KR20080079301A - Ｃｄ４０ 결합제를 이용하는 방법 - Google Patents
Ｃｄ４０ 결합제를 이용하는 방법 Download PDFInfo
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- KR20080079301A KR20080079301A KR1020087016629A KR20087016629A KR20080079301A KR 20080079301 A KR20080079301 A KR 20080079301A KR 1020087016629 A KR1020087016629 A KR 1020087016629A KR 20087016629 A KR20087016629 A KR 20087016629A KR 20080079301 A KR20080079301 A KR 20080079301A
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- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10072087B2 (en) | 2009-12-10 | 2018-09-11 | Hoffmann-La Roche Inc. | Antibodies against human CSF-1R and uses thereof |
| US11498968B2 (en) | 2016-12-22 | 2022-11-15 | Hoffmann-La Roche Inc. | Treatment of tumors with an anti-CSF-1R antibody in combination with an anti-PD-L1 antibody after failure of anti-PD-L1/PD1 treatment |
| US11512133B2 (en) | 2013-09-12 | 2022-11-29 | Hoffmann-La Roche Inc. | Methods for treating colon cancer or inhibiting cell proliferation by administering a combination of antibodies against human CSF-1R and antibodies against human PD-L1 |
| US11542335B2 (en) | 2016-08-25 | 2023-01-03 | Hoffmann-La Roche Inc. | Method of treating cancer in a patient by administering an antibody which binds colony stimulating factor-1 receptor (CSF-1R) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| KR20100088621A (ko) * | 2007-11-09 | 2010-08-09 | 노파르티스 아게 | 항-ｃｄ40 항체의 용도 |
| AU2009206506B2 (en) * | 2008-01-23 | 2013-01-10 | Xencor, Inc. | Optimized CD40 antibodies and methods of using the same |
| BRPI1011394A8 (pt) | 2009-04-18 | 2018-06-26 | Genentech Inc | método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40 |
| CA2789071C (en) | 2010-03-05 | 2018-03-27 | F. Hoffmann-La Roche Ag | Antibodies against human csf-1r and uses thereof |
| BR112012020372A8 (pt) | 2010-03-05 | 2018-01-02 | Hoffmann La Roche | anticorpo que se liga ao csf-1r humano, composição farmacêutica, ácido nucleico, vetores de expressão, célula hospedeira e método para a produção de um anticorpo recombinante |
| PL2683406T3 (pl) | 2011-03-11 | 2019-11-29 | Beth Israel Deaconess Medical Ct Inc | Przeciwciała anty-cd40 i ich zastosowania |
| AU2012249454B2 (en) | 2011-04-29 | 2016-03-24 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
| US10023643B2 (en) | 2011-12-15 | 2018-07-17 | Hoffmann-La Roche Inc. | Antibodies against human CSF-1R and uses thereof |
| AR090263A1 (es) * | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
| US9676861B2 (en) * | 2012-10-30 | 2017-06-13 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| AR095882A1 (es) | 2013-04-22 | 2015-11-18 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9 |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| CN113912723A (zh) | 2014-03-24 | 2022-01-11 | 癌症研究技术有限公司 | 含有修饰IgG2结构域的引起激动或拮抗特性的修饰抗体及其用途 |
| BR112017004614A2 (pt) | 2014-09-09 | 2018-02-27 | Janssen Biotech, Inc. | terapias de combinação com anticorpos anti-cd38 |
| CN107073118B (zh) * | 2014-10-29 | 2022-03-01 | 西雅图基因公司 | 非岩藻糖基化抗cd40抗体的剂量和给药 |
| EA202092609A1 (ru) | 2014-12-04 | 2021-10-29 | Янссен Байотек, Инк. | Антитела к cd38 для лечения острого миелолейкоза |
| CN108136218B (zh) | 2015-05-20 | 2022-12-13 | 詹森生物科技公司 | 用于治疗轻链淀粉样变性及其它cd38阳性血液恶性肿瘤的抗cd38抗体 |
| NZ777133A (en) | 2015-06-22 | 2025-05-02 | Janssen Biotech Inc | Combination therapies for heme malignancies with anti-cd38 antibodies and survivin inhibitors |
| US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
| SI3307322T1 (sl) * | 2015-09-04 | 2021-08-31 | Primatope Therapeutics Inc. | Humanizirana protitelesa proti CD40 in njihove uporabe |
| RS61651B1 (sr) | 2015-11-03 | 2021-04-29 | Janssen Biotech Inc | Potkožne formulacije anti-cd38 antitela i njihova upotreba |
| US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
| US10918627B2 (en) | 2016-05-11 | 2021-02-16 | Massachusetts Institute Of Technology | Convergent and enantioselective total synthesis of Communesin analogs |
| US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
| JP2021502961A (ja) | 2017-10-31 | 2021-02-04 | ヤンセン バイオテツク，インコーポレーテツド | 高リスク多発性骨髄腫の治療方法 |
| AU2019287765A1 (en) | 2018-06-15 | 2021-01-07 | Flagship Pioneering Innovations V, Inc. | Increasing immune activity through modulation of postcellular signaling factors |
| MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
| EP4076434A1 (en) | 2019-12-17 | 2022-10-26 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| CA3184366A1 (en) | 2020-06-29 | 2022-01-06 | Darby Rye Schmidt | Viruses engineered to promote thanotransmission and their use in treating cancer |
| JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
| WO2022266496A1 (en) * | 2021-06-17 | 2022-12-22 | Parker Institute For Cancer Immunotherapy | Methods of treating kras mutation subtypes with cd40 agonist |
| AU2022303363A1 (en) | 2021-06-29 | 2024-01-18 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| EP4598946A1 (en) | 2022-10-05 | 2025-08-13 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| US20240269251A1 (en) | 2023-01-09 | 2024-08-15 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946129B1 (en) * | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| AU2001266557A1 (en) * | 2000-04-12 | 2001-10-23 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| CA2440831C (en) * | 2001-04-02 | 2013-05-28 | Genentech, Inc. | Combination therapy using cd40 and cd20 ligands |
| US20050136055A1 (en) * | 2003-12-22 | 2005-06-23 | Pfizer Inc | CD40 antibody formulation and methods |
| AU2005247301B2 (en) * | 2004-04-16 | 2011-08-18 | Macrogenics, Inc. | FCγRIIB-specific antibodies and methods of use thereof |
| EP1742660A2 (en) * | 2004-04-16 | 2007-01-17 | Genentech, Inc. | Treatment of disorders |
| ES2354865T3 (es) * | 2005-05-26 | 2011-03-18 | Seattle Genetics, Inc. | Anticuerpos anti-cd40 humanizados y métodos para utilizarlos. |
-
2006
- 2006-12-11 WO PCT/US2006/047308 patent/WO2007075326A2/en not_active Ceased
- 2006-12-11 KR KR1020087016629A patent/KR20080079301A/ko not_active Withdrawn
- 2006-12-11 JP JP2008544586A patent/JP2009518441A/ja active Pending
- 2006-12-11 BR BRPI0619586A patent/BRPI0619586A2/pt not_active Application Discontinuation
- 2006-12-11 MX MX2008007140A patent/MX2008007140A/es not_active Application Discontinuation
- 2006-12-11 US US12/302,743 patent/US20090304687A1/en not_active Abandoned
- 2006-12-11 CA CA002632698A patent/CA2632698A1/en not_active Abandoned
- 2006-12-11 EP EP06849940A patent/EP1968636A4/en not_active Withdrawn
- 2006-12-11 AU AU2006329944A patent/AU2006329944A1/en not_active Abandoned
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2008
- 2008-06-05 IL IL191990A patent/IL191990A0/en unknown
- 2008-07-03 NO NO20083002A patent/NO20083002L/no not_active Application Discontinuation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10072087B2 (en) | 2009-12-10 | 2018-09-11 | Hoffmann-La Roche Inc. | Antibodies against human CSF-1R and uses thereof |
| US11512133B2 (en) | 2013-09-12 | 2022-11-29 | Hoffmann-La Roche Inc. | Methods for treating colon cancer or inhibiting cell proliferation by administering a combination of antibodies against human CSF-1R and antibodies against human PD-L1 |
| US11542335B2 (en) | 2016-08-25 | 2023-01-03 | Hoffmann-La Roche Inc. | Method of treating cancer in a patient by administering an antibody which binds colony stimulating factor-1 receptor (CSF-1R) |
| US11498968B2 (en) | 2016-12-22 | 2022-11-15 | Hoffmann-La Roche Inc. | Treatment of tumors with an anti-CSF-1R antibody in combination with an anti-PD-L1 antibody after failure of anti-PD-L1/PD1 treatment |
Also Published As
| Publication number | Publication date |
|---|---|
| IL191990A0 (en) | 2008-12-29 |
| NO20083002L (no) | 2008-08-14 |
| CA2632698A1 (en) | 2007-07-05 |
| JP2009518441A (ja) | 2009-05-07 |
| EP1968636A4 (en) | 2010-06-02 |
| BRPI0619586A2 (pt) | 2018-08-28 |
| US20090304687A1 (en) | 2009-12-10 |
| EP1968636A2 (en) | 2008-09-17 |
| MX2008007140A (es) | 2009-03-04 |
| WO2007075326A3 (en) | 2008-09-04 |
| AU2006329944A1 (en) | 2007-07-05 |
| WO2007075326A2 (en) | 2007-07-05 |
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| PA0105 | International application |
Patent event date: 20080708 Patent event code: PA01051R01D Comment text: International Patent Application |
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| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |