KR20090013736A - 메트포르민 산 부가염을 포함하는 서방성 제제 - Google Patents

메트포르민 산 부가염을 포함하는 서방성 제제 Download PDF

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Publication number
KR20090013736A
KR20090013736A KR1020080075765A KR20080075765A KR20090013736A KR 20090013736 A KR20090013736 A KR 20090013736A KR 1020080075765 A KR1020080075765 A KR 1020080075765A KR 20080075765 A KR20080075765 A KR 20080075765A KR 20090013736 A KR20090013736 A KR 20090013736A
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KR
South Korea
Prior art keywords
metformin
sustained
acid addition
release
addition salt
Prior art date
Application number
KR1020080075765A
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English (en)
Korean (ko)
Inventor
원권연
김동욱
신동성
김경운
Original Assignee
주식회사 한독약품
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Publication date
Application filed by 주식회사 한독약품 filed Critical 주식회사 한독약품
Publication of KR20090013736A publication Critical patent/KR20090013736A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020080075765A 2007-08-02 2008-08-01 메트포르민 산 부가염을 포함하는 서방성 제제 KR20090013736A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020070077696 2007-08-02
KR20070077696 2007-08-02

Publications (1)

Publication Number Publication Date
KR20090013736A true KR20090013736A (ko) 2009-02-05

Family

ID=40305070

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020080075765A KR20090013736A (ko) 2007-08-02 2008-08-01 메트포르민 산 부가염을 포함하는 서방성 제제

Country Status (3)

Country Link
KR (1) KR20090013736A (fr)
TW (1) TW200906383A (fr)
WO (1) WO2009017383A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011008054A2 (fr) * 2009-07-17 2011-01-20 한올바이오파마주식회사 Sel d'acide butyrique de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation, ainsi que compositions et combinaisons pharmaceutiques le contenant
WO2011008053A2 (fr) * 2009-07-17 2011-01-20 한올바이오파마주식회사 Propionate de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation ainsi que compositions et combinaisons pharmaceutiques le contenant

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3056908B1 (fr) * 2016-09-30 2019-04-19 Nashpharm Sel de metformine et d'elafibranor presentant une activite duale pour le traitement de l'obesite associee a la steato-hepatite non alcoolique (nash) et a l'hypertriglyceridemie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA007610B1 (ru) * 1998-11-12 2006-12-29 Смитклайн Бичам Плс Таблетка с энтеропокрытием, обеспечивающая отсроченное высвобождение
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
EP1510208A1 (fr) * 2003-08-22 2005-03-02 Fournier Laboratories Ireland Limited Compositions pharmaceutiques comprenant une combinaison de metformine et de statine
EP1591114A1 (fr) * 2004-03-12 2005-11-02 Fournier Laboratories Ireland Limited Utilisation de la metformine et de l'Orlistat pour le traitement ou la prévention de l'obésité

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011008054A2 (fr) * 2009-07-17 2011-01-20 한올바이오파마주식회사 Sel d'acide butyrique de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation, ainsi que compositions et combinaisons pharmaceutiques le contenant
WO2011008053A2 (fr) * 2009-07-17 2011-01-20 한올바이오파마주식회사 Propionate de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation ainsi que compositions et combinaisons pharmaceutiques le contenant
WO2011008053A3 (fr) * 2009-07-17 2011-04-21 한올바이오파마주식회사 Propionate de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation ainsi que compositions et combinaisons pharmaceutiques le contenant
WO2011008054A3 (fr) * 2009-07-17 2011-04-21 한올바이오파마주식회사 Sel d'acide butyrique de n,n-diméthyl diamide imidocarbonimidique, son procédé de préparation, ainsi que compositions et combinaisons pharmaceutiques le contenant

Also Published As

Publication number Publication date
WO2009017383A3 (fr) 2009-04-09
WO2009017383A2 (fr) 2009-02-05
TW200906383A (en) 2009-02-16

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