WO2001047583A1 - Check valve, and syringe using the same - Google Patents

Check valve, and syringe using the same Download PDF

Info

Publication number
WO2001047583A1
WO2001047583A1 PCT/JP2000/009179 JP0009179W WO0147583A1 WO 2001047583 A1 WO2001047583 A1 WO 2001047583A1 JP 0009179 W JP0009179 W JP 0009179W WO 0147583 A1 WO0147583 A1 WO 0147583A1
Authority
WO
WIPO (PCT)
Prior art keywords
valve body
valve
cylinder
fluid pressure
check valve
Prior art date
Application number
PCT/JP2000/009179
Other languages
French (fr)
Japanese (ja)
Inventor
Keiichi Kawakami
Hideshi Okamoto
Fujio Inoue
Original Assignee
Otsuka Pharmaceutical Factory, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Factory, Inc. filed Critical Otsuka Pharmaceutical Factory, Inc.
Priority to AU24016/01A priority Critical patent/AU2401601A/en
Publication of WO2001047583A1 publication Critical patent/WO2001047583A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/282Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3128Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/24Check- or non-return valves

Definitions

  • the present invention relates to a check valve used for a tip portion of a syringe, a co-injection port of an infusion circuit, and the like, which prevents backflow of an infusate containing a drug or the like and mixing of air bubbles, and a syringe having the check valve.
  • the catheter In order to prevent thrombus from forming in vascular catheters, the catheter is replaced with an antithrombotic agent such as heparin, but even a small amount of syringe is used to inject the antithrombotic agent.
  • an antithrombotic agent such as heparin
  • the vascular catheter becomes extremely thin
  • the antithrombotic agent in the catheter is replaced by the backflowed blood, and the antithrombotic agent is wasted.
  • the infusion liquid D flows backward because the container body 31 has resilience.
  • one valve element 81 is provided in a cylinder 80, and the valve element 81 is pushed up by a fluid pressure P by an infusate D from an upstream side to open a flow path.
  • a fluid pressure P by an infusate D from an upstream side to open a flow path.
  • 2 pieces of valve body 82 see Fig. 10
  • conical valve seat 84 conical valve seat 84
  • ball valve (ball valve) 85 and regulating protrusion 8 in cylindrical body 83 6 and the ball valve 85 is pushed up by the fluid pressure P to open the flow path
  • a mushroom valve (povet valve) 89 pressed against a valve seat 88 by a valve panel 87 is pushed up by a fluid pressure P to open a flow path (see FIG. 12).
  • the mushroom valve 89 pushed up by the fluid pressure P tends to return to the original position quickly by the action of the valve panel 87, and thus the structure shown in FIGS.
  • the effect of the backflow prevention is better than that of the one.
  • the mechanism of the valve 89 is extremely complicated, it is difficult to obtain a product of stable quality, and the incidence of defective products is high.
  • an object of the present invention is to provide a check valve capable of reliably preventing backflow of an infusate containing a drug or the like and mixing of bubbles, and reliably preventing backflow of the infusate and mixing of bubbles. And a syringe that can be used.
  • the valve body is arranged inside the cylinder to close off the flow of the infusate, and is easily compressed and deformed when receiving fluid pressure from the upstream side of the cylinder, and between the valve seat and the inner wall of the cylinder.
  • the valve body and the valve seat or the inner wall of the cylinder are formed to form a cavity and allow the infused liquid to flow through the cavity, and the direction in which the fluid pressure is applied to the valve body, and the valve body is compressed When it is deformed, it is arranged so that the direction in which the infusion liquid flows into the gap portion intersects.
  • the valve body is easily compressed and deformed by the fluid pressure from the upstream side of the cylindrical body. For this reason, for example, when a syringe for a syringe is connected to the upstream side of the check valve and pressure is applied from the piston to the infusate in the syringe, that is, if fluid pressure is applied from the upstream side of the cylinder, However, a compression deformation occurs in the valve body, a gap is formed between the valve body and the inner wall of the cylinder, and the infusate is discharged to the downstream side through the gap.
  • the valve body when the load from the biston is stopped, that is, when the load of the fluid pressure is stopped, the valve body returns to the original shape and the gap disappears.
  • the direction of the operation of the valve body to return to the original shape that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure
  • the infused liquid or the like is in the gap.
  • Intersect preferably orthogonal
  • the valve element moves in the same direction as the direction in which the fluid flows, a phenomenon occurs in which the fluid moves (that is, reverse flow) along with the return operation (restoring operation) of the valve.
  • the check valve of the present invention as described above, the restoring operation of the valve body and the injection Since the flowing direction of the liquid intersects with each other, the phenomenon that the infused liquid flows backward can be suppressed to a very high degree.
  • the amount is only very small, causing the problem of causing air embolism as in the past and replacing all the infusion in the vascular catheter. The possibility of causing problems such as sacrifice is also sufficiently suppressed.
  • the check valve of the present invention despite having a very simple structure, a valve body made of an elastic body that can be easily deformed by fluid pressure is provided inside the cylindrical body. In addition, it is possible to reliably prevent the backflow of the injection liquid and the incorporation of bubbles. Therefore, the check valve of the present invention is suitably used, for example, in the field of medical devices and the like, for example, at the tip of a syringe, a co-infusion port of an infusion circuit, and the like.
  • the infusion liquid flow hole is closed by the valve body when not receiving the fluid pressure, and is opened when receiving the fluid pressure to form a gap formed between the valve body and the valve seat.
  • valve body is characterized in that the movement of the cylinder body to the downstream side is restricted by a locking portion abutting on the downstream side of the valve body (first preferred embodiment);
  • valve element is disposed in sliding contact with the inner wall of the cylinder
  • the cylindrical body has, on its inner wall, one or more concave notches extending in the axial direction of the cylindrical body,
  • the concave portion is exposed to the inside of the tubular body on the downstream side of the tubular body, and is closed by the valve body when not receiving the fluid pressure on the upstream side of the tubular body, and receives the fluid pressure. Sometimes it is exposed inside the cylinder, forms a gap between the valve body and the inner wall of the cylinder, and becomes a flow path for the infusate.
  • the valve body is characterized in that the movement of the cylinder body to the downstream side is restricted by a locking portion abutting on the downstream side of the valve body (second preferred embodiment).
  • the valve body is in contact with the valve seat on the upstream side of the cylinder, and is in contact with the locking portion on the downstream side of the cylinder, and the fluid from the upstream side of the cylinder is Compressed by pressure Although deformed, the tubular body itself is held between the valve seat and the locking portion without moving downstream.
  • a gap is formed between the valve body and the valve seat, and the gap passes through the infusate flow hole provided in the valve seat and the gap. Then, the injection liquid is discharged to the downstream side of the cylinder. On the other hand, when the load of the fluid pressure is stopped, the valve body returns to the original shape, the gap disappears, and the injection liquid flow hole is closed by the valve body.
  • the direction of the movement of the valve body to return to the original shape (that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure) is such that the infused liquid flows into the gap. Therefore, according to the first preferred embodiment, the phenomenon in which the fluid tends to flow backward can be suppressed to a very high degree.
  • the valve element is disposed in sliding contact with the inner wall of the cylinder, abuts on the locking portion on the downstream side of the valve element, and is compressed and deformed by fluid pressure from the upstream side of the cylinder.
  • the cylinder itself is held in the cylinder without moving downstream.
  • a concave notch provided in the inner wall of the cylinder at the downstream side of the cylinder is exposed to the inside of the cylinder, and a gap between the valve element and the inner wall of the cylinder is formed. A void is formed in the gap.
  • the infusate in the cylinder passes through the concave portion and is discharged downstream.
  • the valve body when the load of the fluid pressure is stopped, the valve body returns to the original shape, the concave notch portion is closed on the downstream side of the cylindrical body, and the gap disappears.
  • the direction of the movement of the valve body to return to the original shape that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure
  • the phenomenon in which the fluid tends to flow backward can be suppressed to a very high degree.
  • a syringe according to the present invention includes the check valve according to the present invention, and directly or indirectly connects an injector to a downstream open end of the cylinder of the check valve, or integrally integrates the injector. It is characterized by having been formed.
  • the above-mentioned syringe of the present invention comprises a syringe needle or an injection port directly at the downstream open end of the cylindrical body in the check valve of the present invention, or through a hollow adapter or the like as necessary. Or the like, or integrally with the injection device directly or via a hollow adapter or the like as needed at the downstream open end of the cylinder of the check valve according to the present invention. What is formed.
  • the check valve according to the present invention since the check valve according to the present invention is provided, there is no possibility that a backflow of an infusate or the like or mixing of bubbles will occur during use. Therefore, it can be widely used in the medical field and the like as a safe syringe which does not cause the above-mentioned problems such as air embolism.
  • the syringe according to the present invention has a point connected to the inner wall of the cylinder upstream of the valve body in the cylinder, or connected to the infusion liquid flow hole upstream of the valve seat, and having a pointed tip on the upstream side of the cylinder.
  • a hollow puncture needle may be provided.
  • the syringe according to the present invention may be one in which a flexible plastic infusion container is directly or indirectly and slidably fitted to the upstream open end of the cylindrical body. Good.
  • an infusion solution container made of a flexible plastic and squeezing the container body to discharge the injection solution is provided directly at the upstream open end of the cylindrical body, or a hollow adapter as necessary. And may be slidably (slidably) fitted through the cover.
  • FIG. 1 is a partially cutaway perspective view showing one embodiment of a check valve according to the present invention, and FIG. 1a shows a state in which fluid pressure is not applied to the valve body 12 from a cylinder upstream side U, Figure lb shows the condition with fluid pressure P applied.
  • FIG. 2 is a cross-sectional view of the check valve 10 shown in FIG. La, wherein FIG. 2a is a cross-sectional view taken along the line AA, and FIG. 2b is a cross-sectional view taken along the line BB.
  • FIG. 3 is a longitudinal sectional view of the check valve 10 shown in FIGS. La and lb, and FIG. Fig. 3b shows a state in which fluid pressure is not applied to the valve body 12 from the upstream side U, and Fig. 3b shows a state in which fluid pressure P is applied.
  • FIG. 4 is a partially cutaway perspective view showing another embodiment of the check valve according to the present invention, and FIG. 4a shows a state in which fluid pressure is not applied from the upstream side U of the cylindrical body to the valve body 22, FIG. 4b shows a state where the fluid pressure P is applied.
  • FIG. 5 is a cross-sectional view of the check valve 20 shown in FIG. 4a, and is a cross-sectional view taken along line AA of FIG. 4a.
  • Fig. 6 is a longitudinal sectional view of the check valve 20 shown in Figs. 4a and 4b.
  • Fig. 6a shows a state in which fluid pressure is not applied from the upstream side U of the cylinder to the valve body 22, and Fig. Shows the state where pressure P is applied.
  • FIG. 7 is a plan view showing one embodiment of a syringe provided with a check valve of the present invention.
  • FIG. 8 is a plan view showing another embodiment of the syringe provided with the check valve of the present invention.
  • FIG. 9 is a longitudinal sectional view showing an example of a conventional check valve.
  • FIG. 10 is a longitudinal sectional view showing an example of a conventional check valve.
  • FIG. 11 is a longitudinal sectional view showing an example of a conventional check valve.
  • FIG. 12 is a longitudinal sectional view showing an example of a conventional check valve.
  • the check valve of the present invention comprises: (a) a cylindrical body; and (b) a flow path that is disposed inside the cylindrical body to block the flow of the infusate, and to reduce fluid pressure from the upstream side of the cylindrical body.
  • a valve body made of an elastic body, wherein the valve body is easily deformed by compression upon receipt of the valve body to form a gap between the valve body and the inner wall of the cylinder.
  • the valve body, the valve seat or the inner wall of the cylinder are configured such that a direction in which fluid pressure is applied to the valve body, and a direction in which the injection liquid flows into the gap when the valve body is compressed and deformed. And are arranged to intersect each other.
  • FIGS. 1 to 3 corresponds to an example according to the first preferred embodiment.
  • FIG. 1 is a partially cutaway perspective view showing an embodiment of a check valve according to the present invention
  • FIG. 1a shows a state in which fluid pressure is not applied to a valve body 12 from a cylinder upstream side U.
  • Fig. B shows a state in which the fluid pressure P is applied.
  • FIG. 2 is a cross-sectional view of the check valve 10 shown in FIG. La, wherein FIG. 2A is a cross-sectional view taken along the line AA, and FIG. 2B is a cross-sectional view taken along the line BB.
  • FIG. 3 is a longitudinal sectional view of the check valve 10 shown in FIGS. La and lb.
  • FIG. 3a shows a state in which fluid pressure is not applied from the upstream side U of the cylinder to the valve body 12 (that is, FIG. 1a)
  • FIG. B shows a state in which the fluid pressure P is applied (that is, a vertical sectional view of FIG. Lb).
  • Each vertical cross-sectional view in FIG. 3 is a cross-sectional view taken along line CC in FIG. 2A.
  • the check valve 10 shown in FIG. 1 to FIG. 3 is provided inside a cylindrical body 11 which is a flow path of the injection liquid D (omitted in FIG. La), for example, as shown in FIG. 1 a and FIG.
  • a valve body 12 made of an elastic body and arranged in contact with the valve seat 13.
  • the movement of the valve body 12 to the downstream side L is restricted by the locking portion 16 abutted on the valve body 12 at the downstream side L of the cylinder body. Have been.
  • a void portion 14 is formed between the valve body 12 and the valve seat 13, and injection is performed.
  • the injection liquid D can be discharged through the liquid flow holes 15 and the voids 14.
  • the valve body 12 returns to the original state (ie, the state shown in Fig. La and Fig. 3a), and the void part 14 disappears.
  • the injection liquid flow hole 15 is closed by the valve body 12.
  • the direction of the fluid pressure P applied to the valve body 12 coincides with the direction of operation when the valve body 12 is compressed and deformed, and is coaxial with the direction of operation when the valve body 12 is restored (axial direction X). It's above.
  • the direction y (see FIG. 3 b) in which the injection liquid D flows into the void portion 14 generated by the compression deformation of the valve body 12 is the same as the direction in which the fluid pressure P is applied to the valve body 12 described above. They are not coaxial but intersect each other (preferably orthogonal).
  • valve element returns to its original shape (position).
  • the problem that is remarkable in the conventional check valve when the gas flows backward to the upstream side, is highly suppressed. Even if the backflow of the injection solution D occurs, the amount is only extremely small. That is, according to the check valve 10 shown in FIGS. 1 to 3, the backflow phenomenon caused by the opening and closing of the valve body 12 can be extremely suppressed.
  • a hollow puncture needle having a pointed end 17 at the upstream side U of the cylindrical body is communicated with the injection liquid flow hole 15 on the upstream side of the valve seat 13. 18 are provided.
  • a puncture needle 30 that is sealed and filled with an infusion solution is inserted from the upstream open end 11 U of the cylindrical body 11 to seal the infusion solution. Open the end of the filled container just before using it for actual use
  • the locking portion 16 is not limited to a rib-shaped member as shown in FIG. 1.
  • the cylindrical body of the valve body 12 is formed on the inner surface of the cylindrical body 11, the cylindrical body of the valve body 12 is formed. It may be a protruding shape provided to be brought into contact with the downstream side L (specifically, a locking portion 26 shown in FIG. 4). Further, it may be a net-shaped member provided so as to be in contact with the downstream side L of the valve body 12.
  • FIGS. 4 to 6 corresponds to an example according to the second preferred embodiment.
  • FIG. 4 is a partially cutaway perspective view showing another embodiment of the check valve according to the present invention.
  • FIG. 4A shows a state in which fluid pressure is not applied to the valve body 22 from the upstream side U of the cylindrical body.
  • Fig. B shows a state where the fluid pressure P is applied.
  • FIG. 5 is a cross-sectional view of the check valve 20 and is a cross-sectional view taken along the line AA of FIG. 4A.
  • Fig. 6 is a longitudinal sectional view of the check valve 20 shown in Figs. 4a and 4b.
  • Fig. 6a shows a state in which fluid pressure P is not applied from the upstream side U of the cylinder to the valve body 22 ( That is, FIG. 4a shows a vertical cross-sectional view)
  • FIG. B shows a state in which a fluid pressure P is applied
  • a vertical cross-sectional view of FIG. 6 are cross-sectional views taken along line BB shown in FIG.
  • the check valve 20 shown in FIGS. 4 to 6 is, for example, as shown in FIGS.
  • valve body 22 made of an elastic body and provided in sliding contact with the inner wall 23 of the cylinder is provided.
  • the valve body 22 is connected to the downstream side L (the side on which the infused liquid D flows out) of the valve body 22 by a locking portion (projection) 26 abutted against the valve body 22 at the downstream side L of the cylinder body. Movement is regulated.
  • the valve body 22 is formed by applying a fluid pressure P from the upstream side U of the cylindrical body, specifically, by injecting an infusate container (syringe) 30 made of a flexible plastic as shown in FIG. To the upstream open end 21 U of the container and apply the fluid pressure P by crushing the container body 31, or the injection liquid container (syringe) 50 for a syringe as shown in FIG. By being connected to the open end 21 U and applying a fluid pressure P using the piston 51, it is easily compressed and deformed to form a void 24 between the inner wall 23 of the cylinder.
  • a fluid pressure P from the upstream side U of the cylindrical body
  • the valve element 22 is brought into the state shown in FIGS. 4B and 6B by compression deformation. That is, due to the compressive deformation of the valve body 22 caused by the load of the fluid pressure P from the upstream side U of the cylindrical body, the starting end 25 U of the concave portion 25 (see FIG. 4A and FIG. 6A) becomes cylindrical. A cavity 24 is formed between the valve body 22 and the inner wall 23 of the cylinder (particularly, the inner surface of the recessed portion 25), and the injection solution D is formed through the cavity 24. Can be discharged. On the other hand, when the application of the fluid pressure P to the valve body 22 is stopped, the valve body 22 returns to the original state (that is, the state shown in FIGS. 4A and 6A), and the starting end of the concave notch 25 While 25 U is closed, the void 24 disappears.
  • Fluid pressure applied to the valve element 22 The direction of P coincides with the direction of operation when the valve element 22 is compressed and deformed, and is coaxial with the direction of operation when the valve element 22 is restored (axial direction X). )It's above.
  • the direction y (see FIGS. 4 b and 6 b) in which the infusate D flows into the gap 24 formed by exposing the starting end 25 U of the concave notch 25 to the inside of the cylinder.
  • the valve body 22 is not coaxial with the direction in which the fluid pressure P is applied to the valve body 22 and intersects (preferably, orthogonally) with each other.
  • a locking portion 26U may be provided on the upstream side. In this case, the movement of the valve body 22 to the upstream side U of the cylindrical body can be restricted.
  • the locking portions 26 and 26 U are not limited to protrusions as shown in FIGS. 4 and 6, for example, in the axial direction X of the cylindrical body 21. It may be an extending rib-shaped member (specifically, a locking member 16 shown in FIG. 1). In this case, the formation process can be simplified, for example, the locking portion can be formed by integral molding with the cylinder 21, and the advantage of reinforcing the strength of the cylinder 21 can be obtained. Further, the locking portions 26 and 26 U may be a net-like member provided so as to be in contact with the upstream side U or the downstream side L of the valve body 12.
  • the elastic body used as the valve body in the check valve of the present invention is soft enough to be easily deformable by the fluid pressure of the infusate generated by, for example, pressing the piston of the syringe, and does not apply fluid pressure. It is not particularly limited except that it retains its shape in the state, for example, it shows properties as a gel.
  • an elastic body examples include rubbers such as natural rubber, silicone rubber, isoprene rubber, butadiene rubber, and fluororubber; plastics such as polyethylene and polypropylene; various thermoplastic elastomers; Is sufficiently low, and shows properties sufficiently as a gel.
  • a thermoplastic elastomer is preferably used.
  • thermoplastic elastomer is, for example, styrene-ethylene / butylene-styrene-block copolymer (SEBS), styrene-butadiene-styrene block copolymer (SBS), styrene-isoprene-styrene block copolymer.
  • SEBS styrene-ethylene / butylene-styrene-block copolymer
  • SBS styrene-butadiene-styrene block copolymer
  • SBS styrene-isoprene-styrene block copolymer
  • SIS styrene-ethylene / propylene-styrene block copolymer
  • SEPS styrene-ethylene / propylene-styrene block copolymer
  • SEB styrene-ethylene / butylene block copolymer
  • SEP ethylene and propylene block Olefin elastomers
  • polymers polyurethane elastomers; and mixtures thereof.
  • the diameter of the elastic body is determined by the length of the elastic body according to the inner diameter of the cylinder constituting the check valve.
  • the length may be appropriately set according to the length, position, and the like of the concave portion.
  • the elastic body that is, the valve body
  • the swelling in the diametrical direction becomes too large when the elastic body is compressed, and there is a possibility that the recessed portion is closed.
  • the elastic body is too small, sufficient compressive deformation may hinder the flow of the fluid. For this reason, the size of the elastic body must be set in consideration of the degree of compressive deformation.
  • the elastic body due to fluid pressure for example, hardness, tensile stress, compression elastic modulus and the like of the elastic body can be mentioned.
  • the hardness of the elastic body used in the present invention is JISA hardness [spring hardness ⁇ ⁇ s ( ⁇ type) measured by the method described in “JISK 631-5.2“ Spring hardness test ”). It is preferably from 0 to 20 and more preferably from 0 to 10. If the hardness of the elastic body exceeds the above range, the elastic body may be too hard and may not be sufficiently deformed by the fluid pressure. On the other hand, the lower limit of hardness is limited to the above value in order to maintain the shape when no fluid pressure is applied.
  • the elastic material used in the present invention preferably has a tensile stress ⁇ loo (MPa) JISK 6251] at an elongation of 100% of 0.05 to 2.0 MPa. More preferably, it is in the range of 0.05 to 0.5 MPa.
  • the elastic body may not be deformed by the fluid pressure. Conversely, if the tensile stress of the elastic body falls below the above range, the elastic body may not be fully restored after the fluid pressure is removed.
  • its compression set CS (%) [JISK6301, measurement conditions: 70 ° C x 22 hours] is preferably 30 or less.
  • a foam however, one having discontinuous pores and not causing liquid leakage
  • an additive may be used. It is also possible to adopt a material adjusted to satisfy the above-described properties.
  • An example of such a material is a commercially available silicone-urethane gel (trade name: Chemitech Gel (manufactured by Chemitech)) to which a general-purpose additive is appropriately added (cylindrical body).
  • the cylinder in the check valve of the present invention may be, for example, a polyolefin such as polyethylene, polypropylene, poly-4-methylpentene [for example, trade name “TPX” of Mitsui Chemicals, Inc.] used for conventional syringes and the like; Polycyclic olefins such as cyclododecene copolymer (trade name “Abel” of Mitsui Chemicals, Inc.); acrylonitrile-butadiene-styrene copolymer (ABS); polyethylene naphthylate ( ⁇ ⁇ ⁇ ), polyethylene tereph It is formed of various plastics, such as polyester such as evening rate ( ⁇ ⁇ ⁇ ) and polyarylate; and benzene-based polymer such as polyphenylene sulfide (PPS).
  • TPX trade name “TPX” of Mitsui Chemicals, Inc.”
  • Polycyclic olefins such as cyclodode
  • the number, length, width, and the like of the injection liquid flow passages provided on the inner surface of the cylindrical body are not particularly limited, and the flow of the injection liquid or the like is sufficiently large to prevent the backflow of the injection liquid and the like. It is set appropriately so that the infused liquid and the like can be smoothly discharged when the fluid pressure is applied to the elastic body from the side.
  • the cylinder in the check valve of the present invention is formed by, for example, injection molding, extrusion molding, or the like, from the opening end 11 U of the cylinder upstream side U to the valve seat 13. After arranging the valve body 12 on the valve seat 13, heat both cylinders together with the downstream opening end 11 L side cylinder separately formed by injection molding, extrusion molding, etc. It is manufactured by fixing by welding, ultrasonic welding, fitting, assembling, etc. (see Fig.
  • valve In addition to the above manufacturing method, after the entire cylinder is integrally molded, the valve It is also possible to adopt a method of inserting the inside.
  • the syringe according to the present invention includes the check valve according to the present invention, and a syringe directly or indirectly connected to a downstream open end of the cylindrical body of the check valve.
  • a check valve of the present invention is provided, and a syringe is integrally formed at a downstream opening end of a cylindrical body of the check valve.
  • FIGS. 7 and 8 corresponds to a syringe provided with the above-described check valve of the present invention.
  • a flexible plastic infusion container (syringe) 30 sealed and filled with an infusion solution is connected to the upstream opening end 1 of the cylinder 11 in the check valve 10 of the present invention. Directly connected to 1 U.
  • the infusate container (syringe) 30 is formed by crushing the container body 31 and deforming it into the shape shown by the dotted line in FIG. Is to be discharged.
  • Such an infusion solution container (syringe) 30 has advantages in that it has few components for discharging the infusion solution, is easy to manufacture, and maintains hermeticity during storage.
  • the infusate container (syringe) 30 may be indirectly connected to the upstream open end 11 U, for example, through an adapter, or However, it may be formed integrally with the upstream opening end 11U.
  • a syringe 41 having a syringe needle 40 is directly connected to a downstream open end 21 L of a cylindrical body 21 of a check valve 20, and an upstream open end 21 is provided.
  • An infusion solution container (syringe) 50 sealed and filled with an injection solution is indirectly connected to U via an adapter 60 having a puncture needle 61.
  • the injection device 41 may be indirectly connected to the downstream open end 21 L via an adapter or the like, or may be integrally formed with the downstream open end 21 L. It may be.
  • the injection liquid container (syringe) 50 discharges the injection liquid filled in the syringe 50 by applying pressure to the piston 51.
  • the infusate container (syringe) 50 although the infusate and the like may flow backward when pressurization of the piston 51 is stopped, according to the syringe shown in FIG. 8, the infusate container (syringe) 50 Since the check valve 20 of the present invention is connected further downstream, the problem that the infusate flows backward can be highly suppressed.
  • the infusion solution container (syringe) 50 may be directly connected to the upstream open end 21 U without passing through the adapter 60 shown in FIG.
  • a puncture needle 61 having a point 62 on the upstream side 21 U of the cylindrical body is provided so as to be connected to the inner wall of the cylindrical body of the adapter 60.
  • a puncture needle 61 By using such a puncture needle 61, the tip of the syringe 50 can be opened (opened) immediately before it is actually used. Therefore, air bubbles and various bacteria can be prevented from being mixed into the infusion solution, and the convenience during use can be improved.
  • the injection liquid container (syringe) 50 may be formed integrally with the upstream open end 21U.
  • the injecting device used for the syringe of the present invention is not particularly limited except that it is hollow, and may be either a double-ended needle or a device having a sharpened portion only at one end. Good. Further, it may be a metal needle or a plastic needle, and these may be appropriately selected depending on the use of the syringe.
  • the injection needle is made of plastic, the injection tool can be directly connected to the cylinder of the check valve of the present invention to be integrally formed.
  • the same syringes and bistones as those conventionally known can be used for accommodating the infusion solution.
  • check valve and the syringe according to the present invention are not limited to those described above, and the design can be appropriately changed within a range that does not impair the object, operation and effect of the present invention.
  • check valve according to the present invention is applicable not only to the medical syringe described above, but also to various devices that need to prevent backflow of fluid and mixing of air bubbles. Can be. Industrial applications
  • the syringe of the present invention is provided with the check valve, there is no danger of backflow of the infusate, mixing of air bubbles, etc. during use. Therefore, it can be widely used in the medical field and the like as a safe syringe without causing the aforementioned problems such as air embolism.

Abstract

A check valve comprising a valve seat (13) having an injection liquid passage hole (15), and a valve disk (12) contacted with the valve seat (13), the valve seat and the valve disk being disposed internally of a cylinder (11) to define a void (14) for passing injection liquid (D) by producing compressive deformation in the valve disk (12) by a fluid pressure (P) from the upstream side (U) of the cylinder in a direction (an inflow direction (y)) crossing a direction (an axial direction (X)) in which the fluid pressure (P) acts on the valve disk (12); and a syringe having such check valve. It is possible to reliably prevent the backflow of an injection liquid containing a medicine or the like and the mixing of bubbles into the injection liquid, which would attend such backflow.

Description

明 細 書 逆止弁およびそれを用いた注射器 技術分野  Description Non-return valve and syringe using the same
本発明は、 注射器の先端部分や輸液回路の混注口等に用いられる、 薬剤等を含 有する注入液の逆流および気泡の混入を防止した逆止弁と、 当該逆止弁を有する 注射器とに関する。 背景技術  The present invention relates to a check valve used for a tip portion of a syringe, a co-injection port of an infusion circuit, and the like, which prevents backflow of an infusate containing a drug or the like and mixing of air bubbles, and a syringe having the check valve. Background art
従来、 例えば、 注射器のピストンに圧力をかけることによって当該注射器内の 注入液を患者に直接投与したり、 あるいは輸液回路を介して点滴用チューブゃ力 テーテル内に混入する操作は広く行われており、さらに、かかる操作に際しては、 注射器の使用直前にピストンを押圧して、 当該注射器内の空気を完全に排出させ る処理が行われている。  Conventionally, for example, the operation of directly injecting the infusate in the syringe by applying pressure to the piston of the syringe to the patient, or mixing it into the drip tube via the infusion circuit has been widely performed. Further, in such an operation, a process is performed in which the piston is pressed immediately before use of the syringe to completely discharge the air in the syringe.
ところが、 かかる処理を行う際には、 押圧の具合によって空気の排出が不完全 になったり、 外気の混入が生じたりしてしまい、 注入液中に気泡が残存するとい う問題があった。  However, when performing such treatment, there has been a problem that the air is incompletely discharged or the outside air is mixed in due to the degree of pressing, and air bubbles remain in the infusate.
特に、 注入液中に残存した気泡が注入液とともに誤って静脈内等に注射される と空気閉栓症という重大な問題を引き起こすおそれがあるので、 空気の排出操作 は慎重に行われなければならない。  In particular, if air bubbles remaining in the infusion are mistakenly injected into the vein, etc. together with the infusion, serious problems such as air embolism may be caused. Therefore, the air must be evacuated carefully.
しかしながら、 図 7に示すような、 可撓性プラスチック容器本体 3 1を押しつ ぶして注入液 Dを吐出させるタイプの注射器 (注入液容器) 3 0では、 押圧の極 めてわずかな加減が空気の排出に大きな影響を与えるという問題があり、 さらに 容器自体が有する復元性のために注入液の逆流や空気の混入が生じ易くなるので、 空気の排出操作は困難を極めていた。  However, as shown in FIG. 7, in the syringe (injection container) 30 of the type that crushes the flexible plastic container body 31 and discharges the infusion D, the pressure is extremely small. There is a problem that this has a great effect on the discharge of air, and further, because of the resilience of the container itself, the backflow of the infusate and the incorporation of air are likely to occur, making the operation of discharging air extremely difficult.
また、 血管カテーテル内での血栓の発生を防止するために、 カテーテル内をへ パリン等の抗血栓剤で置換することが行われているが、 抗血栓剤を注入するため の注射器にほんの少しでも逆流が生じると、 血管カテーテルが極めて細い部材で あるためにカテーテル内の抗血栓剤が逆流した血液によって置換されてしまい、 抗血栓剤が無駄になってしまう。 とりわけ、 図 7に示すような、 容器本体 3 1を 押しつぶして注入液 Dを吐出させるタイプの注射器を用 t、た場合は、 容器本体 3 1が復元性を有するために、 注入液 Dが逆流する傾向が大きく、 上記の問題が顕 著であった。 In order to prevent thrombus from forming in vascular catheters, the catheter is replaced with an antithrombotic agent such as heparin, but even a small amount of syringe is used to inject the antithrombotic agent. When reflux occurs, the vascular catheter becomes extremely thin As a result, the antithrombotic agent in the catheter is replaced by the backflowed blood, and the antithrombotic agent is wasted. In particular, when a syringe of a type that squeezes the container body 31 and discharges the infusion liquid D as shown in Fig. 7 is used, the infusion liquid D flows backward because the container body 31 has resilience. The above problems were prominent.
従来、 一般に流体の逆流を防止することを目的として、 種々の逆止弁が提供さ れている。  Conventionally, various check valves have been provided for the purpose of generally preventing backflow of a fluid.
かかる逆止弁としては、 筒体 8 0中に 1枚の弁体 8 1を設けて、 上流側からの 注入液 Dによる流体圧 Pで弁体 8 1を押し上げて、 流路を開放させるもの (図 9 参照)、 弁体 8 2を 2枚にしたもの (図 1 0参照)、 筒体 8 3中に円錐形の弁座 8 4、 玉弁 (ボールバルブ) 8 5および規制用突起 8 6とを設け、 流体圧 Pによつ て玉弁 8 5を押し上げて流路を開放させるもの (実閧昭 5 8— 1 2 0 7 4 8号公 報, 図 1 1参照)、 および、 弁パネ 8 7によって弁座 8 8に押え付けられたきのこ 弁(ポベット弁) 8 9を流体圧 Pによって押し上げて、流路を開放させるもの(図 1 2参照) が知られている。  As such a check valve, one valve element 81 is provided in a cylinder 80, and the valve element 81 is pushed up by a fluid pressure P by an infusate D from an upstream side to open a flow path. (See Fig. 9), 2 pieces of valve body 82 (see Fig. 10), conical valve seat 84, ball valve (ball valve) 85, and regulating protrusion 8 in cylindrical body 83 6 and the ball valve 85 is pushed up by the fluid pressure P to open the flow path (see Publication No. 58-120748, see FIG. 11), and It is known that a mushroom valve (povet valve) 89 pressed against a valve seat 88 by a valve panel 87 is pushed up by a fluid pressure P to open a flow path (see FIG. 12).
しかしながら、 上記従来の逆止弁のうち、 図 9、 図 1 0および図 1 1に示すも のでは、 流体圧 Pによって開放された弁 8 1 , 8 2 , 8 5が再び流路を閉鎖すベ く元の位置まで戻る際に、 多少なりとも注入液 Dが逆流してしまうという問題が ある。 特に、 図 9および図 1 0に示す機構のものではかかる問題が顕著である。 図 1 1に示す機構によれば、 弁 8 5の構造は極めて簡易なものとなるものの、 依然として流路の閉鎖が不完全になり易く、 図 9および図 1 0に示す機構のもの と同様に、 逆流が生じるおそれが大きい。  However, among the above conventional check valves, those shown in FIGS. 9, 10, and 11, the valves 81, 82, 85 opened by the fluid pressure P close the flow passage again. When returning to the original position, there is a problem that the injection liquid D flows back to some extent. In particular, in the mechanism shown in FIGS. 9 and 10, such a problem is remarkable. According to the mechanism shown in FIG. 11, although the structure of the valve 85 is extremely simple, the closing of the flow passage is still apt to be incomplete, so that the valve 85 is similar to the mechanism shown in FIG. 9 and FIG. There is a great possibility that backflow will occur.
一方、 図 1 2に示す機構によれば、 流体圧 Pによって押し上げられたきのこ弁 8 9は、 弁パネ 8 7の作用によって素早く元の位置に戻ろうとするため、 図 9お よび図 1 0のものに比べて逆流防止の効果が良好である。 しかしながら、 弁 8 9 の機構が極めて複雑であるために安定した品質の製品が得られにくく、 不良品の 発生率が高い。 また、 極めてサイズの小さい弁 8 9を製造するのは困難で、 部品 数が多いことも相俟って、 コス卜が高くなる問題もあった。  On the other hand, according to the mechanism shown in FIG. 12, the mushroom valve 89 pushed up by the fluid pressure P tends to return to the original position quickly by the action of the valve panel 87, and thus the structure shown in FIGS. The effect of the backflow prevention is better than that of the one. However, since the mechanism of the valve 89 is extremely complicated, it is difficult to obtain a product of stable quality, and the incidence of defective products is high. In addition, it was difficult to manufacture a valve 89 having an extremely small size, and there was also a problem that the cost was high due to the large number of parts.
また、 前述の空気閉栓症や、 血管カテーテル内での血栓の発生は、 気泡や血液 の極めてわずかな混入によっても発生するおそれがあるため、 逆流をより一層確 実に防止することが求められている。 発明の開示 In addition, the aforementioned air embolism and the generation of blood clots in vascular catheters There is a possibility that even a very small amount of water may be mixed in, so it is required to prevent backflow more reliably. Disclosure of the invention
そこで本発明の目的は、 薬剤等を含有する注入液の逆流および気泡の混入を確 実に防止することのできる逆止弁と、 前記注入液の逆流および気泡の混入が生じ るのを確実に防止することのできる注射器とを提供することである。  Therefore, an object of the present invention is to provide a check valve capable of reliably preventing backflow of an infusate containing a drug or the like and mixing of bubbles, and reliably preventing backflow of the infusate and mixing of bubbles. And a syringe that can be used.
上記課題を解決するための本発明に係る逆止弁は、  The check valve according to the present invention for solving the above-mentioned problems,
少なくとも、 筒体と、 弾性体からなる弁体と、 を備えており、 At least a cylindrical body and a valve body made of an elastic body,
前記弁体は、 筒体内部に配置されて注入液の流通を閉止し、 かつ、 筒体上流側か ら流体圧を受けると容易に圧縮変形して、 弁座または筒体内壁との間に空隙部を 形成するとともに、 当該空隙部を通じて注入液を流通させるものであって、 前記弁体と、 弁座または筒体内壁とは、 弁体に前記流体圧がかかる方向と、 弁体 が圧縮変形した際に、 前記空隙部に注入液を流入させる方向と、 を交差させるよ うに配置されていることを特徴とする。 The valve body is arranged inside the cylinder to close off the flow of the infusate, and is easily compressed and deformed when receiving fluid pressure from the upstream side of the cylinder, and between the valve seat and the inner wall of the cylinder. The valve body and the valve seat or the inner wall of the cylinder are formed to form a cavity and allow the infused liquid to flow through the cavity, and the direction in which the fluid pressure is applied to the valve body, and the valve body is compressed When it is deformed, it is arranged so that the direction in which the infusion liquid flows into the gap portion intersects.
上記本発明の逆止弁において、 弁体は、 筒体上流側からの流体圧によって容易 に圧縮変形するものである。 このため、 例えば、 逆止弁の上流側に注射器用のシ リンジを接続して、 当該シリンジ内の注入液にビストンから圧をかけると、 すな わち筒体上流側から流体圧をかけると、 弁体に圧縮変形が生じて、 弁座または筒 体内壁との間に空隙部が形成され、 当該空隙部を通過して下流側へ注入液が排出 される。  In the check valve of the present invention, the valve body is easily compressed and deformed by the fluid pressure from the upstream side of the cylindrical body. For this reason, for example, when a syringe for a syringe is connected to the upstream side of the check valve and pressure is applied from the piston to the infusate in the syringe, that is, if fluid pressure is applied from the upstream side of the cylinder, However, a compression deformation occurs in the valve body, a gap is formed between the valve body and the inner wall of the cylinder, and the infusate is discharged to the downstream side through the gap.
一方、 ビストンからの負荷を止めると、 すなわち流体圧の負荷を止めると、 弁 体が元の形状に戻って前記空隙部が消滅する。 この際、 弁体が元の形状に戻ろう とする動作の方向 (すなわち、 弁体にかかる流体圧と同軸上にあって、 流体圧と は逆向きの方向)は注入液等が空隙部に流入する方向と交差(好ましくは、 直交) する。  On the other hand, when the load from the biston is stopped, that is, when the load of the fluid pressure is stopped, the valve body returns to the original shape and the gap disappears. At this time, the direction of the operation of the valve body to return to the original shape (that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure) is such that the infused liquid or the like is in the gap. Intersect (preferably orthogonal) with the incoming direction.
従来の逆止弁においては、 流体が流れる方向と同一の方向に弁体が移動し、 弁 の戻り動作 (復元動作) とともに流体が移動 (すなわち、 逆流) する現象が生じ ていたものの、 上記本発明の逆止弁によれば、 前述のように弁体の復元動作と注 入液が流れる方向とが互いに交差するため、 注入液が逆流する現象を極めて高度 に抑制することができる。 また、 たとえ注入液の逆流が生じたとしても、 その量 は極めて微量にしか過ぎないことから、 従来のような空気閉栓症を引き起こすと いった問題や、 血管カテーテル内の注入液が全て置換されてしまうといった問題 を引き起こすおそれも、 十分に抑制されている。 In the conventional check valve, although the valve element moves in the same direction as the direction in which the fluid flows, a phenomenon occurs in which the fluid moves (that is, reverse flow) along with the return operation (restoring operation) of the valve. According to the check valve of the present invention, as described above, the restoring operation of the valve body and the injection Since the flowing direction of the liquid intersects with each other, the phenomenon that the infused liquid flows backward can be suppressed to a very high degree. In addition, even if the infusion flows back, the amount is only very small, causing the problem of causing air embolism as in the past and replacing all the infusion in the vascular catheter. The possibility of causing problems such as sacrifice is also sufficiently suppressed.
従って、 上記本発明の逆止弁によれば、 筒体の内部に、 流体圧によって容易に 変形可能な弾性体からなる弁体を設けた、 極めて簡易な構造のものであるにもか かわらず、注入液の逆流や気泡の混入を確実に防止することができる。それゆえ、 本発明の逆止弁は、 例えば注射器の先端部分や輸液回路の混注口など、 特に医療 用具等の分野において好適に使用される。  Therefore, according to the check valve of the present invention described above, despite having a very simple structure, a valve body made of an elastic body that can be easily deformed by fluid pressure is provided inside the cylindrical body. In addition, it is possible to reliably prevent the backflow of the injection liquid and the incorporation of bubbles. Therefore, the check valve of the present invention is suitably used, for example, in the field of medical devices and the like, for example, at the tip of a syringe, a co-infusion port of an infusion circuit, and the like.
上記本発明に係る逆止弁の好適態様としては、  As a preferred embodiment of the check valve according to the present invention,
(I) 前記弁体と当接する弁座は注入液流通孔を備えており、  (I) a valve seat that is in contact with the valve body has an infusate flow hole,
当該注入液流通孔は、 前記流体圧を受けていないときに弁体によって閉鎖され、 かつ、 前記流体圧を受けているときに開放されて、 弁体と弁座との間に形成され る空隙部への流路となるものであって、 The infusion liquid flow hole is closed by the valve body when not receiving the fluid pressure, and is opened when receiving the fluid pressure to form a gap formed between the valve body and the valve seat. Part to the part,
前記弁体は、 当該弁体の下流側に当接させた係止部によって、 筒体の下流側への 移動が規制されていることを特徴とするもの (第 1の好適態様) と、 The valve body is characterized in that the movement of the cylinder body to the downstream side is restricted by a locking portion abutting on the downstream side of the valve body (first preferred embodiment);
(II) 前記弁体は筒体内壁に摺接して配置されており、  (II) the valve element is disposed in sliding contact with the inner wall of the cylinder,
前記筒体は、 その内壁に、 筒体の軸方向に伸びた凹欠部を 1ケ所または複数ケ所 備えており、 The cylindrical body has, on its inner wall, one or more concave notches extending in the axial direction of the cylindrical body,
当該凹欠部は、 筒体下流側で筒体内部に露出しており、 かつ、 筒体上流側では、 前記流体圧を受けていないときに弁体によって閉鎖され、 前記流体圧を受けてい るときに筒体内部に露出し、 弁体と筒体内壁との間に空隙部を形成して注入液の 流路となるものであって、 The concave portion is exposed to the inside of the tubular body on the downstream side of the tubular body, and is closed by the valve body when not receiving the fluid pressure on the upstream side of the tubular body, and receives the fluid pressure. Sometimes it is exposed inside the cylinder, forms a gap between the valve body and the inner wall of the cylinder, and becomes a flow path for the infusate.
前記弁体は、 当該弁体の下流側に当接させた係止部によって、 筒体の下流側への 移動が規制されていることを特徴とするもの (第 2の好適態様) と、 The valve body is characterized in that the movement of the cylinder body to the downstream side is restricted by a locking portion abutting on the downstream side of the valve body (second preferred embodiment).
が挙げられる。 Is mentioned.
上記第 1の好適態様に係る逆止弁において、 弁体は、 筒体上流側で弁座に当接 し、 筒体下流側で係止部に当接しており、 筒体上流側からの流体圧によって圧縮 変形するものの、 筒体自体が下流側へ移動することなく、 前記弁座と係止部との 間に保持されている。 In the check valve according to the first preferred embodiment, the valve body is in contact with the valve seat on the upstream side of the cylinder, and is in contact with the locking portion on the downstream side of the cylinder, and the fluid from the upstream side of the cylinder is Compressed by pressure Although deformed, the tubular body itself is held between the valve seat and the locking portion without moving downstream.
上記第 1の好適態様における弁体に前記流体圧をかけると、 弁体と弁座との間 に空隙部が形成され、弁座に備えられた注入液流通孔と前記空隙部とを通過して、 筒体の下流側に注入液が排出される。 一方、 前記流体圧の負荷を止めると、 弁体 が元の形状に戻って前記空隙部が消滅するとともに、 注入液流通孔が弁体によつ て閉鎖される。  When the fluid pressure is applied to the valve body in the first preferred embodiment, a gap is formed between the valve body and the valve seat, and the gap passes through the infusate flow hole provided in the valve seat and the gap. Then, the injection liquid is discharged to the downstream side of the cylinder. On the other hand, when the load of the fluid pressure is stopped, the valve body returns to the original shape, the gap disappears, and the injection liquid flow hole is closed by the valve body.
この際、 弁体が元の形状に戻ろうとする動作の方向 (すなわち、 弁体にかかる 流体圧と同軸上にあって、 流体圧とは逆向きの方向) は注入液等が空隙部に流入 する方向と交差していることから、 上記第 1の好適態様によれば、 流体が逆流し ようとする現象を極めて高度に抑制することができる。  In this case, the direction of the movement of the valve body to return to the original shape (that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure) is such that the infused liquid flows into the gap. Therefore, according to the first preferred embodiment, the phenomenon in which the fluid tends to flow backward can be suppressed to a very high degree.
上記第 2の好適態様において、 弁体は筒体内壁に摺接して配置されて、 当該弁 体の下流側で係止部に当接しており、 筒体上流側からの流体圧によって圧縮変形 するものの、 筒体自体が下流側へ移動することなく、 筒体内に保持されている。 上記第 2の好適態様における弁体に前記流体圧をかけると、 筒体下流側におい て筒体内壁に設けられた凹欠部が筒体内部に露出し、 弁体と筒体内壁との間に空 隙部が形成される。 その結果、 筒体内の注入液は、 前記凹欠部を通過して下流側 に注入液が排出される。 一方、 前記流体圧の負荷を止めると、 弁体が元の形状に 戻って、 筒体下流側で凹欠部が閉鎖されるとともに、 前記空隙部が消滅する。 この際、 弁体が元の形状に戻ろうとする動作の方向 (すなわち、 弁体にかかる 流体圧と同軸上にあって、 流体圧とは逆向きの方向) は注入液等が空隙部に流入 する方向と交差していることから、 上記第 1の好適態様と同じく、 上記第 2の好 適態様においても、 流体が逆流しょうとする現象を極めて高度に抑制することが できる。  In the second preferred embodiment, the valve element is disposed in sliding contact with the inner wall of the cylinder, abuts on the locking portion on the downstream side of the valve element, and is compressed and deformed by fluid pressure from the upstream side of the cylinder. However, the cylinder itself is held in the cylinder without moving downstream. When the fluid pressure is applied to the valve element in the second preferred embodiment, a concave notch provided in the inner wall of the cylinder at the downstream side of the cylinder is exposed to the inside of the cylinder, and a gap between the valve element and the inner wall of the cylinder is formed. A void is formed in the gap. As a result, the infusate in the cylinder passes through the concave portion and is discharged downstream. On the other hand, when the load of the fluid pressure is stopped, the valve body returns to the original shape, the concave notch portion is closed on the downstream side of the cylindrical body, and the gap disappears. In this case, the direction of the movement of the valve body to return to the original shape (that is, the direction coaxial with the fluid pressure applied to the valve body and opposite to the fluid pressure) is such that the infused liquid flows into the gap. Since it intersects with the direction in which the fluid flows, in the second preferred embodiment as well as in the first preferred embodiment, the phenomenon in which the fluid tends to flow backward can be suppressed to a very high degree.
本発明の注射器は、 上記本発明に係る逆止弁を備えるとともに、 当該逆止弁の 筒体における下流側開口端に、 注射具を直接もしくは間接的に接続し、 または、 注射具を一体に形成したことを特徴とする。  A syringe according to the present invention includes the check valve according to the present invention, and directly or indirectly connects an injector to a downstream open end of the cylinder of the check valve, or integrally integrates the injector. It is characterized by having been formed.
すなわち、 上記本発明の注射器は、 本発明の逆止弁における筒体の下流側開口 端に直接、 もしくは必要に応じて中空状のアダプタ等を介して、 注射針や注入口 等の注射具を接続したもの、 または、 本発明に係る逆止弁の筒体における下流側 開口端に、 直接にもしくは必要に応じて中空状のアダプタ等を介して、 前記注射 具を一体に形成したもの、 である。 That is, the above-mentioned syringe of the present invention comprises a syringe needle or an injection port directly at the downstream open end of the cylindrical body in the check valve of the present invention, or through a hollow adapter or the like as necessary. Or the like, or integrally with the injection device directly or via a hollow adapter or the like as needed at the downstream open end of the cylinder of the check valve according to the present invention. What is formed.
上記本発明の注射器によれば、 前述の本発明に係る逆止弁を備えていることか ら、 使用時に注入液等の逆流や気泡の混入等が生じるおそれがない。 それゆえ、 前述の空気閉栓症等の問題を招くおそれのない安全な注射器として、 医療分野等 において幅広く使用することができる。  According to the above-mentioned syringe of the present invention, since the check valve according to the present invention is provided, there is no possibility that a backflow of an infusate or the like or mixing of bubbles will occur during use. Therefore, it can be widely used in the medical field and the like as a safe syringe which does not cause the above-mentioned problems such as air embolism.
上記本発明に係る注射器は、 筒体内の弁体より上流において筒体内壁と接続し て、 または、 前記弁座の上流側において注入液流通孔と接続して、 筒体上流側に 尖端を有する中空状の穿刺針を設けたものであってもよい。  The syringe according to the present invention has a point connected to the inner wall of the cylinder upstream of the valve body in the cylinder, or connected to the infusion liquid flow hole upstream of the valve seat, and having a pointed tip on the upstream side of the cylinder. A hollow puncture needle may be provided.
この場合、 例えば、 筒体の上流側開口端に、 注入液を密封充填したシリンジ等 を嵌着して実際の使用に供する際において、 あらかじめ前記シリンジ等を開栓す る必要がなく、 筒体内に設けられた中空状の穿刺針にシリンジ先端部を突き刺す ことによって注入液を流出させることができる。  In this case, for example, when a syringe or the like filled and sealed with an infusate is fitted to the upstream open end of the cylindrical body for use in actual use, it is not necessary to open the syringe or the like in advance, and the cylindrical body is not required. By injecting the tip of the syringe into the hollow puncture needle provided in the above, the infusate can be discharged.
また、 上記本発明に係る注射器は、 筒体の上流側開口端に、 可撓性プラスチッ ク製の注入液容器を直接または間接的に、 かつ、 摺動自在に嵌着したものであつ てもよい。  In addition, the syringe according to the present invention may be one in which a flexible plastic infusion container is directly or indirectly and slidably fitted to the upstream open end of the cylindrical body. Good.
すなわち、 例えば、 可撓性プラスチックからなる、 容器本体を押しつぶして注 入液を排出させるタイプの注入液容器を、 筒体の上流側開口端に直接、 または必 要に応じて中空状のアダプタ等を介して、 かつ、 摺動自在 (スライ ド自在) に嵌 着したものであってもよい。 図面の簡単な説明  That is, for example, an infusion solution container made of a flexible plastic and squeezing the container body to discharge the injection solution is provided directly at the upstream open end of the cylindrical body, or a hollow adapter as necessary. And may be slidably (slidably) fitted through the cover. BRIEF DESCRIPTION OF THE FIGURES
図 1は、 本発明に係る逆止弁の一実施形態を示す部分欠截斜視図であって、 図 l aは筒体上流側 Uから弁体 1 2へ流体圧をかけていない状態を示し、 図 l b は 流体圧 Pをかけた状態を示す。  FIG. 1 is a partially cutaway perspective view showing one embodiment of a check valve according to the present invention, and FIG. 1a shows a state in which fluid pressure is not applied to the valve body 12 from a cylinder upstream side U, Figure lb shows the condition with fluid pressure P applied.
図 2は、 図 l a に示す逆止弁 1 0の横断面図であって、 図 2 a は A— A矢視断 面図、 図 2 b は B— B矢視断面図である。  FIG. 2 is a cross-sectional view of the check valve 10 shown in FIG. La, wherein FIG. 2a is a cross-sectional view taken along the line AA, and FIG. 2b is a cross-sectional view taken along the line BB.
図 3は、 図 l a , 図 l b に示す逆止弁 1 0の縦断面図であって、 図 3 a は筒体 上流側 Uから弁体 12へ流体圧をかけていない状態を示し、 図 3b は流体圧 Pを かけた状態を示す。 FIG. 3 is a longitudinal sectional view of the check valve 10 shown in FIGS. La and lb, and FIG. Fig. 3b shows a state in which fluid pressure is not applied to the valve body 12 from the upstream side U, and Fig. 3b shows a state in which fluid pressure P is applied.
図 4は、 本発明に係る逆止弁の他の実施形態を示す部分欠截斜視図であって、 図 4a は筒体上流側 Uから弁体 22へ流体圧をかけていない状態を示し、 図 4b は流体圧 Pをかけた状態を示す。  FIG. 4 is a partially cutaway perspective view showing another embodiment of the check valve according to the present invention, and FIG. 4a shows a state in which fluid pressure is not applied from the upstream side U of the cylindrical body to the valve body 22, FIG. 4b shows a state where the fluid pressure P is applied.
図 5は、 図 4a に示す逆止弁 20の横断面図であって、 図 4aの A— A矢視断 面図である。  FIG. 5 is a cross-sectional view of the check valve 20 shown in FIG. 4a, and is a cross-sectional view taken along line AA of FIG. 4a.
図 6は、 図 4a , 図 4b に示す逆止弁 20の縦断面図であって、 図 6a は筒体 上流側 Uから弁体 22へ流体圧をかけていない状態を示し、 図 6b は流体圧 Pを かけた状態を示す。  Fig. 6 is a longitudinal sectional view of the check valve 20 shown in Figs. 4a and 4b.Fig. 6a shows a state in which fluid pressure is not applied from the upstream side U of the cylinder to the valve body 22, and Fig. Shows the state where pressure P is applied.
図 7は、 本発明の逆止弁を備えた注射器の一実施形態を示す平面図である。 図 8は、 本発明の逆止弁を備えた注射器の他の実施形態を示す平面図である。 図 9は、 従来の逆止弁の一例を示す縦断面図である。  FIG. 7 is a plan view showing one embodiment of a syringe provided with a check valve of the present invention. FIG. 8 is a plan view showing another embodiment of the syringe provided with the check valve of the present invention. FIG. 9 is a longitudinal sectional view showing an example of a conventional check valve.
図 10は、 従来の逆止弁の一例を示す縦断面図である。  FIG. 10 is a longitudinal sectional view showing an example of a conventional check valve.
図 1 1は、 従来の逆止弁の一例を示す縦断面図である。  FIG. 11 is a longitudinal sectional view showing an example of a conventional check valve.
図 12は、 従来の逆止弁の一例を示す縦断面図である。  FIG. 12 is a longitudinal sectional view showing an example of a conventional check valve.
符号の説明  Explanation of reference numerals
10, 20 逆止弁  10, 20 Check valve
1 1, 2 1 筒体  1 1, 2 1 cylinder
1 1 L, 2 1 L 下流側開口端  1 1 L, 2 1 L Downstream open end
1 1U, 2 1 U 上流側開口端  1 1U, 2 1 U Upstream open end
12, 22 弁体  12, 22 Valve
13 弁座  13 Valve seat
14, 24 空隙部  14, 24 void
15 注入液流通孔  15 Injection fluid flow hole
16, 26 係止部  16, 26 Locking part
23 筒体内壁  23 Cylinder inner wall
25 凹欠部  25 recess
30 可撓性プラスチック製の注入液容器 (注射器) 4 1 注射具 30 Flexible plastic infusion container (syringe) 4 1 syringe
6 1 穿刺針  6 1 Puncture needle
6 2 尖端  6 2 Point
D 注入液  D Injection
L 筒体下流側  L Downstream of cylinder
P 流体圧 (流体圧がかかる方向)  P Fluid pressure (direction in which fluid pressure is applied)
U 筒体上流側  U Upstream side of cylinder
X 筒体の軸方向  X Axial direction of cylinder
y 注入液の流入方向  y Inflow direction
発明を実施するための最良の形態 BEST MODE FOR CARRYING OUT THE INVENTION
以下、 本発明の逆止弁および注射器について詳細に説明する。  Hereinafter, the check valve and the syringe of the present invention will be described in detail.
〔逆止弁〕  〔Check valve〕
本発明の逆止弁は、 前述のように、 (a) 筒体と、 (b) 当該筒体の内部に配置され て注入液の流通を閉鎖し、 かつ、 筒体上流側から流体圧を受けると容易に圧縮変 形して、 弁座または筒体内壁との間に空隙部を形成することを特徴とする、 弾性 体からなる弁体と、 を備えたものである。また、かかる逆止弁において、弁体と、 弁座または筒体内壁とは、 弁体に流体圧がかかる方向と、 弁体が圧縮変形した際 に、 前記空隙部に注入液を流入させる方向と、 が互いに交差するように配置され ている。  As described above, the check valve of the present invention comprises: (a) a cylindrical body; and (b) a flow path that is disposed inside the cylindrical body to block the flow of the infusate, and to reduce fluid pressure from the upstream side of the cylindrical body. And a valve body made of an elastic body, wherein the valve body is easily deformed by compression upon receipt of the valve body to form a gap between the valve body and the inner wall of the cylinder. Further, in such a check valve, the valve body, the valve seat or the inner wall of the cylinder are configured such that a direction in which fluid pressure is applied to the valve body, and a direction in which the injection liquid flows into the gap when the valve body is compressed and deformed. And are arranged to intersect each other.
(第 1の好適態様)  (First preferred embodiment)
図 1〜図 3に示す実施形態は、 前記第 1の好適態様に係る一実施例に相当する ものである。  The embodiment shown in FIGS. 1 to 3 corresponds to an example according to the first preferred embodiment.
図 1は、 本発明に係る逆止弁の一実施形態を示す部分欠截斜視図であって、 同 図 a は筒体上流側 Uから弁体 1 2へ流体圧をかけていない状態を示し、同図 b は 流体圧 Pをかけた状態を示す。  FIG. 1 is a partially cutaway perspective view showing an embodiment of a check valve according to the present invention, and FIG. 1a shows a state in which fluid pressure is not applied to a valve body 12 from a cylinder upstream side U. Fig. B shows a state in which the fluid pressure P is applied.
図 2は、 図 l a に示す逆止弁 1 0の横断面図であって、 同図 a は A— A矢視断 面図、 同図 b は B— B矢視断面図である。 図 3は、 図 l a , 図 l b に示す逆止弁 1 0の縦断面図であって、 同図 a は筒体 上流側 Uから弁体 1 2へ流体圧をかけていない状態 (すなわち、 図 1 aの縦断面 図) を示し、 同図 b は流体圧 Pをかけた状態 (すなわち、 図 l b の縦断面図) を 示す。 なお、 図 3の各縦断面図は、 図 2 a 中に示す C— C線での断面図である。 図 1〜図 3に示す逆止弁 1 0は、 例えば図 1 aおよび図 3 a に示すように、 注 入液 D (図 l aでは省略) の流路である筒体 1 1の内部に、 弁座 1 3に当接して 配置された、 弾性体からなる弁体 1 2を設けたものである。 この弁体 1 2は、 筒 体下流側 Lにて弁体 1 2に当接させた係止部 1 6によって、 筒体下流側 L (注入 液 Dが流れ出ていく側) への移動が規制されている。 FIG. 2 is a cross-sectional view of the check valve 10 shown in FIG. La, wherein FIG. 2A is a cross-sectional view taken along the line AA, and FIG. 2B is a cross-sectional view taken along the line BB. FIG. 3 is a longitudinal sectional view of the check valve 10 shown in FIGS. La and lb. FIG. 3a shows a state in which fluid pressure is not applied from the upstream side U of the cylinder to the valve body 12 (that is, FIG. 1a), and FIG. B shows a state in which the fluid pressure P is applied (that is, a vertical sectional view of FIG. Lb). Each vertical cross-sectional view in FIG. 3 is a cross-sectional view taken along line CC in FIG. 2A. The check valve 10 shown in FIG. 1 to FIG. 3 is provided inside a cylindrical body 11 which is a flow path of the injection liquid D (omitted in FIG. La), for example, as shown in FIG. 1 a and FIG. This is provided with a valve body 12 made of an elastic body and arranged in contact with the valve seat 13. The movement of the valve body 12 to the downstream side L (the side on which the infusate D flows out) is restricted by the locking portion 16 abutted on the valve body 12 at the downstream side L of the cylinder body. Have been.
弁体 1 2は、 筒体上流側 Uから流体圧 Pをかけることによって、 具体的には、 図 7に示すような可撓性プラスチックからなる注入液容器 (注射器) 3 0を筒体 1 1の上流側開口端 1 1 Uに接続し、 容器本体 3 1を押し潰すことによって流体 圧 Pをかけたり、 あるいは、 図 8に示すような注射器用の注入液容器(シリンジ) 5 0を上流側開口端 1 1 Uに接続し、 ビストン 5 1を用いて流体圧 Pをかけたり することによって、 容易に圧縮変形して、 弁座 1 3との間に空隙部 1 4を形成す 弁体 1 2は、 圧縮変形によって、 図 l b および図 3 b に示す状態となる。 すな わち、 筒体上流側 Uからの流体圧 Pの負荷に伴う弁体 1 2の圧縮変形によって、 弁体 1 2と弁座 1 3との間に空隙部 1 4が形成され、 注入液流通孔 1 5と空隙部 1 4とを通じて注入液 Dの排出が可能となる。 一方、 弁体 1 2への流体圧 Pの負 荷を止めると、 弁体 1 2は元の状態(すなわち、 図 l aおよび図 3 a に示す状態) に戻って、 空隙部 1 4が消滅するとともに、 注入液流通孔 1 5が弁体 1 2によつ て閉鎖される。  By applying fluid pressure P from the upstream side U of the cylinder 12, specifically, the injection liquid container (syringe) 30 made of a flexible plastic as shown in FIG. To the upstream open end 1 1 U and apply the fluid pressure P by crushing the container body 31, or the injectable liquid container (syringe) 50 for a syringe as shown in FIG. By connecting to the open end 11 U and applying fluid pressure P using Biston 51, it is easily compressed and deformed to form a void 14 between the valve seat 13 and the valve body 1 Figure 2 shows the state shown in Figure lb and Figure 3b due to compressive deformation. That is, due to the compression deformation of the valve body 12 due to the load of the fluid pressure P from the upstream side U of the cylindrical body, a void portion 14 is formed between the valve body 12 and the valve seat 13, and injection is performed. The injection liquid D can be discharged through the liquid flow holes 15 and the voids 14. On the other hand, when the load of the fluid pressure P on the valve body 12 is stopped, the valve body 12 returns to the original state (ie, the state shown in Fig. La and Fig. 3a), and the void part 14 disappears. At the same time, the injection liquid flow hole 15 is closed by the valve body 12.
弁体 1 2にかかる流体圧 Pの方向は、 弁体 1 2が圧縮変形する際の動作の方向 に一致し、かつ弁体 1 2が復元する際の動作の方向と同軸(軸方向 X )上にある。 これに対し、 弁体 1 2の圧縮変形によって生じた空隙部 1 4に注入液 Dが流入す る方向 y (図 3 b 参照) は、 前述の弁体 1 2に流体圧 Pがかかる方向と同軸上に はなく、 互いに交差 (好ましくは、 直交) している。  The direction of the fluid pressure P applied to the valve body 12 coincides with the direction of operation when the valve body 12 is compressed and deformed, and is coaxial with the direction of operation when the valve body 12 is restored (axial direction X). It's above. On the other hand, the direction y (see FIG. 3 b) in which the injection liquid D flows into the void portion 14 generated by the compression deformation of the valve body 12 is the same as the direction in which the fluid pressure P is applied to the valve body 12 described above. They are not coaxial but intersect each other (preferably orthogonal).
このため、 弁体が元の形状 (位置) に戻る復元動作に伴って注入液等の流体ま でもが上流側に逆流するといつた、 従来の逆止弁において顕著な問題は高度に抑 制される。 また、 たとえ注入液 Dの逆流が生じたとしても、 その量は極めて微量 にしか過ぎない。 すなわち、 図 1〜図 3に示す逆止弁 1 0によれば、 弁体 1 2の 開閉に伴う逆流現象を極めて高度に抑制することができる。 For this reason, the valve element returns to its original shape (position). However, the problem that is remarkable in the conventional check valve, when the gas flows backward to the upstream side, is highly suppressed. Even if the backflow of the injection solution D occurs, the amount is only extremely small. That is, according to the check valve 10 shown in FIGS. 1 to 3, the backflow phenomenon caused by the opening and closing of the valve body 12 can be extremely suppressed.
図 1〜図 3に示す逆止弁 1 0では、 弁座 1 3の上流側において、 注入液流通孔 1 5と連通して、 筒体上流側 Uに尖端 1 7を有する中空状の穿刺針 1 8が設けら れている。  In the check valve 10 shown in FIGS. 1 to 3, a hollow puncture needle having a pointed end 17 at the upstream side U of the cylindrical body is communicated with the injection liquid flow hole 15 on the upstream side of the valve seat 13. 18 are provided.
かかる穿刺針 1 8を有することにより、 筒体 1 1の上流側開口端 1 1 Uから、 例えば注入液を密封充填した注射器 (注入液容器) 3 0を嵌挿することにより、 注入液が密封充填された容器の先端部を実際の使用に供する直前の段階で開封 By having such a puncture needle 18, for example, a syringe (infusion solution container) 30 that is sealed and filled with an infusion solution is inserted from the upstream open end 11 U of the cylindrical body 11 to seal the infusion solution. Open the end of the filled container just before using it for actual use
(開栓)することができる (図 7参照)。 それゆえ、 注入液中への気泡や雑菌の混 入を抑制することができ、 さらに、 逆止弁使用時の利便性をも向上させることが できる。 (Open) (see Figure 7). Therefore, the incorporation of air bubbles and various bacteria into the infusion solution can be suppressed, and the convenience when using the check valve can be improved.
上記第 1の好適態様において、 係止部 1 6は、 図 1に示すようなリブ状のもの に限定されるものではなく、 例えば筒体 1 1の内表面において、 弁体 1 2の筒体 下流側 Lに当接されるようにして設けた突起状のもの (具体的には、 図 4に示す 係止部 2 6のようなもの) であってもよい。 また、 弁体 1 2の筒体下流側 Lに当 接されるようにして設けた網状のものであってもよい。  In the first preferred embodiment, the locking portion 16 is not limited to a rib-shaped member as shown in FIG. 1. For example, on the inner surface of the cylindrical body 11, the cylindrical body of the valve body 12 is formed. It may be a protruding shape provided to be brought into contact with the downstream side L (specifically, a locking portion 26 shown in FIG. 4). Further, it may be a net-shaped member provided so as to be in contact with the downstream side L of the valve body 12.
(第 2の好適態様)  (Second preferred embodiment)
図 4〜図 6に示す実施形態は、 前記第 2の好適態様に係る一実施例に相当する ものである。  The embodiment shown in FIGS. 4 to 6 corresponds to an example according to the second preferred embodiment.
図 4は、 本発明に係る逆止弁の他の実施形態を示す部分欠截斜視図であって、 同図 a は筒体上流側 Uから弁体 2 2へ流体圧をかけていない状態を示し、 同図 b は流体圧 Pをかけた状態を示す。  FIG. 4 is a partially cutaway perspective view showing another embodiment of the check valve according to the present invention. FIG. 4A shows a state in which fluid pressure is not applied to the valve body 22 from the upstream side U of the cylindrical body. Fig. B shows a state where the fluid pressure P is applied.
図 5は、 逆止弁 2 0の横断面図であって、 図 4 a の A— A矢視断面図である。 図 6は、 図 4 a , 図 4 b に示す逆止弁 2 0の縦断面図であって、 同図 a は筒体 上流側 Uから弁体 2 2へ流体圧 Pをかけていない状態 (すなわち、 図 4 a の縦断 面図) を示し、 同図 b は流体圧 Pをかけた状態 (すなわち、 図 4 b の縦断面図) を示す。 なお、 図 6の各縦断面図は、 図 5中に示す B— B線での断面図である。 図 4〜図 6に示す逆止弁 2 0は、 例えば図 4 a および図 6 a に示すように、 注 入液 D (図 4 aでは省略) の流路である筒体 2 1の内部に、 筒体内壁 2 3に摺接 して配置された、弾性体からなる弁体 2 2を設けたものである。この弁体 2 2は、 筒体下流側 Lにて弁体 2 2に当接させた係止部 (突起) 2 6によって、 筒体下流 側 L (注入液 Dが流れ出て行く側) への移動が規制されている。 FIG. 5 is a cross-sectional view of the check valve 20 and is a cross-sectional view taken along the line AA of FIG. 4A. Fig. 6 is a longitudinal sectional view of the check valve 20 shown in Figs. 4a and 4b. Fig. 6a shows a state in which fluid pressure P is not applied from the upstream side U of the cylinder to the valve body 22 ( That is, FIG. 4a shows a vertical cross-sectional view), and FIG. B shows a state in which a fluid pressure P is applied (ie, a vertical cross-sectional view of FIG. 6 are cross-sectional views taken along line BB shown in FIG. The check valve 20 shown in FIGS. 4 to 6 is, for example, as shown in FIGS. 4A and 6A, provided inside the cylindrical body 21 which is a flow path of the injection liquid D (omitted in FIG. 4A). In addition, a valve body 22 made of an elastic body and provided in sliding contact with the inner wall 23 of the cylinder is provided. The valve body 22 is connected to the downstream side L (the side on which the infused liquid D flows out) of the valve body 22 by a locking portion (projection) 26 abutted against the valve body 22 at the downstream side L of the cylinder body. Movement is regulated.
弁体 2 2は、 筒体上流側 Uから流体圧 Pをかけることによって、 具体的には、 図 7に示すような可撓性プラスチックからなる注入液容器 (注射器) 3 0を筒体 2 1の上流側開口端 2 1 Uに接続し、 容器本体 3 1を押し潰すことによって流体 圧 Pをかけたり、 あるいは、 図 8に示すような注射器用の注入液容器(シリンジ) 5 0を上流側開口端 2 1 Uに接続し、 ピストン 5 1を用いて流体圧 Pをかけたり することによって、 容易に圧縮変形して、 筒体内壁 2 3との間に空隙部 2 4を形 成する。  The valve body 22 is formed by applying a fluid pressure P from the upstream side U of the cylindrical body, specifically, by injecting an infusate container (syringe) 30 made of a flexible plastic as shown in FIG. To the upstream open end 21 U of the container and apply the fluid pressure P by crushing the container body 31, or the injection liquid container (syringe) 50 for a syringe as shown in FIG. By being connected to the open end 21 U and applying a fluid pressure P using the piston 51, it is easily compressed and deformed to form a void 24 between the inner wall 23 of the cylinder.
弁体 2 2は、 圧縮変形によって図 4 b および図 6 b に示す状態となる。 すなわ ち、 筒体上流側 Uからの流体圧 Pの負荷に伴う弁体 2 2の圧縮変形によって、 凹 欠部 2 5の始端 2 5 U (図 4 aおよび図 6 a参照) が筒体の内表面に露出し、 弁 体 2 2と筒体内壁 2 3 (特に、 凹欠部 2 5の内表面) との間に空隙部 2 4が形成 され、 この空隙部 2 4を通じて注入液 Dの排出が可能となる。 一方、 弁体 2 2へ の流体圧 Pの負荷を止めると、 弁体 2 2は元の状態 (すなわち、 図 4 aおよび図 6 a に示す状態) に戻って、 凹欠部 2 5の始端 2 5 Uが閉鎖されるとともに、 空 隙部 2 4が消滅する。  The valve element 22 is brought into the state shown in FIGS. 4B and 6B by compression deformation. That is, due to the compressive deformation of the valve body 22 caused by the load of the fluid pressure P from the upstream side U of the cylindrical body, the starting end 25 U of the concave portion 25 (see FIG. 4A and FIG. 6A) becomes cylindrical. A cavity 24 is formed between the valve body 22 and the inner wall 23 of the cylinder (particularly, the inner surface of the recessed portion 25), and the injection solution D is formed through the cavity 24. Can be discharged. On the other hand, when the application of the fluid pressure P to the valve body 22 is stopped, the valve body 22 returns to the original state (that is, the state shown in FIGS. 4A and 6A), and the starting end of the concave notch 25 While 25 U is closed, the void 24 disappears.
弁体 2 2にかかる流体圧: Pの方向は、 弁体 2 2が圧縮変形する際の動作の方向 に一致し、かつ弁体 2 2が復元する際の動作の方向と同軸(軸方向 X )上にある。 これに対し、 凹欠部 2 5の始端 2 5 Uが筒体の内部に露出することによって生じ た空隙部 2 4に注入液 Dが流入する方向 y (図 4 b および図 6 b 参照) は、 前述 の弁体 2 2に流体圧 Pがかかる方向と同軸上にはなく、互いに交差(好ましくは、 直交) している。  Fluid pressure applied to the valve element 22: The direction of P coincides with the direction of operation when the valve element 22 is compressed and deformed, and is coaxial with the direction of operation when the valve element 22 is restored (axial direction X). )It's above. On the other hand, the direction y (see FIGS. 4 b and 6 b) in which the infusate D flows into the gap 24 formed by exposing the starting end 25 U of the concave notch 25 to the inside of the cylinder. However, the valve body 22 is not coaxial with the direction in which the fluid pressure P is applied to the valve body 22 and intersects (preferably, orthogonally) with each other.
このため、 弁体が元の形状 (位置) に戻る復元動作に伴って注入液等の流体ま でもが上流側に逆流するといつた、 従来の逆止弁において顕著な問題が高度に抑 制される。 また、 たとえ注入液 Dの逆流が生じたとしても、 その量は極めて微量 にしか過ぎない。 すなわち、 図 4〜図 6に示す逆止弁 2 0によれば、 弁体 2 2の 開閉に伴う逆流現象を極めて高度に抑制することができる。 For this reason, remarkable problems in the conventional check valve, in which even the fluid such as the infusate flows back to the upstream side with the restoration operation of the valve body returning to the original shape (position), are highly suppressed. You. Also, even if the backflow of the injection solution D occurs, the amount is extremely small. It's just that. That is, according to the check valve 20 shown in FIGS. 4 to 6, the backflow phenomenon accompanying the opening and closing of the valve body 22 can be suppressed to a very high degree.
上記第 2の好適態様においては、 上流側に係止部 2 6 Uを設けてもよい。 この 場合、 弁体 2 2の筒体上流側 Uへの移動を規制することができる。  In the second preferred embodiment, a locking portion 26U may be provided on the upstream side. In this case, the movement of the valve body 22 to the upstream side U of the cylindrical body can be restricted.
上記第 2の好適態様において、 係止部 2 6, 2 6 Uは、 図 4および図 6に示す ような突起状のものに限定されるものではなく、 例えば筒体 2 1の軸方向 Xに伸 びるリブ状のもの (具体的には、 図 1に示す係止部 1 6のようなもの) であって もよい。 この場合、 筒体 2 1との一体成形により係止部を形成できるなど、 その 形成工程が容易になるとともに、 筒体 2 1の強度を補強する利点をも得ることが できる。 また、 係止部 2 6, 2 6 Uは、 弁体 1 2の筒体上流側 Uまたは筒体下流 側 Lに当接されるようにして設けた網状のものであってもよい。  In the second preferred embodiment, the locking portions 26 and 26 U are not limited to protrusions as shown in FIGS. 4 and 6, for example, in the axial direction X of the cylindrical body 21. It may be an extending rib-shaped member (specifically, a locking member 16 shown in FIG. 1). In this case, the formation process can be simplified, for example, the locking portion can be formed by integral molding with the cylinder 21, and the advantage of reinforcing the strength of the cylinder 21 can be obtained. Further, the locking portions 26 and 26 U may be a net-like member provided so as to be in contact with the upstream side U or the downstream side L of the valve body 12.
(弾性体)  (Elastic body)
本発明の逆止弁において弁体として用いられる弾性体は、 例えば注射器のピス トンを押圧することなどによって生じる注入液の流体圧によって容易に変形可能 な程度に柔らかく、 かつ、 流体圧を負荷しない状態ではその形状が維持されるも の、 例えばゲルとしての性状を示すものであるほかは、 特に限定されるものでは ない。  The elastic body used as the valve body in the check valve of the present invention is soft enough to be easily deformable by the fluid pressure of the infusate generated by, for example, pressing the piston of the syringe, and does not apply fluid pressure. It is not particularly limited except that it retains its shape in the state, for example, it shows properties as a gel.
かかる弾性体としては、 具体的には、 天然ゴム、 シリコーンゴム、 イソプレン ゴム、 ブタジエンゴム、 フッ素ゴム等のゴム ; ポリエチレン、 ポリプロピレン等 のブラスチック ;各種熱可塑性エラストマ一、 といった弾性部材のうち、 硬度が 十分に低く、 ゲルとしての性状を十分に示すものが挙げられる。 とりわけ、 熱可 塑性エラストマ一が好ましく用いられる。  Specific examples of such an elastic body include rubbers such as natural rubber, silicone rubber, isoprene rubber, butadiene rubber, and fluororubber; plastics such as polyethylene and polypropylene; various thermoplastic elastomers; Is sufficiently low, and shows properties sufficiently as a gel. In particular, a thermoplastic elastomer is preferably used.
上記熱可塑性エラストマ一としては、 さらに詳しくは、 例えばスチレンーェチ レン/プチレン一スチレンプロヅク共重合体(S E B S )、 スチレン一ブタジエン 一スチレンプロック共重合体(S B S )、 スチレン一イソプレン一スチレンブロッ ク共重合体(S I S )、 マレイン酸変性等の変性 S E B S、 スチレン一エチレン/ プロピレン一スチレンプロック共重合体(S E P S )、 スチレン一エチレン/プチ レンプロック共重合体(S E B )、スチレン一ェチレン /プロピレンプロック共重 合体 (S E P ) 等のスチレン系エラストマ一;エチレン一プロピレンプロック共 重合体等のォレフィン系エラストマ一;ポリウレタン系エラストマ一等、 および これらの混合物が挙げられる。 More specifically, the thermoplastic elastomer is, for example, styrene-ethylene / butylene-styrene-block copolymer (SEBS), styrene-butadiene-styrene block copolymer (SBS), styrene-isoprene-styrene block copolymer. Copolymer (SIS), modified SEBS such as maleic acid modification, styrene-ethylene / propylene-styrene block copolymer (SEPS), styrene-ethylene / butylene block copolymer (SEB), styrene-ethylene / propylene block copolymer Styrene-based elastomers such as (SEP); ethylene and propylene block Olefin elastomers such as polymers; polyurethane elastomers; and mixtures thereof.
弾性体の大きさは特に限定されるものではないが、 特に上記第 2の好適態様の 場合には、 弾性体の直径は逆止弁を構成する筒体の内径に応じて、 弾性体の長さ は凹欠部の長さ、 位置等に応じて適宜設定すればよい。  Although the size of the elastic body is not particularly limited, particularly in the case of the second preferred embodiment, the diameter of the elastic body is determined by the length of the elastic body according to the inner diameter of the cylinder constituting the check valve. The length may be appropriately set according to the length, position, and the like of the concave portion.
いずれの態様においても、 弾性体 (すなわち、 弁体) が大きすぎると、 弾性体 を圧縮した際に直径方向への膨らみが大きくなりすぎて、 凹欠部を塞いでしまう おそれが生じる。 また、 弾性体が小さすぎると、 充分な圧縮変形が流体の流通の 妨げとなるおそれがある。 このため、 弾性体の大きさは、 圧縮変形の程度をも考 慮して設定する必要がある。  In any of the aspects, if the elastic body (that is, the valve body) is too large, the swelling in the diametrical direction becomes too large when the elastic body is compressed, and there is a possibility that the recessed portion is closed. If the elastic body is too small, sufficient compressive deformation may hinder the flow of the fluid. For this reason, the size of the elastic body must be set in consideration of the degree of compressive deformation.
上記弾性体の、流体圧による変形性を示す指標としては、例えば弾性体の硬さ、 引張応力、 圧縮弾性率等が挙げられる。  As an index indicating the deformability of the elastic body due to fluid pressure, for example, hardness, tensile stress, compression elastic modulus and the like of the elastic body can be mentioned.
本発明に用いられる弾性体の硬さは、 J I S A硬度 〔J I S K 6 3 0 1 - 5 . 2 「スプリング式硬さ試験」 に記載の方法にて測定したスプリング硬さ Η s ( Α形)〕 が 0〜2 0であるのが好ましく、 0 ~ 1 0であるのがより好ましい。 弾性体の硬度が上記範囲を超えると、 弾性体が硬くなりすぎて、 流体圧では十 分に変形しなくなるおそれがある。 一方、 流体圧を負荷しない時にその形状を維 持できる状態とするには、 硬度の下限は上記の値とするのが限度である。  The hardness of the elastic body used in the present invention is JISA hardness [spring hardness に て s (Α type) measured by the method described in “JISK 631-5.2“ Spring hardness test ”). It is preferably from 0 to 20 and more preferably from 0 to 10. If the hardness of the elastic body exceeds the above range, the elastic body may be too hard and may not be sufficiently deformed by the fluid pressure. On the other hand, the lower limit of hardness is limited to the above value in order to maintain the shape when no fluid pressure is applied.
本発明に用いられる弾性体の引張応力は、 1 0 0 %伸び時における引張応力 Μ loo (M P a ) J I S K 6 2 5 1〕 が 0 . 0 5〜 2 . 0 M P aであるのが好 ましく、 0 . 0 5 ~ 0 . 5 M P aであるのがより好ましい。  The elastic material used in the present invention preferably has a tensile stress Μ loo (MPa) JISK 6251] at an elongation of 100% of 0.05 to 2.0 MPa. More preferably, it is in the range of 0.05 to 0.5 MPa.
弾性体の引張応力が上記範囲を超えると、 流体圧で変形しなくなるおそれがあ る。 逆に、 弾性体の引張応力が上記範囲を下回ると、 流体圧を取り除いた後に、 弾性体が十分に復元しなくなるおそれがある。  If the tensile stress of the elastic body exceeds the above range, the elastic body may not be deformed by the fluid pressure. Conversely, if the tensile stress of the elastic body falls below the above range, the elastic body may not be fully restored after the fluid pressure is removed.
なお、 弾性体は、 流体圧の負荷、 除圧を繰り返し行っても破損することがない ように、その圧縮永久歪み率 C S ( % ) 〔J I S K 6 3 0 1 ,測定条件: 7 0 °C x 2 2時間〕 が 3 0以下であるのが好ましい。  In order to prevent the elastic body from being damaged even if the fluid pressure is repeatedly applied and depressurized, its compression set CS (%) [JISK6301, measurement conditions: 70 ° C x 22 hours] is preferably 30 or less.
さらに、 上記弾性体としては、 前述の性質を満たすものであれば、 発泡体 (但 し、 孔が不連続で、 液漏れを生じさせることがないもの) や、 添加物によって前 述の性質を満たすように調整した素材を採用することもできる。 かかる素材の具 体例としては、 市販のシリコーン一ウレタン系ゲルである商品名 「ケミテックゲ ル」 (ケミテック社製)に、汎用の添加剤を適宜添加したものを挙げることができ (筒体) Further, as the above-mentioned elastic body, as long as it satisfies the above-mentioned properties, a foam (however, one having discontinuous pores and not causing liquid leakage) or an additive may be used. It is also possible to adopt a material adjusted to satisfy the above-described properties. An example of such a material is a commercially available silicone-urethane gel (trade name: Chemitech Gel (manufactured by Chemitech)) to which a general-purpose additive is appropriately added (cylindrical body).
本発明の逆止弁における筒体は、 例えば従来の注射器等に用いられる、 ポリエ チレン、 ポリプロピレン、 ポリ 4ーメチルペンテン 〔例えば、 三井化学 (株) の 商品名「T P X」〕等のポリオレフィン;エチレン一テトラシクロドデセン共重合 体〔三井化学 (株) の商品名「アベル」〕等のポリ環状ォレフィン;ァクリロニト リル一ブタジエン一スチレン共重合体(A B S );ポリエチレンナフ夕レート (Ρ Ε Ν )、 ポリエチレンテレフ夕レート (Ρ Ε Τ )、 ポリアリレート等のポリエステ ル;ポリフエ二レンサルフアイ ド (P P S ) 等のベンゼン系重合体などの、 種々 のプラスチックによって形成される。  The cylinder in the check valve of the present invention may be, for example, a polyolefin such as polyethylene, polypropylene, poly-4-methylpentene [for example, trade name “TPX” of Mitsui Chemicals, Inc.] used for conventional syringes and the like; Polycyclic olefins such as cyclododecene copolymer (trade name “Abel” of Mitsui Chemicals, Inc.); acrylonitrile-butadiene-styrene copolymer (ABS); polyethylene naphthylate (Ρ Ε 、), polyethylene tereph It is formed of various plastics, such as polyester such as evening rate (Ρ Ε Τ) and polyarylate; and benzene-based polymer such as polyphenylene sulfide (PPS).
筒体の内表面に設けられる注入液流通路の数や、 長さ、 幅等は特に限定される ものではなく、 注入液等の逆流防止を十分に図ることができる程度に、 かつ、 上 流側から弾性体に流体圧を負荷した状態において、 注入液等をスムーズに排出す ることができるように、 適宜設定される。  The number, length, width, and the like of the injection liquid flow passages provided on the inner surface of the cylindrical body are not particularly limited, and the flow of the injection liquid or the like is sufficiently large to prevent the backflow of the injection liquid and the like. It is set appropriately so that the infused liquid and the like can be smoothly discharged when the fluid pressure is applied to the elastic body from the side.
本発明の逆止弁における筒体は、 例えば、 筒体上流側 Uの開口端 1 1 Uから弁 座 1 3までの部分を射出成形、 押出成形等の方法にて形成し、 この筒体の弁座 1 3上に弁体 1 2を配置した後、 射出成形、 押出成形等の方法にて別途形成された 下流側開口端 1 1 L側の筒体と合わせて、 両方の筒体を熱溶着、 超音波溶着、 嵌 合、組立て等の方法にて固着することによって製造されたり (図 1参照)、 あるい は、 筒体下流側 Lの開口端 2 1 Lから凹欠部 2 5の始端 2 5 Uまでの部分を射出 成形、 押出成形等の方法にて形成し、 この筒体の内部に弁体 2 2を挿入し、 筒体 内壁 2 3に設置された係止部 2 6に弁体 2 2を当接させた後、 射出成形、 押出成 形等の方法にて別途形成された上流側開口端 2 1 U側の筒体と合わせて、 両方の 筒体を熱溶着、 超音波溶着、 嵌合、 組立て等の方法にて固着することによって製 造される (図 4参照)。  The cylinder in the check valve of the present invention is formed by, for example, injection molding, extrusion molding, or the like, from the opening end 11 U of the cylinder upstream side U to the valve seat 13. After arranging the valve body 12 on the valve seat 13, heat both cylinders together with the downstream opening end 11 L side cylinder separately formed by injection molding, extrusion molding, etc. It is manufactured by fixing by welding, ultrasonic welding, fitting, assembling, etc. (see Fig. 1), or it can be formed from the open end 21 L on the downstream side L of the cylindrical body to the concave notch 25 The portion up to the starting end 25 U is formed by injection molding, extrusion molding, or the like, and the valve body 22 is inserted into the inside of this cylindrical body, and the locking portion 26 installed on the inner wall 23 of the cylindrical body is formed. After the valve body 22 is brought into contact, both the cylinders are heat welded together with the upstream open end 21 U side cylinder separately formed by injection molding, extrusion molding, etc. Sonic welding Fitting, it is manufacturing by fixing by a method of assembly or the like (see FIG. 4).
また、 上記の製造方法のほかにも、 筒体全体を一体成形した後で、 弁体を筒体 内に挿入する方法を採用することもできる。 In addition to the above manufacturing method, after the entire cylinder is integrally molded, the valve It is also possible to adopt a method of inserting the inside.
〔注射器〕  〔Syringe〕
本発明の注射器は、 前述のように、 上記本発明の逆止弁を備えるとともに、 当 該逆止弁の筒体における下流側開口端に、 注射具を直接もしくは間接的に接続し たもの、 あるいは、 本発明の逆止弁を備えるとともに、 逆止弁の筒体における下 流側開口端に、 注射具を一体に形成したもの、 である。  As described above, the syringe according to the present invention includes the check valve according to the present invention, and a syringe directly or indirectly connected to a downstream open end of the cylindrical body of the check valve. Alternatively, a check valve of the present invention is provided, and a syringe is integrally formed at a downstream opening end of a cylindrical body of the check valve.
図 7および図 8に示す実施形態は、 上記本発明の逆止弁を備えた注射器に相当 するものである。  The embodiment shown in FIGS. 7 and 8 corresponds to a syringe provided with the above-described check valve of the present invention.
図 7に示す注射器は、 注入液を密封充填した可撓性プラスチック製の注入液容 器 (注射器) 3 0を、 上記本発明の逆止弁 1 0における筒体 1 1の上流側開口端 1 1 Uに直接、 接続したものである。  In the syringe shown in FIG. 7, a flexible plastic infusion container (syringe) 30 sealed and filled with an infusion solution is connected to the upstream opening end 1 of the cylinder 11 in the check valve 10 of the present invention. Directly connected to 1 U.
この注入液容器 (注射器) 3 0は、 容器本体 3 1を押しつぶして、 図 7中に点 線で示す形状となるように変形させることにより、 当該容器本体 3 1中に充填さ れた注入液を排出させるものである。 かかる注入液容器 (注射器) 3 0は、 注入 液を排出させるための部品が少なく、 製造が容易であり、 かつ、 保存時の密封性 が保たれるという利点を有する。  The infusate container (syringe) 30 is formed by crushing the container body 31 and deforming it into the shape shown by the dotted line in FIG. Is to be discharged. Such an infusion solution container (syringe) 30 has advantages in that it has few components for discharging the infusion solution, is easy to manufacture, and maintains hermeticity during storage.
図 7に示す注射器によれば、 注入液容器 (注射器) 3 0より下流に本発明の逆 止弁 1 0が接続されていることから、 注入液が逆流するという問題を高度に抑制 することができる。  According to the syringe shown in FIG. 7, since the check valve 10 of the present invention is connected downstream of the infusion liquid container (syringe) 30, the problem that the infusion liquid flows backward can be highly suppressed. it can.
なお、 図 7に示す注射器において、 注入液容器 (注射器) 3 0は、 例えばァダ プ夕等を介して、 上流側開口端 1 1 Uに間接的に接続したものであってもよく、 あるいは、 上流側開口端 1 1 Uと一体に形成されたものであってもよい。  In the syringe shown in FIG. 7, the infusate container (syringe) 30 may be indirectly connected to the upstream open end 11 U, for example, through an adapter, or However, it may be formed integrally with the upstream opening end 11U.
図 8に示す注射器は、 逆止弁 2 0の筒体 2 1における下流側開口端 2 1 Lに、 注射針 4 0を有する注射具 4 1を直接接続し、 かつ、 上流側開口端 2 1 Uに、 注 入液を密封充填した注入液容器 (シリンジ) 5 0を、 穿刺針 6 1を有するァダプ 夕 6 0を介して、 間接的に接続したものである。  In the syringe shown in FIG. 8, a syringe 41 having a syringe needle 40 is directly connected to a downstream open end 21 L of a cylindrical body 21 of a check valve 20, and an upstream open end 21 is provided. An infusion solution container (syringe) 50 sealed and filled with an injection solution is indirectly connected to U via an adapter 60 having a puncture needle 61.
注射具 4 1は、 例えばアダプタ等を介して、 下流側開口端 2 1 Lに間接的に接 続したものであってもよく、 あるいは、 下流側開口端 2 1 Lと一体に形成された ものであってもよい。 上記注入液容器 (シリンジ) 5 0は、 ピストン 5 1に圧をかけることにより、 当該シリンジ 5 0中に充填された注入液を排出させるものである。 かかる注入液 容器 (シリンジ) 5 0では、 ピストン 5 1への加圧を止めた時に注入液等が逆流 するおそれがあるものの、 図 8に示す注射器によれば、 注入液容器 (シリンジ) 5 0より下流に本発明の逆止弁 2 0が接続されていることから、 注入液が逆流す るという問題を高度に抑制することができる。 The injection device 41 may be indirectly connected to the downstream open end 21 L via an adapter or the like, or may be integrally formed with the downstream open end 21 L. It may be. The injection liquid container (syringe) 50 discharges the injection liquid filled in the syringe 50 by applying pressure to the piston 51. In such an infusate container (syringe) 50, although the infusate and the like may flow backward when pressurization of the piston 51 is stopped, according to the syringe shown in FIG. 8, the infusate container (syringe) 50 Since the check valve 20 of the present invention is connected further downstream, the problem that the infusate flows backward can be highly suppressed.
注入液容器 (シリンジ) 5 0は、 図 8に示すアダプタ 6 0を介さずに、 上流側 開口端 2 1 Uに直接、 接続したものであってもよい。  The infusion solution container (syringe) 50 may be directly connected to the upstream open end 21 U without passing through the adapter 60 shown in FIG.
但し、 図 8に示すアダプタ 6 0の内部には、 筒体上流側 2 1 Uに尖端 6 2を有 する穿刺針 6 1が、 当該アダプタ 6 0の筒体内壁に接続して備えられており、 か かる穿刺針 6 1を用いることによって、 シリンジ 5 0の先端部を実際の使用に供 する直前の段階で開封 (開栓) することができる。 それゆえ、 注入液中への気泡 や雑菌の混入を抑制でき、 使用時の利便性を向上させることもできる。  However, inside the adapter 60 shown in FIG. 8, a puncture needle 61 having a point 62 on the upstream side 21 U of the cylindrical body is provided so as to be connected to the inner wall of the cylindrical body of the adapter 60. By using such a puncture needle 61, the tip of the syringe 50 can be opened (opened) immediately before it is actually used. Therefore, air bubbles and various bacteria can be prevented from being mixed into the infusion solution, and the convenience during use can be improved.
注入液容器 (シリンジ) 5 0は、 さらに、 上流側開口端 2 1 Uと一体に形成さ れたものであってもよい。  The injection liquid container (syringe) 50 may be formed integrally with the upstream open end 21U.
(注入具)  (Injector)
本発明の注射器に用 、られる注入具としては、 中空のものであるほかは特に限 定されるものではなく、 両頭針でも、 一方の端部にのみ先鋭部を有するもののい ずれであってもよい。 また、 金属製の針であってもプラスチック製の針であって もよく、 これらは、 注射器の用途に応じて、 適宜選択できる。 注入針がプラスチ ック製のものである場合には、 注入具を、 本発明の逆止弁における筒体に直接接 続して、 一体成形することが可能となる。  The injecting device used for the syringe of the present invention is not particularly limited except that it is hollow, and may be either a double-ended needle or a device having a sharpened portion only at one end. Good. Further, it may be a metal needle or a plastic needle, and these may be appropriately selected depending on the use of the syringe. When the injection needle is made of plastic, the injection tool can be directly connected to the cylinder of the check valve of the present invention to be integrally formed.
本発明の注射器において、 注入液を収容するシリンジやビストン等は、 従来公 知の注射器と同様なものを用いることができる。  In the syringe of the present invention, the same syringes and bistones as those conventionally known can be used for accommodating the infusion solution.
本発明に係る逆止弁および注射器は、 上記のものに限定されるものではなく、 本発明の目的および作用 ·効果を損なうことのない範囲において、 適宜設計を変 更することができる。  The check valve and the syringe according to the present invention are not limited to those described above, and the design can be appropriately changed within a range that does not impair the object, operation and effect of the present invention.
また、 本発明に係る逆止弁は、 上記例示の医療用注射器に適用されるほか、 流 体の逆流や気泡の混入を防止する必要のある種々の器材に対しても適用すること ができる。 産業上の利用分野 In addition, the check valve according to the present invention is applicable not only to the medical syringe described above, but also to various devices that need to prevent backflow of fluid and mixing of air bubbles. Can be. Industrial applications
前述のように、 本発明の注射器は、 前記逆止弁を備えていることから、 使用時 に注入液等の逆流や気泡の混入等が生じるおそれがない。 それゆえ、 前述の空気 閉栓症等の問題を招くおそれのなレ、安全な注射器として、 医療分野等において幅 広く使用することができる。  As described above, since the syringe of the present invention is provided with the check valve, there is no danger of backflow of the infusate, mixing of air bubbles, etc. during use. Therefore, it can be widely used in the medical field and the like as a safe syringe without causing the aforementioned problems such as air embolism.

Claims

請 求 の 範 囲 The scope of the claims
1 . 少なくとも、 筒体と、 弾性体からなる弁体と、 を備えており、  1. At least a cylindrical body and a valve body made of an elastic body are provided.
前記弁体は、 筒体内部に配置されて注入液の流通を閉鎖し、 かつ、 筒体上流側 から流体圧を受けると容易に圧縮変形して、 弁座または筒体内壁との間に空隙部 を形成するとともに、 当該空隙部を通じて注入液を流通させるものであって、 前記弁体と、 弁座または筒体内壁とは、 弁体に前記流体圧がかかる方向と、 弁 体が圧縮変形した際に、 前記空隙部に注入液を流入させる方向と、 を交差させる ように配置されていることを特徴とする逆止弁。  The valve body is disposed inside the cylinder to close the flow of the infusate, and is easily compressed and deformed when it receives fluid pressure from the upstream side of the cylinder, so that a gap is formed between the valve body and the inner wall of the cylinder. And the valve body, the valve seat or the inner wall of the cylinder, the direction in which the fluid pressure is applied to the valve body, and the valve body is compressed and deformed. A check valve arranged so as to intersect with the direction in which the infusion liquid flows into the gap when the gap is formed.
2 . 前記弁体と当接する弁座は注入液流通孔を備えており、  2. The valve seat that comes into contact with the valve body is provided with an infusate flow hole,
当該注入液流通孔は、前記流体圧を受けていないときに弁体によって閉鎖され、 かつ、 前記流体圧を受けているときに開放されて、 弁体と弁座との間に形成され る空隙部への流路となるものであって、  The infusion liquid flow hole is closed by the valve body when not receiving the fluid pressure, and is opened when receiving the fluid pressure, to form a gap formed between the valve body and the valve seat. Part to the part,
前記弁体は、 当該弁体の下流側に当接させた係止部によって、 筒体下流側への 移動が規制されている請求項 1記載の逆止弁。  2. The check valve according to claim 1, wherein movement of the valve body to a downstream side of the cylindrical body is restricted by a locking portion abutted on a downstream side of the valve body.
3 . 前記弁体は筒体内壁に摺接して配置されており、  3. The valve body is disposed in sliding contact with the inner wall of the cylinder,
前記筒体は、 その内壁に、 筒体の軸方向に伸びた凹欠部を 1ケ所または複数ケ 所備えており、  The cylindrical body has one or more concave notches on its inner wall extending in the axial direction of the cylindrical body,
当該凹欠部は、筒体下流側で筒体内部に露出しており、かつ、筒体上流側では、 前記流体圧を受けていないときに弁体によって閉鎖され、 前記流体圧を受けてい るときに筒体内部に露出し、 弁体と筒体内壁との間に空隙部を形成して注入液の 流路となるものであって、  The concave notch is exposed to the inside of the cylindrical body on the downstream side of the cylindrical body, and is closed by the valve body when not receiving the fluid pressure on the upstream side of the cylindrical body, and receives the fluid pressure. Sometimes it is exposed inside the cylinder, forms a gap between the valve body and the inner wall of the cylinder, and becomes a flow path for the infusate.
前記弁体は、 当該弁体の下流側に当接させた係止部によって、 筒体下流側への 移動が規制されている請求項 1記載の逆止弁。  2. The check valve according to claim 1, wherein the movement of the valve body toward the downstream side of the cylinder is restricted by a locking portion abutting on the downstream side of the valve body.
4 . 前記弁体が熱可塑性エラストマ一より成形されたものである請求項 1記載 の逆止弁。  4. The check valve according to claim 1, wherein the valve body is formed of a thermoplastic elastomer.
5 . 前記弁体の J I S A硬度が 0 ~ 2 0である請求項 4記載の逆止弁。  5. The check valve according to claim 4, wherein the JIS hardness of the valve body is 0 to 20.
6 . 前記弁体の引張応力が 0 . 0 5〜2 . O M P aである請求項 4記載の逆止 弁。  6. The check valve according to claim 4, wherein a tensile stress of the valve body is 0.05 to 2.0MPa.
7 . 前記弁体の圧縮永久歪み率が 3 0以下である請求項 4記載の逆止弁。 7. The check valve according to claim 4, wherein the compression set of the valve body is 30 or less.
8 . 請求項 1〜 7のいずれかに記載の逆止弁を備えるとともに、 8. With the check valve according to any one of claims 1 to 7,
当該逆止弁の筒体における下流側開口端に、 注射具を直接もしくは間接的に接 続し、 または、 注射具を一体に形成したことを特徴とする注射器。  A syringe characterized in that an injection device is connected directly or indirectly to a downstream open end of a cylindrical body of the check valve, or the injection device is integrally formed.
9 . 前記筒体内の弁体より上流において筒体内壁と接続して、 または、 前記弁 座の上流側において注入液流通孔と接続して、 筒体上流側に尖端を有する中空状 の穿刺針を設けた請求項 8記載の注射器。  9. A hollow puncture needle that is connected to the inner wall of the cylinder upstream of the valve body in the cylinder, or connected to the infusion liquid flow hole upstream of the valve seat, and has a pointed tip on the upstream side of the cylinder. 9. The syringe according to claim 8, wherein the syringe is provided.
1 0 . 前記筒体の上流側開口端に、 可撓性プラスチック製の注入液容器を直接 または間接的に、 かつ、 摺動自在に嵌着した請求項 8または 9記載の注射器。  10. The syringe according to claim 8 or 9, wherein a flexible plastic infusion container is directly or indirectly and slidably fitted to the upstream open end of the cylindrical body.
PCT/JP2000/009179 1999-12-28 2000-12-25 Check valve, and syringe using the same WO2001047583A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU24016/01A AU2401601A (en) 1999-12-28 2000-12-25 Check valve, and syringe using the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11/374298 1999-12-28
JP37429899 1999-12-28

Publications (1)

Publication Number Publication Date
WO2001047583A1 true WO2001047583A1 (en) 2001-07-05

Family

ID=18503611

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2000/009179 WO2001047583A1 (en) 1999-12-28 2000-12-25 Check valve, and syringe using the same

Country Status (3)

Country Link
AU (1) AU2401601A (en)
TW (1) TW469138B (en)
WO (1) WO2001047583A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010512206A (en) * 2006-12-13 2010-04-22 アーツナイミッテル・ゲーエムベーハー・アポテーカー・フェッター・ウント・コンパニー・ラフェンスブルク Fitting for syringe or cartridge
JP2010259546A (en) * 2009-04-30 2010-11-18 Yoshino Kogyosho Co Ltd Syringe container
JP2010273921A (en) * 2009-05-29 2010-12-09 Yoshino Kogyosho Co Ltd Syringe container
JP2013538995A (en) * 2010-09-02 2013-10-17 ロベルト・ボッシュ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Fluid flow throttling device and corresponding fluid supply piston pump
JP2016509912A (en) * 2013-03-15 2016-04-04 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Body member and diaphragm material for medical devices
KR20200145164A (en) * 2019-06-21 2020-12-30 한국수력원자력 주식회사 Flow control device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045039U (en) * 1983-09-06 1985-03-29 テルモ株式会社 non-return valve
JPH04137771U (en) * 1991-06-19 1992-12-22 関西日本電気株式会社 Liquid metered dispensing device
US5893842A (en) * 1993-02-05 1999-04-13 Becton, Dickinson And Company Syringe needle isolation device
JPH11159641A (en) * 1997-11-26 1999-06-15 Miura Co Ltd Constant flow valve having check mechanism

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045039U (en) * 1983-09-06 1985-03-29 テルモ株式会社 non-return valve
JPH04137771U (en) * 1991-06-19 1992-12-22 関西日本電気株式会社 Liquid metered dispensing device
US5893842A (en) * 1993-02-05 1999-04-13 Becton, Dickinson And Company Syringe needle isolation device
JPH11159641A (en) * 1997-11-26 1999-06-15 Miura Co Ltd Constant flow valve having check mechanism

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010512206A (en) * 2006-12-13 2010-04-22 アーツナイミッテル・ゲーエムベーハー・アポテーカー・フェッター・ウント・コンパニー・ラフェンスブルク Fitting for syringe or cartridge
JP2010259546A (en) * 2009-04-30 2010-11-18 Yoshino Kogyosho Co Ltd Syringe container
JP2010273921A (en) * 2009-05-29 2010-12-09 Yoshino Kogyosho Co Ltd Syringe container
JP2013538995A (en) * 2010-09-02 2013-10-17 ロベルト・ボッシュ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Fluid flow throttling device and corresponding fluid supply piston pump
US9726159B2 (en) 2010-09-02 2017-08-08 Robert Bosch Gmbh Arrangement for throttling a fluid flow, and corresponding piston pump for delivering fluids
JP2016509912A (en) * 2013-03-15 2016-04-04 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Body member and diaphragm material for medical devices
KR20200145164A (en) * 2019-06-21 2020-12-30 한국수력원자력 주식회사 Flow control device
KR102231429B1 (en) * 2019-06-21 2021-03-25 한국수력원자력 주식회사 Flow control device

Also Published As

Publication number Publication date
TW469138B (en) 2001-12-21
AU2401601A (en) 2001-07-09

Similar Documents

Publication Publication Date Title
CA2565531C (en) Multi-chamber, sequential dose dispensing syringe
JP5160623B2 (en) Push-in displacement cleaning syringe
KR101124390B1 (en) Flush syringe having anti-reflux features
US6068011A (en) Control of fluid flow
JPH09182790A (en) Adapter with valve for medical access device
KR101122531B1 (en) Device of charging medical liguid and controlling flow thereof and medical liquid injection apparatus comprising the same
US20010020787A1 (en) Connector having an inner displacement member
JP2006500161A (en) Disposable syringe
US20100249725A1 (en) Medical Valve with Multiple Variable Volume Regions
WO1998039594A1 (en) Control of fluid flow
JPH1015079A (en) Adapter with valve for medical instrument
JP2000514316A (en) Multi-stage fluid injection device and method
CA2145868A1 (en) Accordion container for chemical
JPWO2004011345A1 (en) Discharge member and container comprising the same
KR101124387B1 (en) Flush syringe having anti-reflux stopper
WO2001047583A1 (en) Check valve, and syringe using the same
KR101830639B1 (en) Syringe
JP2002331032A (en) Backflow prevention tool and manufacturing method thereof and medical tool using the same
WO2013038619A1 (en) Connector valve body and connector
WO2003000170A1 (en) Mouth member for mixed filling processing and infusion container using the mouth member
WO2002000160A1 (en) Liquid lead-out tool, and liquid vessel connector using the same
JP3744986B2 (en) Catheter valve device
JP4433141B2 (en) Medical mixed injection tube
JP2004275472A (en) Medical valve
US20230277835A1 (en) Medical connector

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA CN ID JP KR SG US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref country code: JP

Ref document number: 2001 548169

Kind code of ref document: A

Format of ref document f/p: F

122 Ep: pct application non-entry in european phase