KR20040003021A - 치료에 유용한 니코틴성 아세틸콜린 수용체에 대한 신규리간드 - Google Patents

치료에 유용한 니코틴성 아세틸콜린 수용체에 대한 신규리간드 Download PDF

Info

Publication number
KR20040003021A
KR20040003021A KR10-2003-7015462A KR20037015462A KR20040003021A KR 20040003021 A KR20040003021 A KR 20040003021A KR 20037015462 A KR20037015462 A KR 20037015462A KR 20040003021 A KR20040003021 A KR 20040003021A
Authority
KR
South Korea
Prior art keywords
disorder
disease
compound
treatment
prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR10-2003-7015462A
Other languages
English (en)
Korean (ko)
Inventor
에이피온 필립스
Original Assignee
아스트라제네카 아베
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20040003021A publication Critical patent/KR20040003021A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR10-2003-7015462A 2001-06-01 2002-05-29 치료에 유용한 니코틴성 아세틸콜린 수용체에 대한 신규리간드 Ceased KR20040003021A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29520601P 2001-06-01 2001-06-01
US60/295,206 2001-06-01
PCT/SE2002/001031 WO2002096912A1 (en) 2001-06-01 2002-05-29 Novel ligand for nicotinic acetylcholine receptors useful in therapy

Publications (1)

Publication Number Publication Date
KR20040003021A true KR20040003021A (ko) 2004-01-07

Family

ID=23136711

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7015462A Ceased KR20040003021A (ko) 2001-06-01 2002-05-29 치료에 유용한 니코틴성 아세틸콜린 수용체에 대한 신규리간드

Country Status (18)

Country Link
EP (1) EP1397366B1 (https=)
JP (1) JP2004532877A (https=)
KR (1) KR20040003021A (https=)
CN (1) CN1294136C (https=)
AT (1) ATE353332T1 (https=)
BR (1) BR0210075A (https=)
CA (1) CA2455341A1 (https=)
DE (1) DE60218032T2 (https=)
DK (1) DK1397366T3 (https=)
ES (1) ES2280538T3 (https=)
IL (1) IL158735A0 (https=)
MX (1) MXPA03010996A (https=)
NO (1) NO20035333D0 (https=)
NZ (1) NZ529426A (https=)
PT (1) PT1397366E (https=)
SI (1) SI1397366T1 (https=)
WO (1) WO2002096912A1 (https=)
ZA (1) ZA200308779B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
EP1499618B1 (en) * 2002-04-18 2010-10-13 AstraZeneca AB Furyl compounds
BR0309342A (pt) 2002-04-18 2005-02-15 Astrazeneca Ab Composto, composição farmacêutica, uso de um composto, e, método de tratamento ou profilaxia de doenças ou condições humanas
US7417050B2 (en) * 2002-04-18 2008-08-26 Astrazeneca Ab Heterocyclic compounds
EP1678183A1 (en) * 2003-10-21 2006-07-12 AstraZeneca AB Spirofuropyridine aryl derivatives
TW200813067A (en) * 2006-05-17 2008-03-16 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
MX2010014203A (es) 2008-06-20 2011-02-22 Astrazeneca Ab Derivados de dibenzotiazepina y sus usos - 424.
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
AR081402A1 (es) 2010-05-17 2012-08-29 Envivo Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il) benzo(b)tiofeno-2-carboxamida monohidrato
GB201111705D0 (en) 2011-07-07 2011-08-24 Takeda Pharmaceutical Compounds and their use
GB201111704D0 (en) 2011-07-07 2011-08-24 Takeda Pharmaceutical Novel compounds
JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
CA2872005A1 (en) 2012-05-08 2013-11-14 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
GB201209587D0 (en) 2012-05-30 2012-07-11 Takeda Pharmaceutical Therapeutic compounds
WO2014122474A1 (en) 2013-02-07 2014-08-14 Takeda Pharmaceutical Company Limited Piperidin-1 -yl and azepin-1 -yl carboxylates as muscarinic m4 receptor agonists
HK1219722A1 (zh) 2013-06-21 2017-04-13 Takeda Pharmaceutical Company Limited 1-磺酰基派啶衍生物作为前动力蛋白受体的调节剂
GB201314286D0 (en) 2013-08-08 2013-09-25 Takeda Pharmaceutical Therapeutic Compounds
GB201318222D0 (en) 2013-10-15 2013-11-27 Takeda Pharmaceutical Novel compounds
GB201320905D0 (en) 2013-11-27 2014-01-08 Takeda Pharmaceutical Therapeutic compounds
TW201613864A (en) 2014-02-20 2016-04-16 Takeda Pharmaceutical Novel compounds
GB201616839D0 (en) 2016-10-04 2016-11-16 Takeda Pharmaceutical Company Limited Therapeutic compounds
GB201619514D0 (en) 2016-11-18 2017-01-04 Takeda Pharmaceuticals Co Novel compounds
JP2021138648A (ja) 2020-03-04 2021-09-16 武田薬品工業株式会社 経口固形製剤
GB202414193D0 (en) 2024-09-27 2024-11-13 Addex Pharmaceuticals Sa Novel compounds
GB202414197D0 (en) 2024-09-27 2024-11-13 Addex Pharmaceuticals Sa Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002500652A (ja) * 1997-05-30 2002-01-08 ニューロサーアチ・アクティーゼルスカブ スピロ−キヌクリジン誘導体、その製造方法及びその使用方法
AR013184A1 (es) * 1997-07-18 2000-12-13 Astrazeneca Ab Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
SE9900100D0 (sv) * 1999-01-15 1999-01-15 Astra Ab New compounds

Also Published As

Publication number Publication date
ES2280538T3 (es) 2007-09-16
EP1397366B1 (en) 2007-02-07
NO20035333D0 (no) 2003-11-28
ZA200308779B (en) 2005-02-11
MXPA03010996A (es) 2004-02-27
CN1512995A (zh) 2004-07-14
BR0210075A (pt) 2004-08-17
EP1397366A1 (en) 2004-03-17
DE60218032D1 (de) 2007-03-22
IL158735A0 (en) 2004-05-12
NZ529426A (en) 2005-07-29
PT1397366E (pt) 2007-04-30
DE60218032T2 (de) 2007-08-16
CN1294136C (zh) 2007-01-10
HK1063787A1 (en) 2005-01-14
ATE353332T1 (de) 2007-02-15
DK1397366T3 (da) 2007-05-07
JP2004532877A (ja) 2004-10-28
SI1397366T1 (sl) 2007-06-30
WO2002096912A1 (en) 2002-12-05
CA2455341A1 (en) 2002-12-05

Similar Documents

Publication Publication Date Title
KR20040003021A (ko) 치료에 유용한 니코틴성 아세틸콜린 수용체에 대한 신규리간드
EP1213291B1 (en) Spiro [1-azabicyclo[2.2.2]octane-3,2'(3'H)-furo[2,3-b]pyridine for use in the treatment of psychotic and intellectual impairment disorders
US7417049B2 (en) Furyl compounds
RU2233282C2 (ru) Аралкиламины фуропиридинов, способ их получения, фармацевтическая композиция на их основе и промежуточные вещества
US7417050B2 (en) Heterocyclic compounds
US6569865B2 (en) Spiro 1-azabicyclo[2.2.2]octane-3,2′(3′h)-furo[2,3-b]pyridine
US20070142419A1 (en) Thienyl Compounds
AU2004285751B2 (en) Spirofuropyridine aryl derivatives
US20070191422A1 (en) Nicotinic acetylcholine receptor ligands
US20070244097A1 (en) Nicotinic AcetylcholineReceptor Ligands
AU2002303064A1 (en) Novel ligand for nicotinic acetylcholine receptors useful in therapy
US20070105896A1 (en) 4-Substituted imidazoles
HK1063787B (en) Novel ligand for nicotinic acetylcholine receptors useful in therapy
KR20060125812A (ko) 니코틴성 아세틸콜린 수용체 리간드
US20080188518A1 (en) 5-Substituted Imidazoles
KR20070020445A (ko) 알파 7 니코틴성 아세틸콜린 수용체를 위한 신규한2-(1-아자-비시클로[2.2.2]옥트-3-일)-2,3-디히드로이소인돌-1-온/5,6-디히드로-푸로[2,3-ｃ]피롤-4-온 유도체리간드

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20031127

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20070125

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20071130

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20080219

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20071130

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I