TWI294396B - Delivery device and container provided with the same - Google Patents

Description

1294396 (1) Field of the Invention The present invention relates to a conveying device for conveying a liquid contained in a container when the container is pressed, the container being provided with the conveying device Technique A container for dripping a liquid contained therein, such as an eye dropper, utilizes a transfer device 150 as shown in Figs. 41(a) and (b). The transfer device 150 is mounted on the mouth 152a of the container body 152. The container body 150 has an outlet opening 151 whose inner diameter is set such that the liquid can be transferred by pressing the container 152, and the liquid is caused when the container body 152 is not pressed. Not being conveyed, and a size of the outlet opening 153 is set to hold the liquid in the form of liquid 154. The container shown in Figure 41 has a high probability that the outlet opening 153 is contaminated by bacteria such as bacteria and dust. Taking an eye drop as an example, in particular, it is highly probable that the outlet opening 153 acquires an organism via contact with the cornea and/or the eyelid. After the liquid is transferred from the container, the outside air enters through the outlet opening 153 to restore the compressed deformation body to the original shape, during which the micro-objects and dust that have been taken on the outlet opening 153 may be This liquid (ophthalmic solution) 155 carries 'this liquid remains in the outlet opening and returns to the placket 152' as shown in Fig. 42(a),). Reference numeral 156 in Fig. 42 (b) denotes a bubble in the liquid (eye drops) 155. Because the entry of microorganisms and dust into the container body may cause the micro-gas 52 to be contained in the specific am body drop (b is degraded or deteriorated by the liquid in its -4-(2) 1294396, and is contained in the eye dropper. The ophthalmic solution includes a disinfectant such as ammonium benzyl chloride and p-hydroxybenzene. However, there is a problem in that it is difficult to specify a component containing a sterilizer depending on the type of ophthalmic solution, and This sterilizer may cause side effects such as allergic reactions to the eye drops. For this reason, efforts have been made to avoid or reduce the use of disinfectants. For example, a small amount of ophthalmic solution is contained without a disinfectant. Eye drops have been sold on the market for a while. Although such eye drops can eliminate the use of disinfectants, high cost limits their application and prohibits a wide range of applications. Japan's first published patent application No. 2002- No. 8005 5 discloses a conveyor provided with a filter which utilizes a so-called layered bottle having an outer layer and an inner layer which can be layered on the outer layer. In order to prevent the outside air from flowing into the container through the outlet opening after the transfer of the liquid, the liquid in the container may be prevented from being contaminated by bacteria or the like. However, it is necessary to provide an inner container which is internally The layer is constructed and easily deformed to accommodate a change in pressure in the container due to the transfer of the liquid, which results in an increase in the manufacturing cost of the container. Japanese Laid-Open Patent Application No. 2001-179017 and Japanese Laid-Open Patent Application No. 2001 - No. 206454 discloses an antibacterial container having a porous filter having a hole small enough to prevent passage of bacteria and dust and installed at its outlet opening. In this case, however, when the porous filter is in a liquid After the humidification, there is a possibility that the filter contains the solution contained in the liquid. A suspension can be used as the solution for the eye-5 - (3) 1294396 depending on the application, in which case the problem of the filter is more likely Occurs. Again, 'However, Japan’s first public patent application No. 2001-179017 and Japan’s first public patent application The container disclosed in No. 200 1 - 206454 utilizes a porous filter made of sintered metal or sintered resin, in which case fine particles of the sintered material may be transported together with the liquid.

Against this background, it is an object of the present invention to provide a conveying device which is mounted at the mouth of a container and conveys the liquid contained therein in the form of droplets which can prevent the liquid from flowing back and, after transporting the liquid, reach Aseptically enter the container. Another object of the present invention is to provide a container capable of removing or reducing the use of an antibacterial agent for the purpose of preventing deterioration or deterioration of the contained liquid, and achieving smooth transfer of the liquid even when the liquid system suspension is contained. Does not block the exit opening.

[Conveying device] The conveying device of the present invention achieves the above object, comprising: an outlet portion having a substantially bottom tubular shape or a substantially bowl shape having an outlet hole at a bottom portion thereof; a valve member being made of an elastic material Produced, when no liquid pressure is applied thereto from the upstream side, the flow path in the outlet portion that closes the outlet hole and/or the outlet hole is closed, and when liquid pressure is applied from the upstream side Upper, deforming and opening the outlet hole and/or the flow path, the side of the outlet hole is defined as a downstream; and a venting hole communicating with the outlet hole -6 - (4) 1294396, the outlet hole is via an air filter And at a position upstream of the valve element, wherein the deformation of the valve element is achieved by a liquid pressure lower than a liquid passing pressure of the air filter, and the opening of the outlet hole and/or the flow path cannot be The outside is achieved by the air of the air filter passing through the pressure. In the conveying device of the present invention, the valve member for controlling the opening and opening of the outlet hole and the flow path is made of an elastic material, and when no liquid pressure extends from the upstream side to the upper side, the outlet hole and/or the flow is closed. And, when the liquid pressure is pressed from the upstream side, deforming and opening the outlet hole and/or the flow path, and when the outlet hole and/or the flow path are opened, the outlet hole and the upstream side of the outlet portion (especially such as The container body of the eye drop device connected to the conveying device of the present invention is brought into communication with each other, whereby the transfer of the liquid from the outlet opening is achieved, in order to achieve the transfer of the liquid from the outlet opening by the conveying device of the present invention, for example, a pressure can be Applied to a container body such as an eye drop, the container system is coupled to a transfer device. When the pressure is applied, the valve member of the conveying device receives the pressure (medical liquid or the like) containing the liquid from the upstream side, so that the valve member is deformed' and the outlet port and/or the flow path are opened. After the completion of the conveying operation, the deformed container body draws in outside air through the vent holes in order to restore the original shape. When the conveying device of the present invention is used, since the air filter is installed in the vent hole communicating with the flow path containing the liquid, the aseptic inlet of the air can be achieved after the conveying operation. The negative pressure 'produces the effect of recovery of the valve member 4 1294396 (5) which is connected to the container body of the conveying device so as to inhale the outside air after the completion of the conveying operation. As a result, when the pressure on the container body is removed, the gap (flow path) formed by the transfer operation between the valve member and the outlet portion is immediately closed, and therefore, the valve member function in the conveying device of the present invention Such as a check valve. The conveying device of the present invention can be implemented as described in the first to fifth embodiments below.

(First Embodiment) A first conveying apparatus according to the present invention comprises: an outlet portion having a substantially bottom tubular shape or a substantially bowl shape having an outlet hole at a bottom portion thereof; a valve member made of an elastic material And disposed at the outlet portion, when no liquid pressure is applied thereto from the upstream side, closing the outlet hole, and 'when liquid pressure is applied thereto from the upstream side, encountering compression deformation and opening the same An outlet hole, the side of the outlet hole being defined as a downstream; a locking member disposed at the outlet portion to define a flow path between itself and the inner surface of the outlet portion, and fixing the valve member upstream; and a venting opening, The outlet hole is communicated, and the outlet hole is disposed at an upstream position of the valve element via an air filter, wherein the compression deformation of the valve element is performed by a liquid pressure lower than a liquid passing through the air filter. This is achieved, and the opening of the outlet opening and/or the flow path cannot be achieved from the outside by the air passing pressure of the air filter. In the first conveying device, the valve member made of an elastic material and disposed at the outlet portion is operated in connection with an outlet hole as a valve seat to control the closing and opening of the flow path. When no liquid pressure extends from the upstream side to the upper side, the valve -8 - (6) 1294396 element closes the outlet hole, and when the liquid pressure is pressed from the upstream side, compression deformation is performed to open the outlet hole, and the outlet hole is opened. When it is opened, the outlet hole and the flow path formed between the inner surface of the outlet portion and the lock member communicate with each other, thereby achieving the transfer of the contained liquid from the outlet portion. In the first transfer device, the transfer of liquid from the exit orifice can be achieved by applying a pressure to the container body, the container system being coupled to a transfer device similar to that previously described. Such characteristics and operation are similar to those described above, wherein when the valve element returns to its original shape after the transfer operation, the sterile entry into the container via the air filter air can be achieved and the negative pressure of the outside air is accelerated. Recovery of the deformed valve element (thus, the valve element can be acted upon as a check valve). In the first transfer device, since the compression deformation of the valve member is achieved by the liquid pressure lower than the pressure required to pass the liquid through the air filter, the liquid leakage in the air filter does not occur during the transfer operation. In the meantime, since the opening of the outlet hole and/or the flow path communicating with the outlet hole cannot be achieved by the pressure required to allow air to pass through the air filter from the outside, the outside air does not pass through the outlet hole, instead of passing through the filter. The entry does not occur during the recovery period of the liquid leaking out of the container body via the outlet hole. As a result, according to the first conveying device of the present invention, the conveying operation and recovery of the container body after the conveying operation can be smoothly achieved, while at a high level, the backflow of the liquid which has been conveyed from the outlet port and the microorganisms brought to the upstream by the liquid are prevented. And the entry of dust. - In the first transfer device (the valve member and the locking member are preferably formed integrally as a whole - 9 - (7) 1294396. By integrally forming the valve member and the locking member, the process of the transfer device can be made efficient. The method for integrally forming the valve member and the locking member includes, for example, multi-color molding and insert molding. [Second Embodiment] A second conveying device according to the present invention comprises: an outlet portion having a substantially bottom tubular shape Or substantially bowl-shaped, the shape has an outlet hole at the bottom thereof; a valve seat fixed to the outlet portion; a valve member substantially made of a resilient material, and the valve member is fixed to the inner surface of the outlet portion Upper, when no liquid pressure is applied thereto, the flow path is closed from the downstream side by the valve seat to close the flow port, and when liquid pressure is applied thereto from the upstream side, compression is performed. Deformation to open a flow path between itself and the valve seat, the outlet hole side being defined as a downstream; and a venting opening communicating with the outlet opening, the outlet opening being disposed upstream of the valve element via an air filter The compression deformation of the valve element is achieved by the liquid pressure of the liquid passing through the air filter, and the opening of the outlet hole and/or the flow path cannot be from the outside by the air of the air filter. In the second conveying device, the valve member made of an elastic material and disposed at the outlet portion is paired with the valve seat also disposed at the outlet portion to control the closing and opening of the flow path. When there is no liquid When the pressure extends from the upstream side to the upper side, the valve element contacts the valve seat, and closes the flow path connecting the outlet hole and the upstream side of the outlet portion. When the liquid pressure is pressed from the upstream side, the valve element is compressively deformed, and Forming a gap between itself and the valve seat (opening a gap between itself -10 (8) 1294396 and the valve seat). Therefore, the gap is formed between the valve element and the valve seat, and the first-class road system is formed. Intersecting between the upstream and outlet orifices of the valve element, whereby the transfer of liquid from the outlet orifice is achieved. In the second conveyor, the transfer of liquid from the outlet orifice can be achieved by applying a pressure to the vessel body. The container system is coupled to a conveyor similar to that described above. Such characteristics and operation are similar to those described above in that the valve element is sterilized via air filter air when the valve element returns to its original shape after the transfer operation. Access to the container can be achieved, and the negative pressure of the outside air is accelerated to recover the deformation of the valve element (therefore, the valve element can be acted upon as a check valve). In the second transfer device, because of the compression deformation of the valve element This is achieved by a liquid pressure lower than the pressure required to pass the liquid through the air filter, without leakage of liquid through the venting opening during the transfer operation. "Because of the exit hole and/or flow path communicating with the exit hole" The opening cannot be achieved by the pressure required to allow air to pass through the air filter from the outside, and no external air will pass through the outlet opening, rather than entering through the filter, nor will the liquid leak out of the container via the outlet hole. The recovery period of the body. As a result, according to the second conveying device of the present invention, the conveying operation and recovery of the container body after the conveying operation can be smoothly achieved, while at a high level, the backflow of the liquid which has been conveyed from the outlet port and the microorganisms brought to the upstream by the liquid are prevented. And the entry of dust. In the second transfer device, the valve member is fixed to the inner surface of the outlet portion for the purpose of accurately closing and opening the flow path. Therefore, the valve element '-11-1294 Patent & 120714 Patent Application--- Chinese Manual Amendment Page is a monthly change page (9) 1^, —, and the exit portion is preferably integrally formed. However, this architecture is not limited. The process of manufacturing the transfer device can be made more efficient by integrally forming the valve member and the outlet portion. Methods for integrally forming the valve member and the outlet portion include, for example, multi-color molding and insert molding. [Third Embodiment] A third conveying apparatus according to the present invention comprises: an outlet portion having a substantially bottom tubular shape or a substantially bowl shape having an outlet hole at a bottom portion thereof; a valve member made of an elastic material And disposed at the outlet portion, when no liquid pressure is applied thereto from the upstream side, closing the outlet hole or a flow path communicating with the outlet hole, and when liquid pressure is applied thereto from the upstream side Enlarging deformation to open the outlet hole or flow path, the outlet hole side is defined as a downstream; and a vent hole communicating with the outlet hole, the outlet hole being disposed upstream of the valve element via an air filter a position in which the expansion deformation of the valve element is achieved by a liquid pressure lower than a liquid passing through the air filter, and the opening of the outlet hole and/or the flow path cannot be from the outside by the air filter The air is reached by pressure. In the third conveying device, the valve member made of an elastic material and disposed at the outlet portion controls the opening and opening of the outlet hole or the flow path. When no liquid pressure extends from the upstream side to the upper side thereof, the valve element closes the outlet hole or the flow path communicating with the outlet hole, and when the liquid pressure is pressed from the upstream side, the expansion deformation is performed and the outlet hole or flow is opened. road. When the outlet orifice or flow path is opened, the flow path between the upstream and outlet orifices of the outlet member is established to communicate, thereby achieving the transfer of -12-(10) 1294396 liquid from the outlet orifice. In the third transfer device, the transfer of liquid from the exit orifice can be achieved by applying a pressure to the 'container body which is coupled to a transfer device similar to that previously described. Such characteristics and operation are similar to those described above, wherein when the valve element returns to its original shape after the transfer operation, the sterile entry into the container via the air filter air can be achieved and the negative pressure of the outside air is accelerated. Recovery of the deformed valve element (thus, the valve element can be acted upon as a check valve). In the third transfer device, since the swelling deformation of the valve member is achieved by a liquid pressure lower than the pressure required to pass the liquid through the air filter, leakage of the liquid in the vent hole does not occur during the transfer operation. . Meanwhile, since the swelling deformation of the valve element is not caused by the external pressure according to the structure (thus, the swelling deformation cannot be achieved by the pressure equal to the air pressure from the outside through the air filter), and does not occur. The entry of outside air through the outlet opening of the venting opening does not occur during the recovery of the corresponding leakage of liquid through the outlet opening from the container body. As a result, according to the third conveying device of the present invention, the conveying operation and recovery of the container after the conveying operation can be smoothly achieved, while at a high level, the backflow of the liquid which has been conveyed from the outlet port and the microorganisms brought to the upstream by the liquid and The entry of dust. In the third conveying device of the present invention, the valve member has a valve body fixed to the flow path, and a projection formed at an end on the side of the outlet hole. A convex portion located at the tip end of the valve body engages with a ridge formed on the inner wall of the flow path from the upstream to close the flow path, and the ridge communicates with the outlet hole. -13- (11) 1294396 The valve body is preferably swollen from the upstream side toward the downstream under the effect of liquid pressure to form a void on the inner surface of the convex portion and the flow path of the tip end of the valve body. Between the ridges.

In this example, when no liquid pressure extends from the upstream side to the upper side, the convex portion at the tip end of the valve body engages with the ridge provided on the inner surface of the flow path from the downstream side, so that the flow path is closed. . When the liquid pressure is applied, the valve member expands toward the downstream of the meshing position, thereby opening the gap between the convex portion at the tip end of the valve body and the ridge portion provided on the inner surface of the flow path. When the transfer operation is completed and the liquid pressure is removed from the valve element, when the valve element returns to the original shape, the convex portion at the tip end of the valve body returns upstream to again with the ridge provided on the inner surface of the flow path The parts are engaged, thereby closing the flow path. The recovery of the deformed valve element is accelerated by a negative pressure which is generated by the recovery of the container body which has been deformed by the conveying operation, and which has the effect of sucking outside air as described above.

[Fourth Embodiment] A fourth conveying apparatus according to the present invention comprises: an outlet portion having a substantially bottom tubular shape or a substantially bowl shape having an outlet hole at a bottom portion thereof; a valve member made of an elastic material And contacting the outlet portion on the outer surface thereof 'when no liquid pressure is applied thereto from the upstream side, the outlet hole is sealed, and when liquid pressure is applied thereto from the upstream side' Performing a swelling deformation to open the outlet hole or flow path, the outlet hole side being defined as a downstream; and a vent hole communicating with the outlet hole, the outlet hole being disposed upstream of the valve element via an air filter , wherein the expansion deformation of the valve element-14 - 1294396 (12) is achieved by a liquid pressure lower than the liquid passing through the air filter, and the opening of the outlet hole cannot be from the outside by the air The air of the filter is achieved by pressure. In the fourth transfer device, the valve member made of an elastic material and disposed to be in contact with the outlet portion on the outer surface thereof controls the opening and closing of the outlet hole. When no liquid pressure extends from the upstream side to the upper side, the valve member closes the outlet hole, and when the liquid pressure is pressed from the upstream side, the expansion deformation toward the outside (downstream side) of the outlet portion is performed (by this orientation) The valve element is bent outside and the outlet hole is opened. When the outlet port is opened, the flow path between the upstream side of the outlet member and the outlet port is established to communicate with each other, thereby achieving the transfer of the liquid from the outlet port. In the fourth transfer device, the transfer of liquid from the exit orifice can be achieved by applying a pressure to the container body, the container system being coupled to a transfer device similar to that previously described. Such characteristics and operation are similar to those described above, wherein when the valve element returns to its original shape after the transfer operation, the sterile entry into the container via the air filter air can be achieved and the negative pressure of the outside air is accelerated. Recovery of the deformed valve element (thus, the valve element can be acted upon as a check valve). In the fourth transfer device, since the swelling deformation of the valve member is achieved by a liquid pressure lower than the pressure required to pass the liquid through the air filter, leakage of the liquid in the vent hole does not occur during the transfer operation. . Meanwhile, since the swelling deformation of the valve element is not caused by the external pressure according to the structure (thus, the swelling deformation cannot be achieved by the pressure equal to the air pressure from the outside through the air filter), and does not occur. The outside air i -15- (13) 1294396 gas enters through the exit hole of the venting hole, and the recovery period of the liquid leaking out of the container body through the outlet hole does not occur. As a result, according to the fourth conveying apparatus of the present invention, the conveying operation and recovery of the container after the conveying operation can be smoothly achieved, while at a high level, the backflow of the liquid which has been conveyed from the outlet hole and the microorganisms brought up to the upstream by the liquid and The entry of dust. In the fourth conveying device of the present invention, the outlet hole is defined by a substantially disk-shaped valve seat fixed to the outlet portion and an inner wall surface of the outlet portion of the holding valve seat, however, the valve member has a substantially annular shape The thin portion is closed by the thin portion being brought into contact with the valve seat from the outer surface of the outlet portion. The thin wall portion of the valve member is preferably swelled toward the downstream under liquid pressure to open the outlet port, the outlet port side being defined as downstream. In this case, when no liquid pressure extends from the upstream side thereto, the thin wall portion of the valve member comes into contact with the substantially dish-shaped valve seat to close the outlet hole. When the liquid pressure is applied, the valve member is swollen and deformed toward the downstream (bending to the outside of the outlet portion), thereby opening an outlet hole defined between the substantially disc-shaped valve seat and the inner wall surface of the outlet portion, Hold the valve seat. When the transfer operation is completed and the liquid pressure is removed from the valve member, the thin portion of the valve member again comes into contact with the substantially disc-shaped valve seat to close the flow path. The recovery of the deformed valve element is accelerated by a negative pressure having the effect of inhaling the outside air, and is caused by the recovery of the container body, which has been deformed by the conveying operation, as described above. In the fourth transfer device of the present invention, the valve member is preferably integrally formed outside the outlet portion, which makes the process of manufacturing the transfer device more efficient. Use -16- 1294396 (14) to integrally form a valve element and produce 'but not limited to this. [Fifth Embodiment] According to the fifth substantial bottom tubular or substantially bottom portion of the present invention; a valve element The body and a substantially annular thin wall are at the outlet portion, but the thin wall; a cylindrical valve member supporting hole and the valve member; and the through-system is defined by an air filter and the hole side is downstream, and the supporting member thereof The peripheral contact, when closed, closes the outlet opening such that when the liquid pressure is applied to the rising deformation system is achieved by the air being lower than the air, and the valve outlet element passes the pressure and the valve element in the fifth conveying device has The thin portion is exposed between the outer valve element support members of the outlet portion. The method of controlling the outlet opening portion for the valve seat includes multi-color molding and insert molding. The conveying device comprises: an outlet portion having a bowl shape, the shape having an outlet hole made of a material thereof and having a substantially annular valve portion disposed at a tip end of the former, the valve system fixing portion passing through the An outer member exposed to the outlet portion is disposed at the outlet portion to define an outlet vent hole communicating with the outlet hole, the outlet hole being disposed at an upstream position of the valve member, wherein the valve member has a thin wall portion at the outlet The valve element is such that when no liquid pressure is applied from the upstream side, the thin wall portion is swollen and deformed, and the outlet hole is opened at the above time, and the liquid of the swell filter of the thin wall portion is not opened by the pressure liquid pressure hole. This is achieved by the air from the outside. The elastic material is disposed and disposed at the outlet portion in a state of being fixed through the hole provided at the bottom of the outlet portion to define the opening and opening of the outlet hole in itself and the thin wall portion using the circular valve member supporting member. When no liquid pressure extends from the upstream side of the -17-(15) 1294396, the thin wall portion of the valve member comes into contact with the outer periphery of the valve element support member to close the outlet opening. When the liquid pressure is applied thereto from the upstream side, the thin portion is swelled toward the outside (downstream side) of the outlet portion, and thereby the outlet hole is opened. When the outlet port is opened, the flow path between the upstream of the outlet member and the outlet port is established to communicate, thereby achieving the transfer of liquid from the outlet port. In the fifth transfer device, the transfer of liquid from the outlet port can be achieved by applying a pressure to the container body, and the container system is connected to a transfer device similar to the one described above. Such characteristics and operation are similar to those described above, wherein when the valve element returns to its original shape after the transfer operation, the sterile entry into the container via the air filter air can be achieved and the negative pressure of the outside air is accelerated. Recovery of the deformed valve element (thus, the valve element can be acted upon as a check valve). In the fifth transfer device, since the swelling deformation of the valve member is achieved by a liquid pressure lower than the pressure required to pass the liquid through the air filter, leakage of the liquid in the vent hole does not occur during the transfer operation. . In the meantime, because the expansion deformation of the valve element is not caused by the external pressure according to the structure (thus, the swelling deformation cannot be achieved by the pressure equal to the air pressure from the outside through the air filter), and does not occur. The entry of outside air through the outlet opening of the venting opening does not occur during the recovery of the corresponding leakage of liquid through the outlet opening from the container body. As a result, according to the fifth conveying apparatus of the present invention, the conveying operation and recovery of the container after the conveying operation can be smoothly achieved while at the high level, the backflow of the liquid which has been conveyed from the outlet hole and the micro-upstream from the liquid are prevented. 18- (16) 1294396 Entry of living things and dust. In the fifth conveying device of the present invention, the valve member supporting member preferably has a flange on the upstream side of the circular portion thereof so that when no liquid pressure is extended thereto, the valve body of the valve member The flange contacts to close the flow path, and when liquid pressure is applied thereto, bending deformation is performed to open the flow path between itself and the valve element supporting member.

In this example, when no liquid pressure extends from the upstream side thereto, the thin portion of the valve member not only contacts the outer periphery of the valve element support portion to close the outlet hole, but also brings the valve body into the valve member. The flange contacts to close the flow path. Therefore, the closing of the exit hole is more determined. When the liquid pressure is applied from the upstream side, the valve element not only causes the thin-walled portion to expand and deform toward the outside (downstream) of the outlet portion, but also compresses and deforms the valve body, thereby forming (turning on) itself. A flow path with the flange of the valve element support member. When the outlet port and the flow path are opened as described above, the flow path between the upstream of the valve member and the outlet port is established to communicate with each other, so that the liquid is delivered from the outlet port.

In the fifth transfer device and in the preferred embodiment thereof, the recovery of the deformed valve member is accelerated by the negative pressure generated by the recovery of the container body after the removal of the liquid to complete the transfer operation, the container body It has been deformed by the transfer operation and sucks in outside air as described above. In the fifth conveying device of the present invention, the valve body of the valve member is preferably integrally formed on the inner surface of the outlet portion, which makes the process of manufacturing the conveying device more efficient. Methods for integrally forming the valve member and the outlet portion include, but are not limited to, multi-color molding and insert molding. -19- (17) 1294396 [Antibacterial treatment] In the conveying device of the present invention, the valve member and/or the outlet port are preferably subjected to an antibacterial treatment. When the valve member and/or the outlet orifice are subjected to an antibacterial treatment, the effect of preventing the propagation of bacteria can be achieved for the liquid remaining in the vicinity of the outlet port after the transfer operation is completed. The member subjected to the antibacterial treatment can be selected depending on the constitution of the conveying device. The antibacterial treatment can be applied to various members such as, but not limited to, the entire outlet portion, the valve seat, the container body, the surface of the cover covering the outlet portion (especially the inner surface contacting the outlet portion), provided on the inner side of the cover Water absorbing material (sponge, cloth, paper, hydrogel, etc.). The antibacterial treatment can be carried out by mixing a chemical such as a disinfectant or an antibacterial agent into an elastic material such as a thermoplastic elastomer (made of a valve member) or into a resin material of an outlet portion, an outlet hole, and a valve seat. Or in a raw material made of a water-absorbent material or the like, or by coating a surface of a valve member, an outlet portion or the like in which a chemical has been formed, or by applying a surface treatment such as a decane coupling or a selenium coating. Used on the water-absorbing material used to form the valve element, the outlet portion, the material of the cover or the cover. The antibacterial treatment can be applied to a hydrosol containing an acrylamide polymer and a water-swellable clay mineral by coating its surface with selenium. [Liquid filter] The conveying device of the present invention preferably has a liquid filter disposed upstream of the U-hole or upstream of a position where the flow path is opened/closed by the valve member. By arranging the liquid filter, it is possible to surely prevent or limit the residual liquid 20 - (18) 1294396 body from entering (returning) the container body connected to the transfer device, if the residual liquid remaining near the exit hole of the outlet portion is subjected to Microbial or ash contamination. That is, it is preferred to configure the liquid filter to prevent or restrict contaminants from entering the container connected to the conveyor. A liquid filter having a fine mesh of about 0-2 to 0.45/zm makes it difficult to apply the transfer device of the present invention to a container containing a suspension. On the other hand, this makes it possible to surely prevent or restrict the entry (reflow) of residual liquid into the container body of the conveying device of the present invention, if the residual liquid contaminated with microorganisms or dust flows back through the outlet port. A liquid filter having a coarse mesh of 10 to 1 makes it possible to also apply the transfer device of the present invention to a container containing a suspension. In this case, this does not require consideration of the loading of the liquid filter by the suspension, and this effect can be attained because the solvent in the container is prevented from evaporating and, as a result, the suspended component can be prevented from coagulation. Near the exit hole. Also, because even a liquid filter having such a coarse mesh can suppress the passage of microorganisms to a certain extent, it is possible to restrict the residual liquid from entering the container body to a certain extent, if the residual liquid contaminated by microorganisms or dust passes through the exit hole. And enter (return). [Container] The container of the present invention for achieving the above object has the delivery device of the present invention installed at the mouth of the container body. The container of the present invention is suitable for use as an eye drop for accommodating an ophthalmic solution. - 21 - (19) 1294396 [Embodiment] Hereinafter, a conveying device of the present invention and a container provided with the same will be described with reference to the accompanying drawings. [First conveyor and container] The first conveyor 10 according to the invention comprises an outlet portion 11 having a substantially bottom tubular shape (or substantially bowl-like) having an outlet opening 12 at its bottom; a valve element 13, configured At the outlet portion 11, when no liquid pressure is applied thereto from the upstream side U, the outlet port 12 is closed, and when the liquid pressure is pushed from the upstream side U, compression deformation is performed and the outlet port 1 2 is opened; The solid member 14 is disposed at the outlet portion 1 1 to define a flow path 15 between itself and the inner surface lid of the outlet portion, which fixes the valve member 13 on the upstream side U; and, the vent hole 16 6 is filtered through the air The device 1 is in communication with a flow path provided at a position upstream of the valve element 13. The outlet port 12 is normally closed by the valve member 13, however, when the liquid pressure is applied to the valve member 13 from the upstream side U via the flow path 15, the valve member 13 is compression-deformed to form a void. Between the outlet opening 12 of the outlet portion ij and the valve element 13. This enables the liquid contained in the container to be conveyed through this gap. The valve element 13 is fixed by the lock member 14 in the transfer device 1 and the gap between the lock member 14 and the inner surface of the outlet portion is a liquid flow path 15. The outlet portion 11 comprises two members: an outlet portion 11a having an outlet opening 12, and a link portion 1 1b disposed upstream of the outlet portion 丨 & -22- (20) 1294396 side U And connected to the mouth of the container, because the air filter 17 needs to be installed in the vent 16 . The outlet portion body a and the link portion 1 1b are integrated with the air filter 17 loaded into the joint 1 1 c using an engaging mechanism such as ultrasonic welding. The first transfer device 10 is, for example, 'attached to the mouth of the container body 21, as shown in Fig. 2. In the example of the container 20 shown in FIG. 2, the delivery device 10 is attached to the neck 22 of the container 20 via a plug 23. Plug 23 is slidably inserted into the neck 22 of the container 20, as shown in Figures 2 and 3. Fig. 2 is a cross-sectional view of the container 20 in a use state, and Fig. 3 is a cross-sectional view of the container 20 before being sealed. In the unsealed state as shown in Fig. 3, not only the cover 26 is attached to the outlet portion 11, but also the stopper 27 is fitted between the conveying device 10 and the container body 21. Therefore, the conveying device 10 is slightly inserted into the container body 21. In this state, the tip portion 23a of the plug 23 is in contact with the flange 19, and the flange 19 is disposed on the inner surface of the conveying device 10. As a result, the conveying device 10 is blocked by the flange 19 and the tip portion 23a of the plug 23, whereby the liquid in the container body 21 can be retained in a high-level aseptic state, and the deterioration of the liquid in the container can be prevented. (oxidation). The sequence of the transfer operation of the first transfer device of the present invention and the container provided with the device is shown in Figs. 4 and 5. Fig. 4 (a) shows the state in which the pressure is not applied to the container body 21, and the valve member 13 of the conveying device closes the outlet hole 12. As a result, the liquid 24 contained in the container body 21 remains in the container body 21 and the conveying means, and is not conveyed through the outlet portion 11. Fig. 4'(b) shows the state of the container body 21 under application of pressure. In this state, pass <» - 23 - (21) 1294396 The valve element 13 of the delivery device is at a pressure from the liquid 24 containing the liquid 24, and thus the compression deformation of the valve element 13 is performed to open the outlet hole 12, whereby The internal liquid is transferred in the form of a drop 25 (Fig. 5 (a) shows the state following the state shown in Fig. 4 (b). In this state, the pressure on the container body 21 is removed. In this state, 'because the valve member 13 of the conveying device does not receive the pressure of the liquid 24', the valve member 1 3 returns to the original shape of the state without pressure 'by this' again closing the outlet port 12. Fig. 5(b) shows the state following the state of Fig. 5(a). In this state, the valve member 13 returns to the original shape of the state without pressure 'because the pressure on the container body 21 is removed. In this state, 'because the valve element 13 of the conveyor closes the outlet opening 1 2 'the outside air enters the container body 21 via the venting opening 16 only to the first conveyor 10' and the container 20' provided with the device In another embodiment, as shown in FIG. 6, the liquid filter 18 is disposed on the flow path 15 that communicates with the outlet port 12. As a result, if the residual liquid contaminated by microorganisms or dust flows back from the outlet port 12 as previously described, it is possible to prevent or restrict the entry of the residual liquid into the container body 21 connected to the conveying device 1'. The first transfer device of the present invention may also, for example, cause the valve members 1 3 a and 13b to have the cross-sectional configuration shown in Figures 7 and 8. That is, the end of the valve member 13 exposed through the outlet opening 12 may be flat as shown in Fig. 7 or the valve member 13b may have a recess 13c at its tip as shown in Fig. 8. When the liquid pressure is applied from the upstream side U, the valve element 13b having the structure shown in Fig. 8 is more likely than the valve element having no recess 1 3 c (the valve elements 13 3, 13a shown in Figs. 1 and 7). Pressurize -24 - (22) 1294396 to deform (and it is more likely to open the exit hole 12). Further, this problem is less favored, in which the pressure of the outer side of the outlet hole 12 is inadvertently opened, and thus it is more advantageous to be smooth and prevent backflow. [Second Transfer Device and Container] According to the second transfer device 30 of the present invention, there is a substantially bottom tubular shape having an outlet hole 32-shaped valve member 33 disposed at the outlet portion 31; the open end 3 of the valve seat 34 The 1 d side is loaded, and when the outlet hole 32 is male, it is in contact with the valve element 3 3 on the upstream side U, and the air filter 37 communicates with the upstream flow path 35 provided in the valve element 33, such as 9 (cross-sectional view) and FIG. 10 (shown. The outlet portion 31 includes two members: an outlet portion body port hole 32, and a link portion 31b which is disposed on the outlet portion side U and is connected to the mouth of the container, Since it is necessary to install the air I vent hole 36, the joint mechanism of the outlet portion 31a and the link portion 31b is ultrasonically integrated with the air filter 37 connected to the flange 31f. The conveyor shown in Figs. 30. The overall assembly of the outlet member 3 3 is formed by combining at least a portion of the inner surface 31e of the annular valve member 31a, as shown in the figure. Figure 1 1 (a) is a portion indicated by a broken line I , the valve element 13b is more smoothly transferred from the outlet portion 1 1 : the outlet portion 3 1 is at the bottom thereof; The portion 31 L is defined as the downstream side D vent 3 3, the position of the side U through: an exploded cross-sectional view 31a, which has an outer air filter 37 of the body 31a, such as a super; head 3 lc) insertion portion The body 3 1 a and the valve 33 and the outlet portion are as shown in the flat-line vent of Fig. 11. The through hole -25- (23) 1294396 is covered with an air filter 37. Fig. 1 1 (b) is a bottom view of the overall combination of the outlet portion body 3 1 a and the valve member 3 3, wherein the outlet portion body 31a has a through hole 31g (injection hole) passing through the bottom portion thereof. The outlet portion 3 1 a can be formed, for example, by injecting a resin into a mold. The outlet portion 31a and the valve member 33 can 'replace (or move) the mold (movable mold) on the open end 31d of the outlet portion 31 after the above-described injection (refer to FIG. 10), and then pass through the outlet portion. The injection hole 3 1 g at the bottom of the body 3 1 a is injected and formed by injecting a thermoplastic elastomer. When the valve element 33 is integrally molded, the material is injected through the open end 31d of the outlet portion, and the injection hole 31g becomes unnecessary. In the conveying device 30 shown in Figs. 9 and 1 , the valve seat 34 is attached to the outlet portion 31a from the upstream side U of the tubular body 34c, and the tubular body 34c has a flange 34d and a valve seat 34a. The opening on the opposite side of the flange 34 side of the tubular body 34c is disposed as shown in plan view (a) and bottom view (b) of Fig. 12. The portion indicated by reference numeral 34b having the pocket portion of the annular valve member 33 together defines a flow path 35 for the liquid. Reference numeral 34e represents a joint between the tubular body 34c and the valve seat 34a. In the integrally molded body shown in Fig. 1 1 (a), the valve member 33 has an annular shape. However, the valve member is not limited to the structure constituted in the circumferential direction X (annular) of the outlet portion body 31a, and may have such a structure as shown, for example, in Fig. 13 (a). It is assumed that the valve member has the structure shown in Fig. 13 (a), a first-class path (not shown) which is formed between the valve seat (not shown) and the outlet portion 3 1 a' by compression deformation of the valve member 33'. It becomes narrower than the flow path in the example in which the valve element 33 has a ring shape (Fig. 11). Therefore, its shape -26-(24) 1294396 can be determined depending on the width of the flow path required for the conveyor. Reference numeral 3le in Fig. 13 (a) represents the inner surface of the outlet portion body 31a, and 3 If' represents the flange of the outlet portion body 3ia. Fig. 13 (b) shows a valve seat portion 34' of the conveying device used for the valve member 33' having the shape shown in Fig. 13 (a). The flow path 35 of the valve seat portion 34 can be provided in accordance with the shape of the valve member 33 of the conveying device shown in Fig. 13 (a). Reference numeral 34a in Fig. 13(b) represents a valve seat. The second transfer device 30 is used when attached to the mouth of the container body 41, as shown in Fig. 14. The sequence of the transfer operation of the second transfer device of the present invention and the container provided with the same is shown in Figs. Fig. 15 (a) shows a state in which the pressure is not applied to the container body 41, and the valve member 3 3 is closed to the flow path 35 on the outlet portion body 3 1 a and the flow path 3 5 on the side of the joint 3 1 b Therefore, the passage between the outlet hole 3 2 and the container body 4 1 is closed. As a result, the liquid 44 contained in the container body 41 remains in the container body 41 and the conveying device 30, and is not transferred via the outlet portion 31. Fig. 15 (b) shows the state of the container body 41 under application of pressure. In this state, the valve element 33 is under the pressure of the liquid from the upstream side U via the flow path 35, and thus is subjected to compression deformation. As a result, a gap is generated between the valve member 33 and the valve seat 34a (in other words, the valve member is released), so that the flow path 3 5 on the side of the outlet portion 3 1 a and the flow path 3 5 on the side of the joint 3 1 b Circulate in each other. Therefore, the liquid 44 accommodated in the container body 41 is conveyed from the outlet portion 31 in the form of a drop 45. Fig. 16 (a) shows the state following the state shown in Fig. 15 (b), in which the pressure on the container body 41 is removed. In this state, since the valve member 33 of the transporting device 27-(25) 1294396 does not receive the pressure of the liquid 43, the valve member 33 returns to the original shape of the no-pressure state, whereby the valve member 33 and the valve seat 3 are closed. The gap between 4a. Fig. 16 (b) shows the state of the state following the state of Fig. 16 (a) where the container body 41 is restored to the original shape without pressure, because the pressure on the container body 41 is removed. In this state, since the valve member 33 of the conveying device closes the flow path 35, the outside air enters the container body 41 only via the vent hole 36. As shown in Figures 14 and 17, the plug 43 is slidably inserted into the neck portion 42 of the container 40. Figure 14 shows a section of the container 40 in use, while Figure 17 shows a section of the container 40 before it is sealed. In the state before the unsealing as shown in Fig. 17, the conveying device 30 is slightly inserted into the container body 41. In this state, the end 43a of the plug 43 is in contact with the flange 39, and the flange 39 is disposed on the inner surface of the outlet portion 31. As a result, the flow path 35 of the conveying device 30 is blocked by the flange 39 and the end 43a of the plug 43, whereby the liquid in the container body 41 can be kept in a high level of sterility and the liquid in the container can be prevented. Protected from deterioration (oxidation) in the process. The conveying device 30 shown in Fig. 17 has a cap portion 46h on which the cap 46 is attached to the outlet portion 31a. However, the sponge 47 is disposed on the inner surface of the cap 46 at a position in contact with the outlet hole 32 of the outlet portion 31. Since the sponge 47 absorbs the residual liquid 35' remaining in the outlet port 32 after completion of the transfer operation (refer to Fig. 16 (b)), the residual liquid can be prevented from being supplied to the next transfer operation. Reference numeral 46a represents a thread formed on the inner surface of the cover 46. -28 - (26) 1294396 In the conveying device 30 shown in Fig. 17, the open end 46b of the lid blocks the venting opening 36 of the feeding device 30. As a result, when the solution (water) or the like of the internal liquid of the container body 41 is gradually vaporized via the air filter 37, such a problem is prevented from occurring, resulting in a change in the pH of the liquid contained therein. The device is not limited to the above described devices and, for example, may have such an architecture as shown in FIG. Similar to the transfer device 30 shown in Fig. 9, the transfer device 30' shown in Fig. 18 includes an outlet portion 31 having a substantially bottom tubular shape having an orifice 32 at the bottom thereof; an annular valve member 33', Disposed in the outlet portion 31 of the valve seat portion 34, from the open end side of the outlet portion 31, and when the outlet opening defines the downstream side D, the valve member 3 3 ' on the upstream side U contacts the venting opening 36 The liquid filter 3 is connected to the flow path 35 via the air filter 37, and the liquid filter 38 is disposed on the upstream side ϋ' of the valve seat portion 34 and covers the path 35. The conveying device 30 is the same as the conveying device 10' shown in Fig. 9. The shape of the valve member 3 3 is different from the outlet 31 of the former which accommodates the outlet port 32, and the liquid filter 38 is disposed in the flow. Road 3 5 outside. [Third Conveying Apparatus and Container] The third conveying apparatus 50 according to the present invention includes an outlet portion 51' having a substantially bottom tubular shape having an outlet hole 52 at the bottom thereof, and a valve member 53 made of an elastic material And disposed at the outlet portion 5 1 (the flow path 5 5 that communicates with the outlet hole 5 2 ), when no liquid pressure is applied to the upper side from the upstream side U, the outlet hole 52 is closed, and when the liquid pressure is pushed from the upstream side U When the body is turned into a 赘3 2 flow-removing part, the pressure is -29- 1294396 (27), the expansion deformation is performed and the outlet hole 52 is opened; and the vent hole 56 is communicated with the flow path 55. The flow path 5 5 is provided at the position 'on the upstream side U of the valve element 53 via the air filter 57. The outlet portion 51 includes two members: an outlet portion body 51a having an outlet hole 52, and a link portion 51b disposed on the upstream side U of the outlet portion body 51a and connected to the port of the container because an air filter needs to be installed 57 is in the vent 56. The outlet portion 51a and the link portion 51b are integrated with the air filter 57 fitted to the flange 5 1 f (joint 5 1 c ) using an engagement mechanism such as ultrasonic welding. Figure 2 is a plan view of the outlet body 5 1 a (viewed from the upstream side U). As shown in the figure, a ridge portion (valve seat) 52b for engaging with the convex portion of the valve body 53a is provided on the bottom of the substantially tubular outlet portion body 51a. The vent hole 56 is provided at a predetermined interval in the flange 51f (joint 51c) for mounting the link portion 51b which is paired with the outlet portion body 51a, and the air filter 57 is attached to the vent hole 56 in order to achieve air. Enter aseptically. Figure 22 shows the valve element 53 and the valve element support member 54 of the lock valve element, Figure (a) shows its plan view (viewed from the upstream side U), and Figure (b) shows its bottom view (viewed from the downstream side D) . As shown in this figure, the valve element supporting member 54 used to position the valve member 53 to the outlet portion body 51a has: a pipe member 54a; a locking member 54b disposed on the bottom of the former and locking the valve member 53; The flange 54c is disposed at the open end on the opposite side and the ballast is combined with the outlet body 51a. As shown in Figs. 19 to 22, the valve member 53 is locked to the valve member supporting member 54 and then loaded into the inner surface 5 1 e of the outlet portion 5 1 a. -30- 1294396 (28) Assuming that the valve member 53 is made of an elastic material having thermoplastic properties (such as a thermoplastic elastomer), the valve member 53 and the valve member supporting member 54 can be molded or inserted by a multi-color mold. Formed as a whole. This completes the manufacture of these two components in a simple manner. In the case where the valve member 53 is made of an elastic material that is not thermoplastic, and a molding technique such as injection molding cannot be used, the valve member 53 and the valve member support member 54 can be, for example, by a valve member The support member 54 is inserted into an injection mold, and then the material is injected to mold the valve member 53 to be integrally formed. In the embodiment shown in FIG. 19, the valve member 53 includes: a valve body 53 a as a valve shaft; a convex portion 53b disposed at a tip end of the valve member body 53a as a valve head; and, a flange 53c The engaging valve body 53a and the valve element supporting member 〇 are used as an example. As shown in FIG. 23, the elastic member shown in FIGS. 19 and 20 can be inserted into the outlet portion body 5 by the valve member supporting member 54 having the valve member 53. The open end of a (refer to 5 1 d of Fig. 20) is provided to place the convex portion 53b of the valve body 53a on the ridge 5 2 b formed on the inner wall 5 2 a of the flow path of the outlet hole 52 Then, a strong pressure of the liquid or air from the upstream side U is applied, and the convex portion 53b of the valve body slides toward the outlet hole 52 to slide the convex portion 5 3 b of the valve body. The second transfer device 50 is used when attached to the mouth of the container body 61, for example, as shown in FIG. The container 60 shown in Fig. 24 has a neck 63 in which the plug 63 is fitted into the container body 61. The sequence of the transfer operation of the second transfer device of the present invention and the container provided with the device is shown in Figures 25 and 26. Fig. 2 5 (a) shows the state in which the pressure of -31 - (29) 1294396 is not applied to the container body 6 1 . In this state, the valve element 53 blocks the passage between the flow path 55 on the outlet port 52 side and the flow path 55 on the upstream side of the valve element 53, so that the passage between the outlet hole 52 and the container body 61 is closed. As a result, the liquid 64 contained in the container body 61 remains in the container body 61 and the conveying device 50, and is not transferred via the outlet portion 51. Fig. 25(b) shows the state of the container body 61 under application of pressure. In this state, the valve member 53 is under the pressure of the liquid from the upstream side U via the flow path 55, and thus is swollen and deformed toward the outlet hole 52. As a result, the convex portion 53b of the valve body 53a and the ridge portion 52b formed on the inner wall 52a of the outlet hole 52 communicate with each other, so that the liquid 64 accommodated in the container body 61 is conveyed from the outlet portion 51 in the form of the drop 65. Fig. 26 (a) shows a state following the state shown in Fig. 25 (b) in which the pressure on the container body 61 is removed. In this state, 'because the valve element 53 of the conveying device does not receive the pressure of the liquid 64 contained therein', the valve element 53 returns to the original shape of the state without pressure 'by this' closing the gap between the valve element 5 3 and the ridge 52b . Fig. 26 (b) shows the state of the state following the state of Fig. 26 (a) where the container body 61 is restored to the original shape without pressure, because the pressure on the container body 61 is removed. In this state, since the valve member 53 of the conveying device closes the position of the flow path 55 at the ridge portion 52b of the outlet portion, the outside air enters the container body 61 only via the vent hole 56. As shown in Figures 24 and 27, the plug 63 is slidably inserted into the neck 62 of the container 60. The function is similar to the function of the container 40 provided with the second conveyor 30. Fig. 24 shows a section of the container 60 in an in-use state, and Fig. 27 shows a section of the container 60 before being sealed. In Fig. 32-59 (30) 1294396 27, the reference numeral 63a shows the end of the plug 63, and the reference numeral shows the flange provided on the inner surface of the outlet portion 51. The conveying device 50 shown in Fig. 27 has a projection portion 61h on which the lid 66 is screwed to the outlet portion 51a. However, the sponge 67 is disposed on the inner surface of the lid 66 at a position in contact with the outlet hole 52 of the outlet portion 51. The opening 66b of the cover blocks the venting opening 56. The sponge 67 and the open end 66b exhibit similar functions as the container 40 provided with the two conveyors 30. Reference numeral 66a represents a thread formed on the inner surface of the cover 66. [Fourth conveying device and container] For example, as shown in Fig. 28, the fourth conveying device according to the present invention comprises: an outlet portion 71 having a substantially bottom tubular shape having an outlet 72 at the bottom thereof; and a valve member 73 to Made of an elastic material, when no liquid pressure is applied thereto from the upstream side U, the outlet port 7 2 is closed from the outside of the outlet portion 71, and the liquid pressure ' comes into contact with the valve seat 74 when the liquid pressure comes from the upstream side u The expansion deformation is performed to open the outlet hole 72; and the vent hole 76 is communicated with the flow path, and the flow path is located upstream of the valve element 73 via the air filter 77. The outlet portion 71 includes two members: an outlet portion body 71a having an orifice 72, and a link portion 71b disposed on the upper side U of the outlet portion body 71a and connected to the mouth of the container because the air filter 77 is required to be installed. Ventilation hole 76. The outlet portion 71a and the link portion 71b are integrated with the air filter 77 loaded into the flange 71f (joint 71c) using an engagement mechanism such as sonic welding. / Body surface table 70 hole body set to swim in the super-air-33- (31) 1294396 Figure 2 9 (a) is the bottom view of the outlet body 7 1 a (observed from the downstream side D) 'Figure 29 (b) is a cross-sectional view taken along line AA of Fig. 28. The outlet portion 71a has a plurality of venting holes 76 and an air filter 77, and the air filter 7 7 is filled in the flange 7 1 f (the joint 7 1 c ) has a hole similar to that shown in Fig. 21, the flange 71f ( The joint 71c) is used to mount the link portion 71b, and the link portion 7 1 b is paired with the outlet portion body 71a. The function of the air filter 77 and the venting holes 76 is similar to the example of the container 60 provided with the third conveying device 50. As shown in Figures 28 to 29, the valve member 73 is disposed on the outer surface of the bottom portion of the outlet portion in contact with the following surfaces, having a substantially bottom tubular shape or a substantially bowl shape having an outlet opening at the bottom thereof, and The bottom surface (outer surface) of the valve seat 74 defines a flow path 75 at the bottom of the outlet portion body 71a and closes the outlet portion. The valve member 73 is preferably integrally formed with the outlet portion body 71a on the outer surface of the outlet portion 71a made of resin with a thermoplastic material having thermoplasticity. The overall formation makes the process of transport 7 更 simpler. The fourth transfer device 70 is used when attached to the mouth of the container body 81, for example, as shown in Fig. 30 (a). The container 80 shown in Fig. 30 (a) has an inner plug 83 provided in the neck portion 82 of the container body 81. The function of the plug 83 is similar to the function of the container 40 provided with the second conveyor 30 or the function of the container 60 provided with the second conveyor 50. The sequence of the transfer operation of the transfer device of the present invention and the container provided with the device is shown in Figs. 30 and 31. Fig. 30 (a) shows a state in which the pressure is not applied to the trough body 81. In this state, the valve member 73 closes the flow path 75 in the outlet port -34·(32) 1294396 7 2, so that the passage between the outer side of the outlet hole 7 2 and the container body 8 1 is closed. As a result, the liquid 84 contained in the container body 81 remains in the container body 81 and the conveying device 70 without being conveyed through the outlet portion 71. Fig. 30 (b) shows a state in which the container body 81 is applied under pressure. In this state, the valve element 73 is subjected to the pressure of the liquid from the upstream side u via the flow path 75, and therefore, is swollen and deformed toward the outlet hole 72. As a result, a first-class path is formed between the valve member 73 and the valve seat portion 74, so that the liquid 84 accommodated in the container body 81 is conveyed from the outlet portion 7 in the form of a drop 85. Figure 3 1 (a) shows the next _ 3 The state of the state shown in 0 ( b ). The pressure on the container body 81 is removed. In this state, since the valve member 73 of the conveying device does not receive the pressure of the liquid 84, the valve member 73 returns to the original shape in the no-pressure state, whereby the gap between the valve member 73 and the valve seat 74 is closed. Fig. 3 1 (b) shows the state of the state following Fig. 31 (a), in which the container body 81 returns to the original shape of the pressureless state because the pressure on the container body 81 is removed. In this state, since the valve member 73 of the conveying device closes the flow path 75 between the valve member 73 of the outlet portion 71a and the valve seat 74, the outside air enters the container body 81 through only the vent hole 76. Transfer device 70' is another embodiment of a fourth transfer device. In the case where the valve member is made of an elastic material having thermoplastic properties, the valve member 73 and the outlet portion body 71a may be integrally formed, similar to the conveying device 70 shown in Fig. 28. The valve member 73 may be formed of an elastic material other than the thermoplastic elastomer, such as a rubber which is not thermoplastic, as long as the -35-(33) 1294396 material is easily bent and is easily bent and deformed by liquid pressure. The valve element is made of an elastic material that is not thermoplastic, and thus, a molding technique such as injection molding cannot be used, and the valve element 73 can be inserted between the outlet portion body 71a' and the valve seat 74 (and tubular The body 74a) is disposed at the outlet portion 71. The conveying device 70 shown in Fig. 32 is similar to the conveying device 70 shown in Fig. 28 except that the outlet portion 7ia and the valve member 73 are different (fifth conveying device and container) as shown in Fig. 33. As shown, for example, the fifth transfer device 90 according to the present invention comprises: a tubular outlet portion 91 having a substantially bottom tubular shape (or substantially bowl-like) having a hole 91d at the bottom thereof; a valve member 93 having a substantial ring The valve body 93b and the substantially annular thin portion 93a are continuous with the former and are formed by fixing the valve body 93b in the outlet portion 91, and the thin portion 9 3a is exposed through the hole 9 1 d To the outside of the outlet portion 91; a cylindrical valve member support member 94a disposed at the outlet portion 91, and defining an outlet port 9 2 and a valve member 9 3; and, the vent hole 96 6 is in communication with the flow path 9.5 The flow path 95 is provided at a position on the upstream side U of the valve element 93 via the air filter 97. The outlet hole 92 is normally closed by the thin portion 93a of the valve member 93. However, when the liquid pressure is applied to the valve member 93 from the upstream side via the flow path 95, the thin portion 93a is swollen and deformed to generate a void. Between the thin portion 93a and the valve element supporting member 94a, thereby, the liquid in the container is conveyed via the gap 36•1294396 (34). In the embodiment shown in Fig. 33, the valve member 93 is fixed to the inner surface of the outlet portion 91a. The thin portion 93a is exposed through the hole 91d (outlet portion 91a) of the outlet portion 91. In Fig. 33, reference numeral 94c denotes a tubular member which holds the valve member supporting member 94a and the flange 94b in the outlet portion 91 (outlet portion body 91a). The valve body 93b has a sufficient thickness to be integrally formed on the inner surface of the outlet portion body 91a. The outlet portion 91 includes two members: an outlet portion body 91a having an outlet hole 92, and a link portion 91b disposed on the upstream side U of the outlet portion body 91a and connected to the port of the container because an air filter needs to be installed 97 is in the vent 96. The outlet portion 91a and the link portion 91b are integrated with the air filter 97 fitted to the joint 91c using an engagement mechanism such as ultrasonic welding. The transfer device 90 of the present invention and the sequence of transfer operations of the container 1 shown in Figs. 36 and 37 are provided. Fig. 36 (a) shows a state in which the pressure is not applied to the container body 1 0 1 . In this state, the valve member 93 of the transfer device closes the exit opening 92. As a result, the liquid 1〇4 contained in the container body 101 remains in the container body 101 and the conveying device, and is not conveyed through the outlet portion 91. Figure 3 6 (b) shows the state of the container body 1 〇 1 under the pressure applied thereto. In this state, the valve member 93 is under the pressure from the liquid containing liquid 104 in the upstream side U, and thus the expansion deformation of the valve member 93 is performed, so that the outlet hole 92 is opened and the liquid 丨〇4 is contained therein. The droplet 105 is delivered in the form of a drop 105. Fig. 3 is an enlarged view of the outlet portion 91 in the state shown in Fig. 36 (b). -37- (35) 1294396 Figure 3 7 (a) shows the state following the state shown in Figure 3 6 (b). The pressure on the container body 101 is removed. In this state, since the valve member 93 of the conveying device does not receive the pressure of the liquid 104, the adjusting member 93 returns to the original shape of the no-pressure state, whereby the outlet port 92 is closed again. Fig. 3 (b) shows the state of the state following Fig. 37 (a), in which the container body 1 恢复 1 returns to the original shape of the pressureless state because the pressure on the container body 1 0 1 is removed. In this state, since the valve member 93 of the conveying device closes the outlet hole 92, the outside air enters the container body 101 only via the vent hole 96. In the container 100 shown in Figure 34, the delivery device 90 is attached to the neck 102 of the container 100 via a plug 103. The plug 103 is slidably inserted into the neck 102 of the container 1〇〇. Figure 34 is a cross-sectional view of the container 1 使用 in use. The state in which the end 103a of the plug 103 and the flange 99 are engaged with each other (in other words, the seal is not broken)', and the joining effect of the two members is similar to the other embodiments shown in Figs. 3, 17 and 27. The conveying device 90 shown in Fig. 35 has a cover 106 which is inserted into the outer surface of the outlet portion 91a. The cover 106 has a recessed portion 1〇8 formed in a state of being inserted into the outlet portion body 91a at a position corresponding to the outlet hole 92. The surface of the cover 106 and the exit hole 9 2 are in contact with each other in the recess 1 〇 8. The sponge 1 〇 7 is disposed around the recess 108 such that the residual liquid 1 〇 5 remaining in the exit hole 92 (refer to FIG. 37( b )) is extruded by the inner surface of the cover positioned in the recess 108 and is sponged 1 〇7 and absorbed. In the conveying device 90 shown in Fig. 35 (a), the open end 1 〇 6 b of the cover blocks the vent hole 96 of the conveying device 90. As a result, such a problem is prevented by the prevention of -38·(36) 1294396 because the solvent (water) or the like containing the liquid in the container body 101 gradually evaporates via the air filter 97, which results in the pH of the contained liquid. Awkward changes. In another embodiment of the fifth conveyor 90 shown in Fig. 39, the closing of the flow path 95 is not only by the contact of the thin portion 93a and the valve element supporting member 94a but also by the valve member supporting member 94a. This is achieved by contact with the flange 94b. As a result, the closing of the flow path 95 by the valve member 93 can be reliably achieved, but at a high level, the backflow of the residual liquid containing the microorganisms and the ash that has been conveyed from the outlet port 92 is prevented. Figure 40 is an enlarged view of the outlet portion 91 of the conveying device 90' in the state shown in Figure 38. In the fifth conveying device 90, 90', a liquid filter (not shown) may be provided upstream of the position where the flow path 95 is opened and closed (contact position between the thin portion 93a and the valve element supporting member 94a) , the valve body 93b, the contact position with the flange 94b). The efficacy of configuring the liquid filter is similar to the examples of the other embodiments shown in Figures 6 and 18. In the case of a container 1 having a fifth transfer device, which is used to hold an ophthalmic solution, an application for delivering a drop of about 20 to 40 // L (ml) of liquid for each transfer operation The outer diameter of the valve element supporting member 94a is set in the range of 0. 6 to 2.0 mm, and preferably in the range of 1. to i. The thickness of the thin portion 93a of the valve member 93 is set in the range of 0.8 to 2.5 mm, and preferably in the range of 〇·8 to ι·5. In order to prevent liquid from leaking out of the outlet hole 92, the thin portion 93a of the valve member is preferably more or less inflated by the valve member supporting member 94a. Therefore, the inner diameter of the -39-1294396 (37) in which the non-valve member g-support member 94a is inserted through the thin-walled portion 93a is preferably slightly smaller than the outer diameter of the valve member supporting member 94a. For example, the inner diameter of the thin portion 93a is preferably adjusted to the range of 50 to 99% of the outer diameter of the valve element supporting member 94a, and preferably to the range of 60 to 80%. In the conveying device 90 shown in Fig. 39, the closing of the flow path 95 is not only by the contact of the thin portion 93a and the valve element supporting member 94a but also by the valve body 93b' and the flange 94b. This is achieved by contact, and the greater effect of preventing liquid from leaking out of the outlet hole 92 is achieved. Therefore, the inner diameter of the thin portion 9 3 a can be explained by fewer necessary conditions than the above examples. The conveying device of the present invention and the components of the container provided with the same will be described in detail below. (Valve Element) The valve element in the conveying device of the present invention must satisfy the following conditions, in which compression or expansion deformation is easily achieved by the pressure of the liquid applied from the side of the container body, which is lower than the liquid passing through the air filter. The required pressure, and the compression or expansion deformation cannot be achieved by the air pressure required for the air to pass through the air filter from the outside. A material which can be used for a valve member including a thermoplastic elastomer having a low hardness; a gel-like material; and a rubber such as natural rubber, silicone rubber, isoprene rubber, butyl rubber, butadiene rubber, and fluorinated rubber. Although there is no limitation on the type of material, in order to have the above characteristics regarding swelling deformation or compression deformation, the hardness of the valve member is based on the jIS A hardness (according to the specified JIS Κ 63 0 1 -5·2 to spring hardness test method) The measured spring hardness Hs (type Α) is 〇 to the range of 40. The hardness (JIS A ) of the valve member is preferably not higher than 30, more preferably within 20, and most preferably within 1 Torr, in the above-mentioned range of -40 - 1294396 (38). Although the lower limit of the hardness (JIS A ) of the valve element is not further limited than the range including the above, depending on the material usability, the valve element, and other factors, in the case of JIS A, the 値 can be 2 or higher. Specific examples of the material of the valve element include the following. Examples of thermoplastic elastomers include modified SEBS copolymers such as SEBS, SBS, SIS, and modified marolin; styrene elastomers such as SEPS, SEB, and SEP; hydroxyl elastic properties such as styrene-propylene block copolymers Body; polyurethane elastomer; and mixtures thereof. Among the thermoplastic styrene elastomers, "Septone" compounds manufactured by KURARAY PLASTICS CO., LTD. are preferred. Examples of the gel-like material include a colloid containing a linear hydrocarbon polymer (hydroxy elastomer) (for example, "Cosmo-gel" manufactured by Cosmo Instrument Co., Ltd.); and a ruthenium-urethane colloid (by "Chemitekgel (registered name)" manufactured by chemitek Co.). The elastic material forming the valve member may be a foamed material (the voids are separated from each other so as not to permeate into the liquid, or may be a material whose hardness is adjusted within the above range by the additive). In addition to the hardness, the ability of the valve member to deform under liquid pressure can also be measured by the tensile strength and coefficient of the compressive elasticity of the elastic material. The elastic material forming the valve member preferably has a permanent strain ratio cs of not higher than 50 (at 70 ° C for 22 hours according to JIS K73 0 1 ), so that after repeated cycles of loading and unloading with this liquid pressure Will not break -41 - (39) 1294396 In the case where the conveyor is used outside the eye dropper, consider the drop rate of the ophthalmic solution is usually about 0.05 mL / sec, so that the valve element is p-compressed or swollen. The pressure required is preferably from 0.01 to 0.2 M a.

A. When the valve elements 33, 33' are fixed to the inner surface (3) of the outlet portion 31 on the conveying means 30, 30 as shown in Figs. 9 and 18, the conveying means 30, 30' and the outlet body 3 are provided. 1 a may be integrally formed by selecting a plastic material from the elastic materials listed above. The valve element is attached to the outlet opening 7 of the outlet portion body 71a. As an example of the conveyor 70 shown, the valve element 73 and the outlet portion 71a are selected from thermoplastic materials in the elastomeric materials listed above. Formed as a whole. The valve element is disposed in the outlet portion 71' by being inserted between the outlet portion body 71a' and the tubular body 74a, and the tubular body 74a is provided to be combined with the valve member as shown in the conveying device 70' shown in Fig. 32. The material forming the valve element is not limited to the thermoplastic material. (Air Filter) The air filter used in the present invention must pass the liquid at a pressure higher than the pressure at which the valve member of the conveyor is compressed and expanded, and the pressure required to allow the air to pass from the outside is lower than the opening. The force of the exit hole. Since the pressure of the liquid containing the conveying device is compressed and expanded to change depending on the speed of the conveying operation (the dropping speed of the delivered droplets), the liquid passing pressure of the air filter and the air passing pressure must be transmitted according to the pressure. The application rate of the device and the expected speed of the transfer operation are set to line 1 e. The pressure of the knot can also be -42- (40) 1294396 The drop rate of the ophthalmic solution is usually 0.05 mL / sec. A pressure of 0.01 to 0.2 Mp a is required to cause the valve unit to undergo compression or/expansion deformation, thus dropping the ophthalmic solution. Therefore, it is assumed that the conveying device is used for the eye drop device. When the ophthalmic solution is dripped, the liquid passing pressure of the air filter of 0.01 Mp a or higher, preferably 0.2 Mpa or more, makes it possible to Prevent the ophthalmic solution from leaking through the through holes. After the ophthalmic solution is instilled, the speed of the air-filled compressed eyedropper (air inlet velocity) is usually 1 to 10 mL / sec. An air filter having an air pressure of less than 0.005 MPa, preferably 0.001 Mp, can achieve smooth entry of outside air through the through hole. The mesh size of the air filter is determined such that only air passes, but blocks the liquid delivered by the transfer device of the present invention (the liquid contained in the container of the present invention), microorganisms such as bacteria, and floats by the air. Dust, and the mesh size is usually set in the range of 0.1 to 0.45 β m. The air filter which can be used in the present invention includes, but is not limited to, a hydrophobic P T F E film manufactured by GORE-TEX JAPAN IN C, and a hydrophobic Durapore (PVDF) manufactured by Nihon Millipore Corporation. (Liquid filter) The liquid filter used in the present invention allows a liquid to pass when the applied pressure is lower than a specific level. When such a liquid filter is installed upstream of the outlet port, if the residual liquid remaining near the outlet hole is returned upstream, -43-(41) 1294396 it is possible to prevent residual liquid from entering the container connected to the transfer device . The liquid filter which can be used in the present invention includes, but is not limited to, a hydrophobic P T F E film manufactured by GORE-TEX JAPAN IN C., and a hydrophobic Durapore (PVDF) and a hydrophobic PES manufactured by Nihon Millipore Corporation. (Cover) In the conveying device of the present invention, in addition to the outlet opening, the antibacterial treatment may be applied to the cover covering the outer surface of the outlet portion. The portion of the lid to which the antibacterial treatment is applied is, but not limited to, a portion whose inner surface is in contact with the outlet hole, and a sponge provided in the lid. Since the liquid is returned from the outlet port to the upstream without the transfer device of the present invention, after the liquid transfer operation is completed, the residual liquid remaining remains in the vicinity of the exit hole without returning to the outlet portion. Therefore, by using a cap provided with a water-absorbent material, and after the liquid transfer operation is completed, the residual liquid remaining in the vicinity of the exit hole is sucked by the sponge, and the supply of the residual liquid can be prevented at the next liquid transfer operation (refer to the figure). 17 and Figure 27). When the antibacterial treatment is applied to the sponge in contact with the exit hole, the antibacterial agent can be filtered from the sponge and accumulated on the exit hole. To avoid this problem, such a design can be utilized because the residual liquid extruded from the inner surface of the lid is also absorbed by the water absorbing material provided around the inner surface of the lid (see Figure 35). For example, a sponge made of a material such as urethane or foamed -44-(42) 1294396 polyurethane; a cloth made of non-woven fabric, absorbent cotton or gauze; paper or an aqueous colloid. The sponge can be made from materials of urethane or foamed polyurethane which are well known in the art. The antibacterial treatment of the sponge is preferably applied to the surface of the sponge on which the antibacterial agent has been formed, or the antibacterial agent is mixed into the material of the urethane or foamed polyurethane prior to forming the sponge. . Further, a water-absorbent material having an antibacterial action can be used. Antibacterial treatment applied to cloth, paper, aqueous colloids, and the like includes, for example, decane coupling and selenium coating. Examples of the water-based colloid include a mixture of a acrylamide polymer and a water-swellable clay mineral (see Japanese Laid-Open Patent Application No. 2002-5 3 629 and Japanese Laid-Open Patent Application No. 2002-53762). The material of the device, the lid and the container body) The conveying device, the lid and the container body can be made of a resin material such as PE or PP. In particular, PE and PP can be safely used in the application of a medicament, and preferably, a container containing a liquid medicine such as an ophthalmic solution of the present invention. The resin material used to form the conveying device, the lid and the container body may be previously mixed with a disinfectant or an antibacterial agent, and after the liquid transfer operation is completed, the effect of preventing the residual liquid from remaining in the vicinity of the outlet hole and the effect of degrading the liquid in the container can be enhanced. . For example, "Dimer 38" manufactured by Inui Corporation and the fourth grade ammonium salt of "Dimer 136" can be used as a disinfectant 1-45- 1294396 (43). The transfer device, lid and container body can also be formed after formation. Applying with a disinfectant' or, when forming a conveyor, a cover, and a container body, applying a surface treatment such as sand chamber coupling. The lipid-containing material having an antibacterial effect can be used to form an alpha portion, etc. The conveying device of the present invention can achieve the conveying operation, and the smooth recovery of the glutinous body after the conveying operation, and at the same time, at a high level, the backflow of the liquid that has been delivered from the outlet hole, and the microorganisms in the liquid and The dust enters the upstream. In the conveying device of the present invention, since the deformation of the valve member is achieved at a pressure lower than the pressure of the air filter, the transfer through the outlet hole can be reliably achieved without occurring during the conveying operation. The leakage of the liquid. Furthermore, because the opening of the outlet hole and/or the flow path communicating with the outlet hole, the air from the outside is not passed through the air filter. The force is achieved that this problem does not occur when the outer boundary air enters through the exit hole of the replacement through hole during the recovery of the container body. Therefore, the transfer device of the present invention can achieve the transfer operation and after the transfer operation 'The smooth recovery of the container body, at the same time, at a high level, prevents the backflow of the liquid that has been delivered from the outlet hole, and the microorganisms and dust in the liquid enter the upstream. The conveying device of the present invention does not utilize the Japanese patent application filed according to the Japanese patent application. The porous filter disposed at the outlet portion of the Japanese Patent Application No. 200 1 -206454 and the Japanese Laid-Open Patent Application No. 2 00 1 - 790 1 7 even when the liquid contained in the 46-(44) 1294396 is a suspension The possibility of blockage of the exit hole is very low. Depending on the size and material of the valve element and the exit hole, 'If the size of the suspension particles is about 50 // m or less, the exit hole will not block. The container of the invention causes the conveying device of the present invention to be installed at its mouth. Therefore, the backflow of the liquid which has been discharged from the outlet hole can be prevented at a high level, and in the liquid Microorganisms and dust enter the upstream. Therefore, in order to prevent degradation and deterioration of the liquid, it is possible to remove or reduce the use of the disinfectant. Moreover, since the container of the present invention does not utilize the porous filter provided in its outlet hole, the outlet hole will It does not block, and therefore, even when the liquid contained is a suspension, smooth transfer of the liquid can be achieved, except that the liquid filter is disposed upstream of the transfer device. The transfer device of the present invention is also preferred. The ground has a plug slidably held in the flow path or container body of the conveyor so that the plug can come into contact with the inner wall of the flow path of the conveyor and, when the container is not in use, close the flow path. Make sure that the liquid contained is kept in a sterile configuration in a sterile state until the container is used. Moreover, because the liquid can be kept in contact with the valve element and the air filter before use, the stable quality can be maintained for a long time. The container of the present invention is suitable for use as an eye drop device containing an ophthalmic solution. BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 is a cross-sectional view showing an embodiment of a first conveying device. The B 2 series shows a cross-sectional view of an embodiment of a container provided with a first transfer device. -47- (45) 1294396 Fig. 3 is a cross-sectional view showing the state of the container shown in Fig. 2 before being sealed. Figure 4 is a cross-sectional view showing the state of the container shown in Figure 2 in use. Fig. 5 is a cross-sectional view showing a state following the state shown in Fig. 4. Figure 6 is a cross-sectional view showing another embodiment of a container provided with a first transfer device. Figure 7 is a cross-sectional view showing another embodiment of the first transfer device. Figure 8 is a cross-sectional view showing another embodiment of the first transfer device. Figure 9 is a cross-sectional view showing an embodiment of a second conveyor. Fig. 1 is an exploded cross-sectional view showing the conveying device 30 shown in Fig. 9. Fig. 11 (a) is a plan view showing an example in which the outlet portion body 31a and the valve member 33 are integrally formed, and Fig. 11 (b) is a bottom view thereof. Figure 12 (a) is a plan view of the valve seat portion 34, and Figure 12 (b) is a bottom view thereof. Fig. 13 (a) is a plan view showing another example in which the outlet body and the valve member are integrally formed; and Fig. 13 (b) is a plan view showing another example of the valve seat portion. Figure 14 is a cross-sectional view showing an embodiment of a container provided with a second transfer device. Figure 15 is a cross-sectional view showing the state of the container of Figure 14 in use. Fig. 16 shows a cross-sectional view of the state shown in Fig. 15. Figure 17 is a cross-sectional view showing the container 40 shown in Figure 14 in an unsealed state. Figure 18 is a cross-sectional view showing another embodiment of the second transfer device. -48- 1294396 (46) Figure 19 is a cross-sectional view showing an embodiment of a third conveying device. Figure 20 is an exploded cross-sectional view of the conveyor 50 shown in Figure 19. Figure 21 is a plan view showing the outlet portion body 51a shown in Figure 20 . Fig. 22 (a) is a plan view of the valve element supporting member 54 shown in Fig. 20, and Fig. 22 (b) is a bottom view thereof. Fig. 23 is a view showing a procedure for assembling the conveying device 50 shown in Fig. 19. Figure 24 is a cross-sectional view showing an example of a container provided with the conveying device 50 shown in Figure 19. Figure 25 is a cross-sectional view showing the state of the container 60 shown in Figure 24 in use. Fig. 26 is a cross-sectional view showing a state following the state shown in Fig. 25. Figure 27 is a cross-sectional view showing the container 60 shown in Figure 24 in an unsealed state. Figure 28 is a cross-sectional view showing an embodiment of a fourth conveying device. Fig. 29 (a) is a bottom view of the conveying device 70 shown in Fig. 28, and Fig. 29 (b) is a sectional view taken along line A-A. Figure 30 (a) is a cross-sectional view showing an example of a container provided with a fourth transfer device 70, and Figure 30 (b) is a cross-sectional view showing a state in which it is used. Figure 3 1 shows a view subsequent to Figure 3 0 (b) A cross-sectional view of the state of the state shown. Figure 32 is a cross-sectional view showing another embodiment of the fourth transfer device. Figure 33 is a cross-sectional view showing an embodiment of a fifth conveying device. -49- 1294396 (47) Figure 34 is a cross-sectional view showing an embodiment of a container provided with a fifth conveying means. Figure 35 (a) is a cross-sectional view showing the container 100 with a lid shown in Figure 34, and Figure 35 (b) is a cross-sectional view of the lid. Figure 36 is a cross-sectional view showing the state of the container of Figure 34 in use. Fig. 37 is a cross-sectional view showing a state following the state shown in Fig. 36. Fig. 38 is an enlarged cross-sectional view showing the outlet portion of the container 1A shown in Fig. 36 (b). Figure 39 is a cross-sectional view showing another embodiment of the fifth conveying device. Figure 40 is an enlarged cross-sectional view showing the outlet portion of the container 100' shown in Figure 39 in use. Fig. 4 1 (a) is a front view showing an example of a conventional eye drop device, and Fig. 41 (b) is an enlarged sectional view of the conveying device. Fig. 42 is a schematic view showing the problem of the eye drop device of the prior art. & component comparison table 10 JO', 10a, 10b, 30, 30'50, 70, 70, 90, 90, conveyor 1 13151, 71, 71^91 outlet portion 1 Id outlet portion inner surface 12, 32, 52,72,92 outlet holes 13'Ua, 13b, 33, 33'53, 73, 73,, 93, 93, valve element 14 locking member l5, 35, 5 5, 75, 95 flow path 1, 6, 36 ,5 6,76,96 through hole-50 1294396 (48) 1 7,3 7,5 7,77,97 1 8,3 8,5 8,7 8 20,20^40,60,80,1 00 2 1 ?4 1 ?6 1 ,8 1 5 1 0 1 23.43.63.83.1 03 24.44.64.84.1 04 25,45,65,8 5,1 05 25,,45,,65,,85,, 105, 26.46.66.1 06 34a, 34a,, 74 52a 52b 53a 53b 93a 93b 94a 94b

U

D Air filter liquid filter container (eye drop) Container body plug contains liquid droplets Residual liquid cover valve seat flow path inner wall ridge valve body convex portion thin wall valve body valve member support member flange upstream side downstream Side-51 -

Claims (1)

1294396 Picking up, applying for patent scope 92 1 207 1 4 Patent application Chinese patent application scope revision Republic of China | 9 6 March month 2S #(筻) Liben 1.--type transmission device, including: L--... ------------- an outlet portion having a substantially bottom tubular or substantially bowl shape having an outlet opening at the bottom thereof; a valve member made of a thermoplastic elastomer and disposed in The outlet portion closes the outlet hole when no liquid pressure is applied thereto from the upstream side, and when a liquid pressure is applied thereto from the upstream side, undergoes compression deformation and opens the outlet hole, a side of the outlet hole is defined as a downstream; a locking member disposed at the outlet portion to define a flow path between itself and the inner surface of the outlet portion, and fixing the valve member upstream; and a venting hole through an air a filter is connected to the outlet hole, the outlet hole is disposed at a position upstream of the valve element, wherein the compression deformation of the valve element is achieved by a liquid pressure lower than a liquid passing through the air filter by a pressure, and Outlet hole and / or flow It can not open from the outside air by the air filter to be achieved by the pressure. 2. The transfer device of claim 1, wherein the valve member and the locking member are integrally formed. 3. A conveying device comprising: an outlet portion having a substantially bottom tubular or substantially bowl shape having an outlet opening at a bottom thereof; 1294396 a valve seat fixed to the outlet portion; a valve member for thermoplasticizing The elastic body is formed into a substantially tubular shape, and the valve element is fixed on the inner surface of the outlet portion, and when no liquid pressure is applied thereto, the valve seat is contacted from the downstream side to close the flow path communicating with the outlet hole, and Compressively deforming to open a flow path between itself and the valve seat when liquid pressure is applied from the upstream side, the outlet hole side being defined as a downstream; and a venting hole through an air filter The outlet hole is communicated, and the outlet hole is disposed at a position upstream of the valve element, wherein the compression deformation of the valve element is achieved by a liquid pressure lower than a liquid passing through the air filter, and the outlet hole and/or Or the opening of the flow path cannot be achieved from the outside by the air passing pressure of the air filter. 4. The transfer device of claim 3, wherein the valve element and the outlet portion are integrally formed. 5. A conveying device comprising: an outlet portion having a substantially bottom tubular or substantially bowl shape having an outlet opening at a bottom thereof; a valve member formed of a thermoplastic elastomer having a substantially annular valve a body and a substantially annular thin-walled portion are provided at an end of the former, the valve system is fixed to the outlet portion, but the thin-walled portion is exposed through the hole to the outside of the outlet portion; a cylindrical valve element supporting member is disposed at The outlet portion defines an outlet hole and the valve member; and a vent hole communicates with the outlet hole via an air filter, and the outlet port - 2294396 is disposed at an upstream position of the valve member, and the outlet hole side Described as downstream, wherein the valve element has its thin-walled portion in contact with the outer circumference of the valve element supporting member to close the outlet hole when no liquid pressure is applied thereto from the upstream side, but the thin-walled portion is expanded and deformed So that the outlet hole is opened when the liquid pressure is applied thereto, and the expansion deformation of the thin portion is achieved by the liquid pressure of the liquid passing the pressure lower than the air filter. , Opens the outlet orifice of the can from the outside air by an air filter to be reached by the pressure. [6] The transfer device of claim 5, wherein the valve element support member has a position in which the flange is located on the upstream side of the circular portion, but the valve body of the valve member is in contact with the flange so that The flow path is closed when no liquid pressure is applied thereto from the upstream side, and compression deformation is performed to open the flow between itself and the valve element supporting member when the liquid pressure is applied thereto from the upstream side. road. 7. The transfer device of claim 5, wherein the valve member and the outlet portion are integrally formed. 8. The transfer device of claim 6, wherein the valve element and the outlet portion are integrally formed. The transfer device of any one of claims 1 to 8, wherein an antibacterial treatment has been applied to the valve member. The conveying device of any one of claims 1 to 8, wherein an antibacterial treatment has been applied to the outlet opening. 1 1 - The conveyor 3 - 1294396 of any one of claims 1 to 8, wherein a liquid filter is disposed upstream of the outlet opening or is opened and closed by the valve element The upstream of the location of the road. 1 2. A container having a transfer device according to any one of claims 1 to 11 which is assembled in a mouth of a container body 13. As claimed in claim 12 a container comprising a plug slidably held in the flow path of the conveyor or in the container body, however the plug is in contact with the inner wall of the flow path of the conveyor so that the container is used before it is used, Close the flow path. 14. The container of claim 12 or 13 which is an eye dropper. -4-