KR20030060910A - 비이식 척수 융합 장치 - Google Patents

비이식 척수 융합 장치 Download PDF

Info

Publication number
KR20030060910A
KR20030060910A KR10-2003-7005156A KR20037005156A KR20030060910A KR 20030060910 A KR20030060910 A KR 20030060910A KR 20037005156 A KR20037005156 A KR 20037005156A KR 20030060910 A KR20030060910 A KR 20030060910A
Authority
KR
South Korea
Prior art keywords
spinal cord
implant
implantable spinal
implantable
bioactive coating
Prior art date
Application number
KR10-2003-7005156A
Other languages
English (en)
Inventor
마이클 디. 메이슨
Original Assignee
마이클 디. 메이슨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 마이클 디. 메이슨 filed Critical 마이클 디. 메이슨
Publication of KR20030060910A publication Critical patent/KR20030060910A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/447—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/3011—Cross-sections or two-dimensional shapes
    • A61F2002/30112—Rounded shapes, e.g. with rounded corners
    • A61F2002/30131—Rounded shapes, e.g. with rounded corners horseshoe- or crescent- or C-shaped or U-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/3011—Cross-sections or two-dimensional shapes
    • A61F2002/30138—Convex polygonal shapes
    • A61F2002/30153—Convex polygonal shapes rectangular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/30224—Three-dimensional shapes cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30769—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth madreporic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30795—Blind bores, e.g. of circular cross-section
    • A61F2002/30807—Plurality of blind bores
    • A61F2002/30808—Plurality of blind bores parallel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30879—Ribs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30879—Ribs
    • A61F2002/30883—Ribs dovetail-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30884—Fins or wings, e.g. longitudinal wings for preventing rotation within the bone cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017—Angular shapes
    • A61F2230/0019—Angular shapes rectangular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0069—Three-dimensional shapes cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00359—Bone or bony tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Prostheses (AREA)
  • Fertilizing (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Materials For Medical Uses (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Massaging Devices (AREA)
  • Separation By Low-Temperature Treatments (AREA)

Abstract

2개의 인접한 척추를 기계적으로 부착하기 위한 비이식 척수 임플란트는 제1 및 제2 대향 표면들을 구비한 본체를 포함한다. 제1 및 제2 표면들은 인접한 척추에 본체를 고정하기 위한 적어도 하나의 돌기 부재를 포함하고, 그 본체의 외부면들과 제1 및 제2 돌기 부재들은 생체 활성 코팅을 포함한다. 생체 활성 코팅은 예컨대 하이드록시애퍼타이트와 같은 코팅들로부터 선택될 수 있다. 외부 생체 활성 코팅은 이식가능한 척수 융합 장치 및 인접한 척추 사이에 척추 뼈의 표면성장/내부성장을 용이하게 한다. 유리하게도, 이것은 뼈 이식제 및/또는 뼈 성장제의 사용을 피하게 한다.

Description

비이식 척수 융합 장치 {GRAFTLESS SPINAL FUSION DEVICE}
미국 특허 제6,241,769호("척수 융합용 임플란트") 및 미국 특허 제6,096,080호("임플란트 장치를 사용하는 척수 융합용 장치")는 척수 대체 장치를 개시한다. 2개의 특허들은 종래 기술의 장치들과 관련된 문제점들을 상세하게 설명한다.
참고문헌으로 본문에서 참조되는 미국 특허 제6,241,769호 및 6,096,080호에 개시된 장치들은 인접한 뼈 표면들에 장기간의 고정을 향상시키도록 중앙 이식 공간을 이용한다. 장치는 산호 또는 인산 칼슘과 같은 뼈 대체 재료의 인뼈 동종이식 재료로부터 제조될 수 있다. 이러한 특허들에 개시된 장치가 갖는 문제점들은 이러한 장치들은 뼈 이식을 요구하고 이러한 타입의 장치들의 파손율이 현격하게 높다는 점이다. 또한, 수용불가한 높은 이환율(예를 들어, 30%)을 가진다는 것이다.
따라서, 인접한 척추(vertebral) 뼈 표면들에 임플란트 장치의 고정을 용이하게 하기 위한 시도에서 뼈 이식을 이용하지 않는 척수 임플란트 장치가 필요하게 되어 척수 이동 분절을 안정화시킨다.
본 출원은 참고문헌으로 본문에 참조되는 2000년 10월 11일 출원된 가출원 지정 번호 60/239,368호("척수 융합 장치")로부터 우선권을 주장한다.
본 발명은 척수 임플란트(spinal implant)에 관한 것으로서, 특히 뼈 표면에 인접하게 임플란트의 고정을 향상시키도록 하이드록시애퍼타이트(hydroxyapatite)와 같은 생체 활성 코팅을 이용하는 비이식 척수 임플란트에 관한 것이다.
도1은 비이식 척수 임플란트의 제1 실시예의 사시도이다.
도2는 척수 내에 작동가능하게 임플란트된 비이식 척수 임플란트의 정면도이다.
도3은 도2에 도시된 비이식 척수 임플란트의 측면도이다.
도4는 비이식 척추 임플란트의 제2 실시예의 사시도이다.
도5 및 도6은 도4에 도시된 비이식 척수 임플란트(20)의 추가적 사시도이다.
도7은 비이식 척수 임플란트의 다른 실시예의 도면이다.
간략하게, 본 발명에 따르면 임플란트가능한 척수 융합 장치는 외향 생체 활성 코팅을 포함한다.
일실시예에서, 2개의 인접한 척추를 기계적으로 부착하기 위한 비이식 척수 임플란트는 제1 및 제2 대향 표면들을 구비하는 본체를 포함한다. 제1 및 제2 표면들은 본체를 인접 척추에 고정시키기 위한 적어도 하나의 돌기 부재를 포함하고, 본체의 외향 표면들, 제1 및 제2 돌기 부재들은 생체 활성 코팅을 포함한다.
생체 활성 코팅은 예를 들어, 하이드록시애퍼타이트, 생체 유리(bioglass), 생체 복합제(biocomposites), 하이드록시애퍼타이트 트리칼슘 인산염(hydroxypatite tricalcium phosphate), 뼈 형태 형성 단백질(bone morphogenic protein) 또는 다른 뼈 생성 단백질과 같은 코팅으로부터 선택될 수 있다.
외부 생체 활성 코팅은 임플란트할 수 있는 척수 융합 장치와 인접한 척추 사이에 척추뼈의 표면 성장/ 내부 성장을 용이하게 한다. 장점으로서, 이것은 장치가 뼈 이식 및/또는 뼈 성장제의 사용을 방지하게 한다.
본 발명의 이러한 및 다른 목적, 특징 및 장점은 다음의 도면에 도시된 바와같이 양호한 실시예의 다음의 상세한 설명을 참조하여 명백해진다.
도1은 비이식 척수 전방 융합 장치(10)를 도시한다. 장치(10)는 본 실시예에서 실질적으로 직사각형의 형상을 한 본체(12)를 포함한다. 그러나, 보통의 기술자는 본체(12)가 직사각형 이외의 형상으로 형성될 수 있다는 것을 인지한다. 본체(12)는 또한 각각 제1 및 제2 대향 표면(14, 16)을 포함한다. 이러한 실시예에서, 제1 및 제2 표면(14, 16)은 실질적으로 평행하고 돌기 부재(18 내지 21)를 포함한다. 본체 및 돌기 부재는 바람직하게는 1 피스(즉, 단일) 구조이다. 장치(10)는 또한 완만한 커브/테이퍼질 수 있다.
도2는 척추(24) 내에 작동 가능하게 임플란트된 비이식 척수 전방 융합 장치(10)의 간략화된 도면이다. 척수는 척추(vertebrae, 26, 28) 및 천연 디스크(natural disks, 30, 32) 또한, 척수(24)는 부분적으로 제거되어 본 발명의비이식 척수 전방 융합 장치로 교체되는 병든/손상된 디스크(34)를 포함한다. 비이식 척수 전방 융합 장치(10)의 외과적인 삽입을 위한 준비 단계에서, 관련 돌기 부재(예컨대, 18 내지 21)를 견고하게 수용하도록 된 크기를 갖는 키웨이(36 내지 39, keyway)는 손상된/병든 디스크에 인접하여 위치된 각각의 척추(26, 28) 내에 형성된다.
도3은 도2에 도시된 비이식 척수 임플란트(10)의 측면을 도시한다. 특히, 연장 및 회전력은 돌기 부재에 의해 상쇄된다.
본 발명의 일 측면에 따르면, 장치(10)는 예컨대 하이드록시애퍼타이트(hydroxyapatite), 생체 유리(bioglass), 생체 복합재(biocomposites), 하이드록시퍼타이트 트리칼슘 인산염, 뼈 형태 형성 단백질 또는 다른 뼈 생성 단백질과 같은 생체 활성 코팅으로 코팅된다. 중요하게는, 생체 활성 코팅은 척추 뼈의 표면 성장/내부 성장을 촉진한다.
도4는 비이식 척수 임플란트(70)의 제2 실시예의 사시도를 도시한다. 이 실시예는 또한 실질적으로 직사각형형인 본체(72)와, 제1 및 제2 대향 표면(80, 82)의 각각으로부터 연장하는 적어도 하나의 돌기부(예컨대, 74 내지 77)를 포함한다. 특히, 돌기부(74 내지 77)는 실질적으로 원통형으로 형성된다. 물론, 인접 척추 내에 형성된 키웨이(keyway, 도시 생략)는 돌기부(74 내지 77)를 수용하도록 형성된다. 부가하여, 이 비이식 척수 임플란트(70)의 외부면은 직물의 짜임을 갖거나 거칠고, 임플란트의 표면 면적을 증가시키는 복수의 함몰부(79)를 포함한다. 즉, 바람직하게는 비이식 척수 임플란트(70)의 외부면은 임플란트와 인접 뼈의 융합을촉진하도록 복수의 얕은 함몰부(79)를 포함한다. 직물의 짜임을 갖는 표면은 비드(beads), 호형 퇴적물(arc deposits) 및/또는 합성 포움(systhetic foams)을 포함할 수 있다. 임플란트(70)의 외부면은, 예컨대 하이드록시애퍼타이트와 같은 생체 활성 코팅으로 코팅되어 있다. 이 코팅은 척추 뼈의 표면 성장/내부 성장을 촉진한다. 바람직한 실시예의 도1 내지 도4에 도시된 장치의 외부면은 바람직하게는 유사하게 거칠게 되어 있고 복수의 함몰부를 포함한다.
다른 실시예에서, 임플란트(70)는 본 명세서에 참고로 포함된 상술한 미국 특허들에 개시된 바와 같이 뼈 성장제가 위치될 수 있는 개구(84)를 포함할 수 있다. 최종적인 장치는 개구 내에 위치되는 뼈 이식 재료의 포함으로 인하여 진정한 비이식 장치로서 더 이상 고려될 수 없을 수 있다. 중요하게는, 이 장치는 전술한 비이식 장치의 장점과 종래 기술의 이식 기술의 특징을 포함한다. 개구(84)는 본체(72)를 통해 연장될 수 있고(즉, 이는 관통 구멍), 또는 이는 본체(72)를 통해 부분적으로만 연장될 수 있다. 개구를 형성하는 표면은 감촉이 부드러운/거칠 수 있고, 얕은 만입부/구멍을 포함한다.
도5 및 도6은 비이식 척수 임플란트(7)의 부가적인 사시도이다.
도7은 비이식 척수 임플란트(100)의 다른 실시예의 사시도이다. 이러한 척수 임플란트는 상기 장치의 적어도 한 측에 테이퍼 엣지(102)를 포함하는 실시예를 제외하고는 도4 내지 도6에 도시된 임플란트와 동일하다. 테이퍼 엣지(102)는 임플란트를 척추에 절단된 키웨이(도시 생략)로 삽입하는 것을 용이하게 한다. 이러한 실시예에서, 임플란트(100)는 예로써 하이드록시애퍼타이트(hydroxyapatite)와같은 생체 활성 코팅으로 코팅된다.
상기 임플란트는 그 자체가 티타늄, 폴리페놀슐폰(polyphenolsulfone), 폴리아리레테르케톤(polyaryletherketone; PEEK), 폴리슐폰, 아세탈[acetal; 델린(delrin)], UHMW 폴리에틸렌과 같은 다양한 현재 입수가능한 생물학적으로 양립할 수 있는 재료와, 인장 강도 및 전단 강도를 부가하기 위한 고강도 탄소 섬유 또는 REM 유리 필라멘트와 관련된 이러한 재료의 혼합물을 포함할 수 있다. 상기 임플란트는 인간 뼈 타가 이식 재료, 자가 이식체 또는 산호 또는 인산 칼슘과 같은 뼈 대체 재료로 제조될 수 있다. 임플란트의 본체는 선택적으로 적절한 테이퍼를 가질 수 있다.
비록 상기 설명한 실시예에는 실질적으로 도브테일형 또는 원통형/편자형인 돌기 부재를 채용하였지만, 본질적으로 소정의 형상의 돌기 부재가 본 발명의 생체 활성 코팅식 임플란트에 사용될 수 있다는 것을 알 수 있다.
본 발명이 몇몇 양호한 실시예에 대해 도시하고 설명하였지만, 본 발명의 기술 사상 및 범위 내에서 그 형상 및 세밀한 점에 다양한 변경, 생략 및 추가가 가능하다는 것을 알아야 한다.

Claims (7)

  1. 2개의 인접한 척추를 기계적으로 부착하기 위한 비이식 척수 임플란트이며,
    제1 및 제2 대향 표면들을 구비한 본체와,
    제1 및 제2 표면들의 각각은 상기 본체를 인접한 척추에 고정하기 위한 적어도 하나의 돌기 부재를 포함하고, 상기 본체의 외부면들과 제1 및 제2 돌기 부재들은 생체 활성 코팅을 포함하는 것을 특징으로 하는 비이식 척수 임플란트.
  2. 제1항에 있어서, 상기 생체 활성 코팅은 하이드록시애퍼타이트를 포함하는 것을 특징으로 하는 비이식 척수 임플란트.
  3. 제2항에 있어서, 상기 돌기 부재들은 도버테일형의 설부 돌기로 형성된 것을 특징으로 하는 비이식 척수 임플란트.
  4. 제2항에 있어서, 상기 본체는 실질적으로 직사각형인 것을 특징으로 하는 비이식 척수 임플란트.
  5. 제2항에 있어서, 상기 돌기 부재들은 편자 형상의 설부 돌기로 형성된 것을 특징으로 하는 비이식 척수 임플란트.
  6. 비이식 척수 임플란트를 형성하는 방법이며,
    척수 임플란트를 제공하는 단계와,
    상기 척수 임플란트의 외부면을 생체 활성 코팅으로 코팅하는 단계를 포함하는 것을 특징으로 하는 비이식 척수 임플란트 형성 방법.
  7. 제6항에 있어서, 상기 생체 활성 코팅은 하이드록시애퍼타이트를 포함하는 것을 특징으로 하는 비이식 척수 임플란트 형성 방법.
KR10-2003-7005156A 2000-10-11 2001-10-11 비이식 척수 융합 장치 KR20030060910A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23936800P 2000-10-11 2000-10-11
US60/239,368 2000-10-11
PCT/US2001/031821 WO2002030337A2 (en) 2000-10-11 2001-10-11 Graftless spinal fusion device

Publications (1)

Publication Number Publication Date
KR20030060910A true KR20030060910A (ko) 2003-07-16

Family

ID=22901865

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2003-7005156A KR20030060910A (ko) 2000-10-11 2001-10-11 비이식 척수 융합 장치

Country Status (10)

Country Link
US (2) US6743256B2 (ko)
EP (2) EP1576938B1 (ko)
JP (1) JP4472925B2 (ko)
KR (1) KR20030060910A (ko)
AT (2) ATE296073T1 (ko)
AU (2) AU2002213124B2 (ko)
CA (1) CA2425500C (ko)
DE (2) DE60111069D1 (ko)
NZ (1) NZ525798A (ko)
WO (1) WO2002030337A2 (ko)

Families Citing this family (194)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800093B2 (en) * 1998-05-06 2004-10-05 Cortek, Inc. Device for spinal fusion
EP1681021A3 (en) * 1998-06-09 2009-04-15 Warsaw Orthopedic, Inc. Abrading element for preparing a space between adjacent vertebral bodies
US6083228A (en) * 1998-06-09 2000-07-04 Michelson; Gary K. Device and method for preparing a space between adjacent vertebrae to receive an insert
ES2303381T3 (es) * 1999-07-02 2008-08-01 Spine Solutions Inc. Implante intervertebral.
FR2897259B1 (fr) 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si Cage intersomatique transforaminale a greffon de fusion intervetebrale et instrument d'implantation de la cage
DE29924979U1 (de) 1999-09-14 2007-07-12 Spine Solutions, Inc. Einsetzinstrument für ein Zwischenwirbelimplantat
FR2808995B1 (fr) 2000-05-18 2003-02-21 Aesculap Sa Cage intersomatique a greffons unifies
US6692501B2 (en) * 2000-12-14 2004-02-17 Gary K. Michelson Spinal interspace shaper
US6743257B2 (en) * 2000-12-19 2004-06-01 Cortek, Inc. Dynamic implanted intervertebral spacer
ATE419810T1 (de) * 2001-05-01 2009-01-15 Amedica Corp Röntgendurchlässiges knochentransplantat
WO2002102275A2 (en) * 2001-06-14 2002-12-27 Amedica Corporation Metal-ceramic composite articulation
FR2827156B1 (fr) * 2001-07-13 2003-11-14 Ldr Medical Dispositif de cage vertebrale avec fixation modulaire
DE10152567A1 (de) * 2001-10-24 2003-05-08 Tutogen Medical Gmbh Implantat
US6740118B2 (en) * 2002-01-09 2004-05-25 Sdgi Holdings, Inc. Intervertebral prosthetic joint
AR038680A1 (es) 2002-02-19 2005-01-26 Synthes Ag Implante intervertebral
US7204852B2 (en) 2002-12-13 2007-04-17 Spine Solutions, Inc. Intervertebral implant, insertion tool and method of inserting same
JP2006510452A (ja) * 2002-12-17 2006-03-30 アメディカ コーポレイション 総椎間板インプラント
EP1587462B1 (en) * 2003-01-31 2012-06-06 Malan De Villiers Intervertebral prosthesis placement instrument
ES2358586T3 (es) 2003-02-06 2011-05-12 Synthes Gmbh Implante intervertebral.
US20040158329A1 (en) * 2003-02-10 2004-08-12 Waldemar Link (Gmbh & Co.) Hip joint prosthesis with shaft inserted into femur
ATE505156T1 (de) * 2003-02-12 2011-04-15 Warsaw Orthopedic Inc Vorrichtung zur fusion zweier knochensegmente
US7918876B2 (en) * 2003-03-24 2011-04-05 Theken Spine, Llc Spinal implant adjustment device
US7491204B2 (en) 2003-04-28 2009-02-17 Spine Solutions, Inc. Instruments and method for preparing an intervertebral space for receiving an artificial disc implant
US7803162B2 (en) * 2003-07-21 2010-09-28 Spine Solutions, Inc. Instruments and method for inserting an intervertebral implant
US7041137B2 (en) * 2003-10-07 2006-05-09 Lanx, Llc Spinal implant
US20050149192A1 (en) * 2003-11-20 2005-07-07 St. Francis Medical Technologies, Inc. Intervertebral body fusion cage with keels and implantation method
US7837732B2 (en) 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US7550010B2 (en) * 2004-01-09 2009-06-23 Warsaw Orthopedic, Inc. Spinal arthroplasty device and method
US7771479B2 (en) 2004-01-09 2010-08-10 Warsaw Orthopedic, Inc. Dual articulating spinal device and method
CN101961270B (zh) 2004-02-04 2016-08-10 Ldr医学公司 椎间盘假体
US7485145B2 (en) * 2004-02-23 2009-02-03 Alphatec Spine, Incorporated Artificial intervertebral disc assembly
US7749268B2 (en) 2004-05-26 2010-07-06 Warsaw Orthopedic, Inc. Methods for treating the spine
DE102004026617B4 (de) * 2004-06-01 2006-06-14 Siemens Ag Vorrichtung zum Verklemmen von Gewebe
US20060009845A1 (en) * 2004-07-08 2006-01-12 Chin Kingsley R Method and device for kinematic retaining cervical plating
EP1623685A1 (de) * 2004-08-06 2006-02-08 WALDEMAR LINK GmbH & Co. KG Hüftgelenkprothese mit einem in den Oberschenkelknochen einzusetzenden Schaft
US8425570B2 (en) 2004-08-09 2013-04-23 Si-Bone Inc. Apparatus, systems, and methods for achieving anterior lumbar interbody fusion
US20180228621A1 (en) * 2004-08-09 2018-08-16 Mark A. Reiley Apparatus, systems, and methods for the fixation or fusion of bone
US20070156241A1 (en) 2004-08-09 2007-07-05 Reiley Mark A Systems and methods for the fixation or fusion of bone
US8388667B2 (en) * 2004-08-09 2013-03-05 Si-Bone, Inc. Systems and methods for the fixation or fusion of bone using compressive implants
US8470004B2 (en) 2004-08-09 2013-06-25 Si-Bone Inc. Apparatus, systems, and methods for stabilizing a spondylolisthesis
US9662158B2 (en) 2004-08-09 2017-05-30 Si-Bone Inc. Systems and methods for the fixation or fusion of bone at or near a sacroiliac joint
US8414648B2 (en) * 2004-08-09 2013-04-09 Si-Bone Inc. Apparatus, systems, and methods for achieving trans-iliac lumbar fusion
US8444693B2 (en) * 2004-08-09 2013-05-21 Si-Bone Inc. Apparatus, systems, and methods for achieving lumbar facet fusion
US9949843B2 (en) 2004-08-09 2018-04-24 Si-Bone Inc. Apparatus, systems, and methods for the fixation or fusion of bone
US20060036251A1 (en) 2004-08-09 2006-02-16 Reiley Mark A Systems and methods for the fixation or fusion of bone
JP4559482B2 (ja) * 2004-08-13 2010-10-06 シンテス ゲーエムベーハー 棘突起間インプラント
US8172855B2 (en) 2004-11-24 2012-05-08 Abdou M S Devices and methods for inter-vertebral orthopedic device placement
US7967823B2 (en) * 2005-01-31 2011-06-28 Arthrex, Inc. Method and apparatus for performing an open wedge, high tibial osteotomy
US8911498B2 (en) * 2005-02-10 2014-12-16 DePuy Synthes Products, LLC Intervertebral prosthetic disc
US7690381B2 (en) * 2005-02-10 2010-04-06 Depuy Spine, Inc. Intervertebral prosthetic disc and method for installing using a guidewire
US8585766B2 (en) 2005-05-06 2013-11-19 Titan Spine, Llc Endplate-preserving spinal implant with an integration plate having durable connectors
US8585765B2 (en) 2005-05-06 2013-11-19 Titan Spine, Llc Endplate-preserving spinal implant having a raised expulsion-resistant edge
US8551176B2 (en) 2005-05-06 2013-10-08 Titan Spine, Llc Spinal implant having a passage for enhancing contact between bone graft material and cortical endplate bone
US8617248B2 (en) 2005-05-06 2013-12-31 Titan Spine, Llc Spinal implant having variable ratios of the integration surface area to the axial passage area
US8814939B2 (en) 2005-05-06 2014-08-26 Titan Spine, Llc Implants having three distinct surfaces
US8591590B2 (en) * 2005-05-06 2013-11-26 Titan Spine, Llc Spinal implant having a transverse aperture
US8562685B2 (en) 2005-05-06 2013-10-22 Titan Spine, Llc Spinal implant and integration plate for optimizing vertebral endplate contact load-bearing edges
US8585767B2 (en) 2005-05-06 2013-11-19 Titan Spine, Llc Endplate-preserving spinal implant with an integration plate having durable connectors
US11096796B2 (en) 2005-05-06 2021-08-24 Titan Spine, Llc Interbody spinal implant having a roughened surface topography on one or more internal surfaces
US9125756B2 (en) 2005-05-06 2015-09-08 Titan Spine, Llc Processes for producing regular repeating patterns on surfaces of interbody devices
US8758443B2 (en) 2005-05-06 2014-06-24 Titan Spine, Llc Implants with integration surfaces having regular repeating surface patterns
US9168147B2 (en) 2005-05-06 2015-10-27 Titan Spine, Llc Self-deploying locking screw retention device
US8758442B2 (en) 2005-05-06 2014-06-24 Titan Spine, Llc Composite implants having integration surfaces composed of a regular repeating pattern
US8435302B2 (en) 2005-05-06 2013-05-07 Titan Spine, Llc Instruments and interbody spinal implants enhancing disc space distraction
US8545568B2 (en) 2005-05-06 2013-10-01 Titan Spine, Llc Method of using instruments and interbody spinal implants to enhance distraction
US8262737B2 (en) 2005-05-06 2012-09-11 Titan Spine, Llc Composite interbody spinal implant having openings of predetermined size and shape
US20120312779A1 (en) 2005-05-06 2012-12-13 Titian Spine, LLC Methods for manufacturing implants having integration surfaces
US8992622B2 (en) 2005-05-06 2015-03-31 Titan Spine, Llc Interbody spinal implant having a roughened surface topography
US8562684B2 (en) 2005-05-06 2013-10-22 Titan Spine, Llc Endplate-preserving spinal implant with an integration plate having a roughened surface topography
US20060282166A1 (en) * 2005-06-09 2006-12-14 Sdgi Holdings, Inc. Compliant porous coating
FR2891135B1 (fr) 2005-09-23 2008-09-12 Ldr Medical Sarl Prothese de disque intervertebral
DE102005061932A1 (de) 2005-12-23 2007-07-05 Biedermann Motech Gmbh Mehrwandiger Platzhalter
US8062372B2 (en) * 2005-12-29 2011-11-22 Industrial Technology Research Institute Spinal fusion device
US7811326B2 (en) * 2006-01-30 2010-10-12 Warsaw Orthopedic Inc. Posterior joint replacement device
US7635389B2 (en) * 2006-01-30 2009-12-22 Warsaw Orthopedic, Inc. Posterior joint replacement device
US20070179618A1 (en) * 2006-01-31 2007-08-02 Sdgi Holdings, Inc. Intervertebral prosthetic disc
US20070179615A1 (en) * 2006-01-31 2007-08-02 Sdgi Holdings, Inc. Intervertebral prosthetic disc
WO2007098288A2 (en) * 2006-02-27 2007-08-30 Synthes (U.S.A.) Intervertebral implant with fixation geometry
US8998990B2 (en) 2006-07-24 2015-04-07 DePuy Synthes Products, LLC Intervertebral implant with keel
US20080027547A1 (en) * 2006-07-27 2008-01-31 Warsaw Orthopedic Inc. Prosthetic device for spinal joint reconstruction
KR20090049054A (ko) * 2006-07-31 2009-05-15 신세스 게엠바하 드릴링/밀링 가이드 및 용골 절개 마련 시스템
US20080045968A1 (en) * 2006-08-18 2008-02-21 Warsaw Orthopedic, Inc. Instruments and Methods for Spinal Surgery
US8057545B2 (en) 2006-08-25 2011-11-15 Warsaw Orthopedic, Inc. Revision spacer
US9439948B2 (en) * 2006-10-30 2016-09-13 The Regents Of The University Of Michigan Degradable cage coated with mineral layers for spinal interbody fusion
US8092534B2 (en) 2006-11-16 2012-01-10 Warsaw Orthopedic, Inc. Revision device
US20080154378A1 (en) * 2006-12-22 2008-06-26 Warsaw Orthopedic, Inc. Bone implant having engineered surfaces
US20080161930A1 (en) * 2007-01-03 2008-07-03 Warsaw Orthopedic, Inc. Spinal Prosthesis Systems
US8075593B2 (en) * 2007-05-01 2011-12-13 Spinal Simplicity Llc Interspinous implants and methods for implanting same
CN101854887B (zh) 2007-05-01 2013-09-25 斯百诺辛普利斯提有限责任公司 椎间植入物和用于植入椎间植入物的方法
US8142479B2 (en) * 2007-05-01 2012-03-27 Spinal Simplicity Llc Interspinous process implants having deployable engagement arms
US8864832B2 (en) * 2007-06-20 2014-10-21 Hh Spinal Llc Posterior total joint replacement
FR2916956B1 (fr) 2007-06-08 2012-12-14 Ldr Medical Cage intersomatique,prothese intervertebrale,dispositif d'ancrage et instrumentation d'implantation
US10821003B2 (en) 2007-06-20 2020-11-03 3Spline Sezc Spinal osteotomy
EP2217179A1 (en) 2007-11-16 2010-08-18 Synthes GmbH Low profile intervertebral implant
EP2271377A2 (en) * 2008-03-12 2011-01-12 Nonlinear Technologies Ltd. Spinal implant with structural support and bone interface surfaces formed from uhmwpe
US9192419B2 (en) 2008-11-07 2015-11-24 DePuy Synthes Products, Inc. Zero-profile interbody spacer and coupled plate assembly
WO2010080511A1 (en) 2008-12-18 2010-07-15 4-Web Spine, Inc. Truss implant
US10045860B2 (en) * 2008-12-19 2018-08-14 Amicus Design Group, Llc Interbody vertebral prosthetic device with self-deploying screws
US8425603B2 (en) * 2008-12-22 2013-04-23 Synthes Usa, Llc Orthopedic implant with flexible keel
US8968405B2 (en) * 2009-01-20 2015-03-03 Incite Innovation Llc Interbody fusion device and method of operation
US8349015B2 (en) 2009-02-11 2013-01-08 Howmedica Osteonics Corp. Intervertebral implant with integrated fixation
US20100223935A1 (en) * 2009-03-07 2010-09-09 Donndelinger Thomas M Apparatus and methods for freezing tissue samples for sectioning
US9757164B2 (en) 2013-01-07 2017-09-12 Spinal Simplicity Llc Interspinous process implant having deployable anchor blades
US9861399B2 (en) 2009-03-13 2018-01-09 Spinal Simplicity, Llc Interspinous process implant having a body with a removable end portion
US8945184B2 (en) 2009-03-13 2015-02-03 Spinal Simplicity Llc. Interspinous process implant and fusion cage spacer
WO2010127359A1 (en) * 2009-05-01 2010-11-04 Vg Innovations, Inc. Method and apparatus for spinal interbody fusion
US8617244B2 (en) * 2009-06-17 2013-12-31 DePuy Synthes Products, LLC Intervertebral implant
CN101627931B (zh) * 2009-08-06 2010-12-01 雷伟 一种人工颈椎复合关节
US9700434B2 (en) 2009-08-10 2017-07-11 Howmedica Osteonics Corp. Intervertebral implant with integrated fixation
JP5699353B2 (ja) 2009-09-17 2015-04-08 エルディーアール ホールディング コーポレイション 拡張可能な骨固定部材を有する椎間インプラント
US9033993B2 (en) 2009-11-03 2015-05-19 Howmedica Osteonics Corp. Intervertebral implant with integrated fixation
US8764806B2 (en) 2009-12-07 2014-07-01 Samy Abdou Devices and methods for minimally invasive spinal stabilization and instrumentation
US9480511B2 (en) 2009-12-17 2016-11-01 Engage Medical Holdings, Llc Blade fixation for ankle fusion and arthroplasty
AU2009357504A1 (en) 2009-12-31 2012-07-12 Ldr Medical Anchoring device, intervertebral implant and implantation instrument
US9554909B2 (en) 2012-07-20 2017-01-31 Jcbd, Llc Orthopedic anchoring system and methods
US9421109B2 (en) 2010-01-13 2016-08-23 Jcbd, Llc Systems and methods of fusing a sacroiliac joint
US9333090B2 (en) 2010-01-13 2016-05-10 Jcbd, Llc Systems for and methods of fusing a sacroiliac joint
MX2012008173A (es) 2010-01-13 2012-10-15 Jcbd Llc Sistema de fijacion y fusion de la articulacion sacroiliaca.
US9381045B2 (en) 2010-01-13 2016-07-05 Jcbd, Llc Sacroiliac joint implant and sacroiliac joint instrument for fusing a sacroiliac joint
US20210393409A1 (en) * 2010-07-27 2021-12-23 Tenon Medical, Inc. Systems for Sacroiliac Joint Stabilization
US8480747B2 (en) 2010-08-11 2013-07-09 Warsaw Orthopedic, Inc. Interbody spinal implants with extravertebral support plates
US20120065733A1 (en) * 2010-09-13 2012-03-15 Brian Howard Wieder Inter-vertebral implant having drain cavities therethrough
US9925051B2 (en) 2010-12-16 2018-03-27 Engage Medical Holdings, Llc Arthroplasty systems and methods
WO2012083101A1 (en) 2010-12-17 2012-06-21 Synthes Usa, Llc Methods and systems for minimally invasive posterior arch expansion
WO2012088238A2 (en) 2010-12-21 2012-06-28 Synthes Usa, Llc Intervertebral implants, systems, and methods of use
US8454694B2 (en) 2011-03-03 2013-06-04 Warsaw Orthopedic, Inc. Interbody device and plate for spinal stabilization and instruments for positioning same
EP2720628B1 (en) 2011-06-17 2021-08-11 Jcbd, Llc Sacroiliac joint implant system
US8668723B2 (en) 2011-07-19 2014-03-11 Neurostructures, Inc. Anterior cervical plate
US8845728B1 (en) 2011-09-23 2014-09-30 Samy Abdou Spinal fixation devices and methods of use
US8460388B2 (en) 2011-10-28 2013-06-11 Incite Innovation Llc Spinal interbody device
US9615856B2 (en) 2011-11-01 2017-04-11 Imds Llc Sacroiliac fusion cage
US9254130B2 (en) 2011-11-01 2016-02-09 Hyun Bae Blade anchor systems for bone fusion
US8992619B2 (en) 2011-11-01 2015-03-31 Titan Spine, Llc Microstructured implant surfaces
US9468536B1 (en) 2011-11-02 2016-10-18 Nuvasive, Inc. Spinal fusion implants and related methods
US10188434B2 (en) * 2012-02-17 2019-01-29 The University Of Toledo Hybrid multifunctional posterior interspinous fusion device
US20130226240A1 (en) 2012-02-22 2013-08-29 Samy Abdou Spinous process fixation devices and methods of use
FR2987256B1 (fr) 2012-02-24 2014-08-08 Ldr Medical Dispositif d'ancrage pour implant intervertebral, implant intervertebral et instrumentation d'implantation
EP2822490A4 (en) 2012-03-09 2016-03-02 Si Bone Inc INTEGRATED IMPLANT
US10363140B2 (en) 2012-03-09 2019-07-30 Si-Bone Inc. Systems, device, and methods for joint fusion
US8778026B2 (en) 2012-03-09 2014-07-15 Si-Bone Inc. Artificial SI joint
US8685104B2 (en) 2012-03-19 2014-04-01 Amicus Design Group, Llc Interbody vertebral prosthetic and orthopedic fusion device with self-deploying anchors
US9566165B2 (en) 2012-03-19 2017-02-14 Amicus Design Group, Llc Interbody vertebral prosthetic and orthopedic fusion device with self-deploying anchors
WO2013142480A1 (en) 2012-03-20 2013-09-26 Titan Spine, Llc Friction-fit spinal endplate and endplate-preserving method
US10238382B2 (en) 2012-03-26 2019-03-26 Engage Medical Holdings, Llc Blade anchor for foot and ankle
IN2014DN08676A (ko) 2012-05-04 2015-05-22 Si Bone Inc
US8814912B2 (en) 2012-07-27 2014-08-26 Zimmer Spine, Inc. Bone stabilization member with bone screw retention mechanism
US9198767B2 (en) 2012-08-28 2015-12-01 Samy Abdou Devices and methods for spinal stabilization and instrumentation
CA2889063C (en) 2012-09-25 2021-10-26 4Web, Inc. Programmable implants and methods of using programmable implants to repair bone structures
EP2716261A1 (en) 2012-10-02 2014-04-09 Titan Spine, LLC Implants with self-deploying anchors
US9498349B2 (en) 2012-10-09 2016-11-22 Titan Spine, Llc Expandable spinal implant with expansion wedge and anchor
US9320617B2 (en) 2012-10-22 2016-04-26 Cogent Spine, LLC Devices and methods for spinal stabilization and instrumentation
US9717539B2 (en) 2013-07-30 2017-08-01 Jcbd, Llc Implants, systems, and methods for fusing a sacroiliac joint
US9826986B2 (en) 2013-07-30 2017-11-28 Jcbd, Llc Systems for and methods of preparing a sacroiliac joint for fusion
US9636226B2 (en) 2013-03-15 2017-05-02 4Web, Inc. Traumatic bone fracture repair systems and methods
WO2014145902A1 (en) 2013-03-15 2014-09-18 Si-Bone Inc. Implants for spinal fixation or fusion
US9510872B2 (en) 2013-03-15 2016-12-06 Jcbd, Llc Spinal stabilization system
US9700356B2 (en) 2013-07-30 2017-07-11 Jcbd, Llc Systems for and methods of fusing a sacroiliac joint
US10245087B2 (en) 2013-03-15 2019-04-02 Jcbd, Llc Systems and methods for fusing a sacroiliac joint and anchoring an orthopedic appliance
US11147688B2 (en) 2013-10-15 2021-10-19 Si-Bone Inc. Implant placement
WO2015057866A1 (en) 2013-10-15 2015-04-23 Si-Bone Inc. Implant placement
US9615935B2 (en) 2014-01-30 2017-04-11 Titan Spine, Llc Thermally activated shape memory spring assemblies for implant expansion
US9566169B2 (en) 2014-03-13 2017-02-14 DePuy Synthes Products, Inc. ACIS allograft designs
US9801546B2 (en) 2014-05-27 2017-10-31 Jcbd, Llc Systems for and methods of diagnosing and treating a sacroiliac joint disorder
EP3782586A1 (en) 2014-09-18 2021-02-24 SI-Bone, Inc. Matrix implant
WO2016044731A1 (en) 2014-09-18 2016-03-24 Si-Bone Inc. Implants for bone fixation or fusion
US9867718B2 (en) 2014-10-22 2018-01-16 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
CA2917503A1 (en) 2015-01-14 2016-07-14 Stryker European Holdings I, Llc Spinal implant with fluid delivery capabilities
AU2016200179B2 (en) 2015-01-14 2020-09-17 Stryker European Operations Holdings Llc Spinal implant with porous and solid surfaces
US10028841B2 (en) 2015-01-27 2018-07-24 K2M, Inc. Interbody spacer
US10271958B2 (en) 2015-01-27 2019-04-30 K2M, Inc. Interbody spacer
US10376206B2 (en) 2015-04-01 2019-08-13 Si-Bone Inc. Neuromonitoring systems and methods for bone fixation or fusion procedures
CA2930123A1 (en) 2015-05-18 2016-11-18 Stryker European Holdings I, Llc Partially resorbable implants and methods
US10857003B1 (en) 2015-10-14 2020-12-08 Samy Abdou Devices and methods for vertebral stabilization
US10390955B2 (en) 2016-09-22 2019-08-27 Engage Medical Holdings, Llc Bone implants
US10973648B1 (en) 2016-10-25 2021-04-13 Samy Abdou Devices and methods for vertebral bone realignment
US10744000B1 (en) 2016-10-25 2020-08-18 Samy Abdou Devices and methods for vertebral bone realignment
US10456272B2 (en) 2017-03-03 2019-10-29 Engage Uni Llc Unicompartmental knee arthroplasty
US11540928B2 (en) 2017-03-03 2023-01-03 Engage Uni Llc Unicompartmental knee arthroplasty
EP3381412B1 (en) 2017-03-29 2023-10-18 Stryker European Operations Holdings LLC Spinal implant system
AU2018203667B2 (en) 2017-05-25 2022-09-29 Stryker European Operations Holdings Llc Fusion cage with integrated fixation and insertion features
US11006981B2 (en) 2017-07-07 2021-05-18 K2M, Inc. Surgical implant and methods of additive manufacturing
US10603055B2 (en) 2017-09-15 2020-03-31 Jcbd, Llc Systems for and methods of preparing and fusing a sacroiliac joint
EP3459502A1 (en) 2017-09-20 2019-03-27 Stryker European Holdings I, LLC Spinal implants
WO2019067584A1 (en) 2017-09-26 2019-04-04 Si-Bone Inc. SYSTEMS AND METHODS FOR DECORTICATING SACROILITIC JOINT
US11179248B2 (en) 2018-10-02 2021-11-23 Samy Abdou Devices and methods for spinal implantation
WO2020168269A1 (en) 2019-02-14 2020-08-20 Si-Bone Inc. Implants for spinal fixation and or fusion
US11369419B2 (en) 2019-02-14 2022-06-28 Si-Bone Inc. Implants for spinal fixation and or fusion
US20210145597A1 (en) * 2019-11-20 2021-05-20 United States Government As Represented By The Department Of Veterans Affairs Tissue Engineered Vertebral Discs
JP2023505055A (ja) 2019-11-27 2023-02-08 エスアイ－ボーン・インコーポレイテッド 骨安定インプラント及び仙腸関節を横切る配置方法
US11382761B2 (en) 2020-04-11 2022-07-12 Neurostructures, Inc. Expandable interbody spacer
US11304817B2 (en) 2020-06-05 2022-04-19 Neurostructures, Inc. Expandable interbody spacer
WO2022125619A1 (en) 2020-12-09 2022-06-16 Si-Bone Inc. Sacro-iliac joint stabilizing implants and methods of implantation
US11717419B2 (en) 2020-12-10 2023-08-08 Neurostructures, Inc. Expandable interbody spacer
US20230043823A1 (en) * 2021-08-03 2023-02-09 Warsaw Orthopedic, Inc. Integral graft interbody devices

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
US4714469A (en) * 1987-02-26 1987-12-22 Pfizer Hospital Products Group, Inc. Spinal implant
GB8718627D0 (en) * 1987-08-06 1987-09-09 Showell A W Sugicraft Ltd Spinal implants
JPH01136655A (ja) * 1987-11-24 1989-05-29 Asahi Optical Co Ltd 人工椎間板
US5344654A (en) 1988-04-08 1994-09-06 Stryker Corporation Prosthetic devices having enhanced osteogenic properties
US6210412B1 (en) 1988-06-13 2001-04-03 Gary Karlin Michelson Method for inserting frusto-conical interbody spinal fusion implants
US7452359B1 (en) 1988-06-13 2008-11-18 Warsaw Orthopedic, Inc. Apparatus for inserting spinal implants
US5609635A (en) 1988-06-28 1997-03-11 Michelson; Gary K. Lordotic interbody spinal fusion implants
CA1333209C (en) 1988-06-28 1994-11-29 Gary Karlin Michelson Artificial spinal fusion implants
CA1318469C (en) * 1989-02-15 1993-06-01 Acromed Corporation Artificial disc
DE3911610A1 (de) 1989-04-08 1990-10-18 Bosch Gmbh Robert Kuenstliche bandscheibe
US5112354A (en) 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
FR2659226B1 (fr) * 1990-03-07 1992-05-29 Jbs Sa Prothese pour disques intervertebraux et ses instruments d'implantation.
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
SE9201557D0 (sv) * 1992-05-18 1992-05-18 Astra Ab Joint prosthesis and apparatus for preparing the bone prior to fitting of the prosthesis
DE4328690B4 (de) * 1993-08-26 2006-08-17 SDGI Holdings, Inc., Wilmington Zwischenwirbelimplantat zur Wirbelkörperverblockung und Implantationsinstrument zum Positionieren des Zwischenwirbelimplantats
US5782919A (en) 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US5888222A (en) 1995-10-16 1999-03-30 Sdgi Holding, Inc. Intervertebral spacers
ATE203886T1 (de) * 1995-10-20 2001-08-15 Synthes Ag Zwischenwirbel-implantat
WO1997020526A1 (en) * 1995-12-08 1997-06-12 Bray Robert S Jr Anterior stabilization device
US5709683A (en) * 1995-12-19 1998-01-20 Spine-Tech, Inc. Interbody bone implant having conjoining stabilization features for bony fusion
US5972368A (en) 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US6241771B1 (en) 1997-08-13 2001-06-05 Cambridge Scientific, Inc. Resorbable interbody spinal fusion devices
US5865848A (en) 1997-09-12 1999-02-02 Artifex, Ltd. Dynamic intervertebral spacer and method of use
US6296667B1 (en) 1997-10-01 2001-10-02 Phillips-Origen Ceramic Technology, Llc Bone substitutes
US5824094A (en) * 1997-10-17 1998-10-20 Acromed Corporation Spinal disc
US6139579A (en) 1997-10-31 2000-10-31 Depuy Motech Acromed, Inc. Spinal disc
US6241769B1 (en) 1998-05-06 2001-06-05 Cortek, Inc. Implant for spinal fusion
US6547823B2 (en) * 1999-01-22 2003-04-15 Osteotech, Inc. Intervertebral implant
US6294187B1 (en) 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
US6113638A (en) 1999-02-26 2000-09-05 Williams; Lytton A. Method and apparatus for intervertebral implant anchorage
US6241770B1 (en) * 1999-03-05 2001-06-05 Gary K. Michelson Interbody spinal fusion implant having an anatomically conformed trailing end
US6419704B1 (en) * 1999-10-08 2002-07-16 Bret Ferree Artificial intervertebral disc replacement methods and apparatus
US6592624B1 (en) * 1999-11-24 2003-07-15 Depuy Acromed, Inc. Prosthetic implant element

Also Published As

Publication number Publication date
JP2004516866A (ja) 2004-06-10
EP1576938B1 (en) 2006-08-02
EP1576938A1 (en) 2005-09-21
ATE334644T1 (de) 2006-08-15
ATE296073T1 (de) 2005-06-15
US20040186578A1 (en) 2004-09-23
WO2002030337A2 (en) 2002-04-18
JP4472925B2 (ja) 2010-06-02
DE60111069D1 (de) 2005-06-30
DE60122027D1 (de) 2006-09-14
NZ525798A (en) 2004-10-29
AU1312402A (en) 2002-04-22
US20020049497A1 (en) 2002-04-25
WO2002030337A3 (en) 2002-07-25
AU2002213124A2 (en) 2002-04-22
DE60122027T2 (de) 2007-03-01
EP1326560A2 (en) 2003-07-16
CA2425500C (en) 2010-08-03
AU2002213124B2 (en) 2006-02-23
CA2425500A1 (en) 2002-04-18
EP1326560B1 (en) 2005-05-25
US6743256B2 (en) 2004-06-01
US7163560B2 (en) 2007-01-16

Similar Documents

Publication Publication Date Title
KR20030060910A (ko) 비이식 척수 융합 장치
US6989031B2 (en) Hemi-interbody spinal implant manufactured from a major long bone ring or a bone composite
AU2002213124A1 (en) Graftless spinal fusion device
JP4068644B2 (ja) 少なくとも一つの面取り側面を有するねじ付き体内脊椎融合移植片
US10213309B2 (en) Tissue integration design for seamless implant fixation
US5766253A (en) Spinal fusion device
EP3416592B1 (en) Bone graft
US8491653B2 (en) Intervertebral body fusion cage with keels and implantation methods
AU2003258526B2 (en) Surgical implant
US20050149192A1 (en) Intervertebral body fusion cage with keels and implantation method
US20080208342A1 (en) Spinal implant
JP2004522533A (ja) モジュラー椎骨体間融合インプラント
ATE274889T1 (de) Kegelstumpfförmige spondylodeseimplantate
EP2055267A3 (en) Radiolucent bone graft

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application