KR20070027649A - 안구내의 상의 질의 개선 방법 - Google Patents
안구내의 상의 질의 개선 방법 Download PDFInfo
- Publication number
- KR20070027649A KR20070027649A KR1020067027745A KR20067027745A KR20070027649A KR 20070027649 A KR20070027649 A KR 20070027649A KR 1020067027745 A KR1020067027745 A KR 1020067027745A KR 20067027745 A KR20067027745 A KR 20067027745A KR 20070027649 A KR20070027649 A KR 20070027649A
- Authority
- KR
- South Korea
- Prior art keywords
- lutein
- zeaxanthin
- body weight
- quality
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000000744 eyelid Anatomy 0.000 title 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 claims abstract description 34
- 239000000203 mixture Substances 0.000 claims abstract description 21
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 claims abstract description 18
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 claims abstract description 18
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 claims abstract description 18
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 claims abstract description 18
- 235000010930 zeaxanthin Nutrition 0.000 claims abstract description 18
- 239000001775 zeaxanthin Substances 0.000 claims abstract description 18
- 229940043269 zeaxanthin Drugs 0.000 claims abstract description 18
- 235000012680 lutein Nutrition 0.000 claims abstract description 16
- 239000001656 lutein Substances 0.000 claims abstract description 16
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims abstract description 16
- 229960005375 lutein Drugs 0.000 claims abstract description 16
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 claims abstract description 16
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 claims abstract description 16
- 238000002360 preparation method Methods 0.000 claims abstract description 3
- 230000004075 alteration Effects 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 16
- 230000037396 body weight Effects 0.000 claims description 10
- 235000013361 beverage Nutrition 0.000 claims description 3
- 235000015872 dietary supplement Nutrition 0.000 claims description 3
- 235000013305 food Nutrition 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- 210000001508 eye Anatomy 0.000 description 17
- 239000004615 ingredient Substances 0.000 description 9
- 239000007903 gelatin capsule Substances 0.000 description 8
- 238000009472 formulation Methods 0.000 description 4
- 210000001525 retina Anatomy 0.000 description 4
- 201000009310 astigmatism Diseases 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 206010010071 Coma Diseases 0.000 description 2
- 206010020675 Hypermetropia Diseases 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000005252 bulbus oculi Anatomy 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 201000006318 hyperopia Diseases 0.000 description 2
- 230000004305 hyperopia Effects 0.000 description 2
- 208000001491 myopia Diseases 0.000 description 2
- 230000004379 myopia Effects 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000004256 retinal image Effects 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 229920001938 Vegetable gum Polymers 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 235000012970 cakes Nutrition 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000014510 cooky Nutrition 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007938 effervescent tablet Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000007887 hard shell capsule Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 235000015122 lemonade Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000012669 liquid formulation Substances 0.000 description 1
- 229940111542 lutein 10 mg Drugs 0.000 description 1
- 229940070533 lutein 20 mg Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000007886 soft shell capsule Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Eye Examination Apparatus (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04015189 | 2004-06-29 | ||
| EP04015189.6 | 2004-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20070027649A true KR20070027649A (ko) | 2007-03-09 |
Family
ID=35782481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020067027745A Ceased KR20070027649A (ko) | 2004-06-29 | 2005-06-08 | 안구내의 상의 질의 개선 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20080045605A1 (enExample) |
| EP (1) | EP1761254B1 (enExample) |
| JP (1) | JP5074184B2 (enExample) |
| KR (1) | KR20070027649A (enExample) |
| CN (1) | CN101094666B (enExample) |
| AT (1) | ATE441406T1 (enExample) |
| DE (1) | DE602005016405D1 (enExample) |
| ES (1) | ES2331083T3 (enExample) |
| WO (1) | WO2006002735A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006084687A1 (en) * | 2005-02-11 | 2006-08-17 | Dsm Ip Assets B.V. | Use of zeaxanthin for the treatment of diseases of the peripheral retina |
| AT503329A1 (de) | 2006-03-02 | 2007-09-15 | Omnica Gmbh | Verfahren zur herstellung einer zusammensetzung, welche zumindest ein xantophyll enthält |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218436B1 (en) * | 1993-06-28 | 2001-04-17 | The Howard Foundation | Pharmaceutically active carotenoids |
| US5382714A (en) * | 1994-03-17 | 1995-01-17 | The Catholic University Of America | Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof |
| US5827652A (en) * | 1995-10-31 | 1998-10-27 | Applied Food Biotechnology, Inc. | Zeaxanthin formulations for human ingestion |
| FR2749758B1 (fr) * | 1996-06-12 | 1998-08-07 | Oenobiol Sa Lab | Composition a activite bronzante et photoprotectrice et ses applications esthetiques |
| WO1997048388A1 (en) * | 1996-06-17 | 1997-12-24 | The Board Of Trustees Of The University Of Illinois | Method of retarding and ameliorating central nervous system and eye damage |
| US6075058A (en) * | 1998-12-12 | 2000-06-13 | Tufts University | Compositions for increased bioavailability of carotenoids |
| US6712466B2 (en) * | 2001-10-25 | 2004-03-30 | Ophthonix, Inc. | Eyeglass manufacturing method using variable index layer |
| US20050032914A1 (en) * | 2002-01-30 | 2005-02-10 | Felix Barker | Lutein/zeaxanthin for glare protection |
| CN1481804A (zh) * | 2002-12-17 | 2004-03-17 | 无锡杰西医药科技有限公司 | 防治白内障、黄斑变性等眼病的配方及其使用方法 |
-
2005
- 2005-06-08 US US11/629,997 patent/US20080045605A1/en not_active Abandoned
- 2005-06-08 EP EP05759460A patent/EP1761254B1/en not_active Expired - Lifetime
- 2005-06-08 JP JP2007519638A patent/JP5074184B2/ja not_active Expired - Fee Related
- 2005-06-08 ES ES05759460T patent/ES2331083T3/es not_active Expired - Lifetime
- 2005-06-08 WO PCT/EP2005/006168 patent/WO2006002735A1/en not_active Ceased
- 2005-06-08 KR KR1020067027745A patent/KR20070027649A/ko not_active Ceased
- 2005-06-08 DE DE602005016405T patent/DE602005016405D1/de not_active Expired - Lifetime
- 2005-06-08 AT AT05759460T patent/ATE441406T1/de not_active IP Right Cessation
- 2005-06-08 CN CN2005800202695A patent/CN101094666B/zh not_active Expired - Fee Related
-
2011
- 2011-03-23 US US13/064,404 patent/US20110172313A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008505137A (ja) | 2008-02-21 |
| DE602005016405D1 (de) | 2009-10-15 |
| US20080045605A1 (en) | 2008-02-21 |
| JP5074184B2 (ja) | 2012-11-14 |
| ES2331083T3 (es) | 2009-12-21 |
| EP1761254B1 (en) | 2009-09-02 |
| CN101094666B (zh) | 2010-09-29 |
| EP1761254A1 (en) | 2007-03-14 |
| CN101094666A (zh) | 2007-12-26 |
| WO2006002735A1 (en) | 2006-01-12 |
| ATE441406T1 (de) | 2009-09-15 |
| US20110172313A1 (en) | 2011-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20061228 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20100608 Comment text: Request for Examination of Application |
|
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20111221 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20121127 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20111221 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |