KR20090065813A - Method for the preparation of functional cosmetics from bokbunja wine processing waste - Google Patents

Abstract

A method for manufacturing a functional cosmetic product using Rubi Fructus(Bokbunja) wine remnant extract is provided to ensure the excellent effects of antioxidation and whitening. A method for manufacturing a functional cosmetic product using a Rubi Fructus (Bokbunja) remnants comprises: a step of washing, drying and pulverizing a seed of Rubi Fructus, treating remnant with n-hexane and removing oil; a step of adding ethanol to remove ethanol extract; a step of mixing remnant with purified water and heating to obtain hot water extract; and a step of mixing the Rubi Fructus remnant extract with a skin cream or skin essence. A method for producing skin cream is to dissolve the Rubi Fructus wine containing extra virgin olive oil, squalene, tocopherol, coenzyme Q 10 and anthocyanine in a 1,3-butylene glycol and mix with skin cream.

Description

Method for the Preparation of Functional Cosmetics from Bokbunja Wine Processing Waste}

The present invention relates to a method for producing a functional cosmetic using the extract extracted with hot water from the residue (seed) that is discarded in the production of bokbunja wine. In the present invention, after washing the waste seeds discharged from the seed separator after the production of bokbunjaju and dried them for 22 to 26 hours at 50 ~ 70 ℃, using a roll mill (shredding) repeated three to six times to break the seedlings completely After freezing. To prepare the hot water extract, the residue was sequentially extracted with n- hexane and ethanol to remove lipids and ethanol solubles from the seeds. The residue is then mixed with purified water and treated under boiling conditions for 60 minutes to extract soluble hot water. The extracted residue is filtered with a 17G3 glass filter and the extract in the residue is washed with hot water. Extracts were concentrated and concentrated at 50-55 ° C under reduced pressure and lyophilized hydrolyzed tannin extracts of Bokbunja residue hydrothermal extract. It is dissolved in lene glycol and mixed with a cosmetic base to prepare an essence and cream.

Bokbunja is a deciduous shrub of the family Rosaceae and is made from raw fruits of the Rubus coreanus Miquel. Bokbunja grows wild at the foot of the mountain at 50 to 100 meters above sea level in the southern and central regions of Korea. The white flowers bloom in May and the fruits mature in July to August, and the fruits ripen red and then ripen into reddish red. Bokbunja has been used as a herbal medicine mainly by harvesting wild immature fruit and state. Recently, with the development of cultivation technology, the production volume has been steadily increasing around Sununsa, Gochang-gun, Jeollabuk-do, Korea. In 2006, the price was 15,000 tons and the price was 6,000 won per kg. The price is decent compared to the crop.

According to the literature on Bokbunja, it is used for food and medicinal purposes. It is used for soft drinks, jams, teas, alcoholic beverages, etc., and it is known that it is effective in tonic, blood, respiratory diseases, asthma, etc. in folk medicine. For the efficacy of Bokbun from five ancient books, including Dongbobom, the first man heales lack of sensation, lack of semen, and vulgaris. Second, he helps to lighten the body and lighten the hair. Third, to see what is empty, to brighten the eyes, to help the fourth diuretic and to heal the lungs. The fifth woman treats infertility due to the uterine wall, and the sixth antipyretic medicine is used for colds, febrile diseases and cough.

According to modern science, bokbunja pulp is known not only to contain a large amount of red anthocyanin, which is well known as a natural antioxidant, but also to contain various functional ingredients. Bokbunja is processed and distributed in the form of frozen fruit, bokjunja juice, bokbunja jam, and is recognized as a health food and is used in the manufacture of liquid juice or liquor, but processed products using bokbunja are not generalized. This is because bokbunja has a disadvantage in that red color changes to dark brown due to browning due to heat, and thus it is difficult to commercialize. In addition, the bokbunja juice currently in circulation is manufactured using frozen bokbunja or raw fruit, and in the case of fruit juice is finely crushed raw fruit and seeds and pulp together in a filter bag (non-woven fabric) to produce a juice. Bokbunja juice processed in this way has a dark red color and is mainly used for the production of bokbunja beverages and liquor, which is a liquid product.

In the related art related to the present invention, Korean Patent Application No. 10-2000-0073267 (cosmetic composition for whitening treatment comprising bokbunja extract) relates to a whitening cosmetic composition useful for the treatment of symptoms such as blemishes and freckles to obtain excellent whitening effect The present invention relates to a composition of a composite herbal extract containing Bokbunja extract as a main ingredient and optionally containing one or more herbal extracts selected from the group consisting of venom, Astragalus, safflower, gyeji, Yu-Gi-Eui, Ui-in and Aloe vera. In addition, Korean Patent Application No. 10-2000-0073266 (cosmetic composition for protecting the skin comprising a compound herbal extract) is an invention for skin protection cosmetic composition that prevents skin aging and wrinkles, and excellent whitening effect, pulmonary dong, health, roots, cinnamon, Dongguk, Sangsang, Sangbaekpi, Sesame leaf, Astronomical dong, Gyeji, Schisandra chinensis, Ogapi, Bokbunja, Sukjiwang, Gamguk, Cheonggung, Paekhasuo, Dougong, Tongkeok, Dokyeong, Baekchul, Taeksa, Baekbokyeong, Uiin, Honghwaja, Pogongyeong, Sanjoin, Wooseol, Sansuyu The present invention relates to a composition of the extract obtained from extracts, tea leaves, lobules, Astragalus, hwalyeob, lobar, motherwort, aloe vera and yin yang herb. However, these are different technical configurations from the present invention.

The present invention is to find the active ingredient suitable for cosmetics from the hot water extracts of pulmonary bokbunja seed seed, and the bokbunja liquor containing natural antioxidants and anthocyanin pigments and alcohols and various organic acids as a raw material for the cosmetics, completely washed washed bokbunja seeds in order to obtain the useful components from the crushed residue n - sequentially extracted with hexane (n -hexane) and ethanol, to remove unwanted components such as lipid and ethanol extracts. Again, purified water is mixed with bokbunja residue, extracted from hot water, the extracted residue is filtered, hot water extract is obtained, and it is concentrated under reduced pressure and freeze-dried.

The present invention freezes the crushed residue by completely drying the washed bokbunja seeds. The bokbunja residue was treated with n- hexane to remove the oil component, and ethanol was added to the residue from which the oil component was removed to remove the ethanol extract. Purified water is mixed with the oil-free residue and ethanol extract is removed, heat is applied, and the hot water extract is concentrated under reduced pressure, and freeze-dried. Was dissolved in 1,3-butylene glycol and mixed with the cosmetic substrate to prepare an essence and cream.

The present invention finds a strong antioxidant activity and whitening effect activity from the hot water extracts of the bokbunja seeds, and prepared a skin cream and skin essence using these active substances as a cosmetic composition to provide a neutral and weak dry skin cosmetics, from the elderly Moisturizes the skin for a long time, feels good, has a natural and proper color and aroma, absorbs and spreads, and has the same or better performance than most cosmetics Was evaluated. In addition, the present invention is expected to be able to expand the use of bokbunja wine by using an anthocyanin pigments, alcohols and natural organic acids, as a raw material for bokbunja wine is used as a cosmetic raw material

The manufacturing method of cosmetics using a bokbunja residue extract is shown.

The present invention comprises the steps of removing the oil component by treating the residue obtained by crushing the dried bokbunja seeds completely washed with n- hexane,

Removing ethanol extract by adding ethanol to the oil-free residue;

Mixing purified water to the residue from which the ethanol extract has been removed and applying heat to obtain a hot water extract and concentrating it to freeze-drying;

Represents a method for producing cosmetics using the bokbunja residue extract comprising the step of mixing the skin cream or skin essence base to the bokbunja residue hot water extract.

The skin cream may be dissolved in 1,3-butylene glycol bokbunjaju containing extra virgin olive oil, squalene, tocopherol, coenzyme Q10 and anthocyanin in bokbunja residue hot water extract can be mixed with a known substrate.

The skin cream is an oily silicone complex, an aqueous olive oil, squalene, tocopherol, coenzyme Q10, a flavoring agent, a preservative, and additives as purified water, D-EDTA, sodium hyaluronate, medicinal plant extracts, glycerin, 1,3- Butylene glycol, bokbunja residue extract, bokbunja wine can be mixed.

The skin essence may be mixed with a known substrate by dissolving bokbunjaju containing extra virgin olive oil, coenzyme Q10 and anthocyanin in 1,3-butylene glycol in bokbunja residue hydrothermal extract.

Skin essence is a mixture of purified water, 1,3-butylene glycol, glycerin, xanthan gum, carboxyvinyl polymer, ethanol, polyethylene glycol (PEG), flavoring, preservatives, olive oil and dispersed, neutralized by adding purified water and TEA Bokbunja seed hot water extract, bokbunjaju, sodium hyaluronate, medicinal plant extract, coenzyme Q10, tocopherol acetate, PEG and erythritol, purified water can be added.

The present invention may further use a functional material to improve the functionality of the cosmetic when manufacturing bokbunja cosmetics using bokbunja seeds.

The present invention may further add a functional material in the step of mixing the skin cream or skin essence base in the bokbunja residue hot water extract to improve the functionality of the cosmetic when manufacturing bokbunja cosmetics using bokbunja seeds.

The functional material for improving the functionality of the bokbunja cosmetics may be used 0.1 to 5 parts by weight based on 100 parts by weight of bokbunja residue hot water extract.

The functional substances in the ginseng, red ginseng, ginseng, camphor ginseng, Angelica, bokyeong, danja, Schisandra chinensis, Sangbaekpi, Baekchul, Gilkyung, Macmun-dong, motherwort, hamcho, Cheonma, tofu, aloe, ogapi, cornus, turmeric, trichophyte herb, object , Machi, quince, forget-me-not, macmundong, chicory, gardenia, poncho root, ginkgo, ginkgo biloba, safflower seed, mulberry leaf, chlorella, chestnut, pumpkin, green tea, carrot, cucumber, yujapi, quince peel have.

The functional material may be used in a solid form of a powder, and as an example of such a powder, a functional material powder pulverized to a particle size of 1 to 1000 μm may be used by putting the functional material into a grinder.

The functional material may be used in the liquid form of the hot water extract. As an example of such hot water extract, the functional material is placed in purified water at 3 to 10 times the weight of the functional material and 10 to the volume of the first purified water at a temperature of 80 to 100 ° C. The functional material hot water extract extracted until it reaches 50% can be used.

The functional material may be compatible with any one or more forms selected from solid form of powder and liquid form of hot water extract.

Since the formulation of the powder, extract form in the functional material can be appropriately selected by those skilled in the art will be omitted for the details thereof.

Hereinafter, the present invention will be described in detail with reference to each step.

<Acquisition and pretreatment of bokbunja seed residue>

After the preparation of bokbunjaju, residue seeds and fresh bokbunja seeds were obtained from Gochang dolmen bokbunja. Traces of pulp and pigments present on the surface of the seeds were washed several times and completely removed, and dried at 60 ℃ for 24 hours. The dried seeds were crushed using a roll mill until the seedlings were completely broken (six times of crushing). The crushed powder was stored frozen to prevent deterioration and used as a test material for extracting oil and active substances. The moisture contained in the seed powder was calculated from the reduced weight after drying at 105 ° C. for 24 hours. Extraction components obtained from residue seeds after the preparation of bokbunja wine were expressed as wine Bokbunja seed (WBS), and extracts prepared from fresh bokbunja seeds were expressed as fresh Bokbunja seed (FBS).

<Physiological Activity and Skin Activity of Bokbunja Hot Water Extract>

(1) antioxidant activity

Hot water extracts are likely to be composed of phenolic acids or flavonoid glycosides including low molecular weight ellagitannin. Hot water extracts from fresh bokbunja seeds (FBS) and wine bokbunja seeds (WBS) were used to evaluate the scavenging activity of ABTS cationic radicals of antioxidants. FBS and WBS were 95% at concentrations of 40 and 70 µg / ml or more, respectively. It showed high activity and showed similar results with comparative antioxidants. From these results, FBS and WBS could be used as a useful raw material for the purpose of healing skin diseases or diseases associated with lipid oxidation. In vivo studies on this part are not only applied as functional cosmetics, but also foods. It would be helpful to prepare a way to use bokbunja as a high value-added industry such as pharmaceuticals and pharmaceuticals.

(2) Linoleic acid oxidation inhibition

Figure 2 shows what linoleic acid exhibits a peroxidation pattern over time in 105 ℃, DMSO solvent conditions. In the case of control, it can be seen that it undergoes rapid oxidation from the beginning, and it can be seen that the addition of antioxidant requires a lag time that leads to oxidation. From this, the linoleic acid oxidation inhibitory effect of antioxidants could be evaluated according to the delay of the lag time, which can be seen as the time when epoxide bond is formed in double bond of unsaturated fatty acid. FBS and WBS, the main component of ellagitannin, significantly inhibits the oxidation of linoleic acid as shown in FIG. From these results, FBS and WBS could be used as a useful material for the purpose of healing skin diseases or diseases associated with lipid oxidation.

(3) Tyrosinase Inhibitory Activity

FIG. 3 shows the result of measuring the absorbance at 475 nm attributable to L-DOPA oxide to inhibit enzymatic activity as the concentration of tyrosinase inhibitor was increased. FBS and WBS showed inhibition rates of 8.9 and 12.5% at 286 ㎍ / ㎖, respectively, but lower inhibition rates than proantocyanidin or tannic acid. These results suggest that FBS and WBS inhibit the tyrosinase by a mechanism similar to commercial glycoside whitening agents (ascorbic acid-2-glucoside and arbutin) because they have the form of HHDP or valoneic acid bilactone binding to the glucoside moiety. In other words, in this experiment, it was determined that glucose showed some limited results because it was difficult to act as an oxidative substrate of tyrosinase in the free state. From the above results, it can be seen that the hydrothermal extract can inhibit tyrosinase.

(4) melanin production inhibitory effect

Table 1 shows the melanogenesis inhibitory effect of FBS and WBS on normal melanocytes. As can be seen, FBS and WBS showed 25.8 and 14.3% melanogenesis inhibitory effects on melanocytes, respectively, and FBS was twice as high as WBS.

Table 1. Inhibitory Effects of Hot Water Extracts of Bokbunja Seeds on Melanin Production

sample Concentration (%) Melanin production inhibitory effect (%) Fresh Bokbunja Seed 0.01 25.8 Wine Bokbunja Seed 0.01 14.3

In the manufacture of cosmetics using the bokbunja residue extract of the present invention, the cosmetics using the bokbunja residue extract under the conditions of various components, content, etc., to achieve the object of the present invention Bokbunja under the conditions described below It is desirable to provide cosmetics using the residue extract.

Hereinafter, the content of the present invention will be described in detail through examples and test examples. However, these are intended to explain the present invention in more detail, and the scope of the present invention is not limited thereto.

<Example>; Preparation of Bokbunja Cream and Essence Using Hot Water Extract

Cream and essence using waste seed hot water extract after the manufacture of bokbunja were developed with the focus on the middle-aged women and neutral skin. Bokbunja effective extract has an excellent antioxidant effect and whitening effect, and the hydrothermal extract mainly composed of hydrolyzed tannin is dissolved in 50% 1,3-butylene glycol to prepare a 1% solution, which is shown in the following Tables 2 and 3 Various functional additives were prepared as if. Prototyping and basic testing were commissioned by Philos Co., Ltd. A brief cream preparation method (Table 2) is prepared by stirring phase A (oil phase) and phase B (water phase) respectively, then adding phase B to phase A (room temperature) and slowly adding phase C (additives) to the mixture. It was. The preparation of the essence was neutralized by adding A to B, uniformly dispersing C, and adding D and E thereto to produce the essence.

Coenzyme Q10, a natural tocopherol of extra virgin olive oil, squalane, etc., which can have synergistic effect with bokbunja seed functional ingredients, was added to prepare the prototype for anti-aging. In addition, a natural antioxidant, anthocyanin, is added using a large amount of bokbunjaju, and hydrolyzed tannin-containing hot water extract is dissolved in 50% 1,3-butylene glycol to prepare a 1% solution, followed by the following Tables 2 and 3 Various functional additives were added as shown in FIG. Prototyping and basic testing were commissioned by Philos Co., Ltd. A brief cream preparation method (Table 2) is prepared by stirring phase A (oil phase) and phase B (water phase) respectively, then adding phase B to phase A (room temperature) and slowly adding phase C (additives) to the mixture. It was. The preparation of the essence was neutralized by adding A to B and uniformly dispersing C after referring to Table 3, and adding D and E thereto to commercialize it.

<Test Example>; Investigation of prototype response

Essences and creams prepared from Bokbunja seed extract were used as a main ingredient for 20 weeks of randomly selected middle aged women aged 38 to 70 years. The analysis was divided into neutral, dry and oily skin, and each response was separated and statistically processed. (1) The cosmetics are very light and matte, and the skin's moisturizing seems to last for a long time. (2) The feeling is good. (3) 65% of users judged that the performance was almost the same as or higher than the cosmetics used previously. (4) The color and aroma are natural and suitable. (5) The degree of absorption and spreading is excellent.

Bokbunja seed extract has a strong antioxidant and whitening effect, such that as much as possible to prepare a cream and essence. As a result of supplying these cosmetics to participants and conducting a test for a week, it was determined that 65% of the participants were similar or better than the existing cosmetics, and thus the commercialization of the extract-containing cosmetics was confirmed.

Its main ingredient is bokbunja residue seed extract, which has been proven to be effective in whitening and anti-aging, and contains neutral tocopherol, squalene, and coenzyme Q10, which is a bioactive substance of human body, in natural virgin and extra virgin olive oil. Creams and essences were prepared for the middle-aged female layer of slightly dry skin. In addition, Bokbunja wine was added as a substitute for natural flavors, pigments and alcohol.

Creams and essences of Table 2 and Table 3, which are the optimum raw material blending conditions, were prepared through preliminary skin experiments and affinity tests. Since the cosmetics of the present invention are aimed at middle-aged women with mild to dry skin, a study for expanding their use will be needed.

Table 2. Compositions for Skin Cream

 WBS: hydrothermal extract of bokbunja seeds, BBJ-OH; Bokbunja Note

Table 3. Composition for Skin Essence

As described above, although described with reference to a preferred embodiment of the present invention, those skilled in the art will be variously modified and modified within the scope of the present invention without departing from the spirit and scope of the invention described in the claims below. It will be appreciated that it can be changed.

The cosmetics of the present invention are very light and matte, and after use, the skin moisturizes for a long time, so the feeling is good, and most of the users have judged that the performance is almost the same as or more than the existing cosmetics. In addition, the color and fragrance is natural and suitable, and the absorption and spreading are excellent. Therefore, manufacturing cosmetics using ingredients extracted from bokbunja seeds is useful for farms, bokbunja manufacturing companies, and consumers, so the industrial applicability is great.

1 is an active ingredient manufacturing process chart of the present invention.

Figure 2 is a diagram showing the linoleic acid peroxide inhibitory effect of the waste seed hydrothermal extract after the preparation of bokbunja main of the present invention.

Figure 3 is a diagram showing the tyrosinase inhibitory activity of the waste seed hydrothermal extract after the preparation of bokbunja main of the present invention.

Claims (5)

Completely drying the washed bokbunja seeds, crushing the residue, and treating the residue with n- hexane to remove the oil component; Removing ethanol extract by adding ethanol to the oil-free residue; Mixing purified water to the residue from which the ethanol extract has been removed and applying heat to obtain a hot water extract and concentrating it to freeze-drying; Method for producing cosmetics using the bokbunja residue extract comprising the step of mixing the skin cream or skin essence base with bokbunja residue hot water extract The method of claim 1, wherein the skin cream is bokbunja characterized in that the bokbunjaju containing extra virgin olive oil, squalene, tocopherol, coenzyme Q10 and anthocyanin in bokbunja residue hot water extract is mixed with a known substrate in 1,3-butylene glycol Manufacturing method of cosmetics using residue extract The skin cream according to claim 2, wherein the skin cream is an oily silicone compound, an aqueous olive oil, squalene, tocopherol, coenzyme Q10, a flavoring agent, a preservative, and an additive, purified water, D-EDTA, sodium hyaluronate, medicinal plant extract, glycerin, 1,3-butylene glycol, bokbunja residue extract, manufacturing method of cosmetics using bokbunja residue extract, characterized in that The method of claim 1, wherein the skin essence is dissolved in 1,3-butylene glycol bokbunjaju containing extra virgin olive oil, coenzyme Q10 and anthocyanin in the bokbunja residue hot water extract and mixed with a known substrate Manufacturing method of cosmetics According to claim 4, Skin essence is a mixture of purified water, 1,3-butylene glycol, glycerin, xanthan gum, carboxyvinyl polymer ethanol, PEG, fragrance, preservatives, olive oil and dispersed, neutralized by adding purified water and TEA Bokbunja Seed Hydrothermal Extract, Bokbunjaju, Hyaluronic Acid Soda, Medicinal Plant Extract, Coenzyme Q10, Tocopherol Acetate, PEG and Erythritol, Method of producing cosmetics using bokbunja residue extract, characterized in that the addition of purified water

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