KR20060131016A - 독활 추출물을 포함하는 염증 및 알러지 질환의 예방 또는치료용 조성물 - Google Patents
독활 추출물을 포함하는 염증 및 알러지 질환의 예방 또는치료용 조성물 Download PDFInfo
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- KR20060131016A KR20060131016A KR1020050050831A KR20050050831A KR20060131016A KR 20060131016 A KR20060131016 A KR 20060131016A KR 1020050050831 A KR1020050050831 A KR 1020050050831A KR 20050050831 A KR20050050831 A KR 20050050831A KR 20060131016 A KR20060131016 A KR 20060131016A
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- extract
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- inflammation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
Description
Group | Dose (mg/kg) | Ear thickness increased (mm) | % inhibition |
크로톤 오일 | 0.192 ± 0.021 | - | |
독활 추출물 | 10 | 0.201 ± 0.044 | - |
독활 추출물 | 50 | 0.181 ± 0.036 | 0.5 |
독활 추출물 | 250 | 0.130 ± 0.022* | 32.3 |
프레드니솔론 | 10 | 0.105 ± 0.014* | 45.3 |
수치는 평균 ± 표준편차를 나타낸다. * : P <0.05에서 크로톤 오일 처리군과 현격한 차이가 있는 것 |
Group | Dose (mg/kg) | Ear thickness increased (mm) | % inhibition |
TPA | 0.155 ± 0.020 | - | |
독활 추출물 | 10 | 0.148 ± 0.032 | 4.5 |
독활 추출물 | 50 | 0.120 ± 0.022 | 22.6 |
독활 추출물 | 250 | 0.098 ± 0.024* | 36.3 |
프레드니솔론 | 10 | 0.087 ± 0.019* | 43.7 |
수치는 평균 ± 표준편차를 나타낸다. * : P <0.05에서 포볼 미리스테이트 아세테이트 처리군과 현격한 차이가 있는 것 |
Claims (6)
- 독활 (Aralia cordata Thunb) 추출물을 유효성분으로 포함하는 염증 및 알러지 질환의 예방 및 치료용 약학조성물.
- 제 1항에 있어서, 상기 추출물은 물, 메탄올, 에탄올 등과 같은 극성용매 및 이들의 혼합용매에 가용한 추출물인 약학조성물.
- 제 1항에 있어서, 상기 염증 및 알러지성 질환은 급, 만성 염증질환, 기관지천식, 알러지성 비염, 알러지성 천식 및 알러지성 피부염인 약학조성물.
- 제 1항 내지 3항 중 어느 한 항에 있어서, 조성물 총 중량에 대하여 상기 추출물을 0.01 ~ 50 % 포함하는 약학조성물.
- 염증 및 알러지성 질환의 예방 및 개선 효과를 나타내는 독활 (Aralia cordata Thunb) 추출물 및 식품학적으로 허용 가능한 식품보조 첨가제를 포함하는 건강보조식품.
- 제 5항에 있어서, 분말, 과립, 정제, 캡슐 또는 음료인 형태인 건강보조식품.
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KR1020050050831A KR100825432B1 (ko) | 2005-06-14 | 2005-06-14 | 독활 추출물을 포함하는 염증 및 알러지 질환의 예방 또는치료용 조성물 |
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KR1020050050831A KR100825432B1 (ko) | 2005-06-14 | 2005-06-14 | 독활 추출물을 포함하는 염증 및 알러지 질환의 예방 또는치료용 조성물 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008069604A1 (en) * | 2006-12-08 | 2008-06-12 | Whan In Pharm Co., Ltd | Composition comprising the mixed herbal extract of aralia cordata thunb. and cimicifuga heracleifolia kom. for preventing and treating inflammatory disease and pain disease |
KR100900343B1 (ko) * | 2007-07-05 | 2009-06-02 | 조선대학교산학협력단 | 세포 독성 개선 및 간손상 억제 활성을 갖는 독활 추출물을함유하는 간질환의 예방 및 치료용 조성물 |
WO2012165843A3 (ko) * | 2011-05-30 | 2013-03-28 | 한국 한의학 연구원 | 생약 추출물 또는 이의 유산균 발효물을 포함하는 호흡기 질환의 예방 또는 치료용 조성물 |
WO2017095146A1 (ko) * | 2015-11-30 | 2017-06-08 | 주식회사 아모레퍼시픽 | 아랄로시드를 함유하는 피부 외용제 조성물 |
KR102209883B1 (ko) * | 2020-06-12 | 2021-02-02 | (주)오성내츄럴바이오 | 비염 완화 또는 치료용 생약 조성물 |
-
2005
- 2005-06-14 KR KR1020050050831A patent/KR100825432B1/ko active IP Right Grant
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008069604A1 (en) * | 2006-12-08 | 2008-06-12 | Whan In Pharm Co., Ltd | Composition comprising the mixed herbal extract of aralia cordata thunb. and cimicifuga heracleifolia kom. for preventing and treating inflammatory disease and pain disease |
KR100900343B1 (ko) * | 2007-07-05 | 2009-06-02 | 조선대학교산학협력단 | 세포 독성 개선 및 간손상 억제 활성을 갖는 독활 추출물을함유하는 간질환의 예방 및 치료용 조성물 |
WO2012165843A3 (ko) * | 2011-05-30 | 2013-03-28 | 한국 한의학 연구원 | 생약 추출물 또는 이의 유산균 발효물을 포함하는 호흡기 질환의 예방 또는 치료용 조성물 |
US9125932B2 (en) | 2011-05-30 | 2015-09-08 | Korea Institute Of Oriental Medicine | Composition comprising herbal extracts or fermented products thereof having lactic acid bacteria for preventing or treating respiratory diseases |
WO2017095146A1 (ko) * | 2015-11-30 | 2017-06-08 | 주식회사 아모레퍼시픽 | 아랄로시드를 함유하는 피부 외용제 조성물 |
US11052098B2 (en) | 2015-11-30 | 2021-07-06 | Amorepacific Corporation | Composition containing araloside for external application to skin |
KR102209883B1 (ko) * | 2020-06-12 | 2021-02-02 | (주)오성내츄럴바이오 | 비염 완화 또는 치료용 생약 조성물 |
WO2021251617A1 (ko) * | 2020-06-12 | 2021-12-16 | (주)오성내츄럴바이오 | 비염 완화 또는 치료용 생약 조성물, 이를 포함하는 한방 약침액, 이를 포함하는 주사제 및 이를 이용한 약침 침술방법 |
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