KR20050044861A - 리보플라빈 생산을 개선하기 위한 유전학적 균주 최적화 - Google Patents

리보플라빈 생산을 개선하기 위한 유전학적 균주 최적화 Download PDF

Info

Publication number
KR20050044861A
KR20050044861A KR1020047008485A KR20047008485A KR20050044861A KR 20050044861 A KR20050044861 A KR 20050044861A KR 1020047008485 A KR1020047008485 A KR 1020047008485A KR 20047008485 A KR20047008485 A KR 20047008485A KR 20050044861 A KR20050044861 A KR 20050044861A
Authority
KR
South Korea
Prior art keywords
leu
gly
glu
val
ala
Prior art date
Application number
KR1020047008485A
Other languages
English (en)
Korean (ko)
Inventor
헤닝 알퇴퍼
요세 엘. 레부엘타도발
Original Assignee
바스프 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바스프 악티엔게젤샤프트 filed Critical 바스프 악티엔게젤샤프트
Publication of KR20050044861A publication Critical patent/KR20050044861A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020047008485A 2001-12-04 2002-12-03 리보플라빈 생산을 개선하기 위한 유전학적 균주 최적화 KR20050044861A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10159396A DE10159396A1 (de) 2001-12-04 2001-12-04 Genetische Stammoptimierung zur verbesserten Herstellung von Riboflavin
DE10159396.1 2001-12-04

Publications (1)

Publication Number Publication Date
KR20050044861A true KR20050044861A (ko) 2005-05-13

Family

ID=7707902

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047008485A KR20050044861A (ko) 2001-12-04 2002-12-03 리보플라빈 생산을 개선하기 위한 유전학적 균주 최적화

Country Status (7)

Country Link
EP (1) EP1456388A1 (de)
JP (1) JP2005511053A (de)
KR (1) KR20050044861A (de)
CN (1) CN1599796A (de)
AU (1) AU2002358083A1 (de)
DE (1) DE10159396A1 (de)
WO (1) WO2003048367A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160059962A (ko) * 2014-11-19 2016-05-27 바스프 에스이 Rib７ 프로모터를 사용하여 유전자 발현을 하향조절하기 위한 에레모테시움의 유전적 변형

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1596125B1 (de) 2004-05-14 2008-01-09 C.R.F. Società Consortile per Azioni Einheit zur Projektion eines Lichtbündels, eine optische Vorrichtung für die Einheit, und Fahrzeug Frontlichteinrichtung
CN100430471C (zh) * 2006-05-17 2008-11-05 天津大学 产核黄素的工程菌株及其生产核黄素的方法
US8138876B2 (en) * 2008-01-29 2012-03-20 International Business Machines Corporation On-chip integrated voltage-controlled variable inductor, methods of making and tuning such variable inductors, and design structures integrating such variable inductors
CN102809658A (zh) * 2012-09-03 2012-12-05 南开大学 一种维生素b2的酶联免疫检测试剂盒
CN107109424A (zh) * 2014-12-01 2017-08-29 丹尼斯科美国公司 真菌宿主菌株、dna构建体及使用方法
CN114592000B (zh) * 2020-12-03 2023-07-21 上海市农业科学院 一种六基因组合在水稻种子中提高vb2含量的应用及方法
CN113817654B (zh) * 2021-11-08 2023-06-20 通辽梅花生物科技有限公司 一种生产核黄素的发酵培养基及发酵方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1066486C (zh) * 1989-06-22 2001-05-30 霍夫曼-拉罗奇有限公司 高产核黄素的细菌菌株
ES2216010T3 (es) * 1994-03-25 2004-10-16 Basf Aktiengesellschaft Biosintesis de riboflavina en hongos.
DE19823834A1 (de) * 1998-05-28 1999-12-02 Basf Ag Genetisches Verfahren zur Herstellung von Riboflavin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160059962A (ko) * 2014-11-19 2016-05-27 바스프 에스이 Rib７ 프로모터를 사용하여 유전자 발현을 하향조절하기 위한 에레모테시움의 유전적 변형

Also Published As

Publication number Publication date
CN1599796A (zh) 2005-03-23
WO2003048367A1 (de) 2003-06-12
AU2002358083A1 (en) 2003-06-17
DE10159396A1 (de) 2003-06-12
EP1456388A1 (de) 2004-09-15
JP2005511053A (ja) 2005-04-28

Similar Documents

Publication Publication Date Title
KR20010043867A (ko) 리보플라빈을 생산하는 유전적 방법
US11299522B2 (en) Method of producing proteins in filamentous fungi with decreased CLR2 activity
KR20050044861A (ko) 리보플라빈 생산을 개선하기 위한 유전학적 균주 최적화
Gombert et al. Functional characterization of the oxaloacetase encoding gene and elimination of oxalate formation in the β-lactam producer Penicillium chrysogenum
US7041471B1 (en) Carotene hydroxylase and method for producing xanthophyll derivatives
US10597429B2 (en) Method of producing proteins in filamentous fungi with decreased CLR1 activity
AU778297B2 (en) Fatty acid desaturase gene from plants
JP2005511053A6 (ja) リボフラビンの産生改善のための遺伝的系統の最適化
CA2477849A1 (en) Method for producing riboflavin
JP2006075168A (ja) ハロゲナーゼを含有する核酸断片およびベクター、ならびに化合物のハロゲン化方法
US20050166271A1 (en) Fatty acid desaturase gene obtained from pomegranate and method for the production of unsaturated fatty acids
US9206450B2 (en) Enhanced citric acid production in aspergillus with inactivated asparagine-linked glycosylation protein 3 (ALG3), and/or increased laeA expression
US20160046967A1 (en) Enhanced itaconic acid production in aspergillus with increased laea expression
US20050239161A1 (en) Genetic strain optimization for improving the production of riboflavin
US20140134685A1 (en) Method to increase algal biomass and enhance its quality for the production of fuel
CN105603034B (zh) 使用rib7启动子下调基因表达的假囊酵母属的遗传修饰
JP2002509725A (ja) Ｐｏｐｓ−ヒドロキシル化率の増大方法

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid