KR20020020142A - Oriental drug formulation convient to use and method therefor - Google Patents

Oriental drug formulation convient to use and method therefor Download PDF

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KR20020020142A
KR20020020142A KR1020000053343A KR20000053343A KR20020020142A KR 20020020142 A KR20020020142 A KR 20020020142A KR 1020000053343 A KR1020000053343 A KR 1020000053343A KR 20000053343 A KR20000053343 A KR 20000053343A KR 20020020142 A KR20020020142 A KR 20020020142A
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herbal medicine
herbal
cut
honey
jelly
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윤기평
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윤기평
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

PURPOSE: Provided are easy dose herbal remedies which block a contact with air and consequently have an improved storageability and their manufacturing method. CONSTITUTION: The manufacturing method of easy dose herbal remedies comprises the steps of: preparing medicinal herbs into powdery or extract type of preparations; adding honey or glutinous rice glue to the preparations then kneading them into a thin dough; forming it into a various shapes; adding flavoring agents or coloring agents thereto; and coating the prepared preparations with coating materials selected from caramel, chocolate and jelly.

Description

복용간편한 한약제제 및 그 제조방법{ORIENTAL DRUG FORMULATION CONVIENT TO USE AND METHOD THEREFOR}ORIENTAL DRUG FORMULATION CONVIENT TO USE AND METHOD THEREFOR}

본 발명은 복용간편한 한약 제제 및 그 제제방법에 관한 것으로서, 더욱 상세하게는 특정 질환을 치료하기 위해 사용되는 통상의 한약재에 꿀 또는 찹쌀 풀 등의 부재료를 첨가하여 원하는 모양으로 잘라내거나 특정 형태로 성형하고 젤리 등의 피막제를 입혀 복용 및 휴대가 간편하고, 한약제제와 공기와의 직접적인 접촉을 차단하여 장기간 보존이 용이 할 뿐만 아니라 투여량 조절도 용이하여 사용성이 뛰어난 신규한 한약제제에 관한 것이다.The present invention relates to a convenient Chinese medicine preparation and a method for preparing the same, and more particularly, to add a subsidiary material such as honey or glutinous rice paste to a conventional Chinese medicine used to treat a specific disease, and cut it into a desired shape or to form a specific shape The present invention relates to a novel herbal medicine which is easy to take and carry by coating a coating agent such as jelly, and is easy to use for long-term storage as well as easy dosage adjustment by blocking direct contact between the herbal medicine and air.

종래 한약의 제제화는 환모양의 한약을 제조하거나 한약재를 달여서 탕의 형태로 제조하는 것이 일반적이었다. 따라서, 한약의 복용방법에 있어서도 환모양의 한약을 직접 씹어서 먹거나 탕을 약 사발이나 컵에 부은 후 음용하는 것이 일반적인 방법이었다. 또한, 최근에는 한약재를 달여서 탕의 형태로 제조된 한약을 비닐재로 된 파우치에 진공 밀봉하여 장기간 보존할 수 있고, 휴대할 수도 있는 한약 제제 및 그 제제방법들이 소개되고 있었다.Conventional Chinese medicine formulations have generally been made in the form of tang-shaped Chinese medicine or decoction of Chinese medicine. Therefore, in the method of taking herbal medicine, it was a common method to chew a ring-shaped Chinese medicine directly, or pour it in a bowl or cup of medicine and drink it. In addition, recently, herbal medicines prepared in the form of baths by decoction of herbal medicines are vacuum-sealed in pouches made of vinyl material, which can be stored for a long time and can be carried.

그러나, 상기 제제는 한약을 직접 음용하는 것으로서 맛이 쓰고 불편하여 심리적으로 한약에 대한 거부감이 있었다.However, the preparation is a direct drinking of the herbal medicine taste and uncomfortable, there was a psychological rejection of the herbal medicine.

대한민국 특허 제219439호에는 동결 건조된 미분쇄된 동물성 생약인 녹용분말에 불활성 미분성 흡착제로서 스테아린산 마그네슘을 첨가한 후 캅셀에 충전하는 녹용 캅셀제에 관한 것이 개시되어 있다.Korean Patent No. 219439 discloses a antler capsule which is filled with a capsule after adding magnesium stearate as an inert fine powder adsorbent to a antler powder, which is a lyophilized animal medicine that is freeze-dried.

그러나, 상기한 액상 한약 제제의 경우 제조과정이 복잡하고, 휴대 및 복용이 불편하다는 문제점이 있었다. 액상 한약 제제를 파우치에 넣어서 휴대성을 개선한 경우에도 복용할 때 마다 액상 한약 제제를 적당한 온도로 데워야 하고, 진공밀봉된 파우치는 개봉하기가 불편하다는 문제점이 있었다.However, in the case of the above-mentioned liquid herbal medicine preparation, there is a problem in that the manufacturing process is complicated, and carrying and taking are inconvenient. Even when the portability of the liquid Chinese medicine preparation is improved, the liquid Chinese medicine preparation should be warmed to an appropriate temperature every time it is taken, and the vacuum-sealed pouch has a problem in that it is inconvenient to open.

또한, 상기 녹용 갑셀제의 경우에도 환자에게 의약품이라는 인상의 관념을 여전히 갖게 한다는 문제점이 있었다.In addition, in the case of the antler oxelase, there was a problem in that the patient still has the notion of an impression of medicine.

본 발명은 상기와 같은 문제점을 해결하기 위하여 복용 및 휴대가 편리하고,한약재 특유의 특성을 중화시키면서도 한약 제제 자체에 심미적 감각을 가미하여 한약제제를 복용할 때의 거부감을 제거하여 주는 사용하기 편리한 한약 제제 및 그 제조방법을 제공하는 것을 목적으로 한다.The present invention is convenient to take and carry in order to solve the above problems, while neutralizing the peculiar characteristics of the herbal medicine, convenient Chinese medicine to remove the rejection when taking the herbal medicine by adding an aesthetic sense to the herbal medicine itself An object of the present invention is to provide a formulation and a method for producing the same.

도 1은 본 발명에 따른 한약제제의 층상구조를 나타내는 도면이다.1 is a view showing a layered structure of a herbal medicine according to the present invention.

<도면의 주요 부분에 대한 부호의 설명><Explanation of symbols for the main parts of the drawings>

10 : 피막 20 : 한약재10: film 20: herbal medicine

본 발명 사용하기 편리한 한약제제는 처방에 요구되는 한약재들을 직접 분말화 하거나 또는 추출물 형태의 제제로 만든 후 꿀 또는 찹쌀 풀 등으로 반죽하여 두께가 얇은 반죽으로 펴서 여러 가지 모양으로 잘라 내고, 여기에 한약재 고유의 특성을 다르게 느낄 수 있도록 하는 물질을 첨가한 피막제로 피막을 입히는 것을 특징으로 한다.Herbal medicines convenient to use the present invention powder the herbal medicines required for the prescription or made in the form of extract form and then kneaded with honey or glutinous rice paste, etc. to spread into thin dough and cut into various shapes, here the herbal medicines It is characterized by coating the film with a coating agent added with a substance that makes it possible to feel its own characteristics differently.

즉, 본 발명 복용간편한 한약제제의 제조방법은 특정 질병을 치료 또는 예방하기 위한 처방에 요구되는 통상의 한약재들을 직접 분말화 하거나 또는 추출물 형태의 제제로 제조하는 단계;That is, the method for preparing a convenient Chinese medicine preparation of the present invention comprises the steps of directly powdering or preparing an extract form of a conventional herbal medicine required for prescription for treating or preventing a specific disease;

상기 제제에 꿀 또는 찹쌀 풀 등을 첨가하여 두께가 얇은 반죽으로 펴서 여러 가지 모양으로 잘라 내거나 특정 모양으로 성형하는 단계;Adding honey or glutinous rice paste to the formulation, and spreading it into a thin dough to cut it into various shapes or to form a specific shape;

상기 성형물에 식용향료 및/또는 식용색소 물질을 첨가하는 단계; 및Adding an edible flavor and / or food coloring substance to the molding; And

상기 단계에 의해 제조된 한약제제에 카라멜, 초코렛 및 젤리로 구성된 군으로부터 선택된 피막제로 피막을 입히는 단계를 포함하는 것을 특징으로 한다.It is characterized in that it comprises the step of coating the film with a coating agent selected from the group consisting of caramel, chocolate and jelly in the herbal preparation prepared by the above step.

본 발명의 상기 처방에 요구되는 한약재는 통상의 한방지식에 근거하여 특정 질환을 처리하기 위해 사용되는 통상의 한약재료, 예컨대 정향(丁香), 세신(細辛),사상자(蛇床子), 용골(龍骨), 해표초(海표초), 고반(故礬), 호초(胡椒)로 구성되는 원앙정, 흑당(黑糖), 진피(陳皮), 창출(蒼朮), 후박(厚朴), 산사(山査), 중조(重曹), 향부자(香附子), 신곡(神曲), 맥아(麥芽), 양강(良干), 건강(乾干), 현호색(玄胡索), 백두구(白豆久), 초두구(草豆久), 육두구(肉豆久), 자단향(紫壇香), 목향(木香), 계내금(鷄內金), 대황(大黃), 호초(胡椒), 지실(枳實), 삼릉(三稜), 봉출(蓬朮), 계피(桂皮), 정향(丁香), 감초(甘草), 용뇌(龍腦), 박하뇌(薄荷腦)로 구성되는 소화제, 백복령(白茯笭), 숙지황(熟地黃), 인삼(人蔘), 사인(砂仁), 애엽(艾葉, 쑥), 꿀로 등의 통상의 동물성, 식물성, 및 광물성 한약재료를 모두 포함할 수 있다.The herbal medicine required for the above-described prescription of the present invention is a conventional herbal medicine used for treating a specific disease on the basis of a conventional Korean herbal formula, such as cloves, sessins, sandals, keel ( Mandarin duck, seaweed vinegar, Goban, Hocho, Hoang-jeong, Black sugar, Dermis, Cultivation, Thick leaf, Sansa ), Chinese zodiac, Hyangbuja, Shingok, Malt, Yanggang, Health, Hyun-ho-ji, Baekdu-gu, Chodu-gu (草 豆 久), nutmeg, rosewood incense, mokyang (木香), kyegeumgeum, rhubarb, hocho, jisil , Sanreung (三 삼), Bulgogi (계), Cinnamon (정), Clove (丁香), Licorice (甘草), Dragon brain (龍 腦), Peppermint brain (薄荷 腦), Baekbokyeong (白 茯 笭) Ordinary animal, vegetable, etc., such as ripening sulfur, mature ginseng, ginseng, sine, larvae, honey It may include all of the physical properties of herbal ingredients.

상기 성분들을 조합한 어떠한 한약제제도 본 발명 방법에 따른 특정 모양으로 성형될 수 있으며, 바람직한 실시예에 따르면 원앙정, 소화제, 생리통 치료제 등의 복용간편한 한약제제의 제조방법 및 그 효과가 제공된다.Any herbal combination combining the above components may be molded into a specific shape according to the method of the present invention, and according to a preferred embodiment, a method for preparing a simple herbal medicine such as mandarin tablets, digestive agents, menstrual pain treatments, and the like is provided.

본 발명의 상기 모양은 예컨대, 껌과 같은 길다란 사각형모양, 별모양, 원형, 또는 하트 모양일 수 있다. 그러나, 본 발명이 이들 모양에 한정되는 것은 아니고, 다른 복용에 있어서 편리성을 주는 것이면 통상의 어떠한 입체적 형상으로든 성형될 수 있다.The shape of the present invention may be, for example, a long rectangular, star, circular, or heart-shaped like gum. However, the present invention is not limited to these shapes, and may be molded into any conventional three-dimensional shape as long as it provides convenience in other doses.

본 발명의 상기 한약재 고유의 특성을 다르게 느낄 수 있도록 하기 위하여 식용향료 및/또는 식용색소 를 첨가할 수 있다. 상기 식용향료에는 바닐라 향(vanilla flavor), 초코렛 향, 허브향, 바나나, 딸기향, 사과향 등이 선택되어질 수 있다. 상기 식용색소에는 심황, 치자, 사프란 또는 엽록소와 같은 천연 식용색소 혹은 β-카로틴, 수용성 안나토, 황산구리와 같은 식용 인공색소일 수 있다. 그러나, 본 발명 상기 첨가물질은 이들 물질에 한정되는 것은 아니고, 약효와 상관없는 특성으로서 한약재 고유의 특성을 다르게 느낄 수 있도록 하는 물질로서 한약재 특유의 쓴맛, 냄새 등의 심리적 거부감을 주는 특성을 중화시킬 수 있는 물질 또는 복용 가식감을 돋구어 줄 수 있는 색소들로 통상적으로 당업계에서 공지되어 있는 물질들일 수 있다.In order to feel different characteristics of the herbal medicines of the present invention may be added food flavoring and / or food coloring. Vanilla flavor, chocolate flavor, herbal flavor, banana, strawberry flavor, apple flavor, etc. may be selected as the edible flavor. The food coloring may be a natural food coloring such as turmeric, gardenia, saffron or chlorophyll or an food coloring such as β-carotene, water soluble anato, copper sulfate. However, the additive material of the present invention is not limited to these substances, and as a substance that does not relate to the efficacy of the medicinal herbs, it is possible to neutralize the psychological rejection characteristics such as bitterness, smell, etc. It can be a substance that is commonly known in the art as a substance that can be used or pigments that can enhance the sense of taking.

본 발명의 상기 피막제는 예를 들면, 카라멜 또는 젤라틴 등일 수 있으며, 상기 피막제는 성형된 특정 형태의 한약제 겉을 코팅하는데 이용될 수 있다.The encapsulant of the present invention may be, for example, caramel or gelatin, and the encapsulant may be used to coat a specific form of the herbal medicine.

이하, 실시예를 통하여 본 발명을 보다 상세하게 설명한다. 그러나, 이들 실시예들은 예시적인 목적일 뿐 본 발명이 이들 실시예에 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail with reference to Examples. However, these examples are for illustrative purposes only, and the present invention is not limited to these examples.

[실시예 1]Example 1

본 발명에 따른 원앙정 제제Mandarin duck preparation according to the present invention

본 실시예에서는 여성의 질 내에 삽입되었을 때 성적 쾌감을 증가시키는 약효를 갖는 원앙정을 본 발명의 방법에 따라 제조하였다.In this example, a mandarin tablet was prepared according to the method of the present invention which has the effect of increasing sexual pleasure when inserted into the vagina of a woman.

원앙정의 처방 구성은 다음 표 1과 같다.The composition of the formula is as shown in Table 1.

표 1. 원앙정의 처방 구성Table 1. Prescription Composition

한약재명Chinese medicine renaming 정향cloves 세신Sesin 사상자Casualties 용골keel 해표초Haechocho 고반Govan 호초Lake 중량부Parts by weight 22 22 22 22 22 22 1One

표 1에 나타낸 원앙정의 처방에 포함되는 한약재들을 분쇄하여 분말화 하였다. 여기에 찹쌀 풀를 첨가하고 반죽을 만들었다. 반죽된 한약재(20)들을 얇은 두께로 폈다. 얇게 편 반죽을 건조 무게 약 0.5g이 되도록 직사각형(또는 하트) 모양으로 잘랐다. 여기에 식용 향료 또는 색소가 첨가된 물질로 피막(10)을 입혔다.Chinese herbal medicines included in the formulation of Won Ang Jung shown in Table 1 were ground and powdered. Glutinous rice paste was added to this and dough was made. Kneaded herbal medicines 20 were thinned to a thin thickness. The thinly sliced dough was cut into rectangular (or heart) shapes to a dry weight of about 0.5 g. The film 10 was coated with a substance to which an edible flavor or a pigment was added.

상기와 같이 제조된 사용하기 편리한 원앙정 제제를 총 156명에게 임상실험을 하였다. 임상실험의 방법은 상기의 제제를 성교 직전에 상대 파트너가 아는 상태에서 질 내에 삽입하거나 상대 파트너가 모르는 상태에서 질 내에 삽입하고 그 효과를 살펴 보았다.A total of 156 clinical trials were conducted with the easy-to-use mandarin tablets prepared as described above. In the clinical trial method, the above-described preparation was inserted into the vagina immediately before sexual intercourse in the state of knowing the other partner or in the vagina without the knowing of the partner and examined its effect.

실험 결과는 다음 표 2 및 표 3에 나타낸 것 바와 같다.The experimental results are as shown in the following Table 2 and Table 3.

표 2. 원앙정 제제를 삽입하는 주체가 남자일 경우의 상대 여성의 반응Table 2. Responses of females when the subject inserts the mansard

성적 쾌감 정도Sexual pleasure 불쾌discomfort 보 통usually 쾌감 증가Increased pleasure 상대 남성이 안 경우(37명)If the other male is not known (37) 99 88 1313 상대 남성이 모른 경우(61명)If you don't know your partner (61) 66 1717 3838

표 3. 원앙정 제제를 삽입하는 주체가 여자일 경우의 상대 남성의 반응Table 3.Relative response of male when the subject inserting the manipulator

성적 쾌감 정도Sexual pleasure 불쾌discomfort 보통usually 쾌감 증가Increased pleasure 상대 남성이 안경우(33명)The other man is glasses (33) 99 1010 1414 상대 남성이 모른 경우(32명)If the other man doesn't know (32) 33 55 2424

표 2 및 3에 나타낸 바와 같이, 상대방 상대방 파트너가 모르게 했을 경우에 효과가 높으며 알게 사용한 경우에는 질 내 이물질이 삽입되었다는 것에 대한 심리적인 부담감으로 인하여 효과가 감소하였다.As shown in Tables 2 and 3, the effect was high when the other partner did not know, and when used, the effect was reduced due to the psychological burden on the insertion of foreign substances in the vagina.

표 4는 본 발명에 의한 원앙정을 질 내에 삽입하였을 때에 연령별에 따른 만족도를 나타낸 결과이다.Table 4 is a result showing the satisfaction according to age when the mandrel of the present invention is inserted into the vagina.

표 4. 원앙정에 대한 연령별 만족도Table 4. Satisfaction by Age for Wonang Jeong

연령age 20대20's 30대30 spaces 40대40 spaces 50대50 spaces 만족도(%)satisfaction(%) 3030 5050 7575 9090

표 4에 나타낸 바와 같이, 연령이 증가할수록 본 발명에 의한 원앙정제제 대하여 만족도가 증가하였다.As shown in Table 4, as age increases, satisfaction with the mandarin tablet according to the present invention increases.

[실시예 2]Example 2

본 발명에 따른 소화제 제제Extinguishing agent preparation according to the present invention

본 실시예에서는 다음과 같은 처방구성을 갖는 한약재(20)로 된 소화제를 본 발명의 방법에 따라 제조하였다.In the present embodiment was prepared according to the method of the present invention a fire extinguishing agent of the herbal medicine 20 having the following composition.

한약으로 된 소화제의 처방구성은 다음 표 5에 나타낸 바와 같다.Prescription composition of the Chinese medicine digestive agent is shown in Table 5 below.

표 5. 소화제의 처방구성Table 5. Composition of Extinguishing Media

한약재명Chinese medicine renaming 흑당Brown sugar 진피dermis 창출Creation 후박Thick 산사Sansa 중조baking soda 사인sign 향부자Hyangbuja 신곡new song 맥아malt 중량부Parts by weight 1515 1010 1010 1010 1010 1010 77 77 77 77

표 5. (계속)Table 5. (continued)

한약재명Chinese medicine renaming 양간Bilateral 건간Tendon 현호색Corydalis 백두구Baekdu-gu 초두구Headlights 육두구nutmeg 자단향Rosewood 목향elecampane 계내금System 대황rhubarb 중량부Parts by weight 77 77 77 55 55 55 55 55 55 33

표 5. (계속)Table 5. (continued)

한약재명Chinese medicine renaming 호초Lake 지실Basement 삼릉Samneung 봉출Ejection 계피cinnamon 정향cloves 감초licorice 용뇌Brain 박하뇌Peppermint brain 중량부Parts by weight 33 22 22 22 22 22 22 1One 1One

상기 표 5에 나타낸 처방구성을 혼합한 후 꿀을 첨가하여 반죽하였다. 이들 반죽을 약 3.75g의 구형으로 빚어 내었다. 여기에 박하향을 첨가한 젤리로 피막(10)을 입혔다.After mixing the formulation shown in Table 5, the dough was added by adding honey. These doughs were formed into a sphere of about 3.75 g. The film 10 was coated with jelly to which peppermint flavor was added.

상기와 같이 제조된 소화제 제제를 식후 5분에 2환씩 1일 2 내지 3회 복용시키고, 이를 1 내지 2일간 계속하도록 하도록 하거나, 식후 5분에 1환씩 1일 2 내지 3회 복용시키고, 이를 3개월간 계속하도록 하였다.The digestive agent prepared as described above is taken 2 to 3 times a day for 2 minutes at 5 minutes after meals, so that it can be continued for 1 to 2 days, or 2 to 3 times per day at 5 minutes after meals, and 3 The month was continued.

표 6, 7에 본 실시예에 따른 소화제 제제의 임상시험 결과를 나타내었다.Tables 6 and 7 show the results of clinical trials of the extinguishing agent preparations according to this example.

표 6. 과식, 급성위염 등으로 인한 위완통(胃脘痛), 소화불량(消化不良), 위민(胃閔) 등의 증상을 수반할 때 복용.Table 6. Taken when accompanied by symptoms such as gastric pain, indigestion, gastric problems due to overeating, acute gastritis, etc.

증상Symptom 증상악화Worsening symptoms 그저 그렇다.so so. 증상 호전Symptom improvement 불편한 증상 대부분 소실Most discomforts disappear 인원personnel 23명(5%)23 people (5%) 60명(13%)60 people (13%) 263명(57%)263 people (57%) 116명(25%)116 people (25%)

표 7. 만성 위염, 위하수, 위산과다 등으로 인한 제반 증상을 수반할 때 복용.Table 7. Taken when accompanied with symptoms of chronic gastritis, gastric sewage, excessive stomach acid, etc.

증상Symptom 증상악화Worsening symptoms 그저 그렇다.so so. 증상 호전Symptom improvement 불편한 증상 대부분 소실Most discomforts disappear 인원personnel 4명(3%)4 people (3%) 8명(6%)8 people (6%) 80명(60%)80 people (60%) 40명(31%)40 people (31%)

표 6에 나타낸 바와 같이, 과식, 급성위염 등으로 인한 위산통, 소화불량, 위인 등의 증상이 수반하는 경우 복용하였을 때는 약 82%가 증상호전 이상의 반응을 보였다. 이 경우에도 약 5%의 증상약화가 관찰되었으나 이 경우에도, 급성 위경련 환자가 복용하였을 때 구토증세로 환자가 증세가 더 악화되었다고 느꼈을 뿐 실제로 병세가 더 심해진 것은 아니었다.As shown in Table 6, when symptoms such as stomach acid pain, indigestion, and gastrointestinal tract caused by overeating, acute gastritis, and so on, about 82% showed improvement in symptoms. In this case, about 5% of symptom attenuation was observed, but even in this case, the patient felt worsened due to vomiting when the acute gastric spasms were taken.

표 7에 나타낸 바와 같이, 만성 위염, 위하수, 위산과다 등으로 인한 제반 증상을 수반하는 경우 복용하였을 때는 약 91%가 증상 호전이상의 반응을 보였다. 이 경우에도 약 3%의 증상악화가 관찰되었으나, 위암 환자, 위십이지장 궤양 환자의 경우에 해당하는 것으로 여겨진다.As shown in Table 7, about 91% of the patients responded to symptomatic improvement when they were accompanied with symptoms related to chronic gastritis, gastric drainage, and excessive acidity. In this case, about 3% of symptomatic worsening was observed, but it is considered to be applicable to gastric cancer patients and gastroduodenal ulcer patients.

[실시예 3]Example 3

본 발명에 따른 생리통 치료제 제제Formula for treating dysmenorrhea according to the present invention

본 실시예에서 제조한 생리통 치료제 제제의 처방구성은 다음 표 8에 나타낸 바와 같다.The formulation of the preparation for treating dysmenorrhea in this embodiment is shown in Table 8 below.

표 8. 생리통 치료제 제제의 처방구성Table 8. Prescription Composition of Medications for Menstrual Pain

한약재명Chinese medicine renaming 백복령Baikyeongryeong 숙지황Hungjiwang 인삼Ginseng 사인sign 애엽(쑥, )Love Leaf honey 중량부Parts by weight 66 33 33 1One 1One 66

먼저, 상기 표 8에 나타낸 처방구성 중에서 백복령, 인삼, 사인, 애엽을 혼합하여 분말화 하였다. 한편, 숙지황을 물과 함께 끓여 반죽한 후 고운 채로 걸렀다. 다음으로, 상기의 백복령, 인삼, 사인 애엽의 혼합 분말과 걸러진 숙지황을 함께 섞고 여기에 꿀을 첨가한 후 반죽하였다. 위와 같이 반죽된 것을 만 4일 동안중탕(重湯)하여 찐다. 중탕하여 얻어진 약제를 건조 시킨 후 다시 분말화하여 꿀과 함께 반죽하였다. 이것을 얇게 편 후 하트모양으로 잘라 내고 여기에 바닐라향이 가미된 젤리로 피막(10)을 입혀 한약으로 된 생리통 치료제 제제를 완성하였다.First, in the formulations shown in Table 8, Baekbok-ryeong, ginseng, sine, and leaves were mixed and powdered. On the other hand, the sucrose was boiled with water, kneaded and filtered. Next, the mixed powder of Baekbokryeong, ginseng, sine leaf and the filtered Sukjihwang were mixed together and kneaded after adding honey thereto. Knead as above and steamed for 4 days in heavy water. The medicine obtained by hot water was dried and then powdered and kneaded with honey. After thinly cutting it, it was cut into a heart shape and coated with a film (10) with a vanilla flavored jelly to complete a medicine for treating menstrual pain.

상기와 같이 제조된 생리통 치료제 제제를 임상실험하였다. 임상실험의 방법은 약 7.5g을 1일 2회 식간에 복용시키고, 이를 2개월 동안 계속하였다.Clinical trials were carried out on the preparation for treating menstrual pain. The method of the clinical trial was taking about 7.5 g twice daily between meals and continued for 2 months.

표 9에 본 실시예에 따른 생리통 치료제 제제의 임상시험 결과를 나타내었다.Table 9 shows the results of clinical trials of the agent for treating dysmenorrhea according to this example.

표 9. 생리통 치료제 제제의 임상실험 결과Table 9. Results of Clinical Trials for Menstrual Pain Therapeutics

증상악화Worsening symptoms 증상 변화없음No change in symptoms 증상 호전Symptom improvement 증상 크게 호전Significantly improve symptoms 미혼녀(81명)Unmarried Women (81) 00 8(10%)8 (10%) 22(27%)22 (27%) 51(63%)51 (63%) 기혼녀(33명)Married Women (33) 00 7(21%)7 (21%) 16(48%)16 (48%) 11(31%)11 (31%)

상기 표 9에 나타낸 바와 같이, 미혼녀의 경우 본 실시예의 생리통 치료제 제제를 복용하였을 때 90%가 증상 호전이상의 반응을 보였다. 반면, 기혼녀의 경우는 79%가 증상 호전이상의 반응을 보였다. 이는 미혼녀의 경우는 단순히 자궁발육부전, 하초허냉 등의 원인으로 효과가 좋았으나, 기혼녀의 경우에는 자궁내의 여러 가지 염증성 질환, 자궁 근종 등의 지질적 병변에 의한 경우가 상당수 존재하였기 때문에 미혼녀에 비하여 상대적으로 치료율이 낮다고 여겨진다. 한편, 복용으로 효과를 본 경우 6개월 이내에 통증이 재발할 확률은 약 25% 정도이었다.As shown in Table 9 above, 90% of unmarried women responded to symptom improvement. In contrast, 79% of married women responded to symptom improvement. In the case of unmarried women, it was effective due to uterine dysfunction and hypoxia, but in married women, there were many cases of geological lesions such as inflammatory diseases and uterine fibroids. It is considered that the treatment rate is relatively low. On the other hand, if the effects were taken by taking the chance of recurrence of pain within 6 months was about 25%.

본 발명에 따르면, 한약재로 된 제제를 복용하기에 편리할 뿐만아니라, 한약제제와 공기와의 직접적인 접촉을 차단하여 장기간 보존이 용이하고 휴대 및 복용량을 조절하기에도 편리하다.According to the present invention, not only is it convenient to take the preparation of the herbal medicine, it is also convenient for long-term storage and convenient to carry and adjust the dosage by blocking direct contact between the herbal medicine and the air.

또한, 발명에 따르면, 한약제제에서 미각, 후각 및 시각 등의 오감을 통하여 미감을 일으킬 수 있게 하는 식용향료나 식용색소를 포함하고 있기 때문에 본 한약제제를 복용하는 환자에게 심리적 안정감을 준다.In addition, according to the present invention, since the herbal medicine contains an edible flavor or food coloring that can cause aesthetics through the five senses such as taste, smell and sight, it gives psychological stability to the patient taking the herbal medicine.

Claims (4)

특정 질병을 치료 또는 예방하기 위한 처방에 요구되는 통상의 한약재들을 직접 분말화 하거나 또는 추출물 형태의 제제로 만든 후 꿀 또는 찹쌀 풀 등으로 반죽하여 두께가 얇은 반죽으로 펴서 여러 가지 모양으로 잘라 내거나 성형하고, 여기에 식용향료 및/또는 식용색소 물질을 첨가하고, 카라멜, 초코렛, 및 젤리로 구성된 군으로부터 선택된 피막제로 피막을 입힌 복용간편한 한약제제.Ordinary herbal medicines required for the treatment or prevention of specific diseases can be directly powdered or made into extract-type preparations, and then kneaded with honey or glutinous rice paste to be cut into thin doughs and cut or shaped into various shapes. A simple herbal medicine dosed with an edible flavor and / or food coloring substance and coated with a coating agent selected from the group consisting of caramel, chocolate, and jelly. 제1항에 있어서, 상기 모양은 껌, 별모양, 하트 모양 또는 구형인 것을 특징으로 하는 복용간편한 한약제제.The method of claim 1, wherein the shape is gum, star, heart-shaped or spherical easy to take, characterized in that the spherical. 특정 질병을 치료 또는 예방하기 위한 처방에 요구되는 통상의 한약재들을 직접 분말화 하거나 또는 추출물 형태의 제제로 제조하는 단계;Directly powdering or preparing an extract form of a conventional herbal medicine required for a prescription for treating or preventing a specific disease; 상기 제제에 꿀 또는 찹쌀 풀 등을 첨가하여 두께가 얇은 반죽으로 펴서 여러 가지 모양으로 잘라 내거나 특정 모양으로 성형하는 단계;Adding honey or glutinous rice paste to the formulation, and spreading it into a thin dough to cut it into various shapes or to form a specific shape; 상기 성형물에 식용향료 및/또는 식용색소 물질을 첨가하는 단계; 및Adding an edible flavor and / or food coloring substance to the molding; And 상기 단계에 의해 제조된 한약제제에 카라멜, 초코렛 및 젤리로 구성된 군으로부터 선택된 피막제로 피막을 입히는 단계를 포함하는 것을 특징으로 하는 복용간편한 한약제제의 제조방법.A method of preparing a simple herbal medicine, characterized in that it comprises coating the film with a coating agent selected from the group consisting of caramel, chocolate and jelly in the herbal preparation prepared by the step. 제3항에 있어서, 상기 모양은 사각형모양, 별모양, 하트 모양 또는 구형인 것을 특징으로 하는 복용간편한 한약제제의 제조방법.4. The method of claim 3, wherein the shape is rectangular, star, heart or spherical.
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Cited By (4)

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Publication number Priority date Publication date Assignee Title
KR20030012714A (en) * 2001-08-04 2003-02-12 양상철 a making method for growth food
KR20030060124A (en) * 2002-01-07 2003-07-16 김준원 Manufacturing method of herb remedy
KR20040024779A (en) * 2002-09-16 2004-03-22 김종수 Food composition
KR100441630B1 (en) * 2001-03-20 2004-07-27 오성천 Functional Yanggaeng Composition Containing Extracts of Soft Core of Antlers

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JPH08140626A (en) * 1994-11-18 1996-06-04 Power Shifuto:Kk Instant medicinal food material
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KR20010084077A (en) * 2000-02-23 2001-09-06 김혁 Method to incrassate korean medical compositions and korean medical jelly incrassated by it
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US4937076A (en) * 1984-08-10 1990-06-26 Combe Incorporated Chewable aspirin and buffering material tablet and method for producing same
JPS63238021A (en) * 1987-03-25 1988-10-04 Tsurui Yakuhin Kogyo Kk Herb medicine in solid form
JPH071042U (en) * 1993-04-23 1995-01-10 有限会社前田産業 Ginseng triangle capsule
JPH07267977A (en) * 1994-03-31 1995-10-17 I T Bi S:Kk Glycoside from fruit essence of panax shinseng, production thereof, production of health food thereform
JPH08140626A (en) * 1994-11-18 1996-06-04 Power Shifuto:Kk Instant medicinal food material
KR100254805B1 (en) * 1997-07-01 2000-08-01 이용원 Chewable tablet and method of preparation thereof
KR19990065336A (en) * 1998-01-12 1999-08-05 김강권 Production method of one-sided jadeite jade and its jadeite
KR20010084077A (en) * 2000-02-23 2001-09-06 김혁 Method to incrassate korean medical compositions and korean medical jelly incrassated by it
KR101050324B1 (en) * 2003-11-28 2011-07-19 엘지디스플레이 주식회사 Organic electroluminescent device

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100441630B1 (en) * 2001-03-20 2004-07-27 오성천 Functional Yanggaeng Composition Containing Extracts of Soft Core of Antlers
KR20030012714A (en) * 2001-08-04 2003-02-12 양상철 a making method for growth food
KR20030060124A (en) * 2002-01-07 2003-07-16 김준원 Manufacturing method of herb remedy
KR20040024779A (en) * 2002-09-16 2004-03-22 김종수 Food composition

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