar agent is necessary, such as ten (Dehiscences) or perforation (Fenestration). It can be used as a safe self-transplanting material during bone conduction regenerative surgery (GBR).

Claims (11)

Extracting teeth of a patient in need of an implant procedure; Grinding the tooth into powder; Washing the ground tooth; Dewatering, degreasing and demineralizing the washed tooth; Freeze-drying the dehydrated, degreased and demineralized tooth; Applying the lyophilized tooth to the alveolar bone to be implanted with the patient; Treatment method comprising the step of implanting the alveolar bone. The method of claim 1, The method further comprises sterilizing the lyophilized teeth before applying to the alveolar bone. The method of claim 2, The sterilization is carried out using radiation or ethylene oxide gas. The method of claim 1, The washing is, Pure water washing using ultrasonic waves and hydrogen peroxide cleaning using ultrasonic waves. The method of claim 1, The dehydration is using ethyl alcohol, the degreasing is using ethyl ether, the deliming is characterized in that using hydrochloric acid. The method of claim 1, After dehydrating, degreasing and demineralizing the teeth, Further cleaning the dehydrated, degreased and demineralized tooth; And further dehydrating and further degreasing the further washed tooth. Extracting autogenous bone from the patient's teeth; Grinding the tooth into powder; Washing the ground tooth; Dewatering, degreasing and demineralizing the washed tooth; Freeze-drying the dehydrated, degreased and demineralized tooth; Tooth treatment method comprising the step of sterilizing the lyophilized teeth. The method of claim 7, wherein Wherein the sterilization is performed using radiation or ethylene oxide gas. The method of claim 7, wherein The washing is, A tooth treatment method comprising pure water washing using ultrasonic waves and hydrogen peroxide washing using ultrasonic waves. The method of claim 7, wherein The dehydration is using ethyl alcohol, the degreasing is using ethyl ether, the deliming is a tooth treatment method characterized in that using hydrochloric acid. The method of claim 7, wherein After dehydrating, degreasing and demineralizing the teeth, Further cleaning the dehydrated, degreased and demineralized tooth; Tooth treatment method further comprises the step of further dehydration and further degreasing the washed tooth.
KR1020080099523A 2008-10-10 2008-10-10 Curing method using autotooth and treating method of autotooth KR20100040427A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020080099523A KR20100040427A (en) 2008-10-10 2008-10-10 Curing method using autotooth and treating method of autotooth
PCT/KR2009/004490 WO2010041814A2 (en) 2008-10-10 2009-08-12 Dental treatment using patient’s tooth and tooth processing method

Applications Claiming Priority (1)

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KR1020080099523A KR20100040427A (en) 2008-10-10 2008-10-10 Curing method using autotooth and treating method of autotooth

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012057454A2 (en) 2010-10-27 2012-05-03 Park Chang Soo Method for producing a bone transplant material, and bone transplant material produced by same
WO2012018241A3 (en) * 2010-08-05 2012-05-18 Um In Woong Method for processing bone graft material using teeth, and bone graft material processed thereby
WO2012121448A1 (en) * 2011-03-04 2012-09-13 조선대학교산학협력단 Bone graft substitute production method
WO2012173376A2 (en) * 2011-06-12 2012-12-20 Kim Young Guyn Dental restorative material and manufacturing method therefor
WO2012173377A2 (en) * 2011-06-12 2012-12-20 Kim Young Guyn Root canal filling and method for manufacturing same
WO2013108963A1 (en) * 2012-01-17 2013-07-25 Cho Seong-Yong Dental block bone graft and method for manufacturing same
KR101488716B1 (en) * 2012-09-03 2015-02-04 엄인웅 Kit for Regenerating Alveolar Bone
WO2019098459A1 (en) * 2017-11-14 2019-05-23 한국치아은행 주식회사 Method for manufacturing complex for bone grafting and complex for bone grafting manufactured thereby
KR102149847B1 (en) 2019-10-02 2020-08-31 (주)메드파크 Preparing method for dental restorative material, disinfection method for dental powder, and disinfectant for dental powder
KR20210017473A (en) 2019-08-08 2021-02-17 (주)코리아덴탈솔루션 Manufacturing apparatus for bone graft material using autogenous tooth of structure improvement type
KR102326560B1 (en) * 2020-06-29 2021-11-16 김효민 Powder manufacturing method for teeth bone graft and powder for teeth bone graft manufacturied by the method
KR20220001529A (en) * 2020-06-29 2022-01-06 김효민 Manufacturing method for teeth bone graft and teeth bone graft manufacturied by the method

Families Citing this family (2)

* Cited by examiner, † Cited by third party
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CN111658822A (en) * 2020-04-20 2020-09-15 上海交通大学医学院附属第九人民医院 Decalcification method for teeth and acellular decalcification tooth material
CN114795556B (en) * 2022-05-10 2023-05-12 图斯邦柯生物科技(苏州)有限公司 In-vitro dental bone storage and preparation method

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012018241A3 (en) * 2010-08-05 2012-05-18 Um In Woong Method for processing bone graft material using teeth, and bone graft material processed thereby
CN103068415A (en) * 2010-08-05 2013-04-24 严仁雄 Method for processing bone graft material using teeth, and bone graft material processed thereby
WO2012057454A2 (en) 2010-10-27 2012-05-03 Park Chang Soo Method for producing a bone transplant material, and bone transplant material produced by same
WO2012121448A1 (en) * 2011-03-04 2012-09-13 조선대학교산학협력단 Bone graft substitute production method
WO2012173377A3 (en) * 2011-06-12 2013-04-04 Kim Young Guyn Root canal filling and method for manufacturing same
WO2012173376A3 (en) * 2011-06-12 2013-04-04 Kim Young Guyn Dental restorative material and manufacturing method therefor
WO2012173377A2 (en) * 2011-06-12 2012-12-20 Kim Young Guyn Root canal filling and method for manufacturing same
WO2012173376A2 (en) * 2011-06-12 2012-12-20 Kim Young Guyn Dental restorative material and manufacturing method therefor
WO2013108963A1 (en) * 2012-01-17 2013-07-25 Cho Seong-Yong Dental block bone graft and method for manufacturing same
KR101488716B1 (en) * 2012-09-03 2015-02-04 엄인웅 Kit for Regenerating Alveolar Bone
WO2019098459A1 (en) * 2017-11-14 2019-05-23 한국치아은행 주식회사 Method for manufacturing complex for bone grafting and complex for bone grafting manufactured thereby
KR20210017473A (en) 2019-08-08 2021-02-17 (주)코리아덴탈솔루션 Manufacturing apparatus for bone graft material using autogenous tooth of structure improvement type
KR102149847B1 (en) 2019-10-02 2020-08-31 (주)메드파크 Preparing method for dental restorative material, disinfection method for dental powder, and disinfectant for dental powder
KR102326560B1 (en) * 2020-06-29 2021-11-16 김효민 Powder manufacturing method for teeth bone graft and powder for teeth bone graft manufacturied by the method
KR20220001529A (en) * 2020-06-29 2022-01-06 김효민 Manufacturing method for teeth bone graft and teeth bone graft manufacturied by the method

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