KR20070100331A - 새로운 아데노신 에이3 수용체 조절제 - Google Patents

새로운 아데노신 에이3 수용체 조절제 Download PDF

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Publication number
KR20070100331A
KR20070100331A KR1020077017126A KR20077017126A KR20070100331A KR 20070100331 A KR20070100331 A KR 20070100331A KR 1020077017126 A KR1020077017126 A KR 1020077017126A KR 20077017126 A KR20077017126 A KR 20077017126A KR 20070100331 A KR20070100331 A KR 20070100331A
Authority
KR
South Korea
Prior art keywords
dione
compound
purine
substituted
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020077017126A
Other languages
English (en)
Korean (ko)
Inventor
피어 바랄디
피어 안드레아 보레아
델리아 프레티
모즈간 아가자데 타브리지
Original Assignee
킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 filed Critical 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨
Publication of KR20070100331A publication Critical patent/KR20070100331A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020077017126A 2005-02-02 2006-02-01 새로운 아데노신 에이3 수용체 조절제 Ceased KR20070100331A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64972605P 2005-02-02 2005-02-02
US60/649,726 2005-02-02
US11/344,295 2006-01-31
US11/344,295 US7435740B2 (en) 2005-02-02 2006-01-31 Adenosine A3 receptor modulators

Publications (1)

Publication Number Publication Date
KR20070100331A true KR20070100331A (ko) 2007-10-10

Family

ID=36777854

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077017126A Ceased KR20070100331A (ko) 2005-02-02 2006-02-01 새로운 아데노신 에이3 수용체 조절제

Country Status (11)

Country Link
US (1) US7435740B2 (enExample)
EP (1) EP1845993A4 (enExample)
JP (1) JP2008538099A (enExample)
KR (1) KR20070100331A (enExample)
AU (1) AU2006210817B2 (enExample)
BR (1) BRPI0606750A2 (enExample)
CA (1) CA2596612A1 (enExample)
IL (1) IL184532A0 (enExample)
MX (1) MX2007008501A (enExample)
NZ (1) NZ556649A (enExample)
WO (1) WO2006083916A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088403A1 (en) * 2007-05-07 2009-04-02 Randy Blakely A3 adenosine receptors as targets for the modulation of central serotonergic signaling
US8765775B2 (en) 2008-01-24 2014-07-01 Universitaet Zuerich Anti-angiogenic compounds
US20110190324A1 (en) * 2008-07-16 2011-08-04 Edward Leung Methods of treating atherosclerosis
US9199102B2 (en) 2009-07-21 2015-12-01 Oradin Pharmaceutical Ltd. A3 adenosine receptor ligands for modulation of pigmentation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses

Also Published As

Publication number Publication date
JP2008538099A (ja) 2008-10-09
BRPI0606750A2 (pt) 2009-07-14
AU2006210817A2 (en) 2006-08-10
US7435740B2 (en) 2008-10-14
CA2596612A1 (en) 2006-08-10
AU2006210817B2 (en) 2010-12-23
EP1845993A2 (en) 2007-10-24
EP1845993A4 (en) 2009-03-11
WO2006083916A2 (en) 2006-08-10
WO2006083916A3 (en) 2007-12-21
US20060178385A1 (en) 2006-08-10
MX2007008501A (es) 2007-09-14
NZ556649A (en) 2010-03-26
AU2006210817A1 (en) 2006-08-10
IL184532A0 (en) 2007-10-31

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PA0105 International application

Patent event date: 20070725

Patent event code: PA01051R01D

Comment text: International Patent Application

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Patent event code: PA02012R01D

Patent event date: 20101007

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Patent event date: 20120621

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20121231

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20120621

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I