KR20050108420A - Ｃ형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물 - Google Patents

Ｃ형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물 Download PDF

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Publication number
KR20050108420A
KR20050108420A KR1020057018703A KR20057018703A KR20050108420A KR 20050108420 A KR20050108420 A KR 20050108420A KR 1020057018703 A KR1020057018703 A KR 1020057018703A KR 20057018703 A KR20057018703 A KR 20057018703A KR 20050108420 A KR20050108420 A KR 20050108420A
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KR
South Korea
Prior art keywords
pharmaceutically acceptable
alkyl
weight percent
formula
pharmaceutical composition
Prior art date
Application number
KR1020057018703A
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English (en)
Korean (ko)
Inventor
셜린 천
샤오후이 메이
쩌런 왕
Original Assignee
베링거 인겔하임 인터내셔날 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33310709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20050108420(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 베링거 인겔하임 인터내셔날 게엠베하 filed Critical 베링거 인겔하임 인터내셔날 게엠베하
Publication of KR20050108420A publication Critical patent/KR20050108420A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020057018703A 2003-04-02 2004-03-23 Ｃ형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물 KR20050108420A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45976503P 2003-04-02 2003-04-02
US60/459,765 2003-04-02

Publications (1)

Publication Number Publication Date
KR20050108420A true KR20050108420A (ko) 2005-11-16

Family

ID=33310709

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057018703A KR20050108420A (ko) 2003-04-02 2004-03-23 Ｃ형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물

Country Status (24)

Country Link
US (1) US7157424B2 (zh)
EP (1) EP1613353A1 (zh)
JP (1) JP2006522017A (zh)
KR (1) KR20050108420A (zh)
CN (1) CN100363055C (zh)
AR (1) AR043795A1 (zh)
AU (1) AU2004231538A1 (zh)
BR (1) BRPI0409068A (zh)
CA (1) CA2520886A1 (zh)
CO (1) CO5640152A2 (zh)
EA (1) EA010013B1 (zh)
EC (1) ECSP056065A (zh)
HK (1) HK1091130A1 (zh)
HR (1) HRP20050871A2 (zh)
MX (1) MXPA05010338A (zh)
NO (1) NO20055057L (zh)
NZ (1) NZ543250A (zh)
PE (1) PE20050013A1 (zh)
RS (1) RS20050741A (zh)
TW (1) TW200505484A (zh)
UA (1) UA81028C2 (zh)
UY (1) UY28250A1 (zh)
WO (1) WO2004093915A1 (zh)
ZA (1) ZA200506019B (zh)

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Publication number Publication date
HK1091130A1 (en) 2007-01-12
EP1613353A1 (en) 2006-01-11
UA81028C2 (en) 2007-11-26
EA200501532A1 (ru) 2006-06-30
CN1767856A (zh) 2006-05-03
JP2006522017A (ja) 2006-09-28
PE20050013A1 (es) 2005-03-01
BRPI0409068A (pt) 2006-03-28
CO5640152A2 (es) 2006-05-31
EA010013B1 (ru) 2008-06-30
CA2520886A1 (en) 2004-11-04
WO2004093915A1 (en) 2004-11-04
CN100363055C (zh) 2008-01-23
NO20055057L (no) 2005-10-31
ZA200506019B (en) 2006-07-26
NZ543250A (en) 2008-12-24
MXPA05010338A (es) 2005-11-17
ECSP056065A (es) 2006-01-27
AU2004231538A1 (en) 2004-11-04
RS20050741A (en) 2007-06-04
AR043795A1 (es) 2005-08-10
TW200505484A (en) 2005-02-16
US7157424B2 (en) 2007-01-02
US20040229776A1 (en) 2004-11-18
UY28250A1 (es) 2004-11-30
HRP20050871A2 (en) 2006-10-31

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