KR20070089327A - Composition for external application for skin whitening - Google Patents

Abstract

Provided is a skin whitening cosmetic composition which is able to improve or prevent skin pigmentary abnormality and hyperpigmentation and shows improved stability in formulation by maintaining an adequate level of pH using a pH buffer. The skin whitening cosmetic composition comprises 0.001-30 wt.% of a vitamin C derivative such as a water-soluble vitamin C derivative, 0.001-25 wt.% of yarrow, 0.001-25 wt.% of balm-mint, 0.001-25 wt.% of peppermint and 0.001-6 wt.% of a pH buffer, and is in the form of skin, lotion, massage cream, nutritive cream, gel, pack or skin adhesive formulation.

Description

Cosmetic composition for skin whitening {Composition for external application for skin whitening}

The present invention relates to a cosmetic composition for skin whitening which improves or prevents skin pigment abnormalities and skin pigment overdeposition and maintains the pH of the composition within a certain range to maintain stability of the main components for a long time to maintain the whitening effect. .

Melanin, which determines the color of human skin, is produced in melanocytes, which contain enzymes such as tyrosinase, and they work together to polymerize and oxidize tyrosine, an amino acid that is always present in a living body. As a result, melanin, which is a dark brown pigment, is formed. The melanin thus formed migrates to epidermal cells called keratinocytes through dendritic processes of melanocytes. Here, melanin plays an important role in forming a cap-like structure around the nucleus to protect genes from ultraviolet rays and to remove free radicals to protect intracellular proteins. There are no enzymes that degrade melanin in vivo, but they are removed from the skin along with keratinocytes as keratinocytes age, function and fall off the epidermis. However, excessive production of melanin may cause pigment hyperdeposition, such as blemishes, freckles, and spots, resulting in cosmetically bad results. In addition, as the leisure population increases, more people enjoy working outside, and the phenomenon of melanin pigmentation caused by ultraviolet rays is intensified. In addition, Asian women have long favored white and fine skin, and this is considered as an important standard of beauty. As a result, the desire for prevention and improvement of abnormal skin pigmentation and pigment overdeposition is increasing, which prevents excessive melanin production. The development of whitening agents has been necessary and many efforts have been made. Specific examples thereof include inhibitors that inhibit tyrosinase activity such as kojic acid and arbutin, hydroquinone, vitamin A and the like, and vitamin C and derivatives thereof, which are representative antioxidants. However, they are limited in their use due to their lack of safety on the skin, stability in the formulation and whitening effects.

In particular, vitamin C enhances the body's immune function, promotes the production of collagen, a component of skin, cartilage, capillaries, and muscles, and prevents skin damage by destroying chemicals generated by UV rays penetrating the skin. . It is also known as an anti-aging agent that prevents wrinkles, keeps the skin healthy, helps the healing of wounded skin tissue, and prevents the formation of histamine, which is known to cause allergic reactions, and the formation of melamine, which discolors the skin during the aging process.

However, vitamin C has a structure similar to γ-lactone, which is unstable, so that it is easily decomposed by sensitively reacting to external environments such as air, especially oxygen, heat, and light. The oxidation of vitamin C is usually a continuous two-electron transfer process, whereby the dissociation of hydrogen ions creates a dehydroascollate radical, the oxidation intermediate of vitamin C, which is reactive and itself. Reacts with two molecules to produce one molecule of vitamin C and dihydroascorbic acid. Vitamin C is very soluble in non-aqueous solution, while a large amount is dissolved in aqueous solution, but due to rapid oxidation, sufficient amount of vitamin C is not stabilized. Therefore, only a small amount of vitamin C is active in medicine, food, and cosmetics. It is reported to be usable.

Vitamin C derivatives (ascorbic acid derivatives) are used to compensate for the inherent problems of vitamin C and to improve stability. However, even if vitamin C derivatives are used, the instability of vitamin C itself tends to cause a loss of activity in the formulation, which causes inconvenience that long-term effects are difficult to sustain.

Accordingly, the present inventors have studied to solve the above problems, and as a result, it contains vitamin C derivatives, which are representative antioxidants, and herbal plant components such as yarrow, bammint and peppermint as active ingredients of whitening, and citric acid and citric acid as pH buffers. Skin topical agents have been developed that contain sodium to intentionally maintain the pH level appropriate for maintaining titer, thereby effectively preventing the degradation of vitamin C derivatives.

Accordingly, it is an object of the present invention to provide a cosmetic composition for skin whitening that is excellent in whitening effect that improves or prevents skin pigment abnormalities and skin pigment overdeposition and has significantly improved instability in the formulation.

In order to achieve the above object, the cosmetic composition for skin whitening according to the present invention is characterized by containing one or more herbal plant components selected from i) vitamin C derivatives and ii) yarrow, bammint, peppermint. The blending ratio of i) vitamin C derivative and ii) one or more herbal plant components selected from yarrow, bammint and peppermint can be appropriately adjusted by those skilled in the art within the range that can achieve an appropriate whitening effect. The blending ratio of the herbal plant component to may range from 1:30 to 30: 1. However, the compounding ratio of the vitamin derivative and the herb plant component may be varied as long as it does not depart from the object and scope of the present invention, but is not necessarily limited to the above range.

The cosmetic composition for skin whitening according to the present invention is characterized by containing a vitamin C derivative and a pH buffer. The blending ratio of the vitamin C derivative and the pH buffer may be appropriately adjusted by those skilled in the art in a range capable of maintaining an appropriate whitening effect period. For example, the blending ratio of the pH buffer to the vitamin derivative is in the range of 1:20 to 20: 1. Can be However, the compounding ratio of the vitamin derivative and the pH buffer may be varied as long as it does not depart from the object and scope of the present invention, and is not necessarily limited to the above range.

The cosmetic composition for skin whitening according to the present invention is characterized by containing i) a vitamin C derivative, ii) yarrow, iii) bammint, iv) peppermint and v) pH buffer.

In the cosmetic composition for skin whitening according to the present invention, the vitamin C derivative is characterized in that the water-soluble vitamin C derivative.

In the cosmetic composition for skin whitening according to the present invention, the water-soluble vitamin C derivative is sodium ascorbyl phosphate (SAP), magnesium ascorbyl phosphate (MAP), calcium ascorbyl phosphate ( calsium ascorbyl phosphate, ascorbic acid polypeptide, ethyl ascorbyl ether, ascorbyl dipalmitate, ascorbyl palmitate, ascorbyl palmitate (ascorbyl stearate), ascorbyl glucoside (ascorbyl glucoside) and ascorbyl ethyl silanolpectinate (ascorbyl ethyl silanolpectinate) is characterized in that at least one member selected from the group consisting of.

In the cosmetic composition for skin whitening according to the present invention, the composition is characterized in that the pH is maintained in the range of 6 to 7 using a pH buffer.

In the cosmetic composition for skin whitening according to the present invention, the pH buffer is a combination of citric acid and sodium citrate, a combination of citric acid and trisodium citrate, a combination of citric acid, sodium citrate and trisodium citrate, or lactic acid and lactic acid It is characterized by the combination of sodium.

In the cosmetic composition for skin whitening according to the present invention, yarrow is an ingredient extracted from leaves, stems, and roots of Achillea millefolium, and chestnuts are leaves, stems of Melissa Officinalis. It is extracted from the roots, peppermint is characterized in that the extract from the leaves, stems, roots of Mensa Piperita (Mentha Piperita).

i) Vitamin C derivative, ii) Yarrow, iii) Bammint, iv) Peppermint and v) pH buffer, The cosmetic composition for skin whitening according to the present invention, i) Vitamin C derivative is a total composition 0.001 to 30% by weight, ii) yarrow is 0.001 to 25% by weight relative to the total weight of the composition, iii) balm mint is 0.001 to 25% by weight relative to the total weight of the composition, and iv) peppermint is 0.001 to the total weight of the composition. To 25% by weight, v) pH buffer is characterized by containing from 0.001 to 6% by weight relative to the total weight of the composition. In the cosmetic composition for skin whitening according to the present invention, the pH buffer is citric acid and sodium citrate, citric acid is contained in 0.001 to 1% by weight based on the total weight of the composition, sodium citrate is contained in 0.001 to 5% by weight relative to the total weight of the composition It is characterized by. In addition, in the cosmetic composition for skin whitening, the remaining content of the total weight of the composition can be appropriately adjusted with a solvent, that is, alcohol or water (purified water). In the present invention, the blending ratio of each component may be appropriately selected and used by those skilled in the art in a range capable of exhibiting a suitable whitening effect in consideration of various factors such as the application range of the cosmetic composition for skin whitening, the purpose of use and economical efficiency. It is not limited or limited to the range described above.

In the cosmetic composition for skin whitening according to the present invention, the composition is characterized by having a flexible lotion, nourishing lotion, massage cream, nourishing cream, gel, pack or skin adhesive formulation.

Hereinafter, the present invention will be described in more detail.

In the cosmetic composition for skin whitening according to the present invention, the vitamin C derivative is sodium ascorbyl phosphate, magnesium ascorbyl phosphate, calcium ascorbyl phosphate, ascorbic acid polypeptide, ethyl ascorbyl ether, ascorbyl dipalmitate, It is preferable to use at least one selected from water-soluble vitamin C derivatives such as ascorbyl palmitate, ascorbyl stearate, ascorbyl glucoside and ascorbyl ethyl silanol pectinate. This is because when applied to the human body using the water-soluble vitamin C derivatives as described above, the mechanism of degradation into vitamin C by the enzyme such as phosphatase in the body is sure, so it has the effects of whitening and elasticity of vitamin C as it is. On the other hand, when oil-soluble vitamin C is used, this decomposition mechanism is uncertain and it is known to cause serious skin damage in the human body, so its use is excluded.

In the cosmetic composition for skin whitening according to the present invention, Yarrow (Western yarrow, Genus: Achilles Millefolium) and Bammint (lemon balm, Genus: Melissa Officinalis), Peppermint (Western Mint, Genus: Mensa pipepe Rita) is a herb plant with a long history, whitening by blocking the binding of endocelin 1, which is expressed in keratinocytes by stimulation of ultraviolet light to the endocelin 1 receptor of melanocytes, to lower the level of tyrosinase activation. It is known to contribute to. In addition, these herb plants are known to have a whitening effect by directly inhibiting the melanin biosynthesis mechanism of tyrosinase even when endocrine 1 binds to the endocrine 1 receptor.

Yarrow is an medicinal herb that has long been used for the treatment of many symptoms, with its anti-inflammatory effect of azulene up to 40%. In addition to wounds and inflammation of the skin, it is known to be effective in various fields such as treatment of circulatory and digestive symptoms.

Bammint is commonly called lemon balm and its active ingredients are citral, caryophyllene oxide, citronellal, eugenol acetate, geraniol and It contains 0.1 to 0.2% of volatile oils composed of the same oxidizing compound and contains a small amount of terpene hydrocarbons, tannins and flavonoids. The effect on the skin is to stop the blood in the wound and is known to be effective in fungal infections and eczema, especially in the prevention of aging.

Peppermint has a long history of high demand, contains 0.5 to 4% essential oils, 1 to 12% tannins, and small amounts of sesquiterpenes and flavonoids. It has been used for various symptoms such as headache, toothache, abdominal pain and indigestion in the East and West.

In the cosmetic composition for skin whitening according to the present invention, citric acid used as a pH buffer is pKa1 = 3.13, pKa2 = 4.76, pKa3 = 6.40, so that the pH is mixed with its salt sodium citrate or trisodium citrate and the like in the range of 6-7 It is used as a pH buffer to maintain. Thus, adjusting pH to the range of 6-7 is because the most advantageous effect in maintaining titer in this range can be acquired. Citric acid and sodium citrate are generally one of the few ingredients that can be used in cosmetics as a pH buffer, with little irritation, excellent skin safety, and widespread use in foods. It is also possible to use a combination of lactic acid and sodium lactate as the pH buffer.

In the cosmetic composition for skin whitening according to the present invention, which comprises i) a vitamin C derivative, ii) yarrow, iii) chest mint, iv) peppermint and v) pH buffer, the content of the vitamin C derivative is determined by the total weight of the composition. It is preferably from 0,001% to 30% by weight relative to. This is because the concentration is less than 0.001% by weight of the effect on the skin whitening and elasticity is less than 30% by weight it is difficult to expect further effects.

In the cosmetic composition for skin whitening according to the present invention, which comprises i) a vitamin C derivative, ii) yarrow, iii) balmmint, iv) peppermint and v) pH buffer, the content of yarrow is based on the total weight of the composition. 0.001 to 25% by weight, the content of bammint is 0.001 to 25% by weight relative to the total weight of the composition, the content of peppermint is preferably 0.001 to 25% by weight relative to the total weight of the composition. This is because the effect on the skin is less than less than 0.001% by weight, and not more than 25% by weight is not suitable as a cosmetic for reasons such as discoloration, deodorization as well as precipitation in the formulation.

In the cosmetic composition for skin whitening according to the present invention, which comprises i) a vitamin C derivative, ii) yarrow, iii) chest mint, iv) peppermint and v) pH buffer, the content of the pH buffer is determined by the total weight of the composition. It is preferably 0.001 to 6% by weight, and when the pH buffer is citric acid and sodium citrate, preferably 0.001 to 1% by weight citric acid and 0.001 to 5% by weight sodium citrate. If the content of citric acid is more than 1% by weight or the content of sodium citrate is more than 5% by weight there is a concern of skin irritation, the effect difference is small when the content of citric acid and sodium citrate is less than 0.001% by weight.

The cosmetic composition for skin whitening according to the present invention is not particularly limited in the formulation, but may be a cosmetic composition having a flexible longevity, nourishing longevity, massage cream, nourishing cream, pack, gel or skin adhesive type formulation.

Hereinafter, the present invention will be described in more detail with reference to Examples, Experimental Examples and Comparative Examples. However, the above examples are illustrated to aid the understanding of the present invention, and the scope of the present invention is not limited only to the following examples.

Example 1-4

In Table 1, HWW complexes I, II, III, and IV (Examples 1 to 4) were prepared, which consisted of vitamin C derivatives and herbal plant components. Each complex was used as a whitening effective ingredient by mixing ascorbyl glucoside, a vitamin C derivative, with yarrow, bammint and peppermint in a ratio of 1: 1 or 1: 1: 1: 1, respectively.

Item designation Ascorbyl Glucoside (Compound Ratio) Yarrow (mixing ratio) Bammint (mixed ratio) Peppermint (Compound Ratio) Example 1 HWW ComplexⅠ One One - - Example 2 HWW Complex II One - One - Example 3 HWW Complex III One - - One Example 4 HWW Complex IV One One One One

[Comparative Example 1-4]

The case where each sample of ascorbyl glucoside, yarrow, bammint, and peppermint was used individually was made into Comparative Examples 1-4, respectively.

Experimental Example 1

Melanin production inhibitory effect measurement

The melanin production inhibitory effect was measured about Examples 1-4, and the melanin production inhibitory effect was measured about Comparative Examples 1-4 as a comparative group.

HM3KO cells, human melanoma cells [Y. Funasaka, Department of dermatology, Kobe university school of medicine, Japan, Kobe, Chuo-ku, 5-chome, Kusunoki-cho 1] was put in a minimum essential medium containing 10% fetal bovine serum (Minimum Essential Medium, "MEM") was incubated under 37 ℃, 5% CO ₂ conditions. The cultured cells were spread over 75 flasks so that the number of cells was 3 × 10 ⁵ per flask, and the cells were allowed to adhere to the wall for one night. After confirming that the cells adhered well, the medium was tested in Table 1 (Examples 1 to 3). 4) and Comparative Examples 1 to 4 were changed to a fresh medium containing 10 ppm. As a control, a medium containing DMSO was used. In this way, every two to three days, the cells were changed to fresh medium containing samples, and the cells were incubated until the flask was filled. After the growth of the cells, the culture solution was removed, washed with PBS and dissolved with 1N sodium hydroxide to measure the absorbance at 500 nm and calculated the inhibition rate of melanin production according to Equation 1 shown in Table 2 below.

Melanin inhibition rate (%) = 100 ㅡ (absorbance of each test substance / absorbance of the control × 100)

Item Test substance Melanin production inhibition rate (%) Comparative Example 1 Ascorbylglucoside 20.1 Comparative Example 2 Yarrow 5.5 Comparative Example 3 Bammint 7.5 Comparative Example 4 Peppermint 7.9 Example 1 HWW Complex I (ascorbylglucoside: yarrow = 1: 1) 23.3 Example 2 HWW Complex II (ascorbylglucoside: balm mint = 1: 1) 26.7 Example 3 HWW Complex III (ascorbylglucoside: peppermint = 1: 1) 26.0 Example 4 HWW Complex IV (Ascorbylglucoside: Yarrow: Balm Mint: Peppermint = 1: 1: 1: 1) 29.8

As shown in Table 2, the HWW composites I, II, III, and IV (Examples 1 to 4) were used as compared to the case where each sample was used separately (Comparative Examples 1 to 4), and the whitening effect was excellent. In particular, the HWW complex IV (Example 4), that is, the combination of all the herbal plant components as the whitening active ingredient showed the best whitening effect.

Experimental Example 2

Evaluation of Whitening Effect at Animal Level

Brown morphot (Tortoiseshell guinea pigs; Brown guinea pigs) is an animal that causes pigmentation due to ultraviolet rays, PUVA, and allergic reactions like humans. If you choose a uniform, brown color, you can use a wide range of areas after removing the hair. Pigmentation is produced by the method enumerated below, and the improvement effect of pigmentation can be verified by the method of apply | coating the whitening composition to the pigmentation site | part. In addition, substances whose effects have been recognized by this method are useful in primary in vivo screening methods because they have a high probability of having an effect on evaluation in human ultraviolet pigmented plaques.

1) How to make UV pigment

Preparation of pigmentation by ultraviolet (UVB) was performed by bonding a light shielding aluminum foil having 6 square windows of 3x3 cm ^{2 to} the skin from which the hairs behind the brown malmot were removed, followed by an SE lamp (wavelength 290-320 nm, TOSHIBA). By irradiation with ultraviolet (UVB) light (total amount of irradiation energy is 1350 mJ / cm ² ). After irradiation, the aluminum foil was peeled off and the whitening effect of the test substance was evaluated by the application method as follows. Pigmentation after UV irradiation appears 2-3 days later, reaching peak after about 2 weeks. It is important that the resulting UV pigments have the same color tone and that no stains occur. Individuals with poor UV pigment formations should not be used for good results.

2) Coating method of composition

After UV irradiation, the composition of Table 3 (the whitening composition of the same composition as in Example 4) was started to be applied about 14 days after the pigmentation was the highest, that is, the pigmentation was formed. In addition, kojic acid was applied as Comparative Example 5. The application number of times was continued for 50 days once or twice a day. The composition was prepared by dissolving and diluting in a mixed solvent of propylene glycol: ethanol: water = 5: 3: 2, applying with a cotton swab, and applying a solvent to other sites.

ingredient Content (% by weight) Purified water to 100 Ascorbylglucoside 10 Yarrow 10 Bammint 10 Peppermint 10

3) judgment of effect

The effect was determined by measuring the degree of black and white of the skin using a color difference meter (Minolta CR2002). L * a * b * colorimeter is used for displaying a color, and in this invention, L * value (brightness) was mainly used as an index. The L * value is calibrated with a standard whiteboard, and the measurement is measured evenly on the pigment deposit by repeating the measurement five times or more at one site. The difference between the skin color (ΔL *) at the start and completion of the application was calculated according to the following Equation 2, which is shown in Table 4. The whitening effect is determined by comparing ΔL * between the sample application site and the control site. When the ΔL * value is about 2, the whitening effect of the deposited pigment is apparent, and when the degree is about 1.5 or more, the whitening effect may be determined.

L * = L * value 50 days after application-L * value at the start of application

Item Material Treatment Concentration (%) Whitening Effect (ΔL) Example 5A Whitening Composition 1.0% 1.99 Example 5B Whitening composition 0.5% 1.52 Example 5C Whitening composition 0.1% 1.03 Comparative Example 5 Kojic acid 1.0% 0.75 Control - 0.78

From the results of Table 4, it can be seen that the composition of this Example 5 had a clear whitening of pigments deposited at a concentration of 1.0% (Example 5A) and a whitening effect even at a concentration of 0.1% (Example 5C). In the case of kojic acid of Example 5, the pigment of the red group of the experimental animal was deposited, which resulted in the effect being halved. As a result of observing the effect of the cumulative irritation on the composition of Example 5 together with the above determination of the effect there was no particular stimulus.

Example 6 and Comparative Example 6

Next, HWW composites V (Example 6) and VI (Comparative Example 6) were prepared to have a pH of 6 to 7 immediately after preparation with the ingredients and contents (wt%) of Table 5, and the pH immediately after preparation thereof was also shown.

Sample composition Example 6 Comparative Example 6 Purified water to 100 to 100 Ascorbylglucoside 20% 20% Potassium hydroxide 3.7% 3.7% Citric acid 0.2% - Sodium citrate 3.0% - PH immediately after manufacture 6.77 6.60

Experimental Example 3

Changes in pH of the formulation and thus titer of vitamin C derivatives

Example 6 and Comparative Example 6 were stored in a dark condition at room temperature, 45 ° C. and 5 ° C., respectively, and after 12 weeks, the pH and titer of the first vitamin C derivatives were set to 100. It was.

Metric Example 6 Comparative Example 6 Room temperature 45 ℃ 5 ℃ Room temperature 45 ℃ 5 ℃ pH 6.21 5.98 6.17 5.66 5.21 5.94 Titer 99.2 96.8 100 96.5 87.8 98.5

From the results of Table 6, the case where the pH fluctuation range was reduced by using citric acid and sodium citrate as the pH buffer as in Example 6, compared to the case where no pH buffer was used as in Comparative Example 6 to maintain the titer of the vitamin C derivative It can be seen that there is an advantage.

Preparation Example 1-3 and Comparative Production Example 1-6

In order to test the whitening effect on the human skin, raw materials 1 to 12 were mixed and dissolved according to the ingredients and contents (wt%) of Table 7 to form water parts, while raw materials 13 to 17 were dissolved at 50 ° C. for alcohol parts. It was set as. The alcohol part was added to the water part and mixed by stirring with an Agi mixer. After removing the bubbles, it is used as Preparation Examples 1 to 3 and Comparative Preparation Examples 1 to 6.

ingredient Production Example Comparative Production Example One 2 3 One 2 3 4 5 6 1.Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 to 100 2.dipropylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 3. Butylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 4.Biosakarite Gum-1 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5 Ascorbyl Glucoside 2.0 2.0 2.0 2.0 - - - - - 6.Yarrow 0.5 0.5 - - 0.5 - - - - 7.Bammint 0.5 0.5 - - - 0.5 - - - 8 peppermint 0.5 0.5 - - - - 0.5 - - 9.kojic acid - - - - - - - - 1.0 10.citric acid 0.02 - 0.02 - - - - 0.02 - 11.Sodium Citrate 0.3 - 0.3 - - - - 0.3 - 12.Potassium hydroxide 0.37 0.37 0.37 0.37 0.37 0.37 0.37 0.37 0.37 13.ethanol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 5.0 14.phenyltrimethicone 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 15.Polyoxyethylene Hydrogenated Castor Oil 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 16.preservatives Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity 17. Incense Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity

Experimental Example 4

Whitening effect test on human skin

Twelve healthy men were placed with opaque tape with six 1.5cm diameter holes in the upper forearm area of the subject, followed by 1.5-2 times the UVB of the Minimal Erythema Dose. The blackening of the skin was induced by irradiating and the test materials were applied and two months later, the contrast of the skin was measured using a color difference meter. Each test substance was applied to the skin preparations of Preparation Examples 1 to 3 and Comparative Preparation Examples 1 to 6 twice daily in the morning and evening.

Judgment of the effect was determined by obtaining the "L" value representing the darkness of the skin as in the animal test (unburned Korean skin color generally shows a value of 50 to 70).

When the test substance is effective, the L value is gradually increased, and the comparison between the test substances calculates the difference (ΔL) of the skin color between the start point and the end point of the application according to Equation 2, and the table 8 is shown.

Test substance Whitening effect (ΔL) Preparation Example 1 3.55 Preparation Example 2 3.04 Preparation Example 3 2.82 Comparative Production Example 1 2.10 Comparative Production Example 2 1.67 Comparative Production Example 3 1.82 Comparative Production Example 4 1.79 Comparative Production Example 5 1.20 Comparative Production Example 6 2.01 Control 1.27

As can be seen in Table 8 above, when ascorbyl glucoside, yarrow, bammint, peppermint, pH buffer, kojic acid is used alone (comparative preparation examples 1 to 6) than when vitamin C derivatives and herbal plant components are combined (Preparation Examples 1 and 2) and the combination of the vitamin C derivatives and the pH buffer (Preparation Example 3) showed that the whitening effect was enhanced, especially when all the vitamin C derivatives, herbal plant components and pH buffers are used together It was observed that the maximum whitening effect was observed in (Production Example 1).

As described above, the composition according to the present invention can obtain an excellent whitening effect by using a combination of the representative antioxidant vitamin C derivatives and herbal plant extracts yarrow, bammint, peppermint, and also the pH buffering system by citric acid and sodium citrate By utilizing it, stabilization of vitamin C derivatives can be achieved to maintain the whitening effect for a longer period of time.

Claims (11)

A cosmetic composition for skin whitening comprising i) a vitamin C derivative and ii) at least one herb plant component selected from yarrow, bammint and peppermint. A cosmetic composition for skin whitening comprising a vitamin C derivative and a pH buffer. A cosmetic composition for skin whitening, comprising i) a vitamin C derivative, ii) yarrow, iii) bammint, iv) peppermint and v) pH buffer. The cosmetic composition for skin whitening according to any one of claims 1 to 3, wherein the vitamin C derivative is a water-soluble vitamin C derivative. The method of claim 4, wherein the water-soluble vitamin C derivative is sodium ascorbyl phosphate, magnesium ascorbyl phosphate, calcium ascorbyl phosphate, ascorbic acid polypeptide, ethyl ascorbyl ether, ascorbyl dipalmitate, ascorbyl palmitate And at least one member selected from the group consisting of ascorbyl stearate, ascorbyl glucoside, and ascorbyl ethyl silanol pectinate. The cosmetic composition for skin whitening according to any one of claims 1 to 3, wherein the composition maintains a pH in a range of 6 to 7 using a pH buffer. 7. The method according to claim 6, wherein the pH buffer is a combination of citric acid and sodium citrate, a combination of citric acid and trisodium citrate, a combination of citric acid, sodium citrate and trisodium citrate, or a combination of lactic acid and sodium lactate. A cosmetic composition for skin whitening. According to claim 1 or claim 3, Yarrow is an ingredient extracted from the leaves, stems, roots of the Achilles millefolium, Bhammint is an ingredient extracted from the leaves, stems, roots of Melissa Officinalis, Peppermint is Mensa Cosmetic composition for skin whitening, characterized in that the components extracted from the leaves, stems, roots of piperita. The method of claim 3, wherein i) the vitamin C derivative is 0.001 to 30% by weight relative to the total weight of the composition, ii) yarrow is 0.001 to 25% by weight relative to the total weight of the composition, and iii) balm mint is 0.001 to 30% by weight of the total weight of the composition. 25% by weight, iv) peppermint is 0.001 to 25% by weight relative to the total weight of the composition, v) pH buffer agent is 0.001 to 6% by weight based on the total weight of the composition. The skin of claim 9, wherein the pH buffer is citric acid and sodium citrate, and citrate is contained in an amount of 0.001 to 1% by weight based on the total weight of the composition, and sodium citrate in an amount of 0.001 to 5% by weight based on the total weight of the composition. Whitening cosmetic composition. The cosmetic composition for skin whitening according to any one of claims 1 to 3, wherein the composition has a flexible lotion, a nourishing lotion, a massage cream, a nourishing cream, a gel, a pack, or a skin adhesive formulation.