PE20031052A1 - Combinaciones de un ligando alfa-2-delta con un inhibidor selectivo de la cicloxigenasa-2 - Google Patents
Combinaciones de un ligando alfa-2-delta con un inhibidor selectivo de la cicloxigenasa-2Info
- Publication number
- PE20031052A1 PE20031052A1 PE2003000166A PE2003000166A PE20031052A1 PE 20031052 A1 PE20031052 A1 PE 20031052A1 PE 2003000166 A PE2003000166 A PE 2003000166A PE 2003000166 A PE2003000166 A PE 2003000166A PE 20031052 A1 PE20031052 A1 PE 20031052A1
- Authority
- PE
- Peru
- Prior art keywords
- alpha
- cycloxygenase
- combinations
- selective inhibitor
- delta ligand
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
SE REFIERE A UNA COMPOSICION QUE COMPRENDE: a) VALDECOXIB O UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES Y b) UN LIGANDO ALFA-2-DELTA SELECCIONADO DE GABAPENTINA, PREGABALINA, HIDROCLORURO DE 3-(1-AMINOMETIL-CICLOHEXILMETIL)-4H-[1,2,4]-OXADIAZOL-5-ONA, (3S,4S)-(1-AMINOMETIL-3,4-DIMETIL-CICLOPENTIL)-ACETICO. LA COMPOSICION COMPRENDE ADEMAS UN VEHICULO, DILUYENTE FARMACEUTICAMENTE ACEPTABLE Y ES UTIL PARA EL TRATAMIENTO DE INFLAMACION, OSTEOARTRITIS, ARTRITIS REUMATOIDE
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35929502P | 2002-02-22 | 2002-02-22 | |
| US40436502P | 2002-08-19 | 2002-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20031052A1 true PE20031052A1 (es) | 2003-12-24 |
Family
ID=27760521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003000166A PE20031052A1 (es) | 2002-02-22 | 2003-02-17 | Combinaciones de un ligando alfa-2-delta con un inhibidor selectivo de la cicloxigenasa-2 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20030199567A1 (es) |
| EP (1) | EP1480639A1 (es) |
| JP (1) | JP2005523281A (es) |
| KR (1) | KR20040085216A (es) |
| CN (1) | CN1635887A (es) |
| AR (1) | AR038531A1 (es) |
| AU (1) | AU2003246864A1 (es) |
| BR (1) | BR0307906A (es) |
| CA (1) | CA2476438A1 (es) |
| CO (1) | CO5611109A2 (es) |
| HN (1) | HN2003000071A (es) |
| IL (1) | IL162932A0 (es) |
| MX (1) | MXPA04008175A (es) |
| NO (1) | NO20043947L (es) |
| PA (1) | PA8567201A1 (es) |
| PE (1) | PE20031052A1 (es) |
| PL (1) | PL372210A1 (es) |
| RU (1) | RU2286151C2 (es) |
| TW (1) | TW200303214A (es) |
| UY (1) | UY27675A1 (es) |
| WO (1) | WO2003070237A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2509605C (en) * | 2002-12-13 | 2010-10-05 | Warner-Lambert Company Llc | Alpha-2-delta ligand to treat lower urinary tract symptoms |
| ES2275229T3 (es) * | 2003-03-21 | 2007-06-01 | Dynogen Pharmaceuticals, Inc. | Metodos para el tratamiento de desordenes del tracto urinario iferior utilizando antimuscarinos y moduladores de la subunidad alfa-2-delta del canal de calcio. |
| WO2004084880A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | METHODS FOR TREATING PAIN USING SMOOTH MUSCLE MODULATORS AND α2δ SUBUNIT CALCIUM CHANNEL MODULATORS |
| WO2004084881A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | METHODS FOR TREATING FUNCTIONAL BOWEL DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS WITH SMOOTH MUSCLE MODULATORS |
| US7169812B2 (en) * | 2003-07-01 | 2007-01-30 | Medtronic, Inc. | Process for producing injectable gabapentin compositions |
| ATE449633T1 (de) * | 2003-09-12 | 2009-12-15 | Pfizer | Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern |
| GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| EP1682149B1 (en) * | 2003-10-23 | 2009-12-02 | Medtronic, Inc. | Injectable gabapentin compositions |
| JP2009533368A (ja) * | 2006-04-11 | 2009-09-17 | ノバルティス アクチエンゲゼルシャフト | 有機化合物 |
| JP2010513357A (ja) * | 2006-12-22 | 2010-04-30 | ノバルティス アーゲー | Ｄｐｐ−ｉｖ阻害剤としての１−アミノメチル−１−フェニル−シクロヘキサン誘導体 |
| US20090275529A1 (en) * | 2008-05-05 | 2009-11-05 | Reiss Allison B | Method for improving cardiovascular risk profile of cox inhibitors |
| KR101641519B1 (ko) * | 2008-09-05 | 2016-07-21 | 그뤼넨탈 게엠베하 | 3-（3-디메틸아미노-1-에틸-2-메틸-프로필）-페놀과 항간질제의 약제학적 병용물 |
| KR102631399B1 (ko) | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| WO2022093978A1 (en) * | 2020-10-28 | 2022-05-05 | Tremeau Pharmaceuticals, Inc. | Aqueous formulations of water insoluble cox-2 inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234929A (en) * | 1992-07-20 | 1993-08-10 | William Chelen | Method of treating motion sickness with anticonvulsants and antitussive agents |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5352638A (en) * | 1994-02-22 | 1994-10-04 | Corning Incorporated | Nickel aluminosilicate glass-ceramics |
| US5633272A (en) * | 1995-02-13 | 1997-05-27 | Talley; John J. | Substituted isoxazoles for the treatment of inflammation |
| WO1999008670A1 (en) * | 1997-08-20 | 1999-02-25 | Guglietta, Antonio | Gaba analogs to prevent and treat gastrointestinal damage |
| EP1011658B1 (en) * | 1997-09-08 | 2005-12-07 | Warner-Lambert Company Llc | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| PL341231A1 (en) * | 1997-12-16 | 2001-03-26 | Warner Lambert Co | 4(3)-substitute derivatives of 4(3)aminomethyl(thio)pyrane or piperidine derivatives (analogues of garbapentin), their production and application in treating neurological disorders |
| WO2000053225A1 (en) * | 1999-03-10 | 2000-09-14 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| HN2000000224A (es) * | 1999-10-20 | 2001-04-11 | Warner Lambert Co | Aminoacidos biciclicos como agentes farmaceuticos |
| GB9927844D0 (en) * | 1999-11-26 | 2000-01-26 | Glaxo Group Ltd | Chemical compounds |
| CN1679556A (zh) * | 1999-12-08 | 2005-10-12 | 法马西亚公司 | 维得克西组合物 |
-
2003
- 2003-02-12 CA CA002476438A patent/CA2476438A1/en not_active Abandoned
- 2003-02-12 PL PL03372210A patent/PL372210A1/xx not_active Application Discontinuation
- 2003-02-12 EP EP03742460A patent/EP1480639A1/en not_active Withdrawn
- 2003-02-12 RU RU2004125609/15A patent/RU2286151C2/ru not_active IP Right Cessation
- 2003-02-12 JP JP2003569193A patent/JP2005523281A/ja not_active Abandoned
- 2003-02-12 AU AU2003246864A patent/AU2003246864A1/en not_active Abandoned
- 2003-02-12 KR KR10-2004-7013032A patent/KR20040085216A/ko not_active Application Discontinuation
- 2003-02-12 CN CNA038043564A patent/CN1635887A/zh active Pending
- 2003-02-12 MX MXPA04008175A patent/MXPA04008175A/es unknown
- 2003-02-12 IL IL16293203A patent/IL162932A0/xx unknown
- 2003-02-12 BR BR0307906-6A patent/BR0307906A/pt not_active IP Right Cessation
- 2003-02-12 WO PCT/IB2003/000534 patent/WO2003070237A1/en not_active Application Discontinuation
- 2003-02-14 US US10/366,798 patent/US20030199567A1/en not_active Abandoned
- 2003-02-17 PE PE2003000166A patent/PE20031052A1/es not_active Application Discontinuation
- 2003-02-19 UY UY27675A patent/UY27675A1/es not_active Application Discontinuation
- 2003-02-20 AR ARP030100547A patent/AR038531A1/es unknown
- 2003-02-21 TW TW092103596A patent/TW200303214A/zh unknown
- 2003-02-21 HN HN2003000071A patent/HN2003000071A/es unknown
- 2003-02-21 PA PA20038567201A patent/PA8567201A1/es unknown
-
2004
- 2004-08-13 CO CO04079024A patent/CO5611109A2/es not_active Application Discontinuation
- 2004-09-21 NO NO20043947A patent/NO20043947L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200303214A (en) | 2003-09-01 |
| WO2003070237A1 (en) | 2003-08-28 |
| CN1635887A (zh) | 2005-07-06 |
| BR0307906A (pt) | 2004-12-21 |
| NO20043947L (no) | 2004-09-21 |
| UY27675A1 (es) | 2003-09-30 |
| EP1480639A1 (en) | 2004-12-01 |
| HN2003000071A (es) | 2003-11-24 |
| CA2476438A1 (en) | 2003-08-28 |
| AU2003246864A1 (en) | 2003-09-09 |
| AR038531A1 (es) | 2005-01-19 |
| KR20040085216A (ko) | 2004-10-07 |
| CO5611109A2 (es) | 2006-02-28 |
| PA8567201A1 (es) | 2003-11-12 |
| IL162932A0 (en) | 2005-11-20 |
| MXPA04008175A (es) | 2004-11-26 |
| RU2286151C2 (ru) | 2006-10-27 |
| JP2005523281A (ja) | 2005-08-04 |
| US20030199567A1 (en) | 2003-10-23 |
| RU2004125609A (ru) | 2006-01-27 |
| PL372210A1 (en) | 2005-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |