ATE356631T1 - Orale verabreichung von parathyroidhormon und calcitonin - Google Patents

Orale verabreichung von parathyroidhormon und calcitonin

Info

Publication number
ATE356631T1
ATE356631T1 AT02750997T AT02750997T ATE356631T1 AT E356631 T1 ATE356631 T1 AT E356631T1 AT 02750997 T AT02750997 T AT 02750997T AT 02750997 T AT02750997 T AT 02750997T AT E356631 T1 ATE356631 T1 AT E356631T1
Authority
AT
Austria
Prior art keywords
calcitonin
oral administration
parathyroid hormone
pth
effective amount
Prior art date
Application number
AT02750997T
Other languages
English (en)
Inventor
Joseph M Ault
Moise Azria
Simon David Bateman
James F Mcleod
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23136525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE356631(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE356631T1 publication Critical patent/ATE356631T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02750997T 2001-06-01 2002-05-31 Orale verabreichung von parathyroidhormon und calcitonin ATE356631T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29516901P 2001-06-01 2001-06-01

Publications (1)

Publication Number Publication Date
ATE356631T1 true ATE356631T1 (de) 2007-04-15

Family

ID=23136525

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02750997T ATE356631T1 (de) 2001-06-01 2002-05-31 Orale verabreichung von parathyroidhormon und calcitonin

Country Status (25)

Country Link
US (2) US20040186050A1 (de)
EP (1) EP1397156B1 (de)
JP (2) JP5073153B2 (de)
KR (3) KR20090116836A (de)
CN (2) CN1512892A (de)
AT (1) ATE356631T1 (de)
AU (2) AU2002344371B2 (de)
BR (1) BRPI0209748B1 (de)
CA (1) CA2446929C (de)
CO (1) CO5540323A2 (de)
CZ (1) CZ307145B6 (de)
DE (1) DE60218842T2 (de)
EC (1) ECSP034858A (de)
ES (1) ES2282436T3 (de)
HU (1) HU229613B1 (de)
IL (2) IL158777A0 (de)
MX (1) MXPA03011027A (de)
NO (1) NO330093B1 (de)
NZ (1) NZ529439A (de)
PL (1) PL211976B1 (de)
PT (1) PT1397156E (de)
RU (1) RU2300392C2 (de)
SK (1) SK287697B6 (de)
WO (1) WO2002098453A2 (de)
ZA (1) ZA200308625B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2446929C (en) 2001-06-01 2013-04-09 Novartis Ag Orally administering parathyroid hormone and calcitonin
WO2003015822A1 (en) 2001-08-17 2003-02-27 Novartis Ag 5-cnac as oral delivery agent for parathyroid hormone fragments
US20050054557A1 (en) * 2002-05-09 2005-03-10 Goldberg Michael M. Compositions for delivering parathyroid hormone and calcitonin
AU2006292337B8 (en) 2005-09-19 2013-02-07 Emisphere Technologies, Inc. Crystalline forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid
GB0522566D0 (en) * 2005-11-04 2005-12-14 Novartis Ag Organic compounds
CN101355959B (zh) * 2005-11-10 2013-02-27 密歇根理工大学管理委员会 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法
US20080255048A1 (en) * 2005-11-17 2008-10-16 Moise Azria Pharmaceutical Composition
WO2009059188A1 (en) 2007-11-02 2009-05-07 Emisphere Technologies, Inc. Method of treating vitamin b12 deficiency
CN104857505A (zh) * 2008-08-18 2015-08-26 安特拉贝欧有限公司 用于口服给予蛋白质的方法和组合物
CN102123697B (zh) * 2008-08-18 2015-06-10 安特拉贝欧有限公司 用于口服给予蛋白质的方法和组合物
CA2782640A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
WO2012130193A1 (en) 2011-03-31 2012-10-04 Zentiva, K.S. Non-covalent soluble complexes of teriparatide with polysaccharides and a dosage form of teriparatide for oral administration
CN104800564A (zh) * 2015-04-02 2015-07-29 中国人民解放军济南军区总医院 一种治疗血虚不荣型甲状旁腺功能减退症的中药组合物
KR101796604B1 (ko) * 2016-08-30 2017-11-10 목포대학교 산학협력단 위장관 흡수증진제를 함유하는 부갑상선 호르몬의 경구 투여 제형
JP6944221B2 (ja) 2017-11-20 2021-10-06 ノブメタファーマ カンパニー リミテッド Ｃｈｐ（シクロ−ヒスプロ）を含む骨損失疾患の予防、改善または治療用組成物
KR102115353B1 (ko) * 2019-05-17 2020-05-26 주식회사 노브메타파마 Chp(사이클로-히스프로) 및 부갑상선 호르몬을 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692433A (en) * 1983-10-12 1987-09-08 The Regents Of The University Of California Method and composition for regulating serum calcium levels of mammals
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
US5118667A (en) * 1991-05-03 1992-06-02 Celtrix Pharmaceuticals, Inc. Bone growth factors and inhibitors of bone resorption for promoting bone formation
WO1994018955A1 (en) * 1993-02-22 1994-09-01 Alza Corporation Compositions for oral delivery of active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5955574A (en) * 1995-07-13 1999-09-21 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. Analogs of parathyroid hormone
US5723577A (en) 1995-07-13 1998-03-03 Biomeasure Inc. Analogs of parathyroid hormone
JP4975201B2 (ja) 1997-02-07 2012-07-11 エミスフェアー・テクノロジーズ・インク 化合物及び活性剤を送達するための組成物
TW577759B (en) * 1997-04-18 2004-03-01 Ipsen Pharma Biotech Sustained release compositions in the form of microcapsules or implants and the process for their preparation
SE9702401D0 (sv) 1997-06-19 1997-06-19 Astra Ab Pharmaceutical use
DE19915272A1 (de) * 1999-04-03 2000-10-05 Vetter & Co Apotheker Spritze für medizinische Zwecke
NZ534409A (en) * 1999-04-05 2006-03-31 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
WO2001032201A2 (en) 1999-10-29 2001-05-10 Eli Lilly And Company A pharmaceutical composition having high cell membrane permeability
US7049283B2 (en) * 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
CA2446929C (en) 2001-06-01 2013-04-09 Novartis Ag Orally administering parathyroid hormone and calcitonin
WO2003015822A1 (en) * 2001-08-17 2003-02-27 Novartis Ag 5-cnac as oral delivery agent for parathyroid hormone fragments
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone

Also Published As

Publication number Publication date
US20080119411A1 (en) 2008-05-22
US20040186050A1 (en) 2004-09-23
RU2003136733A (ru) 2005-05-20
PL211976B1 (pl) 2012-07-31
HUP0400120A3 (en) 2012-09-28
ES2282436T3 (es) 2007-10-16
JP2005500277A (ja) 2005-01-06
DE60218842T2 (de) 2007-12-20
KR20090116836A (ko) 2009-11-11
JP2010189423A (ja) 2010-09-02
CN1512892A (zh) 2004-07-14
NO20035133L (no) 2003-11-18
CA2446929C (en) 2013-04-09
KR20120065429A (ko) 2012-06-20
US8153587B2 (en) 2012-04-10
NO330093B1 (no) 2011-02-14
BR0209748A (pt) 2004-07-27
EP1397156B1 (de) 2007-03-14
AU2006225157B2 (en) 2009-04-23
WO2002098453A2 (en) 2002-12-12
HU229613B1 (en) 2014-03-28
KR101320817B1 (ko) 2013-10-21
CZ307145B6 (cs) 2018-02-07
NO20035133D0 (no) 2003-11-18
KR20040007617A (ko) 2004-01-24
JP5073153B2 (ja) 2012-11-14
BRPI0209748B1 (pt) 2015-11-24
CZ20033232A3 (cs) 2004-06-16
CN101837120A (zh) 2010-09-22
RU2300392C2 (ru) 2007-06-10
EP1397156A2 (de) 2004-03-17
PL364089A1 (en) 2004-12-13
CO5540323A2 (es) 2005-07-29
IL158777A0 (en) 2004-05-12
ZA200308625B (en) 2004-07-13
MXPA03011027A (es) 2004-03-19
AU2002344371B2 (en) 2006-06-29
SK287697B6 (sk) 2011-06-06
HUP0400120A2 (hu) 2005-04-28
WO2002098453A3 (en) 2003-07-31
DE60218842D1 (de) 2007-04-26
AU2006225157A1 (en) 2006-10-19
PT1397156E (pt) 2007-05-31
NZ529439A (en) 2005-11-25
ECSP034858A (es) 2004-01-28
IL158777A (en) 2012-06-28
SK14752003A3 (sk) 2004-06-08
CA2446929A1 (en) 2002-12-12

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