KR20050029245A - Discharge member and container provided with the same - Google Patents

Abstract

A discharge member from which liquid filled in a flexible container is discharged by pressing the container and a container provided with the discharge member on a mouth portion of the container are disclosed. The discharge member comprises a discharge portion with a substantially cylinder-like or substantially bowl-like form provided with a discharge hole in the bottom; a valve body formed of an elastic body which valve body closes the discharge hole and/or a flow passage in the discharge portion connected to the discharge hole when the valve body is not subjected to liquid pressure and opens the discharge hole and/or the passage when the valve body is deformed by liquid pressure; and an air vent connected to the discharge hole and the flow passage through an air-vent filter. The valve body can be deformed by liquid pressure that is lower than liquid passing pressure of the air- vent filter, and the discharge hole and/or the flow passage cannot be opened by passing pressure of air from outside to the air vent filter.

Description

Discharging member and a container having the same {DISCHARGE MEMBER AND CONTAINER PROVIDED WITH THE SAME}

The present invention relates to a discharge member for discharging the contents liquid filled in a flexible container by pressurizing the container, and a container provided with the discharge member.

In the container used by dropping a liquid like an eye drop container, for example, the discharge member 150 shown in Figs. 41A and 41B is used. The discharge member 150 is mounted to a mouth portion 152a of the container body 152, and the inner diameter of the discharge hole 151 can discharge the contents liquid by pressing the container body 152. In addition, when the container main body 152 is not pressurized, it is set to the magnitude | size which is not discharged, and the diameter of the discharge port 153 is set to the magnitude | size which can hold | maintain the solution liquid in the droplet state.

In the container shown in FIG. 41, there is a high possibility that microorganisms, such as bacteria, dust, and foreign matter will adhere to the discharge port 153, and especially in the case of eye drop container, the microorganism is discharged to the discharge port 153 by contact with the cornea or the eyelid. There is a very high risk of attachment. In addition, since after discharging the contents liquid from the container, the outside air is taken in from the discharge port 153 to restore the container body 152 deformed by pressure, for example, in FIGS. 42 (a) and (b). As shown, microorganisms, dust, and the like adhering to the discharge port 153 may flow back into the container main body 152 together with the contents liquid (eye drops 155) remaining in the discharge port 153. In addition, in FIG.42 (b), the code | symbol 156 shows the bubble in the internal liquid (eye drop: 155).

Since microorganisms, dust, and the like penetrate the inside of the container body, decay and deterioration of the contents are caused. For example, benzalkonium chloride, parabens, and the like as a preservative are compounded in the eye drops contained in the eye drop container. However, depending on the type of eye drops, prescription containing a preservative may be difficult, or a side effect such as an allergy may occur to eyedrop users by formulating an antiseptic. Therefore, consideration is given to avoiding the use of preservatives or to minimize the amount of the preservatives used.

For example, recently, what is called a disposable eye drop container provided by sealing only a very small amount of eye drops in a container without using a preservative is provided. According to this eye drop container, non-preservation of a preservative can be realized, but since it is cost-problem, it is limited to a specific use and is not widely used.

Japanese Laid-Open Patent Publication No. 2002-80055 discloses a discharge container with a filter employing a so-called delaminate bottle having an outer layer and an inner layer formed on the inner surface thereof so as to be peeled off. According to this discharge container, it is possible to prevent the inflow of outside air into the container from the discharge port even after discharging the liquid, and therefore, it is possible to prevent the incorporation of bacteria into the liquid. However, it is necessary to provide an easily deformable inner container constituted by the inner layer in order to cope with a change in the inner pressure of the container due to the discharge of the liquid content, and there is a problem that the manufacturing cost of the container is high.

On the other hand, Japanese Patent Application Laid-Open No. 2001-179017 or Japanese Patent Laid-Open No. 2001-206454 discloses an antimicrobial container formed by disposing a porous filter at a discharge port such that the size of the distribution hole diameter cannot pass through microorganisms or dust. have. However, if the porous filter is dried while the chemical liquid or the like is infiltrated, clogging may occur in the filter due to the solute in the chemical liquid. In particular, depending on the application, the eye drop may be a suspension, and in this case, clogging problems are more likely to occur. In the containers described in JP 2001-179017 A and JP 2001-206454 A metal sintered body, resin sintered body, and the like are used as the porous filter, in this case, fine particles of the sintered body are mixed in the chemical liquid and discharged from the container. There is also concern.

1 is a cross-sectional view showing an embodiment of the first discharge member.

2 is a cross-sectional view showing an embodiment of a container provided with a first discharge member.

3 is a cross-sectional view showing a state in which the cap of the container shown in FIG. 2 is not opened.

4 is a cross-sectional view showing a state of use of the container shown in FIG. 2.

5 is a cross-sectional view illustrating the continuation of FIG. 4.

6 is a cross-sectional view showing another embodiment of the container provided with the first discharge member.

7 is a cross-sectional view showing another embodiment of the first discharge member.

8 is a cross-sectional view showing still another embodiment of the first discharge member.

9 is a cross-sectional view showing an embodiment of the second discharge member.

FIG. 10: is sectional drawing which shows the state which disassembled the discharge member 30 shown in FIG.

11 (a) is a plan view showing an example of an integrally formed product of the discharge part main body 31a and the valve body 33, and FIG. 11 (b) is a bottom view thereof.

12 (a) is a plan view of the valve seat portion 34, and FIG. 12 (b) is a bottom view thereof.

FIG. 13 (a) is a plan view showing another example of the integrally formed article of the discharge part main body and the valve body, and FIG. 13 (b) is a plan view showing another example of the valve seat part.

FIG. 14 is a cross-sectional view showing an embodiment of a container provided with a second discharge member. FIG.

FIG. 15 is a cross-sectional view illustrating a state of use of the container illustrated in FIG. 14.

16 is a cross-sectional view illustrating the continuation of FIG. 15.

FIG. 17: is sectional drawing which shows the state which did not open the stopper of the container 40 shown in FIG.

18 is a cross-sectional view showing another embodiment of the second discharge member.

19 is a cross-sectional view showing an embodiment of the third discharge member.

FIG. 20 is an exploded cross-sectional view of the discharge member 50 shown in FIG. 19.

FIG. 21: is a top view of the discharge part main body 51a shown in FIG.

FIG.22 (a) is a top view of the valve body support member 54 shown in FIG. 20, and FIG.22 (b) is its bottom view.

FIG. 23 is an explanatory diagram showing a method of assembling the discharge member 50 shown in FIG. 19.

24 is a cross-sectional view showing an example of a container provided with the discharge member 50 of FIG. 19.

FIG. 25: is sectional drawing which shows the use condition of the container 60 shown in FIG.

FIG. 26 is a cross-sectional view illustrating the continuation of FIG. 25.

FIG. 27: is sectional drawing which shows the state which did not open the stopper of the container 60 shown in FIG.

28 is a cross-sectional view showing an embodiment of the fourth discharge member.

FIG. 29A is a bottom view of the discharge member 70 shown in FIG. 28, and FIG. 29B is an A-A cross-sectional view.

FIG. 30A is a cross-sectional view showing an example of a container provided with the fourth discharge member 70, and FIG. 30 (B) is a cross-sectional view showing its use state.

FIG. 31: is sectional drawing which shows the continuation of FIG. 30 (b).

32 is a cross-sectional view showing another embodiment of the fourth discharge member according to the present invention.

33 is a cross-sectional view showing an embodiment of the fifth discharge member.

34 is a cross-sectional view showing an embodiment of a container provided with a fifth discharge member.

(A) is sectional drawing which shows the state which attached the cap to the container 100 shown in FIG. 34, and FIG. 35 (b) is sectional drawing which shows the said cap.

FIG. 36: is sectional drawing which shows the use condition of the container shown in FIG.

FIG. 37 is a cross-sectional view illustrating the continuation of FIG. 36.

FIG. 38 is an enlarged cross-sectional view showing the discharge portion of the container 100 shown in FIG. 36B.

39 is a cross-sectional view showing another embodiment of the fifth discharge member.

FIG. 40 is an enlarged cross-sectional view of the discharge portion in the using state of the container 100 'shown in FIG. 39.

Fig. 41A is a front view showing an example of a conventional eye drop container, and Fig. 41B is an enlarged cross-sectional view of the discharge member.

It is explanatory drawing which shows the problem in the conventional eye drop container.

* Description of the sign *

10, 10 ', 10a, 10b, 30, 30', 50, 70, 70 ', 90, 90': discharge member

11, 31, 51, 71, 71 ', 91: discharge part

11d: inner surface of discharge part

12, 32, 52, 72, 92: discharge hole

13, 13a, 13b, 33, 33 ', 53, 73, 73', 93, 93 ': valve body

14: Consolidated Government

15, 35, 55, 75, 95: Euro

16, 36, 56, 76, 96: vent holes

17, 37, 57, 77, 97: Aeration filter

18, 38, 58, 78: liquid filter

20, 20 ', 40, 60, 80, 100: container (eyedropper)

21, 41, 61, 81, 101: container body

23, 43, 63, 83, 103: internal stopcock (cock)

24, 44, 64, 84, 104: contents

25, 45, 65, 85, 105: droplets

25 ', 45', 65 ', 85', 105 ': Residue

26, 46, 66, 106: cap

34a, 34a ', 74: valve seat

52a: Euro Inner Wall

52b: protrusion

53a: valve body

53b: turning

93a: thinner

93b: valve body

94a: valve body support

94b: flange

U: upstream

D: downstream

Accordingly, an object of the present invention is a member for discharging a liquid as droplets while being in the mouth of a container, and is capable of preventing reverse flow of the liquid and further aseptically introducing the air into the container after the discharging operation. To provide a member.

In addition, another object of the present invention is that it is not necessary to mix or suppress the formulation of a medicament for preventing the decay or deterioration of the contents, and even if the contents are a suspension, without causing clogging at the discharge port. It is to provide a container that can realize a smooth discharge.

[Discharge member]

The discharge member of the present invention for solving the above-mentioned problems includes a substantially cylindrical or substantially bowl-like discharge portion having a bottom having discharge holes at the bottom, and downstream of the discharge hole side. When it is set to the side, the flow path in the discharge portion connected to the discharge hole and / or the discharge hole in the state of not receiving the hydraulic pressure from the upstream side is closed, and when the hydraulic pressure is received from the upstream side, the discharge hole and / or the flow path is deformed. A valve body made of an elastic body and a vent hole connected to a flow path upstream of the valve body through a vent filter, and the deformation of the valve body is achieved by a hydraulic pressure smaller than the fluid pressure of the vent filter. And that opening of the discharge hole and / or the flow path is not achieved by the ventilation pressure from the outside to the ventilation filter. And a gong.

In the discharge member of the present invention, the valve body for controlling the closing and opening of the discharge hole and the flow path is made of an elastic body, and closes the discharge hole and / or the flow path without receiving hydraulic pressure from the upstream side, and from the upstream side. When hydraulic pressure is applied, deformation occurs to open the discharge hole and / or the flow path. When the discharge hole and / or the flow path are opened, the discharge hole and the upstream side of the discharge part (specifically, a container body such as an eye drop container connected to the discharge member of the present invention) are connected to each other, and the chemical liquid from the discharge hole Discharge can be realized.

In the discharge member of the present invention, in order to realize the discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to a container body such as an eye drop container connected to the discharge member, for example. According to this pressurization, the hydraulic pressure of the contents liquid (chemical liquid, etc.) is applied from the upstream side to the valve body of the discharge member, whereby the valve body is deformed and the discharge hole and / or the flow path are opened. On the other hand, after the discharge operation is completed, the deformed container main body tries to introduce outside air from the vent hole to restore its shape. Here, according to the discharge member of the present invention, since the vent filter is provided in the vent hole connected to the flow path of the liquid solution, it is possible to aseptically achieve the introduction of air into the container after the discharge operation.

After the discharging operation is completed, the negative pressure to introduce the outside air generated inside the container body connected to the discharging member exhibits the action of accelerating the restoration operation of the deformed valve body. Therefore, the gap (flow path) formed between the valve body and the discharge portion by the discharge operation is immediately closed by removing the pressure on the container body, and the valve body in the discharge member of the present invention functions as a check valve.

As an embodiment of the discharge member which concerns on this invention, the 1st-5th embodiment shown below is mentioned, for example.

(1st embodiment)

The 1st discharge member which concerns on this invention is arrange | positioned in the discharge part of the substantially cylindrical shape or substantially main shape which has a bottom provided with a discharge hole in the bottom part, and an upstream side when the said discharge hole side is made downstream. A valve body made of an elastic body which is closed by the discharge hole in a state in which no hydraulic pressure is applied from the cylinder and is subjected to hydraulic pressure from an upstream side, and is compressed and deformed to open the discharge hole, and is disposed inside the discharge section and has an inner surface of the discharge section. And a connection fixing portion for dividing the flow path between the flow path and the upstream side and fixing the valve body on the upstream side, and a ventilation hole connected to the flow path upstream of the valve body through the airflow filter, and compressing and deforming the valve body. The opening of the discharge hole and / or the flow path is achieved by a liquid pressure smaller than the liquid pressure of the airflow filter, and the airflow fill It is characterized by the fact that it is not achieved by aeration pressure from the outside to the rotor.

In the first discharge member, the valve body made of an elastic body disposed inside the discharge portion controls the closing and opening of the flow path using the discharge hole as the valve seat. The valve body closes the discharge hole in a state where no hydraulic pressure is received from the upstream side, and when the hydraulic pressure is received from the upstream side, it causes compression deformation and opens the discharge hole. As a result of the opening of the discharge hole, the discharge hole and a flow path partitioned between the inner surface of the discharge portion and the connection fixing portion are connected to each other, whereby discharge of the chemical liquid or the like from the discharge portion can be realized.

In the first discharge member, in order to realize the discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to the container body connected to the discharge member as described above. At the time of restoring the valve body after the end of the discharge operation, air can be flowed in aseptically from the ventilation filter, or the restoring operation of the valve body deformed by the negative pressure to introduce outside air is accelerated. Can be acted as a check valve).

In the first discharge member, since the compression deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the vent filter, liquid leakage does not occur in the vent hole during the discharge operation. Moreover, since opening of the discharge hole and / or the flow path in the discharge portion connected to the discharge hole is not achieved by the ventilation pressure from the outside to the ventilation filter, it is not from the ventilation hole but from the discharge hole when the container body is restored. The outside air does not flow in, and therefore the contents solution leaks out of the discharge hole.

Therefore, according to the first discharge member according to the present invention, the container after the discharge processing and the discharge operation can be smoothly prevented while highly preventing the reverse flow of the liquid discharged from the discharge hole and the invasion of the microorganisms and dust, etc., which follow. Can be restored.

In the first discharge member, it is preferable that the valve body and the connection fixing part are formed integrally. By integrally molding the valve body and the connection fixing part, the production process of the discharge member can be made efficient. As a method of integrally molding the valve body and the connection fixing part, for example, multi-color molding or insert molding may be mentioned.

(2nd embodiment)

The second discharge member according to the present invention includes a substantially cylindrical or substantially main-shaped discharge part having a bottom having a discharge hole at its bottom, a valve seat fixed in the discharge part, and an inner surface of the discharge part. When the discharge hole is fixed on the downstream side, in a state in which no hydraulic pressure is received from the upstream side, the flow path is brought into contact with the valve seat on the downstream side and connected to the discharge hole, and the hydraulic pressure is received from the upstream side. A substantially cylindrical valve body made of an elastic body that is deformed to open the flow path between the valve seats, and a ventilation hole connected to the flow path upstream of the valve body via a ventilation filter; Compression deformation is achieved by a hydraulic pressure smaller than the liquid pressure of the vent filter, and the discharge hole and / or the flow path It characterized in that the opening, is not achieved by the pressure tube from the outside to the vent filter.

In the second discharge member, the valve body made of an elastic body disposed inside the discharge portion is similarly paired with the valve seat portion disposed inside the discharge portion to control the closing and opening of the flow path. The valve body abuts against the valve seat in a state in which no hydraulic pressure is applied from the upstream side, and closes the flow path connecting the discharge hole and the upstream side of the discharge portion. On the other hand, when the hydraulic pressure is received from the upstream side, compression deformation occurs to form a gap between the valve seat (opening the gap with the valve seat). As a result of the formation of the gap between the valve seat, the upstream side of the valve body and the flow path of the discharge hole are connected to each other, whereby discharge of chemical liquid or the like from the discharge hole can be realized.

In the second discharge member, in order to realize the discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to the container body connected to the discharge member as described above. In restoring the valve body after the end of the discharge operation, air can be flowed in aseptically from the ventilation filter, or the restoration operation of the valve body deformed by the negative pressure to introduce outside air is accelerated. What can act as a check valve) is the same as that mentioned above.

In the second discharge member, the compressive deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the vent filter, so that no liquid leaks out of the vent hole during the discharge operation. Moreover, since opening of the discharge hole and / or the flow path in the discharge portion connected to the discharge hole is not achieved by the ventilation pressure from the outside to the ventilation filter, it is not from the ventilation hole but from the discharge hole when the container body is restored. No outside air flows in, or the contents liquid leaks out of the discharge hole.

Therefore, according to the second discharge member according to the present invention, the container after the discharge processing and the discharge operation is smoothly prevented while highly preventing the reverse flow of the liquid discharged from the discharge hole and the invasion of the microorganisms, dust, and the like accompanying thereto. Can be restored.

In the second discharge member, the valve body is fixed to the inner surface of the discharge portion from the viewpoint of strictly closing and opening the flow path. Therefore, it is not limited to this, but it is preferable to form a valve body and a discharge part by integral molding. By integrally molding the valve body and the connection fixing part, both of them can be securely fixed and the production process of the discharge member can be improved. As a method of integrally molding a valve body and a discharge part, multicolor shaping | molding and insert shaping | molding are mentioned, for example.

(Third embodiment)

The third discharge member according to the present invention is disposed in a substantially cylindrical or substantially main-shaped discharge portion having a bottom having discharge holes at a bottom thereof, and is disposed in the discharge portion and upstream when the discharge hole side is set downstream. A valve body made of an elastic body which closes the discharge hole or the flow path connected to the discharge hole in a state where no hydraulic pressure is received from the side, and expands and deforms to open the discharge hole or the flow path when the hydraulic pressure is received from the upstream side; A ventilation hole connected to a flow path upstream of the valve body via the ventilation filter, wherein the expansion and deformation of the valve body is achieved by a hydraulic pressure smaller than the liquid pressure of the ventilation filter, and the opening of the discharge hole or the flow path is opened. This is characterized in that it is not achieved by the ventilation pressure from the outside to the ventilation filter. .

In the third discharge member, the valve body made of an elastic body disposed inside the discharge portion controls the closing and opening of the discharge hole or the flow path. This valve body closes the flow path connected to the discharge hole or the discharge hole in a state where the hydraulic pressure is not received from the upstream side, and when the hydraulic pressure is received from the upstream side, elongation is deformed to open the discharge hole or the flow path. As a result of the opening of the discharge hole or the flow path, the upstream side of the valve body and the flow path of the discharge hole are connected to each other so that the discharge of the chemical liquid or the like from the discharge hole can be realized.

In the third discharge member, in order to realize the discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to the container body connected to the discharge member as described above. At the time of restoring the valve body after the end of the discharge operation, air can be flowed in aseptically from the ventilation filter, or the restoring operation of the valve body deformed by the negative pressure to introduce outside air is accelerated. Can be acted as a check valve).

In the third discharge member, the elongational deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the vent filter, so that liquid leakage does not occur in the vent hole during the discharge operation. Moreover, since such expansion deformation does not occur due to the pressure from the outside due to the structure of the valve body (therefore, even when a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, expansion deformation is not achieved), The outside air flows in from the discharge hole instead of the vent hole, and the contents liquid does not leak from the discharge hole.

Therefore, according to the third discharge member according to the present invention, the container after the discharge processing and the discharge operation can be smoothly prevented while highly preventing the reverse flow of the liquid discharged from the discharge hole and the invasion of the microorganisms and dust, etc., which follow. Can be restored.

In the third discharge member according to the present invention, the valve body has a valve body portion fixed in the flow path and a protrusion at the distal end of the discharge hole, and the protrusion at the distal end of the valve body portion is connected to the discharge hole. The protrusion formed on the inner wall of the flow path is engaged on the downstream side to close the flow path;

It is preferable that the valve main body portion extends and deforms from the upstream side to the downstream side by the hydraulic pressure to form a gap between the projection of the tip of the valve main body portion and the protruding portion on the inner wall of the flow path.

In this case, the projection at the tip of the valve body portion of the valve body is engaged from the downstream side of the protrusion formed on the inner wall of the flow passage in a state where no hydraulic pressure is applied, and the flow passage is closed. On the other hand, when the valve body is subjected to hydraulic pressure, the valve body expands and deforms downstream from the locking position, so that the flow path is opened between the projection at the tip of the valve body part and the protrusion of the flow path inner wall. After the discharge operation is completed and no hydraulic pressure is applied to the valve body, the projection of the tip of the valve body portion returns to the upstream side by restoring the valve body, so that the protrusion is engaged again with the protrusion of the inner wall of the flow path to close the flow path. As described above, the restoring operation of the valve body is accelerated by the sound pressure for introducing the outside air, which occurs when restoring the container body deformed by the ejecting operation.

(4th Embodiment)

The fourth discharge member according to the present invention is provided with a substantially cylindrical or substantially main shaped discharge portion having a bottom having discharge holes at its bottom, and abutting from the outer surface side of the discharge portion, and discharging the discharge hole side to a downstream side. The valve body is formed of an elastic body which is closed and the discharge hole is not being subjected to hydraulic pressure from the upstream side, and when the hydraulic pressure is received from the upstream side, the valve body is elongated and deformed to open the discharge hole. And a vent hole connected to the vent hole, and the expansion and deformation of the valve body is achieved by a hydraulic pressure smaller than the vent pressure of the vent filter, and the opening of the discharge hole is caused by the vent pressure from the outside to the vent filter. Characterized by not being achieved.

In the fourth discharge member, the valve body made of an elastic body that abuts against the discharge hole from the outer surface side of the discharge portion controls the closing and opening of the discharge hole. The valve body closes the discharge hole in a state in which the hydraulic pressure is not received from the upstream side, and when the hydraulic pressure is received from the upstream side, the valve body causes an elongation deformation to the outside (downstream side) of the discharge portion. ) The discharge hole is opened. As a result of the opening of the discharge hole, the upstream side of the valve body and the flow path of the discharge hole are connected to each other so that the discharge of the chemical liquid or the like from the discharge hole can be realized.

In the fourth discharge member, in order to realize discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to the container body connected to the discharge member as described above. At the time of restoring the valve body after the end of the discharge operation, air can be flowed in aseptically from the ventilation filter, or the restoring operation of the valve body deformed by the negative pressure to introduce outside air is accelerated. Can be acted as a check valve).

In the fourth discharge member, the elongational deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, so that liquid leakage does not occur in the ventilation holes during the discharge operation. Moreover, since such expansion deformation does not occur due to the pressure from the outside due to the structure of the valve body (therefore, even when a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, expansion deformation is not achieved), The outside air flows in from the discharge hole instead of the vent hole, and the contents liquid does not leak from the discharge hole.

Therefore, according to the fourth discharge member according to the present invention, the container after the discharge treatment and the discharge operation can be smoothly prevented while highly preventing the reverse flow of the liquid discharged from the discharge hole and the invasion of the microorganisms and dust, etc., which follow. Can be restored.

In the fourth discharge member according to the present invention, the discharge hole is partitioned by a substantially disk-shaped valve seat fixed in the discharge portion, and an inner wall surface of the discharge portion holding the valve seat. While having the annular thin portion, the thin portion is brought into contact with the valve seat from the outer surface side of the discharge portion to close the discharge hole. When the thin portion of the valve body has the discharge hole side downstream, It is preferable to expand and deform downstream by a hydraulic pressure, and to open the said discharge hole.

In this case, the valve body closes the discharge hole by bringing the thin part into contact with the substantially disk-shaped valve seat without being subjected to hydraulic pressure. Since the valve body expands and deforms downward (bending to the outside of the discharging portion) upon receiving the hydraulic pressure, a discharge hole partitioned between the substantially disk-shaped valve seat and the discharging portion inner wall surface holding the valve seat is opened. After the discharge operation is completed and no hydraulic pressure is applied to the valve body, the thinner portion of the valve body again comes into contact with the substantially disk-shaped valve seat, thereby closing the flow path. As described above, the restoring operation of the valve body is accelerated by the sound pressure for introducing the outside air, which occurs when restoring the container body deformed by the ejecting operation.

In the fourth discharge member according to the present invention, the valve body is preferably formed integrally with the outer side of the discharge portion. In this case, the discharge member can be produced efficiently. The method of integrally forming the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding and insert molding can be adopted.

(5th Embodiment)

The fifth discharge member according to the present invention includes a substantially cylindrical or substantially main-shaped discharge portion having a bottom having a hole at the bottom, an approximately annular valve body portion and an approximately annular thin portion formed at its tip. And a valve body made of an elastic body which is fixed to the valve body part in the discharge part in a state where the thin part is exposed from the hole out of the discharge part, and is disposed in the discharge part and discharge holes simultaneously with the valve body. And a cylinder-shaped valve body support portion formed by dividing the valve portion, and a ventilation hole connected to a flow path upstream of the valve body through a ventilation filter, when the discharge hole side is downstream. The discharge hole is closed by bringing the thin portion into contact with the outer circumferential surface of the valve body support portion without being subjected to hydraulic pressure. When the hydraulic pressure is received from the upstream side, the thin portion is elongated and deformed to open the discharge hole, and the elongated deformation of the thin portion is achieved by a hydraulic pressure smaller than the liquid pressure of the ventilation filter, and the discharge hole is opened. This is characterized in that it is not achieved by the ventilation pressure from the outside with respect to the ventilation filter.

In the fifth discharge member, the valve body made of an elastic body disposed inside the discharge portion is fixed in a state in which the thin portion is exposed from the hole formed in the bottom portion of the discharge portion to the outside of the discharge portion, and with the valve body support member. The discharge hole is partitioned in between. This thin part controls the closing and opening of a discharge hole by making the cylindrical valve body support part in a valve body support member into a valve seat. That is, the thin part of the valve body abuts against the outer circumferential surface of the valve body support part in a state where no hydraulic pressure is received from the upstream side, thereby closing the discharge hole. On the other hand, when the hydraulic pressure is received from the upstream side, the thin portion causes extension deformation to the outside (downstream side) of the discharge portion (as a result, the valve body bends to the outer peripheral side of the valve body support portion), thereby opening the discharge hole. As a result of the opening of the discharge hole, the upstream side of the valve body and the flow path of the discharge hole are connected to each other so that the discharge of the chemical liquid or the like from the discharge hole can be realized.

In the fourth discharge member, in order to realize discharge of the chemical liquid or the like from the discharge hole, pressure may be applied to the container body connected to the discharge member as described above. At the time of restoring the valve body after the end of the discharge operation, air can be flowed in aseptically from the ventilation filter, or the restoring operation of the valve body deformed by the negative pressure to introduce outside air is accelerated. Can be acted as a check valve).

In the fifth discharge member, the elongational deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the ventilation filter, so that liquid leakage does not occur in the ventilation holes during the discharge operation. Moreover, since such expansion deformation does not occur due to the pressure from the outside due to the structure of the valve body (therefore, even when a pressure equivalent to the ventilation pressure of the ventilation filter is applied from the outside, expansion deformation is not achieved), The outside air flows in from the discharge hole instead of the vent hole, and the contents liquid does not leak from the discharge hole.

Therefore, according to the fifth discharge member according to the present invention, the container after the discharge treatment and the discharge operation can be smoothly prevented while highly preventing the reverse flow of the liquid discharged from the discharge hole and the invasion of the microorganisms and dust, etc., which follow. Can be restored.

In the fifth discharge member according to the present invention, the valve body supporting portion has a flange portion upstream of the circumferential portion thereof, and the valve body portion of the valve body abuts against the flange portion without being subjected to hydraulic pressure to the flow path. It is preferable to close the and to open the flow path between the valve body support and the compressive deformation under the hydraulic pressure.

In this case, the valve body not only closes the discharge hole by bringing the thin part into contact with the outer circumferential surface of the valve body support part while the valve body is not subjected to hydraulic pressure from the upstream side, and furthermore, the valve body part is provided at the flange portion of the valve body support part. The flow path is closed by abutting. Therefore, the discharge hole can be closed more securely. On the other hand, when the valve body receives a hydraulic pressure from the upstream side, it not only causes the deformation of the thin portion to the outside (downstream side) of the discharge portion, but also compresses and deforms the valve body portion to flow between the flange portion of the valve body support portion. To form (open). As a result of the opening of the discharge hole and the flow path, the upstream side of the valve body and the flow path of the discharge hole are connected to each other so that the discharge of the chemical liquid or the like from the discharge hole can be realized.

In the fifth discharge member and a preferred embodiment thereof, the restoring operation after the discharge operation is completed and no hydraulic pressure is applied to the valve body, as described above, occurs when the container body deformed by the discharge operation is restored. It is accelerated by the sound pressure for introducing the outside air.

In the fifth discharge member according to the present invention, the valve body portion of the valve body is preferably molded so as to be integrated with the inner surface of the discharge portion. In this case, the discharge member can be produced efficiently. The method of integrally forming the valve body and the discharge portion is not particularly limited, and various methods such as multicolor molding and insert molding can be adopted.

[Antibacterial treatment]

In the discharge member according to the present invention, it is preferable that the valve body and / or the discharge hole are antibacterial. In the case where the valve body and / or the discharge hole are subjected to the antibacterial treatment, the effect of preventing the propagation of bacteria and the like can be exerted on the contents liquid (residual liquid) remaining in the vicinity of the discharge hole after completion of the discharge operation.

The object of the antibacterial treatment may be appropriately selected according to the configuration of the discharge member, and the entire discharge portion, the valve seat, the container body, the surface of the cap covering the discharge portion (in particular, the inner surface in contact with the discharge portion), and the inside of the cap. Although various site | parts, such as a water supply material (sponge, cloth, paper, hydrogel, etc.) arrange | positioned, are mentioned, It is not specifically limited.

The antibacterial treatment may be, for example, an elastic material such as thermoplastic elastomer forming a valve body or the like; Resin materials for forming discharge portions, discharge holes, valve seats, and the like; A drug such as a preservative and an antimicrobial agent is blended in advance into the material for forming the absorbent material, or the drug is applied to a surface of a preformed valve body or a discharge part by means of coating or the like, or a valve body, a discharge part, a cap, This is achieved by subjecting forming materials such as absorbents in the cap to surface treatment such as silane coupling or selenium coating. The hydrogel formed by combining a polymer such as a (meth) acrylamide system and a water-swellable clay mineral can be treated with antibacterial treatment by coating selenium on its surface.

Liquid Filter

It is preferable that the discharge member which concerns on this invention is equipped with the fluid filter upstream rather than a discharge hole, or upstream rather than the opening-closing position of the flow path by a valve body. By forming the liquid filter, even if a microorganism, dust, or the like intrudes into the liquid remaining near the discharge hole of the discharge portion, the residual liquid penetrates (backflows) to the container body connected to the discharge member. This can be suppressed or prevented. That is, it is preferable to form a liquid filter from the viewpoint of suppressing or preventing the infiltration of contaminants into the container or the like connected to the discharge member.

When the liquid passage filter is, for example, a filter having a pore diameter of about 0.2 to 0.45 mu m (small pore diameter), it becomes difficult to apply the discharge member of the present invention to a container containing a suspension. On the other hand, even if a situation in which a residual liquid containing microorganisms, dust, etc. flows back from the discharge hole, a situation in which the residual liquid penetrates (backflow) to the container body connected to the discharge member of the present invention is reliably prevented. Or can be suppressed.

In the case where the liquid passage filter is, for example, a filter having a pore diameter of about 10 to 20 µm (comparative large hole diameter), the discharge member of the present invention can be applied to a container containing a suspension. In this case, it is not necessary to consider the clogging of the liquid filter by the suspension, but rather a new effect of suppressing the precipitation of the suspension component in the vicinity of the discharge hole can be obtained. In addition, even with such a large-diameter liquid-permeable filter, it is possible to suppress passage of microorganisms to some extent, so that even if a situation in which residual liquid containing microorganisms flows back from the discharge hole occurs, the residual liquid remains in the container body. A certain effect can be obtained against suppression of intrusion (backflow) situation.

[Vessel]

The container of this invention for solving the said subject is equipped with the discharge member which concerns on this invention at the entrance part of a container main body. The container of the present invention is preferable as an eye drop container containing, for example, an eye drop.

Best Mode for Carrying Out the Invention

Next, the discharge member of this invention and the container provided with it are demonstrated in detail, referring drawings.

[First Discharge Member and Container]

As shown in FIG. 1, the 1st discharge member 10 which concerns on this invention is the discharge part of the substantially cylindrical shape (or substantially main shape) with the bottom provided with the discharge hole 12 in the bottom part ( 11) and the inside of the discharge part 11, and closes the discharge hole 12 in the state which is not receiving hydraulic pressure from the upstream side U, and receives a hydraulic pressure from the upstream side U, it compresses and deforms | discharges a discharge hole The flow path 15 is partitioned between the valve body 13 which opens the 12 and the inner surface 11d of the discharge part 11 and arranged inside the discharge part 11, and the valve body at the upstream side U. The connection fixing part 14 which fixes the 13 is provided, and the ventilation hole 16 connected to the flow path upstream rather than the valve body 13 through the ventilation filter 17 is provided.

Although the discharge hole 12 is normally closed by the valve body 13, when a hydraulic pressure is applied to the valve body 13 from the upstream side U via the flow path 15, it will apply to the said valve body 13; Compression deformation occurs, and a space | gap arises between the discharge hole 12 of the discharge part 11, and the valve body 13. As shown in FIG. Thereby, the liquid content can be discharged through the gap.

The valve body 13 is fixed in the discharge member 10 by the connection fixing portion 14, and the connection fixing portion 14 and the inner surface 11d of the discharge portion are connected to a flow path 15 such as a chemical liquid. It is.

The discharge part 11 needs to arrange the ventilation filter 17 in the ventilation hole 16, and it is arrange | positioned in the discharge part main body 11a provided with the discharge hole 12, and the upstream side U. It consists of two members of the connecting part llb connected to an entrance part, such as a chemical liquid container. The discharge part main body 11a and the connection part 11b are integrated by the joining means, such as ultrasonic bonding, in the state which pinched | interposed the ventilation filter 17 in the connection part 11c.

For example, as shown in FIG. 2, the 1st discharge member 10 can be used by attaching to the entrance part of the container main body 2l. In the container 20 shown in FIG. 2, the discharge member 10 is attached to the neck portion 22 of the container 20 via an inner stopper 23. As shown in FIG. 2 and FIG. 3, the inner stopper 23 slides freely into the neck portion 22 of the container 20, and FIG. 2 is a cross section in the use state of the container 20. 3 shows a cross-sectional view in a state where the stopper of the container 20 is not opened.

In the state in which the stopper shown in FIG. 3 is not opened, not only the cap 26 is attached to the discharge part 11 but also the stopper 27 is sandwiched between the discharge member 10 and the container main body 21. Thereby, the discharge member 10 is in a state sandwiched shallowly with respect to the container main body 21. In this state, the tip 23a of the inner plug 23 is in contact with the flange 19 formed on the inner surface of the discharge member 10. As a result, the flow path 15 of the discharge member 10 is divided by the tip portion 23a of the flange 19 and the inner stopper 23, so that the aseptic state of the contents liquid contained in the container main body 21 is maintained. It can be maintained at a higher level or the progress of deterioration (air oxidation, etc.) of the contents can be prevented.

4 and 5 show a series of steps of discharging operation by the first discharging member and the container having the same according to the present invention. 4A shows a state where no pressure is applied to the container body 21, and in this state, the valve body 13 of the discharge member closes the discharge hole 12. As shown in FIG. Therefore, the liquid content 24 contained in the container main body 21 does not discharge from the discharge part 11, but remains in the container main body 21 and the discharge member. FIG.4 (b) has shown the state which applied the pressure to the container main body 21. FIG. In this state, the hydraulic pressure is applied to the valve body 13 of the discharge member from the upstream side U by the liquid content 24, and the valve body 13 is compressed and deformed by this, so that the discharge hole 12 is closed. It is opened and the contents liquid 24 is discharged as the droplets 25.

FIG.5 (a) is the continuation of the state shown in FIG.4 (b), and has shown the state which stopped pressurization to the container main body 2l. In this state, since the hydraulic pressure by the contents liquid 24 is not applied to the valve body 13 of the discharge member, the valve body 13 is restored to the shape before pressurization, and the discharge hole 12 is closed again. In addition, FIG.5 (b) shows the state which the container main body 21 tries to restore to the shape before pressurization by stopping the pressurization to the container main body 21 in the continuation of the state shown in FIG.5 (a). . Since the valve element 13 of the discharge member closes the discharge hole 12 in this state, the inflow of outside air into the container main body 21 is realized only through the vent hole 16.

In another embodiment of the first discharge member 10 'and the container 20' having the same, shown in FIG. 6, the liquid filter 18 is provided on the flow path 15 connected to the discharge hole 12. FIG. It is installed. Therefore, as described above, even if a situation in which the residual liquid containing microorganisms, dust and the like flows back from the discharge hole 12 occurs, the container main body 21 in which the residual liquid is connected to the discharge member 10 '. Can be suppressed or prevented.

As for the 1st discharge member which concerns on this invention, the valve body 13a, 13b may have a cross-sectional shape as shown to FIG. 7 and FIG. 8, for example. That is, as in the discharge member 10a shown in FIG. 7, the tip part of the valve body 13a exposed by the discharge hole 12 may be flat, and like the discharge member 10b shown in FIG. 13b may be provided with the recessed part 13c in the front-end | tip. In particular, the valve body 13b of the shape shown in FIG. 8 is a valve body (the valve body shown in FIG. 1 or FIG. 7) which is not provided with the recessed part 13c, when a hydraulic pressure is received from the upstream U side. 13, 13a)), the compression deformation is more likely to occur (i.e., easy to open the discharge hole 12), and the problem that the discharge hole 12 is opened by the pressure from the outside of the discharge part 11 occurs well. It is not preferable in that it makes a discharge operation smooth and prevents a backflow.

[Second discharge member and container]

The 2nd discharge member 30 which concerns on this invention is a substantially cylindrical shape with a bottom provided with the discharge hole 32 in a bottom part as shown, for example in FIG. 9 (cross-sectional view) and FIG. 10 (exploded sectional drawing). Of the discharge portion 31 of the discharge portion 31, the ring-shaped valve body 33 disposed inside the discharge portion 31, and the opening end 31d side of the discharge portion 31, The valve seat portion 34 which abuts the upstream side U of the valve body 33 when the 32 is the downstream side D and the upstream side U from the valve body 33 through the ventilation filter 37. And a vent hole 36 connected to the oil passage 35.

The discharge part 31 needs to arrange the ventilation filter 37 in the ventilation hole 36, and is arrange | positioned at the discharge part main body 31a provided with the discharge hole 32, and the upstream side U of it. It consists of two members of the connection part 3 lb connected to the mouth part, such as a chemical liquid container. The discharge part main body 31a and the connection part 31b are integrated by the joining means, such as ultrasonic bonding, in the state which pinched | interposed the ventilation filter 17 in the flange 31f (connection part 31c).

Of the discharge member 30 shown in FIG. 9 and FIG. 10, the integrally molded article of the discharge part main body 31a and the valve body 33 is a ring-shaped valve body 33 as shown in FIG. 11. It adhere | attaches at least one part of the inner surface 31e of the discharge part main body 31a. 11 (a), the part shown with the dashed line with the reference numeral 36 has shown the ventilation hole covered by the ventilation filter 37. As shown in FIG.

Fig. 11B is a bottom view showing the integrally formed article of the discharge part main body 31a and the valve body 33. In the discharge part main body 31a shown in the figure, a hole penetrating the bottom part in the bottom part thereof is shown. (Injection hole: 31 g) is formed. Although the discharge part main body 31a can be shape | molded by injecting resin for forming the discharge part main body 31a in a metal mold | die, for example, after the injection, the opening end 31d side of the discharge part 31 (refer FIG. 10). ), The mold (movable mold) is replaced (or moved), and the thermoplastic elastomer is injected again from the injection hole 31g at the bottom of the discharge part main body 31a, whereby the discharge part main body 31a and the valve body 33 ) Can be produced by integral molding. In addition, in the case of integrally molding the valve body 33 from the opening end 31d side of the discharge portion, the injection hole 31g is not necessary.

In the discharge member 30 shown in FIG. 9 and FIG. 10, the valve seat portion 34 covered and mounted from the upstream side U in the discharge portion main body 31a has a plan view (a) and a bottom view (see FIG. 12). b), the cylinder 34c provided with the flange 34d, and the valve seat 34a arrange | positioned so that the mouth part on the opposite side to the flange 34d side of the said cylinder 34c may be provided may be provided. have. The part shown by 34b is a site | part which partitions the flow path 35, such as chemical liquid, simultaneously with the cavity part of the ring-shaped valve body 33. As shown in FIG. The part shown with 34e is the connection part of the cylinder 34c and the valve seat 34a.

In the integrally molded product shown in FIG. 11A, the valve body 33 is ring-shaped. However, the valve body is not limited to the one (continuous ring shape) continuous in the circumferential direction x of the discharge part main body 31a, and may be, for example, a shape as shown in Fig. 13A. Moreover, when the shape of a valve body is as shown to FIG. 13 (a), the flow path which arises between a valve seat (not shown) and the discharge part main body 31a 'according to the compression deformation of the valve body 33'. (Not shown) The area | region becomes narrow compared with the case where the valve body 33 is ring-shaped (FIG. 11). Therefore, what is necessary is just to set the shape of a valve body suitably according to the width | variety and narrowness of the flow path area | region calculated | required by the discharge member. In Fig. 13A, reference numeral 31e 'denotes an inner surface of the discharge unit main body 31a, and reference numeral 31f' denotes a flange of the discharge unit main body 31a.

FIG. 13B shows the valve seat 34 'used for the discharge member provided with the valve body 33' of the shape shown in FIG. What is necessary is just to form the flow path 35 of the valve seat part 34 'according to the shape of the valve body 33' of the discharge member shown to Fig.13 (a). In addition, in FIG.13 (b), the code | symbol 34a 'represents a valve seat.

For example, as shown in FIG. 14, the second discharge member 30 can be used by being attached to the mouth of the container main body 41.

15 and 16 show a series of steps of the discharge operation by the second discharge member and the container provided with the present invention. 15A shows a state where no pressure is applied to the container body 41. In this state, the valve body 33 is closed between the discharge part main body 31a side flow path 35 and the connection part 31b side flow path 35, and the discharge hole 32 and the container main body 41 are closed. Connection is blocked. Therefore, the liquid content 44 contained in the container main body 41 is not discharged from the discharge part 31 but stays in the container main body 41 and the discharge member 30. FIG.15 (b) has shown the state which applied the pressure to the container main body 4l. In this state, the valve body 33 receives the hydraulic pressure from the upstream side U via the flow path 35, and compression deformation is generated by the hydraulic pressure. Therefore, a space | gap arises between the valve body 33 and the valve seat 34a (the valve body 33 is open), and the flow path 35 of the discharge part main body 31a side flow path 35 and the connection part 31b side flow path 35 The connection is made through. As a result, the liquid content 44 contained in the container main body 41 is discharged from the discharge part 31 as the droplet 45.

FIG.16 (a) is the continuation of the state shown in FIG.15 (b), and has shown the state which stopped pressurization to the container main body 41. FIG. In this state, since the hydraulic pressure by the contents liquid 43 is not applied to the valve body 33 of the discharge member, the valve body 33 is restored to the shape before pressurization, and the valve body 33 and the valve seat ( Between 34a). FIG. 16 (b) shows the state which the container main body 41 tries to restore to the shape before pressurization by stopping the pressurization with respect to the container main body 41 in the continuation of the state shown in FIG. 16 (a). In this state, since the valve body 33 of the discharge member closes the flow path 35, the inflow of outside air into the container main body 41 is realized only through the vent hole 36.

As shown in FIG. 14 and FIG. 17, the inner stopper 43 is fitted to the neck portion 42 of the container 40. FIG. 14 shows a cross section in the use state of the container 40, while FIG. 17 shows a cross section in a state where the stopper of the container 40 is not opened. In the state which does not open the stopper shown in FIG. 17, the discharge member 30 is in the state fitted shallowly with respect to the container main body 41. FIG. In this state, the distal end portion 43a of the inner plug 43 is in contact with the flange 39 formed on the inner surface of the discharge portion 3l. As a result, the flow path 34 of the discharge member 30 is divided by the flange portion 39 and the distal end portion 43a of the inner stopper 43, so that the aseptic state of the contents liquid contained in the container body 21 can be seen. It can be maintained at a high level or can prevent the progress of deterioration (air oxidation, etc.) of the contents solution.

In the discharge member 30 shown in FIG. 17, a cap 46 is screwed on the threaded portion 31h of the discharge portion main body 31a, and on the inner surface of the cap 46, a discharge member ( The sponge 47 is disposed at the portion in contact with the discharge hole 32 of the 31. Since the sponge 47 absorbs the residual liquid 35 '(refer to FIG. 16 (b)) remaining in the discharge hole 32 after completion of the discharge operation, the sponge 47 does not discharge the residual liquid again during the dropping operation. You can do that. In addition, the code | symbol 46a represents the thread part formed in the inner surface of the cap 46. As shown in FIG.

In the discharge member 30 shown in FIG. 17, the opening end 46b of the cap is blocking the vent hole 36 of the discharge member 30. As a result, it is possible to prevent the solvent (water) and the like of the chemical liquid contained in the container main body 41 from gradually evaporating and oxidizing from the ventilation filter 37 to cause a problem such as a change in the pH of the aqueous solution.

The second discharge member is not limited to the above, but may be, for example, in the shape shown in FIG. 18.

The discharge member 30 'shown in FIG. 18 has a bottomed substantially cylindrical discharge part 31 having a discharge hole 32 at the bottom, as in the case of the discharge member 30 shown in FIG. The ring-shaped valve body 33 ′ disposed inside the discharge part 31 and the opening end side of the discharge part 3 l are covered with each other, and the discharge hole 32 is directed to the downstream side D. FIG. The valve seat portion 34 abuts on the upstream side U of the valve body 33 ', and a vent hole 36 connected to the flow path 35 via the vent filter 37. The liquid supply filter 38 arrange | positioned at the upstream side U rather than the valve seat part 34 and covers the flow path 35 is provided. This discharge member 30 is provided with a fluid filter 38 in the flow path 35 from the one having a different shape of the valve body 31 and a shape in the vicinity of the discharge hole 32 of the discharge portion 31 containing the same. It is the same as the discharge member 10 shown in FIG.

[Third Discharge Member and Container]

The 3rd discharge member 50 which concerns on this invention is a substantially cylindrical shape with a bottom provided with the discharge hole 52 in a bottom part, for example as shown to FIG. 19 (cross-sectional view) and FIG. 20 (exploded sectional drawing). In the discharge part 51 of the discharge part 51 and the flow path 55 connected to the discharge hole 52 in the discharge part 51, and the discharge hole 52 in the state in which the hydraulic pressure is not received from the upstream side U. FIG. And the valve body 53 of the elastic body which deforms and opens the discharge hole 52 when the hydraulic pressure is received from the upstream side U, and the upstream side U from the valve body 53 through the vent filter 57. Vent holes 56 connected to the flow path 55 of the circumferential path 55.

The discharge part 51 needs to arrange the ventilation filter 57 in the ventilation hole 56, and it is arrange | positioned in the discharge part main body 51a provided with the discharge hole 52, and the upstream side U. It consists of two members of the connection part 5 lb connected to the mouth part, such as a chemical liquid container. The discharge part main body 51a and the connection part 51b are integrated by the joining means, such as ultrasonic bonding, in the state which pinched | circulated the ventilation filter 57 between the flange 51f (connection part 51c).

FIG. 21: is a top view (drawing seen from the upstream side U) of the discharge part main body 51a. As shown in this figure, the projection part (valve seat 52b) for screwing-engagement with the protrusion of the valve main-body part 53a is formed in the bottom part of the substantially cylindrical discharge part main body 51a. In addition, vent holes 56 are formed at predetermined intervals in the flange 51f (connection portion 51c) portion for mounting the connecting portion 51b paired with the discharge part main body 51a. 56, a ventilation filter 57 for realizing the inflow of sterile air is arranged.

FIG. 22: shows the combined body of the valve body 53 and the valve body support member 54 which connects and fixes this, FIG. 22: A is the top view (FIG. Seen from the upstream side U), FIG. (b) is the bottom view (drawing seen from the downstream side D). As shown in this figure, the valve body supporting member 54 for arranging the valve body 53 in the discharge part main body 51a is a screw with the cylinder body 54a and the valve body 53 in the bottom part. A connection fixing portion 54b for realizing a mechanical coupling and a flange portion 54c at an opening end opposite to this and fitted with the discharge portion main body 51a are provided.

19-22, after the valve body 53 is fixedly connected to the valve body support member 54, it is fitted in the inner surface 51e of the discharge part main body 51a.

In the case where the valve body 53 is formed using an elastomer material having thermoplasticity (such as a thermoplastic elastomer), the valve body 53 and the valve body supporting member 54 may be integrally formed by insert molding or multicolor molding. Can be. Thereby, both members can be manufactured simply. When the molding material such as injection molding cannot be used because the elastic material forming the valve body 53 does not have thermoplasticity, the valve body supporting member 54 is inserted into a mold for molding, for example. Thereafter, by molding the valve body 53, the valve body and the valve body support member 54 can be integrally formed.

In the embodiment shown in FIG. 19, the valve body 53 is a valve body 53a serving as a valve shaft, a protrusion 53b at the tip of the valve body 53a, and a valve body 53 forming a valve head, and a valve body. And a flange portion 53c for screwing the portion 53a to the valve body support member.

For example, as shown in FIG. 23, the elastic member shown in FIG.19 and FIG.20 is a valve body provided with the valve body 53 in the opening end (refer reference numeral 51d of FIG. 20) of the discharge part main body 51a. The support member 54 is inserted, and the projection 53b of the valve body portion 53a is disposed on the protrusion 52b formed in the flow path inner wall 52a of the discharge portion 52, and then the strong portion is supported from the upstream side U. It is obtained by loading a hydraulic pressure or air pressure and sliding the projection 53b of the valve body toward the discharge hole 52 side.

As shown in FIG. 24, the said 1st discharge member 50 can be used by attaching to the entrance part of the container main body 61, for example. Moreover, in the container 60 shown in FIG. 24, the internal stopper 63 is formed in the neck part 62 of the container main body 61. As shown in FIG.

25 and 26 show a series of steps of the discharge operation using the discharge member of the present invention and a container provided with the same. 25A shows a state where no pressure is applied to the container body 61. In this state, between the flow path 55 in the discharge hole 52 and the flow path 55 located upstream from the valve body 53 is closed by the valve body 53, and the discharge hole 52 and the container are closed. The main body 61 is connected and blocked. Therefore, the contents liquid 64 contained in the container main body 61 is not discharged from the discharge portion 51 but stays in the container main body 61 and the discharge member 50. 25B shows a state where a pressure is applied to the container body 61. In this state, the valve body 53 receives the hydraulic pressure from the upstream side U via the flow path 55, and the deformation is generated in the discharge hole 52 side by the hydraulic pressure. Therefore, between the protrusion 53b of the valve body portion 53a and the fin tank 52b formed in the flow path inner wall 52a of the discharge portion 52, the fluid flows into the container main body 61. ) Is discharged from the discharge portion 51 as the droplet 65.

FIG.26 (a) is the continuation of the state shown in FIG.25 (b), and has shown the state which stopped pressurization to the container main body 61. FIG. In this state, since the hydraulic pressure by the contents liquid 64 is not applied to the valve body 53 of the discharge member, it is restored to the shape before pressurization, and the valve body 53 and the protrusion 52b are closed again. FIG.26 (b) is the continuation of the state shown in FIG.26 (a), and has shown the state which the container main body 61 is going to restore to the shape before pressurization. In this state, since the valve body 53 of the discharge member closes the flow path 55 in the protruding portion 52b of the discharge portion, the inflow of outside air into the container main body 61 is provided only through the vent hole 56. Is realized.

As shown in FIG. 24 and FIG. 27, the inner cap 63 is fitted to the neck portion 62 of the container 60. The operation of the inner stopper 63 is the same as in the case of the container 40 provided with the second discharge member 30. In addition, although FIG. 24 shows the cross section in the use state of the container 60, FIG. 27 has shown sectional drawing in the state which did not open the stopper of the container 60. As shown in FIG. In FIG. 27, the code | symbol 63a shows the front-end | tip of the internal stopper 63, and the code | symbol 59 shows the flange formed in the inner surface of the discharge part 51. As shown in FIG.

In the discharge member 51 shown in FIG. 27, a cap 66 is formed on the threaded portion 51h of the discharge portion main body 51a in a threaded manner, and the discharge member 51 is formed on the inner surface of the cap 66. The sponge 67 is arrange | positioned in the site | part which contacts the discharge hole 52 of 51. As shown in FIG. In addition, the opening end 66b of the cap is blocking the ventilation hole 56. The action of the sponge 67 and the opening end 66b of the cap is the same as in the case of the container 40 provided with the second discharge member 30. In addition, in FIG. 27, the code | symbol 66a shows the screw part formed in the inner surface of the cap 66. As shown in FIG.

[Fourth discharge member and container]

As for example, as shown in FIG. 28, the 4th discharge member 70 which concerns on this invention has a bottomed substantially cylindrical discharge part 71 with a discharge hole 72 in a bottom part, and a discharge part. On the outer surface side of 71, it contacts the valve seat 74, closes the discharge hole 72 in the state which is not receiving the hydraulic pressure from the upstream side U, and receives a hydraulic pressure from the upstream side U, and it deform | transforms a deformation | transformation. And a vent hole 76 connected to an upstream side of the valve body 73 through the vent filter 77 and a valve body 73 to open the discharge hole 72.

The discharge part 71 needs to arrange the ventilation filter 77 in the ventilation hole 76, and the discharge part main body 71a provided with the discharge hole 72 similarly to the case of the said 1st discharge member. And a connecting member 71b disposed on the upstream side U thereof and connected to a mouth of a chemical liquid container or the like. The discharge part main body 71a and the connection part 17b are integrated by the joining means, such as ultrasonic bonding, in the state which pinched | circulated the ventilation filter 77 between the flange 71f (connection part 71c).

FIG. 29A is a bottom view (view seen from the downstream side D) of the discharge part main body 71a, and FIG. 29B is a sectional view taken along the line A-A in FIG. In the discharge part main body 71a, in the flange 71f (connection part 71c) part for attaching the connection part 71b paired with this, the some ventilation hole 76 similar to the case shown in FIG. And a ventilation filter 77 that closes the ventilation hole. The operation of the vent hole 76 and the vent filter 77 is the same as in the case of the container 60 provided with the third discharge member 50.

As shown in FIGS. 28-29, the valve body 73 has the bottom outer surface of the discharge part main body 71a which is a bottomed substantially cylindrical member, and the bottom part of the said discharge part main body 71a. And the bottom face (outer surface) in the valve seat 74 for closing the flow path 75 and closing the discharge part, and is disposed in contact with both sides. It is preferable that the valve body 73 is integrally molded with the discharge part main body 71a on the outer surface side of the resin discharge part main body 71a, for example, using a thermoplastic elastomer having thermoplasticity. Do. By integral molding, the discharge member 70 can be manufactured easily.

For example, as shown in FIG. 30A, the fourth discharge member 70 can be used by attaching to the mouth of the container main body 81. Moreover, in the container 80 shown to FIG. 30 (a), the internal stopper 83 is formed in the neck part 82 of the container main body 81. As shown in FIG. The operation of the inner stopper 83 is the same as in the case of the container 40 provided with the second discharge member 30 or the container 60 provided with the third discharge member 50.

30 and 31 show a series of steps of a discharge operation using the discharge member of the present invention and a container provided with the same. 30A shows a state where no pressure is applied to the container body 81. In this state, the flow path 75 in the discharge hole 72 is closed by the valve body 73, so that the outside of the discharge hole 72 and the container main body 81 are connected to each other and are blocked. Therefore, the contents liquid 84 contained in the container main body 81 is not discharged from the discharge portion 71 but stays in the container main body 81 and the discharge member 70. 30 (b) shows a state in which pressure is applied to the container body 81. In this state, the valve body 73 receives the hydraulic pressure from the upstream side U via the flow path 75, and the deformation is generated in the discharge hole 72 side by the hydraulic pressure. Therefore, a flow path is formed between the valve body 73 and the valve seat portion 74, and the liquid content 84 contained in the container main body 81 is discharged from the discharge portion 71 as the droplet 85.

FIG.31 (a) has shown the state which stopped pressurization to the container main body 81 by the continuation of the state shown in FIG.30 (b). In this state, since the hydraulic pressure by the contents liquid 84 is not applied to the valve body 73 of the discharge member, it is restored to the shape before pressurization and the valve body 73 and the valve seat 74 are closed again. . FIG. 31 (b) is a continuation of the state shown in FIG. 31 (a), and has shown the state which the container main body 81 tries to restore to the shape before pressurization. In this state, since the valve body 73 of the discharge member closes the flow path 75 between the valve seat 74 of the discharge part 71a, the inflow of outside air into the container main body 81 is only a vent hole. Through 76.

The discharge member 70 'shown in FIG. 32 is another embodiment of the fourth discharge member. When the thermoplastic material having thermoplasticity is used as the material of the valve body, the valve body 73 and the discharge part main body 71a can be integrally formed as in the discharge member 70 shown in FIG. On the other hand, the valve body 73 may be made of an elastic body other than the thermoplastic elastomer, that is, rubber having no thermoplasticity or the like, as long as the valve body 73 is sufficiently flexible and can be easily bent and deformed by hydraulic pressure. When the elastic material forming the valve body does not have thermoplasticity and cannot be molded by injection molding or the like, for example, as shown in the embodiment shown in FIG. 32, the valve body 73 ′ is discharged. What is necessary is just to arrange | position in the discharge part 71 by clamping between 71a ') and the valve seat 74 (and the cylinder 74a).

The discharge member 70 'shown in FIG. 32 is the same as the discharge member 70 shown in FIG. 28 except that the discharge part main body 71a' and the valve body 73 'differ.

[Fifth Discharge Member and Container]

For example, as shown in FIG. 33, the fifth discharge member 90 according to the present invention includes a substantially cylindrical discharge portion 91 having a bottom having a hole 91d in its bottom portion, and an approximately annular shape. Valve body portion 93b and a substantially annular thin portion 93a formed successively therewith, the valve body portion in a state in which the thin portion 93a is exposed from the hole 91d to the discharge portion 91 outside. A valve body 93 formed by fixing the 93b to the inside of the discharge part 91 and a columnar shape arranged inside the discharge part 91 and partitioning the discharge hole 92 simultaneously with the valve body 93. Valve body support portion 94a and a vent hole 96 connected to the flow path 95 on the upstream side U of the valve body 93 via the air filter filter 97.

Although the discharge hole 92 is normally closed by the thin part 93a of the valve body 93, when the hydraulic pressure is applied to the valve body 93 from the upstream side through the flow path 95, the thin part 93a The deformation | transformation deformation generate | occur | produces in this space, and the space | gap arises between the thin part 93a and the valve body support part 94a. Thereby, the liquid content can be discharged through the gap.

In the embodiment shown in FIG. 33, the valve body 93 is a discharge part main body in a state in which the thin part 93a is exposed to the hole 91d of the discharge part 91 (the discharge part main body 91a). It is fixed to the inner surface of 91a. In FIG. 33, the code | symbol 94c hold | maintains the valve body support part 94a and the flange part 94b, and the cylinder part which fixes the valve body support member 94 in the discharge part 91 (ejection part main body 91a) Indicates. The valve main body 93b should just have a thickness sufficient to integrate with the inner surface of the discharge part main body 91a.

The discharge part 91 needs to arrange the ventilation filter 97 in the ventilation hole 96, and it is arrange | positioned in the discharge part main body 91a provided with the discharge hole 92, and the upstream side U. It consists of two members of the connection part 91b connected to entrance parts, such as a chemical liquid container. The discharge part main body 91a and the connection part 91b are integrated by the joining means, such as ultrasonic bonding, in the state which pinched | circulated the ventilation filter 97 in the connection part 91c.

For example, as shown in FIG. 34, the fifth discharge member 90 can be used by attaching to the mouth of the container main body 101.

36 and 37 show a series of steps of the discharge operation by the fifth discharge member 90 and the container 100 having the same according to the present invention. 36 (a) shows a state where no pressure is applied to the container body 101, and in this state, the valve body 93 of the discharge member closes the discharge hole 92. Therefore, the contents liquid 104 contained in the container main body 101 does not discharge from the discharge portion 91 but stays in the container main body 101 and the discharge member. 36 (b) shows a state in which pressure is applied to the container main body 101. In this state, the hydraulic pressure by the contents liquid 104 is applied to the valve body 93 of the discharge member from the upstream side U. As a result, the valve body 95 extends and deforms, so that the discharge hole 92 is closed. It is opened and the contents liquid 104 is discharged as the droplets 105. In addition, FIG. 38 expands and shows the state of the discharge part 91 shown to FIG. 36 (b),

FIG. 37A shows the state in which the pressurization to the container main body 101 is stopped in the continuation of the state shown in FIG. 36B. In this state, since the hydraulic pressure by the contents liquid 104 is not applied to the valve body 93 of the discharge member, the valve body 93 is restored to the shape before pressurization, and the discharge hole 92 is closed again. In addition, FIG. 37 (b) shows the state which the container main body 101 tries to restore to the shape before pressurization by stopping the pressurization with respect to the container main body 101 in the continuation of the state shown in FIG. 37 (a). . Since the valve element 93 of the discharge member closes the discharge hole 92 in this state, the inflow of outside air into the container main body 101 is realized only through the vent hole 96.

In the container 100 shown in FIG. 34, the discharge member 90 is attached to the neck portion 102 of the container 100 via an internal stop 103. The inner stopper 103 slides freely into the neck portion 102 of the container 100, and FIG. 34 illustrates a cross section in the use state of the container 100. 3, 17, 27, and the like, in terms of the state where the distal end portion 103a of the internal stop 103 and the flange 99 are engaged (that is, the state where the stopper is not opened) and the effect of the engagement of both. It is the same as the case in the other embodiment shown.

In the discharge member 90 shown in FIG. 35, a cap 106 is formed on the outer surface of the discharge part main body 91a by a screw type. The cap 106 has a recessed portion 108 formed at a position facing the discharge hole 92 in a state where the cap 106 is screwed with the discharge portion main body 91a, and the cap 106 has a cap in the recessed portion 108. The inner surface of the 106 and the discharge hole 92 are in contact with each other. A sponge 107 is formed around the recess 108, and the residual liquid 105 ′ (see FIG. 37 (b)) remaining in the discharge hole 92 is a cap at the recess 108. It is pushed out by the inner surface and absorbed by the sponge 107.

In the discharge member 90 shown in FIG. 35A, the opening end 106a of the cap blocks the vent hole 96 of the discharge member 90. As a result, the solvent (water) etc. of the chemical liquid accommodated in the container main body 101 can be evaporated and oxidized gradually from the ventilation filter 97, and the problem that the pH of aqueous solution changes, etc. can be prevented.

In another embodiment of the fifth discharge member 90 'shown in FIG. 39, not only the contact between the thin film portion 93a and the valve body support portion 94a, but also the valve body portion 93b of the valve body 93 ′. Closing of the flow path 95 is also realized when ') abuts against the flange portion 94b of the valve body support member 94. Therefore, it is possible to stably exert the effect of closing the flow path 95 by the valve body 93 ', and furthermore, a situation in which residual liquid containing microorganisms, dust, and the like flows back from the discharge hole 92 occurs. It can be highly prevented. 40 enlarges and shows the state of the discharge part 91 in the discharge member 90 'shown in FIG.

In the fifth discharge member 90, 90 ', the opening and closing position of the flow path 95 (abutment position of the thin film portion 93a and the valve body support portion 94a, the valve body portion 93b' and the flange portion 94b) ), A fluid filter (not shown) may be formed on the upstream side. The effect by having a liquid filter is the same as that in the other embodiment shown to FIG. 6, FIG.

In the container 100 provided with the fifth discharge member, when the container is used for the purpose of discharging droplets of about 20 to 40 µL in one discharge operation as in the case of the eye drop container, the valve body support portion ( The outer diameter of 94a) is set in the range of 0.6-2.0 mm, Preferably it is 1.0-1.2 mm. Moreover, the thickness in the thin film part 93a of the valve body 93 is set to 0.8-2.5 mm, Preferably it is set in the range of 0.8-1.5 mm.

It is preferable that the thin film part 93a of the valve body is slightly pressed and expanded by the valve body support part 94a from the viewpoint of preventing the liquid leakage from the discharge hole 92. Therefore, it is preferable to set so that the inner diameter of the thin film part 93a in the state which does not let the valve body support part 94a pass through is smaller than the outer diameter of the valve body support part 94a. Specifically, the inner diameter of the thin film portion 93a may be set to be 50 to 99%, preferably 50 to 90%, and more preferably 60 to 80% with respect to the outer diameter of the valve body support portion 94a. In addition, as shown in FIG. 39, not only the contact between the thin film portion 93a of the valve body 93 and the valve body support portion 94a of the valve body support member 94, but also the valve body of the valve body 93 ′. In the discharge member 90 'which achieves the closing of the flow path 95 by abutting the portion 93b' and the flange portion 94b of the valve body support member 94, the liquid in the discharge hole 92 Since the effect of preventing leakage is high, the inner diameter of the thin film portion 93a can be designed with more margin than in the case described above.

Next, each part of the discharge member of this invention and the container provided with it is demonstrated in detail.

(Valve body)

The valve element in the discharge member of the present invention is easily compressed or deformed by the hydraulic pressure from the container main body side and the hydraulic pressure lower than the hydraulic pressure of the ventilation filter, and also by the ventilation pressure from the outside of the ventilation filter. It does not need to be compressed or stretched. Specifically, as a material which can be used as a valve body, it is a thermoplastic elastomer of low hardness; Gel-like material; Rubbers such as natural rubber, silicone rubber, isoprene rubber, butyl rubber, butadiene rubber and fluorine rubber.

Although it does not specifically limit about the more specific kind of these materials, In order to implement | achieve the said characteristic about the elongation or compression deformation, the hardness of a valve body is also described in JIS A hardness [JIS K 6301-5.2 "spring hardness test". It is required to be in the range of 0-40 in the spring hardness Hs (type A) measured by the method. It is preferable that especially the hardness (JIS A) of a valve body is JISA30 or less in the said range, More preferably, it is 20 or less, More preferably, it is 10 or less. On the other hand, the lower limit of the hardness (JIS A) of the valve body is not limited to the above range, but may be two or more in JIS A in view of the availability of materials, the strength of the valve body, and the like.

The specific example of the said valve body forming material is as follows. As the thermoplastic elastomer, for example, styrene-ethylene / butylene-styrene block copolymer (SEBS), styrene-butadiene-styrene block copolymer (SBS), styrene-isoprene-styrene block copolymer (SIS), maleic acid modified Styrene-based elastomers such as modified SEBS, styrene-ethylene / propylene-styrene block copolymer (SEPS), styrene-ethylene / butylene block copolymer (SEB), and styrene-ethylene / propylene block copolymer (SEP); Olefin elastomers such as ethylene-propylene block copolymers; Polyurethane-based elastomers; And mixtures thereof. Among the styrene-based thermoplastic elastomers, "Sefton (R) compound" manufactured by Kuraray Plastics Co., Ltd. is preferable.

As a gel-like substance, For example, the gel which consists of a linear hydrocarbon type polymer (olefin type elastomer) ["Cosmo gel" by Cosmo Group Co., Ltd. product); Silicone urethane gel [The brand name "Chemek gel" by Chemtech Co., Ltd.] etc. are mentioned.

The elastic body which forms a valve body may be a foam (however, a hole is discontinuous and it did not let a liquid pass), and the hardness may be set to the said range by the additive.

As an index indicating the degree of deformation due to the hydraulic pressure of the valve body, in addition to the above hardness, for example, tensile stress, compressive modulus of elasticity, etc. of the elastic body can be mentioned. The elastic body used for the valve body is 50 or less in its compressive permanent strain (CS) (JIS K 7301, measuring conditions: 70 ° C x 22 hours) so as not to be damaged even if the hydraulic pressure is repeatedly loaded and removed. It is preferable. In the case where the discharge member is the discharge portion of the eye drop container, considering that the dropping speed of the eye drop in the general eye drop operation is about 0.05 mL / sec, the pressure required to compress or elongate the valve body is 0.01 to 0.2 MPa. It is preferable that it is about degree.

In the case where the valve bodies 33 and 33 'are fixed to the inner surface 31e of the discharge portion 31 as in the discharge members 30 and 30' shown in Figs. What is necessary is just to select the material which has a structure, and integrally shape | mold the valve body 33, 33 'and the discharge part main body 31a.

As in the discharge member 70 shown in FIG. 28, in the case of mounting to the discharge hole 72 portion of the discharge part main body 71a, a material having thermoplasticity is selected from the above-described elastic material, and the valve body 73 is selected. And the discharge part main body 71a may be molded integrally.

On the other hand, like the discharge member 70 'shown in FIG. 32, the valve body is sandwiched between the discharge part main body 71a' and the cylinder 74a formed in series with the valve seat 74, and the discharge part 70 is carried out. In the case of arranging at "), the elastic material for forming the valve body is not limited to a material having thermoplasticity.

(Vent filter)

As described above, the ventilation filter used in the present invention is such that the fluid pressure exceeds the pressure at which the valve body deformation of the discharge member causes two modes of compression and expansion, and the ventilation pressure outside thereof is It should be less than the pressure to open the discharge hole.

Since the hydraulic pressure required for discharging the liquid contents by generating two methods of compression and elongation of the valve body deformation of the discharge member varies depending on the speed of the discharge operation (dripping speed of the discharged droplets). In addition, it is necessary to set the liquid pressure and the air pressure required for the air filter according to the use of the discharge member, the speed of the discharge operation generally assumed, and the like.

Specifically, in the case where the discharge member is the discharge portion of the eye drop container, the dropping speed of the eye drop in the general eye drop operation is about 0.05 mL / sec, in which case the aspect of the valve body deformation causes compression or / and elongation of the eye drop Since the pressure necessary for dropping the amount is about 0.01 MPa to 0.2 MPa, if the fluid pressure of the air filter exceeds at least 0.01 MPa, preferably 0.2 MPa, the eye drop can be prevented from leaking from the air vent during eye drop operation. Can be.

In addition, after the eye drop is dropped in a general eye drop operation, the rate (intake rate) of introducing air into the eye drop container is about 1 to 10 mL / sec. Here, if the ventilation pressure of the ventilation filter is less than at least 0.005 MPa, preferably less than 0.001 MPa, it is possible to smoothly introduce outside air from the ventilation holes.

The pore diameter of the ventilation filter is air only without passing through the liquid discharged by the discharge member of the present invention (content liquid such as chemical liquid contained in the container of the present invention), microorganisms such as bacteria, dust and foreign matter in the air, and the like. It is set in the range which can be made to pass, and is usually set to about 0.1 to 0.45 mu m, preferably about 0.1 mu m.

Although the ventilation filter which can be used for this invention is not limited to this, For example, the hydrophobic polytetrafluoroethylene (PTFE) membrane of the Japan company Ago, Sure Vent Durapoa (R) of Nippon Mirpoa, Inc. [polyfluorination Vinylidene (PVDF) product] etc. are mentioned.

(Passage filter)

The liquid filter used for this invention is a filter which permeate | transmits a liquid by adding a fixed liquid pressure or more. In the case where such a fluid filter is formed upstream of the discharge hole, as described above, even if a situation in which the residual liquid in the discharge hole flows back occurs, the residual liquid penetrates into the container body connected to the discharge member. This can be prevented by the filter.

Although the fluid filter which can be used for this invention is not limited to this, For example, the hydrophilic PTFE membrane of the Japan company, the hydrophilic Durapoa (R) (made by PVDF) of Nippon Milipoa, the hydrophilic polyether sulfone of the same company (PES) membrane etc. are mentioned.

[cap]

In the discharge member of the present invention, an antibacterial treatment may be applied to the cap which covers the outer surface of the discharge portion in addition to or instead of the antibacterial treatment for the discharge hole. Although the site | part of the cap used as an object of antibacterial treatment is not limited to this, The site | part which contact | connects a discharge hole among the inner surfaces, or the sponge arrange | positioned inside the cap are mentioned.

Since the discharge member of the present invention does not cause backflow from the discharge hole side to the upstream side, the residual liquid after the discharge operation is not flowed into the discharge portion and remains around the discharge hole. Thus, for example, by using a cap having an absorbent material therein, the absorbent liquid (residual liquid) remaining in the vicinity of the discharge hole after the discharge operation is absorbed by the absorbent material, so that the residual liquid is discharged again during the dropping operation. May be avoided (see FIGS. 17 and 27).

In the case where the sponge is antimicrobial treated and brought into direct contact with the discharge hole, there is a fear that the antibacterial agent will leak out of the sponge and adhere to the discharge hole over time. Thus, the remaining liquid of the discharge hole pushed by the inner surface of the cap may be absorbed by the absorber formed around the inner surface of the cap without directly contacting the sponge and the discharge hole (see Fig. 35).

As a specific example of an absorber, For example, Sponge which consists of urethane, foamed polyethylene, etc .; Woven fabrics composed of nonwoven fabrics, cotton wool, gauze and the like; Paper, hydrogel, etc. are mentioned. What is necessary is just to use various conventionally well-known materials, such as urethane and foamed polyethylene, for formation of a sponge. In order to carry out antibacterial treatment to a sponge, for example, it is preferable that the agent is attached to the surface of the sponge by means of coating or the like after the preparation of the sponge, or the agent such as an antibacterial agent is previously kneaded in urethane or polyethylene. Moreover, you may use the thing which has antimicrobial previously in the raw material itself of an absorber.

As an antibacterial treatment with respect to the said cloth, paper, hydrogel, etc., the method of giving these processes, such as a silane coupling and selenium coating, is mentioned, for example. As a specific example of a hydrogel, what consists of combining polymers, such as a (meth) acrylamide type, and water swellable clay minerals, for example (Unexamined-Japanese-Patent No. 2002-53629, Unexamined-Japanese-Patent No. 2000-53762) Can be mentioned.

(Materials for discharging member, cap and container body)

As resin which forms a discharge member, a cap, and a container main body, polyethylene (PE), polypropylene (PP), etc. are mentioned, for example. In particular, since PE or PP is a medicinally safe material, it is particularly preferable when the container of the present invention contains a chemical liquid such as an eye drop container.

The resin forming the discharge member, the cap and the container body is further improved from the viewpoint of enhancing the effect of preventing the liquid remaining in the vicinity of the discharge hole or the like and the corruption of the liquid contained in the container body after discharge operation. You may knead the preservative etc. beforehand. As a specific example of a preservative, the quaternary ammonium salt (For example, brand name "Dimer 38 (R)" by Inui Co., Ltd., "Dimer 136 (R)" by the same company), etc. are mentioned.

In addition, after the discharge member, the cap and the container body are formed, an antiseptic may be attached to the inner surface of the discharge member, the cap and the container body by means of coating or the like, or the surface treatment may be performed by silane coupling or the like when the discharge member, the cap and the container body are formed. do. You may use what has antimicrobial activity to the raw material itself of resin which forms a discharge part.

According to the discharge member of the present invention, it is possible to smoothly restore the container after the discharge processing and the discharge operation, while highly preventing the reverse flow of the liquid discharged from the discharge hole and the subsequent invasion of microorganisms and dust.

In the discharge member of the present invention, the deformation of the valve body is achieved by a liquid pressure lower than the liquid pressure of the vent filter, so that the discharge can be reliably discharged from the discharge hole without causing liquid leakage in the vent hole during the discharge operation. Can be. In addition, since opening of the flow path connected to the discharge hole and / or the discharge hole is not achieved by the ventilation pressure from the outside to the ventilation filter, external air flows from the discharge hole instead of the ventilation hole when the container body is restored. There is no problem or a problem such as leakage of the contents liquid from the discharge hole. Therefore, according to the discharge member of the present invention, it is possible to smoothly restore the container after the discharge process and the discharge operation, while highly preventing the reverse flow of the liquid discharged from the discharge hole and the subsequent invasion of microorganisms and dusts. have.

Moreover, since the discharge member of this invention does not arrange | position a porous filter in a discharge part like the antimicrobial container of Unexamined-Japanese-Patent No. 2001-179017 and 2001-206454 mentioned above, for example, Even when the liquid is a suspension, there is a very low risk of clogging in the discharge hole. Although it depends on the size, material, etc. of a valve body and a discharge hole, clogging does not occur in a discharge hole normally when the particle diameter of suspended particle is about 50 micrometers.

Since the container of the present invention includes the discharge member of the present invention at its inlet, the once discharged contents liquid flows back to the container body, and microorganisms such as bacteria, dust, foreign matters, etc. enter the container body accordingly. Also, it can be highly prevented, and therefore, it is not necessary to formulate a medicament (for example, a preservative) for preventing the decay or deterioration of the contents, or make the formulation as small as possible. In addition, since the container of the present invention does not use a porous filter in the discharge portion, clogging in the discharge hole does not occur, so that, for example, even if the liquid is a suspension, the liquid is smoothly provided except for a liquid filter upstream of the discharge hole. Discharge can be realized.

The container of the present invention further includes an inner stopper which slides freely in the flow path of the discharge member or in the container body, wherein the inner stopper contacts the inner wall of the flow path of the discharge member when the container is not in use to close the flow path. It is preferable. In this case, it is possible to ensure the aseptic state of the contents liquid until the use of the container is confidential, and furthermore, it is possible to prevent the contents liquid from contacting the valve body or the ventilation filter in the unused state, so that the quality is stable for a long time. You can. The container of the present invention is preferable as an eye drop container containing, for example, an eye drop.

Claims (19)

A substantially cylindrical or substantially main-shaped discharge part having a bottom having discharge holes at the bottom thereof; When the discharge hole side is made downstream, the flow path within the discharge hole connected to the discharge hole and / or the discharge hole in a state in which the hydraulic pressure is not received from the upstream side is closed, and is deformed when the hydraulic pressure is received from the upstream side. A valve body made of an elastic body which opens the discharge hole and / or the flow path, A ventilation hole connected to a flow path upstream from the valve body via a ventilation filter, The deformation of the valve body is achieved by a liquid pressure smaller than the liquid pressure of the vent filter, and the opening of the discharge hole and / or the flow path is not achieved by the vent pressure from the outside to the vent filter. Discharge member. A substantially cylindrical or substantially main-shaped discharge part having a bottom having discharge holes at the bottom thereof; Disposed in the discharge portion, the discharge hole is closed when the discharge hole side is downstream, and the discharge hole is closed without receiving hydraulic pressure from the upstream side; A valve body made of an elastic body, A connection fixing part disposed inside the discharge part to partition a flow path between the discharge part inner surface and to fix the valve body on an upstream side thereof; A vent hole connected to a flow path upstream from the valve body via a vent filter, Compression deformation of the valve body is achieved by a liquid pressure smaller than the fluid pressure of the vent filter, and opening of the discharge hole and / or the flow path is not achieved by the vent pressure from the outside to the vent filter. Phosphorus discharge member. The discharge member according to claim 2, wherein the valve body and the connection fixing part are integrally molded. A substantially cylindrical or substantially main-shaped discharge part having a bottom having discharge holes at the bottom thereof; A valve seat fixed in the discharge portion, When the discharge hole is fixed to the inner surface of the discharge part and the discharge hole is in the downstream side, the flow path contacting the valve seat on the downstream side and connected to the discharge hole in a state without receiving the hydraulic pressure is closed, and the hydraulic pressure is increased from the upstream side. A substantially cylindrical valve body made of an elastic body that is compressed and deformed to open the flow path between the valve seat and Vent hole connected to the flow path upstream from the said valve body through a vent filter And Compression deformation of the valve body is achieved by a liquid pressure smaller than the fluid pressure of the vent filter, and opening of the discharge hole and / or the flow path is not achieved by the vent pressure from the outside to the vent filter. Phosphorus discharge member. The discharge member according to claim 4, wherein the valve body and the discharge unit are integrally molded. A substantially cylindrical or substantially main-shaped discharge part having a bottom having discharge holes at the bottom thereof; It is disposed in the discharge portion, and when the discharge hole side is made downstream, the deformation is extended when the discharge hole or the flow path connected to the discharge hole is closed without receiving hydraulic pressure from the upstream side, and the hydraulic pressure is received from the upstream side. A valve body made of an elastic body to open the discharge hole or the flow path, Vent hole connected to the flow path upstream from the said valve body through a vent filter And Discharge deformation of the valve body is achieved by a liquid pressure smaller than the liquid pressure of the vent filter, and opening of the discharge hole or the flow path is not achieved by the vent pressure from the outside to the vent filter. absence. The valve body according to claim 6, wherein the valve body has a valve body portion fixed in the flow path, and a projection at the distal end of the discharge hole. The projection at the tip of the valve body portion is engaged with the protrusion formed on the inner wall of the flow path connected to the discharge hole on the downstream side to close the flow path. And the valve body portion extends and deforms downward when the hydraulic pressure is received from the upstream side, thereby forming a gap between the projection at the tip of the valve body portion and the protrusion on the inner wall of the flow path. A substantially cylindrical or substantially main-shaped discharge part having a bottom having discharge holes at the bottom thereof; When the discharge hole side is contacted from the outer surface side and the discharge hole side is made downstream, the discharge hole is closed while the hydraulic hole is not received from the upstream side, and when the hydraulic pressure is received from the upstream side, the discharge hole is elongated and deformed. The valve body which consists of an elastic body to open, Vent hole connected to the flow path upstream from the said valve body through a vent filter And And the elongational deformation of the valve body is achieved by a liquid pressure smaller than the fluid pressure of the vent filter, and the opening of the discharge hole is not achieved by the vent pressure from the outside to the vent filter. 9. The discharge hole according to claim 8, wherein the discharge hole is partitioned by a substantially disc shaped valve seat fixed in the discharge part and an inner wall surface of the discharge part holding the valve seat. The valve body has a substantially annular thin portion and closes the discharge hole by bringing the thin portion into contact with the valve seat from the outer surface side of the discharge portion. The thinner portion of the valve body is deformed to the downstream side when receiving the hydraulic pressure from the upstream side to open the discharge hole. 10. The discharge member according to claim 9, wherein the valve body and the discharge portion are integrally molded. A substantially cylindrical or substantially main-shaped discharge part having a bottom having a hole at the bottom, It consists of an elastic body which has the substantially annular valve body part and the substantially annular thin part formed in the front end, and fixes the said valve body part in a discharge part in the state which exposed the said thin part from the said hole out of the discharge part. Valve body, A cylindrical valve body support portion disposed in the discharge portion and partitioning the discharge hole simultaneously with the valve body; When the discharge hole side is set to the downstream side, it is provided with a ventilation hole which is connected to the flow path upstream of the valve body through the ventilation filter, When the valve body is not subjected to hydraulic pressure from the upstream side, the thin part is brought into contact with the outer peripheral surface of the valve body support part to close the discharge hole. Opening the hole, The elongational deformation of the thin portion is achieved by a liquid pressure smaller than the liquid pressure of the ventilation filter, and the opening of the discharge hole is not achieved by the ventilation pressure from the outside to the ventilation filter. 12. The valve body supporting portion according to claim 11, wherein the valve body support portion has a flange portion upstream of the circumferential portion thereof. The valve body portion of the valve body is in contact with the flange portion in a state in which no hydraulic pressure is applied from the upstream side, and closes the flow passage. When the hydraulic pressure is received from the upstream side, the valve body portion is compressed and deformed to flow between the valve body support portion. The discharge member to open the. The discharge member according to claim 11 or 12, which is formed by integrally molding the valve body and the discharge portion. The discharge member according to any one of claims 2 to 13, wherein the valve body is antibacterial. The discharge member according to any one of claims 2 to 13, wherein the discharge hole is antibacterial. The discharge member according to any one of claims 2 to 13, further comprising a fluid filter upstream of the discharge hole, or upstream of the opening and closing position of the flow path by the valve body. The container provided with the discharge member in any one of Claims 1-16 in the mouth part of a container main body. 18. The inner stopper according to claim 17, wherein an inner stopper freely slides inside the flow path of the discharge member or inside the container body, and the inner stopper is disposed on an inner wall of the flow path of the discharge member when the container is not in use. The container which abuts and closes the said flow path. 19. The container of claim 17 or 18, wherein the container is an eye drop container.