KR20020079474A - 활성성분의 방출 연장 - Google Patents
활성성분의 방출 연장 Download PDFInfo
- Publication number
- KR20020079474A KR20020079474A KR1020020018459A KR20020018459A KR20020079474A KR 20020079474 A KR20020079474 A KR 20020079474A KR 1020020018459 A KR1020020018459 A KR 1020020018459A KR 20020018459 A KR20020018459 A KR 20020018459A KR 20020079474 A KR20020079474 A KR 20020079474A
- Authority
- KR
- South Korea
- Prior art keywords
- active ingredient
- meq
- unloaded
- resin
- exchange resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000004480 active ingredient Substances 0.000 title claims abstract description 79
- 238000013265 extended release Methods 0.000 title 1
- 239000003456 ion exchange resin Substances 0.000 claims abstract description 27
- 229920003303 ion-exchange polymer Polymers 0.000 claims abstract description 27
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 238000002360 preparation method Methods 0.000 claims abstract description 6
- 239000002552 dosage form Substances 0.000 claims abstract description 5
- 239000011347 resin Substances 0.000 claims description 52
- 229920005989 resin Polymers 0.000 claims description 52
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 32
- 239000003957 anion exchange resin Substances 0.000 claims description 26
- 239000003729 cation exchange resin Substances 0.000 claims description 17
- -1 Acryl Chemical group 0.000 claims description 14
- 229940023913 cation exchange resins Drugs 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 238000010521 absorption reaction Methods 0.000 claims description 12
- 125000003277 amino group Chemical group 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 10
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 9
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- 229960001193 diclofenac sodium Drugs 0.000 claims description 8
- 125000005395 methacrylic acid group Chemical group 0.000 claims description 8
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 claims description 8
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- 125000000542 sulfonic acid group Chemical group 0.000 claims description 3
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- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 5
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- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 2
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- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical compound C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 description 2
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/07—Processes using organic exchangers in the weakly acidic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/04—Processes using organic exchangers
- B01J41/05—Processes using organic exchangers in the strongly basic form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/04—Processes using organic exchangers
- B01J41/07—Processes using organic exchangers in the weakly basic form
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28244201P | 2001-04-09 | 2001-04-09 | |
| US60/282,442 | 2001-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20020079474A true KR20020079474A (ko) | 2002-10-19 |
Family
ID=23081536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020020018459A Withdrawn KR20020079474A (ko) | 2001-04-09 | 2002-04-04 | 활성성분의 방출 연장 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20020176842A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP1250920A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2003012500A (cg-RX-API-DMAC10.html) |
| KR (1) | KR20020079474A (cg-RX-API-DMAC10.html) |
| TW (1) | TWI242445B (cg-RX-API-DMAC10.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007001300A1 (en) * | 2005-06-28 | 2007-01-04 | Ucb, S.A. | Multiple active drug-resin conjugate |
| US20070149409A1 (en) * | 2003-12-29 | 2007-06-28 | Hi-Cap Formulations Ltd. | Pesticide formulations with substituted biopolymers and organic polymers for improving residual activity, droplet size, adherence and rainfastness on leaves and reduction in soil leaching |
| US8187636B2 (en) | 2006-09-25 | 2012-05-29 | Atlantic Pharmaceuticals, Inc. | Dosage forms for tamper prone therapeutic agents |
| US8568777B2 (en) * | 2007-03-30 | 2013-10-29 | Monosol Rx, Llc | Packaged film dosage unit containing a complexate |
| AU2009202778B2 (en) * | 2008-07-11 | 2014-05-08 | Commonwealth of Australia as represented by and acting through the Department of Climate Change, Energy, the Environment and Water | Improved baiting method and composition |
| US10874741B2 (en) * | 2017-08-28 | 2020-12-29 | Spectrix Therapeutics, LLC | Compound to treat Sjogren's syndrome |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4252790A (en) * | 1974-10-23 | 1981-02-24 | Interx Research Corporation | Method for treating gastric ulcer-prone patients |
| HU176215B (en) * | 1978-01-27 | 1981-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1 |
| CH655507B (cg-RX-API-DMAC10.html) * | 1983-01-12 | 1986-04-30 | ||
| US4911920A (en) * | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US5184630A (en) * | 1992-04-06 | 1993-02-09 | Uop | Hair deodorizing compositions and process for using |
| AU666957B2 (en) * | 1992-08-28 | 1996-02-29 | Alcon Laboratories, Inc. | Use of certain anionic surfactants to enhance antimicrobial effectiveness of ophthalmic compositions |
| ATE181672T1 (de) * | 1993-04-28 | 1999-07-15 | Takeda Chemical Industries Ltd | Geschmacksmaskierte feste zubereitung und verfahren zur herstellung |
| GB9402029D0 (en) * | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| WO1995027530A1 (en) * | 1994-04-08 | 1995-10-19 | Alza Corporation | Electrotransport system with ion exchange competitive ion capture |
| CA2367490A1 (en) * | 1999-04-13 | 2000-10-19 | Naruhito Higo | Iontophoresis device |
-
2002
- 2002-03-26 US US10/107,288 patent/US20020176842A1/en not_active Abandoned
- 2002-04-01 TW TW091106509A patent/TWI242445B/zh not_active IP Right Cessation
- 2002-04-04 KR KR1020020018459A patent/KR20020079474A/ko not_active Withdrawn
- 2002-04-08 EP EP02252512A patent/EP1250920A1/en not_active Withdrawn
- 2002-04-09 JP JP2002106425A patent/JP2003012500A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20020176842A1 (en) | 2002-11-28 |
| JP2003012500A (ja) | 2003-01-15 |
| EP1250920A1 (en) | 2002-10-23 |
| TWI242445B (en) | 2005-11-01 |
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| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20020404 |
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| PC1203 | Withdrawal of no request for examination | ||
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