KR20040007617A - 부갑상선 호르몬 및 칼시토닌의 경구 투여 - Google Patents
부갑상선 호르몬 및 칼시토닌의 경구 투여 Download PDFInfo
- Publication number
- KR20040007617A KR20040007617A KR10-2003-7015524A KR20037015524A KR20040007617A KR 20040007617 A KR20040007617 A KR 20040007617A KR 20037015524 A KR20037015524 A KR 20037015524A KR 20040007617 A KR20040007617 A KR 20040007617A
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- KR
- South Korea
- Prior art keywords
- pth
- calcitonin
- effective amount
- administration
- oral administration
- Prior art date
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- Ceased
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
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- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US29516901P | 2001-06-01 | 2001-06-01 | |
| US60/295,169 | 2001-06-01 | ||
| PCT/EP2002/006017 WO2002098453A2 (en) | 2001-06-01 | 2002-05-31 | Orally administering parathyroid hormone and calcitonin |
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| KR1020097022621A Withdrawn KR20090116836A (ko) | 2001-06-01 | 2002-05-31 | 부갑상선 호르몬 및 칼시토닌의 경구 투여 |
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| SK (1) | SK287697B6 (enExample) |
| WO (1) | WO2002098453A2 (enExample) |
| ZA (1) | ZA200308625B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101432313B1 (ko) * | 2005-11-17 | 2014-08-20 | 노파르티스 아게 | 약제학적 조성물 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5073153B2 (ja) | 2001-06-01 | 2012-11-14 | ノバルティス アーゲー | 副甲状腺ホルモンおよびカルシトニンの経口投与 |
| BRPI0211932B1 (pt) * | 2001-08-17 | 2016-12-06 | Novartis Ag | composição farmacêutica na forma de dosagem sólida para liberação oral, e uso de sal dissódio de ácido n-(5-cloro-saliciloil)-8-aminocaprílico (5-cnac) |
| US20050054557A1 (en) * | 2002-05-09 | 2005-03-10 | Goldberg Michael M. | Compositions for delivering parathyroid hormone and calcitonin |
| KR20080049128A (ko) | 2005-09-19 | 2008-06-03 | 에미스페어 테크놀로지스, 인코포레이티드 | Ｎ-(5-클로로살리실로일)-8-아미노카프릴산 이나트륨염의결정형 |
| GB0522566D0 (en) * | 2005-11-04 | 2005-12-14 | Novartis Ag | Organic compounds |
| CN101355959B (zh) * | 2005-11-10 | 2013-02-27 | 密歇根理工大学管理委员会 | 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法 |
| PL2215047T3 (pl) | 2007-11-02 | 2014-05-30 | Emisphere Tech Inc | Sposób leczenia niedoborów witaminy b12 |
| CN104857505A (zh) * | 2008-08-18 | 2015-08-26 | 安特拉贝欧有限公司 | 用于口服给予蛋白质的方法和组合物 |
| CA2734442C (en) | 2008-08-18 | 2016-08-16 | Oramed Ltd | Methods and compositions for oral administration of proteins |
| WO2011071480A1 (en) | 2009-12-07 | 2011-06-16 | Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
| WO2012130193A1 (en) | 2011-03-31 | 2012-10-04 | Zentiva, K.S. | Non-covalent soluble complexes of teriparatide with polysaccharides and a dosage form of teriparatide for oral administration |
| CN104800564A (zh) * | 2015-04-02 | 2015-07-29 | 中国人民解放军济南军区总医院 | 一种治疗血虚不荣型甲状旁腺功能减退症的中药组合物 |
| KR101796604B1 (ko) * | 2016-08-30 | 2017-11-10 | 목포대학교 산학협력단 | 위장관 흡수증진제를 함유하는 부갑상선 호르몬의 경구 투여 제형 |
| KR102163445B1 (ko) | 2017-11-20 | 2020-10-07 | 주식회사 노브메타파마 | Chp(사이클로-히스프로)를 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물 |
| KR102115353B1 (ko) * | 2019-05-17 | 2020-05-26 | 주식회사 노브메타파마 | Chp(사이클로-히스프로) 및 부갑상선 호르몬을 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692433A (en) * | 1983-10-12 | 1987-09-08 | The Regents Of The University Of California | Method and composition for regulating serum calcium levels of mammals |
| US5364840A (en) * | 1989-12-05 | 1994-11-15 | Vical, Inc. | Synthetic calcitonin peptides |
| US5118667A (en) * | 1991-05-03 | 1992-06-02 | Celtrix Pharmaceuticals, Inc. | Bone growth factors and inhibitors of bone resorption for promoting bone formation |
| AU6268894A (en) * | 1993-02-22 | 1994-09-14 | Alza Corporation | Compositions for oral delivery of active agents |
| US5866536A (en) * | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5650386A (en) | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
| US5723577A (en) | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
| US5955574A (en) * | 1995-07-13 | 1999-09-21 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. | Analogs of parathyroid hormone |
| CA2319672C (en) | 1997-02-07 | 2011-01-04 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
| SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| DE19915272A1 (de) * | 1999-04-03 | 2000-10-05 | Vetter & Co Apotheker | Spritze für medizinische Zwecke |
| WO2000059863A1 (en) * | 1999-04-05 | 2000-10-12 | Emisphere Technologies, Inc. | Disodium salts, monohydrates, and ethanol solvates |
| WO2001032201A2 (en) | 1999-10-29 | 2001-05-10 | Eli Lilly And Company | A pharmaceutical composition having high cell membrane permeability |
| US7049283B2 (en) * | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
| JP5073153B2 (ja) | 2001-06-01 | 2012-11-14 | ノバルティス アーゲー | 副甲状腺ホルモンおよびカルシトニンの経口投与 |
| BRPI0211932B1 (pt) * | 2001-08-17 | 2016-12-06 | Novartis Ag | composição farmacêutica na forma de dosagem sólida para liberação oral, e uso de sal dissódio de ácido n-(5-cloro-saliciloil)-8-aminocaprílico (5-cnac) |
| US7318925B2 (en) * | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
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2002
- 2002-05-31 JP JP2003501491A patent/JP5073153B2/ja not_active Expired - Fee Related
- 2002-05-31 CN CNA028111613A patent/CN1512892A/zh active Pending
- 2002-05-31 KR KR10-2003-7015524A patent/KR20040007617A/ko not_active Ceased
- 2002-05-31 DE DE60218842T patent/DE60218842T2/de not_active Expired - Lifetime
- 2002-05-31 NZ NZ529439A patent/NZ529439A/en not_active IP Right Cessation
- 2002-05-31 BR BRPI0209748A patent/BRPI0209748B1/pt not_active IP Right Cessation
- 2002-05-31 HU HU0400120A patent/HU229613B1/hu not_active IP Right Cessation
- 2002-05-31 ES ES02750997T patent/ES2282436T3/es not_active Expired - Lifetime
- 2002-05-31 US US10/478,631 patent/US20040186050A1/en not_active Abandoned
- 2002-05-31 KR KR1020097022621A patent/KR20090116836A/ko not_active Withdrawn
- 2002-05-31 WO PCT/EP2002/006017 patent/WO2002098453A2/en not_active Ceased
- 2002-05-31 CZ CZ2003-3232A patent/CZ307145B6/cs not_active IP Right Cessation
- 2002-05-31 AU AU2002344371A patent/AU2002344371B2/en not_active Ceased
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- 2002-05-31 PL PL364089A patent/PL211976B1/pl unknown
- 2002-05-31 KR KR1020127010903A patent/KR101320817B1/ko not_active Expired - Fee Related
- 2002-05-31 PT PT02750997T patent/PT1397156E/pt unknown
- 2002-05-31 IL IL15877702A patent/IL158777A0/xx unknown
- 2002-05-31 CA CA2446929A patent/CA2446929C/en not_active Expired - Fee Related
- 2002-05-31 SK SK1475-2003A patent/SK287697B6/sk not_active IP Right Cessation
- 2002-05-31 MX MXPA03011027A patent/MXPA03011027A/es active IP Right Grant
- 2002-05-31 CN CN200910258008A patent/CN101837120A/zh active Pending
- 2002-05-31 EP EP02750997A patent/EP1397156B1/en not_active Expired - Lifetime
- 2002-05-31 RU RU2003136733/15A patent/RU2300392C2/ru not_active IP Right Cessation
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2003
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2006
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2008
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2010
- 2010-04-22 JP JP2010098631A patent/JP2010189423A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101432313B1 (ko) * | 2005-11-17 | 2014-08-20 | 노파르티스 아게 | 약제학적 조성물 |
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| AU2002344371A1 (en) | Orally administering parathyroid hormone and calcitonin | |
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