KR20080040676A - 항미생물제로서의 tfpi 단편 - Google Patents

항미생물제로서의 tfpi 단편 Download PDF

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Publication number
KR20080040676A
KR20080040676A KR1020087001728A KR20087001728A KR20080040676A KR 20080040676 A KR20080040676 A KR 20080040676A KR 1020087001728 A KR1020087001728 A KR 1020087001728A KR 20087001728 A KR20087001728 A KR 20087001728A KR 20080040676 A KR20080040676 A KR 20080040676A
Authority
KR
South Korea
Prior art keywords
tfpi
polypeptide
lys
peptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020087001728A
Other languages
English (en)
Korean (ko)
Inventor
사빈 쉬름
스테펜 하디
Original Assignee
노파르티스 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR20080040676A publication Critical patent/KR20080040676A/ko
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020087001728A 2005-07-22 2006-07-24 항미생물제로서의 tfpi 단편 Withdrawn KR20080040676A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70204905P 2005-07-22 2005-07-22
US60/702,049 2005-07-22
US72251205P 2005-09-29 2005-09-29
US60/722,512 2005-09-29

Publications (1)

Publication Number Publication Date
KR20080040676A true KR20080040676A (ko) 2008-05-08

Family

ID=37683904

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020087001728A Withdrawn KR20080040676A (ko) 2005-07-22 2006-07-24 항미생물제로서의 tfpi 단편

Country Status (9)

Country Link
US (1) US20090176701A1 (https=)
EP (1) EP1913025A2 (https=)
JP (1) JP2009502810A (https=)
KR (1) KR20080040676A (https=)
AU (1) AU2006272653A1 (https=)
BR (1) BRPI0613676A2 (https=)
CA (1) CA2615777A1 (https=)
RU (1) RU2008106460A (https=)
WO (1) WO2007014199A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009129164A1 (en) * 2008-04-15 2009-10-22 Novartis Ag Pharmaceutical combinations of tfpi-fragments and an antibiotic
GB0916578D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
WO2023142096A1 (en) * 2022-01-30 2023-08-03 Westlake University Composition and method for preventing and/or treating clostridioides difficile infections caused by clade 2 strains

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589359A (en) * 1994-08-05 1996-12-31 Chiron Corporation Chimeric proteins
EP1446140A4 (en) * 2001-10-15 2007-03-07 Novartis Vaccines & Diagnostic TREATMENT OF HEAVY PNEUMONIA BY ADMINISTRATION OF TFPI (TISSUE FACTOR PATHWAY INHIBITOR)

Also Published As

Publication number Publication date
WO2007014199A3 (en) 2007-05-24
JP2009502810A (ja) 2009-01-29
BRPI0613676A2 (pt) 2011-01-25
RU2008106460A (ru) 2009-08-27
AU2006272653A1 (en) 2007-02-01
US20090176701A1 (en) 2009-07-09
EP1913025A2 (en) 2008-04-23
WO2007014199A2 (en) 2007-02-01
CA2615777A1 (en) 2007-02-01

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20080122

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid