BRPI0606750A2 - composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica - Google Patents

composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica

Info

Publication number
BRPI0606750A2
BRPI0606750A2 BRPI0606750-6A BRPI0606750A BRPI0606750A2 BR PI0606750 A2 BRPI0606750 A2 BR PI0606750A2 BR PI0606750 A BRPI0606750 A BR PI0606750A BR PI0606750 A2 BRPI0606750 A2 BR PI0606750A2
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutically acceptable
pharmaceutical composition
acceptable salt
receptor
Prior art date
Application number
BRPI0606750-6A
Other languages
English (en)
Inventor
Pier Andrea Borea
Delia Preti
Mojgan Aghzadeh Tabrizi
Pier Baraldi
Original Assignee
King Pharmaceuticals Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by King Pharmaceuticals Res & Dev filed Critical King Pharmaceuticals Res & Dev
Publication of BRPI0606750A2 publication Critical patent/BRPI0606750A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPOSTO OU UM SAL FARMACEUTICAMENTE ACEITáVEL DO MESMO, E, COMPOSIçãO FARMACêUTICA. A invenção refere-se a uma classe de novos antagonistas para o receptor de adenosina A2 32. Estes compostos são úteis como agentes terapêuticos para várias doenças e condições médicas que são mediadas pelo receptor de A2 32. Os compostos da presente invenção são também úteis como agentes diagnósticos para o receptor de A2 32.
BRPI0606750-6A 2005-02-02 2006-02-01 composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica BRPI0606750A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64972605P 2005-02-02 2005-02-02
US11/344,295 US7435740B2 (en) 2005-02-02 2006-01-31 Adenosine A3 receptor modulators
PCT/US2006/003477 WO2006083916A2 (en) 2005-02-02 2006-02-01 Novel adenosine a3 receptor modulators

Publications (1)

Publication Number Publication Date
BRPI0606750A2 true BRPI0606750A2 (pt) 2009-07-14

Family

ID=36777854

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606750-6A BRPI0606750A2 (pt) 2005-02-02 2006-02-01 composto ou um sal farmaceuticamente aceitável do mesmo, e,composição farmacêutica

Country Status (11)

Country Link
US (1) US7435740B2 (pt)
EP (1) EP1845993A4 (pt)
JP (1) JP2008538099A (pt)
KR (1) KR20070100331A (pt)
AU (1) AU2006210817B2 (pt)
BR (1) BRPI0606750A2 (pt)
CA (1) CA2596612A1 (pt)
IL (1) IL184532A0 (pt)
MX (1) MX2007008501A (pt)
NZ (1) NZ556649A (pt)
WO (1) WO2006083916A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088403A1 (en) * 2007-05-07 2009-04-02 Randy Blakely A3 adenosine receptors as targets for the modulation of central serotonergic signaling
US8765775B2 (en) 2008-01-24 2014-07-01 Universitaet Zuerich Anti-angiogenic compounds
EP2300496A4 (en) * 2008-07-16 2012-04-25 King Pharmaceuticals Res & Dev ATHEROSCLEROSIS TREATMENT METHODS
EP2456419B1 (en) 2009-07-21 2016-11-23 Oradin Pharmaceutical Ltd. A3 adenosine receptor ligands for modulation of pigmentation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586429B2 (en) * 2000-11-29 2003-07-01 Cell Therapeutics, Inc. Tricyclic fused xanthine compounds and their uses

Also Published As

Publication number Publication date
WO2006083916A2 (en) 2006-08-10
AU2006210817A2 (en) 2006-08-10
NZ556649A (en) 2010-03-26
JP2008538099A (ja) 2008-10-09
US7435740B2 (en) 2008-10-14
US20060178385A1 (en) 2006-08-10
CA2596612A1 (en) 2006-08-10
AU2006210817A1 (en) 2006-08-10
MX2007008501A (es) 2007-09-14
AU2006210817B2 (en) 2010-12-23
WO2006083916A3 (en) 2007-12-21
EP1845993A4 (en) 2009-03-11
IL184532A0 (en) 2007-10-31
KR20070100331A (ko) 2007-10-10
EP1845993A2 (en) 2007-10-24

Similar Documents

Publication Publication Date Title
GT200800189A (es) Derivados de amida y su aplicación para el tratamiento de enfermedades relacionadas con proteína-g
BRPI0608436A2 (pt) derivados de n-(n-sulfonilaminometil) ciclopropanocarboxamida utilizáveis para o tratamento de dor
BRPI0508461B8 (pt) diaminopirimidinas, seus usos, e composição farmacêutica
BR112012028445A2 (pt) compostos de heteroarila bicíclica como moduladores de gpr119
BRPI0513433A (pt) derivados de hidantoìna para o tratamento de distúrbios inflamatórios
ATE517882T1 (de) Chinolinderivate
BR112015029512A2 (pt) derivados de pirazolopirrolidina e seu uso no tratamento de doenças
TN2009000180A1 (en) NOVEL 1,4-BENZOTHIEPIN-l,1-DIOXIDE DERIVATIVES WHICH ARE SUBSTITUTED WITH BENZYL GROUPS, METHOD FOR PRODUCING DRUGS CONTAINING SAID COMPOUNDS AND USE THEREOF
SV2011003912A (es) Moduladores de aril metil benzoquinazolinona alostericos positivos del receptor m1
EA201490489A1 (ru) Пуриновые производные и их применение в качестве модуляторов толл-подобного рецептора 7
BRPI0905687A8 (pt) composto da fórmula i ou i', composição farmacêutica, método de tratamento de um paciente com uma doença, uso do composto
BRPI0514735A (pt) derivados de piridino sulfonamida como moduladores do receptor de quimiocina
BRPI0511874A (pt) derivados da pirrolopiridina
BRPI0817096A8 (pt) Análogo de tiazolidinodiona e composição farmacêutica que o compreende
BR122019017036B8 (pt) compostos de arilamidas substituídas por tetrazol, usos dos referidos compostos e composição farmacêutica
PA8780201A1 (es) Derivados de pirasol sustituidos con heteroaril utiles para tratar trastornos hiperproliferativos y enfermedades asociadas con angiogénesis
ATE430744T1 (de) Thiazolylpiperidin-derivate nützlich als h3 rezeptor modulatoren
BRPI0720551A2 (pt) composto ou um sal farmaceuticamente aceitável do mesmo, e, uso do mesmo, método para o tratamento de câncer, processos para a preparação de uma composição farmacêutica e de um composto ou de um sal farmaceuticamente aceitável do mesmo
DOP2007000053A (es) Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo
TW200736189A (en) Indene derivatives, their preparation and use as medicaments
BRPI0507801A (pt) compostos de azetidina substituìda, processo para a preparação de compostos de azetidina substituìda, medicamento e uso de pelo menos um composto de azetidina substituìda
BRPI0821266B8 (pt) Derivados de arilamida triazol-substituída e seu uso e composição farmacêutica
EA200970065A1 (ru) Производные пиперазинила, предназначенные для лечения заболеваний, опосредованных рецептором gpr38
CL2007003289A1 (es) Compuestos derivados de biciclocarboxiamida; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de enfermedades provocadas por la hiperactivacion del receptor vc1 como dolor, enfermedad de vejiga, inflam
BRPI0706992C1 (pt) composto de fórmula (i) e formulação farmacêutica

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.