KR20040085216A - 알파-２-델타 리간드와 시클로옥시게나제-２의 선택적인억제제의 조합 제제 - Google Patents
알파-２-델타 리간드와 시클로옥시게나제-２의 선택적인억제제의 조합 제제 Download PDFInfo
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- KR20040085216A KR20040085216A KR10-2004-7013032A KR20047013032A KR20040085216A KR 20040085216 A KR20040085216 A KR 20040085216A KR 20047013032 A KR20047013032 A KR 20047013032A KR 20040085216 A KR20040085216 A KR 20040085216A
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- South Korea
- Prior art keywords
- aminomethyl
- acetic acid
- alpha
- methyl
- cyclopentyl
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Neurosurgery (AREA)
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- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35929502P | 2002-02-22 | 2002-02-22 | |
| US60/359,295 | 2002-02-22 | ||
| US40436502P | 2002-08-19 | 2002-08-19 | |
| US60/404,365 | 2002-08-19 | ||
| PCT/IB2003/000534 WO2003070237A1 (en) | 2002-02-22 | 2003-02-12 | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
Publications (1)
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| KR20040085216A true KR20040085216A (ko) | 2004-10-07 |
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| KR10-2004-7013032A Ceased KR20040085216A (ko) | 2002-02-22 | 2003-02-12 | 알파-２-델타 리간드와 시클로옥시게나제-２의 선택적인억제제의 조합 제제 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20030199567A1 (https=) |
| EP (1) | EP1480639A1 (https=) |
| JP (1) | JP2005523281A (https=) |
| KR (1) | KR20040085216A (https=) |
| CN (1) | CN1635887A (https=) |
| AR (1) | AR038531A1 (https=) |
| AU (1) | AU2003246864A1 (https=) |
| BR (1) | BR0307906A (https=) |
| CA (1) | CA2476438A1 (https=) |
| CO (1) | CO5611109A2 (https=) |
| HN (1) | HN2003000071A (https=) |
| IL (1) | IL162932A0 (https=) |
| MX (1) | MXPA04008175A (https=) |
| NO (1) | NO20043947L (https=) |
| PA (1) | PA8567201A1 (https=) |
| PE (1) | PE20031052A1 (https=) |
| PL (1) | PL372210A1 (https=) |
| RU (1) | RU2286151C2 (https=) |
| TW (1) | TW200303214A (https=) |
| UY (1) | UY27675A1 (https=) |
| WO (1) | WO2003070237A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019190118A1 (ko) * | 2018-03-30 | 2019-10-03 | 크리스탈지노믹스(주) | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| RU2789402C1 (ru) * | 2018-03-30 | 2023-02-02 | Кристалдженомикс, Инк. | Фармацевтическая композиция, содержащая полмакоксиб и прегабалин, для лечения боли |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004054560A1 (en) * | 2002-12-13 | 2004-07-01 | Warner-Lambert Company Llc | Alpha-2-delta ligand to treat lower urinary tract symptoms |
| WO2004084880A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | METHODS FOR TREATING PAIN USING SMOOTH MUSCLE MODULATORS AND α2δ SUBUNIT CALCIUM CHANNEL MODULATORS |
| WO2004084881A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | METHODS FOR TREATING FUNCTIONAL BOWEL DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS WITH SMOOTH MUSCLE MODULATORS |
| DE602004003172T2 (de) * | 2003-03-21 | 2007-09-27 | Dynogen Pharmaceuticals Inc., Waltham | Verfahren zur behandlung von erkrankungen der unteren harnwege mit antimuskarinika und mit modulatoren der alpha-2-delta untereinheit des kalziumkanals |
| US7169812B2 (en) * | 2003-07-01 | 2007-01-30 | Medtronic, Inc. | Process for producing injectable gabapentin compositions |
| NZ545494A (en) * | 2003-09-12 | 2009-10-30 | Pfizer | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
| GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| WO2005041976A2 (en) * | 2003-10-23 | 2005-05-12 | Medtronic, Inc. | Injectable gabapentin compositions |
| AR060404A1 (es) * | 2006-04-11 | 2008-06-11 | Novartis Ag | Compuestos organicos utiles como inhibidores de dipeptidil-peptidasa iv |
| US20130012485A1 (en) * | 2006-12-22 | 2013-01-10 | Baeschlin Daniel Kaspar | Organic compounds |
| CA2723358A1 (en) * | 2008-05-05 | 2009-11-12 | Allison B. Reiss | Method for improving cardiovascular risk profile of cox inhibitors |
| SI2735338T1 (sl) * | 2008-09-05 | 2019-04-30 | Grunenthal Gmbh | Farmacevtska kombinacija 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol in pregabalina ali gabapentina |
| JP2023548380A (ja) * | 2020-10-28 | 2023-11-16 | トレモー・ファーマシューティカルズ・インコーポレイテッド | 非水溶性ｃｏｘ－２阻害の水性製剤 |
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| US5234929A (en) * | 1992-07-20 | 1993-08-10 | William Chelen | Method of treating motion sickness with anticonvulsants and antitussive agents |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5352638A (en) * | 1994-02-22 | 1994-10-04 | Corning Incorporated | Nickel aluminosilicate glass-ceramics |
| RU2168982C2 (ru) * | 1994-07-27 | 2001-06-20 | Варнер-Ламберт Компани | Способ лечения состояния страха или лечения и/или предупреждения состояния паники, очищенный белок, способный связывать габапентин, и фармацевтическая композиция, обладающая успокоительным, противопаническим и противосудорожным действием |
| US5633272A (en) * | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
| WO1999008670A1 (en) * | 1997-08-20 | 1999-02-25 | Guglietta, Antonio | Gaba analogs to prevent and treat gastrointestinal damage |
| WO1999012537A1 (en) * | 1997-09-08 | 1999-03-18 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| CA2304967C (en) * | 1997-12-16 | 2005-06-14 | Warner-Lambert Company | 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
| US6451857B1 (en) * | 1999-03-10 | 2002-09-17 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| HN2000000224A (es) * | 1999-10-20 | 2001-04-11 | Warner Lambert Co | Aminoacidos biciclicos como agentes farmaceuticos |
| GB9927844D0 (en) * | 1999-11-26 | 2000-01-26 | Glaxo Group Ltd | Chemical compounds |
| JP2003516353A (ja) * | 1999-12-08 | 2003-05-13 | ファルマシア コーポレイション | ヴァルデコキシブ組成物 |
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- 2003-02-12 JP JP2003569193A patent/JP2005523281A/ja not_active Abandoned
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- 2003-02-12 PL PL03372210A patent/PL372210A1/xx not_active Application Discontinuation
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- 2003-02-12 BR BR0307906-6A patent/BR0307906A/pt not_active IP Right Cessation
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019190118A1 (ko) * | 2018-03-30 | 2019-10-03 | 크리스탈지노믹스(주) | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| RU2789402C1 (ru) * | 2018-03-30 | 2023-02-02 | Кристалдженомикс, Инк. | Фармацевтическая композиция, содержащая полмакоксиб и прегабалин, для лечения боли |
| US11602517B2 (en) | 2018-03-30 | 2023-03-14 | Crystalgenomics, Inc. | Pharmaceutical composition, comprising polmacoxib and pregabalin, for treatment of pain |
Also Published As
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| PE20031052A1 (es) | 2003-12-24 |
| PL372210A1 (en) | 2005-07-11 |
| AR038531A1 (es) | 2005-01-19 |
| MXPA04008175A (es) | 2004-11-26 |
| BR0307906A (pt) | 2004-12-21 |
| EP1480639A1 (en) | 2004-12-01 |
| IL162932A0 (en) | 2005-11-20 |
| CO5611109A2 (es) | 2006-02-28 |
| HN2003000071A (es) | 2003-11-24 |
| AU2003246864A1 (en) | 2003-09-09 |
| CA2476438A1 (en) | 2003-08-28 |
| RU2286151C2 (ru) | 2006-10-27 |
| CN1635887A (zh) | 2005-07-06 |
| PA8567201A1 (es) | 2003-11-12 |
| WO2003070237A1 (en) | 2003-08-28 |
| US20030199567A1 (en) | 2003-10-23 |
| NO20043947L (no) | 2004-09-21 |
| RU2004125609A (ru) | 2006-01-27 |
| UY27675A1 (es) | 2003-09-30 |
| JP2005523281A (ja) | 2005-08-04 |
| TW200303214A (en) | 2003-09-01 |
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