KR20010077652A - Compositions for whitening cosmetics - Google Patents

Abstract

PURPOSE: Provided is a whitening cosmetic composition including plant extracts from mixture of Mori Cotex Radicis, blueberry, Sophora japonica L., Portulaca oleracea L., Schizandra chinensis (Turcz.) Baill., soybean, arrowroot and apple. The cosmetic inhibits the activity of tyrosinase and the production of melanine. CONSTITUTION: A whitening cosmetic composition is extracted by depositing dried mixture comprising Mori Cotex Radicis of 15-25 dried wt.%, blueberry of 35-45 dried wt.%, Sophora japonica L. of 5-15 dried wt.%, Portulaca oleracea L. of 15-25 dried wt.% Schizandra chinensis (Turcz.) Baill. of 5-15 dried wt.%, soybean of 5-15 dried wt.%, arrowroot of 5-15 dried wt.% and apple of 5-1 dried wt.% in distilled water, ethanol, methanol, butanol, acetone, ethylacetate, nucleic acid, propanol, butylglycol, or propyleneglycol or a mixture with water at temperature of 5-37 deg.C, for 1-15 days.

Description

Whitening Cosmetic Composition {Compositions for whitening cosmetics}

The present invention relates to a whitening cosmetic composition, and more particularly to a cosmetic composition for showing a whitening effect containing a plant extract obtained from lettuce skin, bilberry, lump, machi, Schisandra chinensis, soybean, brown root, apple mixture.

Skin is a very important tissue that has direct contact with the external environment, protects the human body and has biochemical and physical functions. This tissue is largely divided into three parts: the epidermis, the dermis, and the hypodermis. Melanin is a black pigment produced in the epidermis and is produced in cells called melanocytes. Melanin absorbs the light energy of ultraviolet light (UV) in sunlight, protecting cells deeper from damage caused by ultraviolet light. However, abnormally low production of melanin causes skin lesions such as vitiligo, and on the contrary, excessive synthesis of melanin by UV rays not only damages the skin, but also forms spots and freckles. Sometimes.

Underlying melanogenesis is an enzyme called tyrosinase that is synthesized in melanocytes. Tyrosinase generates dopaquinone via dopa (DOPA) based on an amino acid called tyrosine, and melanin, which is a black pigment, is produced by several stages of oxidative condensation reaction from dopaquinone. Ascorbic acid (JP-A 4-9320), hydroquinone (JP-A 6-192062), kojic acid (JP-A 56-7710), arbutin (JP-A 4-9315) and some extracts have tyrosinase inhibitory activity. Although it is used as a whitening cosmetic, the stability in the prescription system is poorly degraded and colored, or its use is limited due to the occurrence of off-flavor, efficacy at the biological level, unclear effect and safety problems. And the inhibitory effect of tyrosinase has been demonstrated, but the effect is low in experiments similar to the actual biologic level. Therefore, the inhibitory effect of the melanoma cell culture similar to the biological level is required. Hydroquinone is also regulated as a carcinogenic substance and is prohibited from use. Kojic acid and ascorbic acid are very unstable substances. Browning may occur when a small amount of cosmetics are stored at room temperature for several weeks.

Plant natural products are not only safe but also have many beneficial ingredients, making them a good candidate for whitening. Therefore, in order to solve the problems of raw materials having the function of inhibiting skin aging, various effects that can suppress abnormal melanin production from plant extracts having excellent safety, such as herbal medicines, vegetables, fruits and flowers, which are used as herbal medicines Efforts have been made to find extracts that have.

Accordingly, it is an object of the present invention to provide a plant natural product extract that is excellent in whitening effect and has no problems in stability and safety.

Another object of the present invention is to provide a cosmetic composition comprising an extract having such efficacy.

1 is a graph showing the inhibitory effect of tyrosinase activity of the mixed plant extract of the present invention.

Figure 2 is a graph showing the melanin production inhibitory effect of melanoma B16 of the mixed plant extract of the present invention.

Figure 3 is a graph showing the skin whitening improvement effect of the cosmetic composition containing a mixed plant extract of the present invention.

The object of the present invention is achieved by a cosmetic composition containing plant extracts of lettuce, bilberry, curd, machi, schizandra, soybean, brown root, and apple mixture.

The present inventors found that the whitening effect of the mixed plant extract obtained by extracting the eight natural products at a constant mixing ratio was found to show a superior whitening effect than the respective extracts, and solved the stability and safety problems at the same time. In addition, it was found that the combination of plant extracts in a cosmetic composition at a certain concentration or higher results in a clear whitening effect even in the test results applied directly to human skin.

The present invention provides a whitening cosmetic composition containing a mixed plant extract of lettuce, bilberry, lump, machi, Schisandra chinensis, soybean, brown root, apple which can fundamentally prevent abnormal melanin formation.

The extract is added to cosmetics, that is, softening water (skin), nourishing lotion (lotion), nourishing cream, massage cream, essence, pack, and the like.

Hereinafter, the present invention will be described in detail.

First, completely dry the lettuce, bilberry, lump, machi, schisandra, soybean, brown root, and apple, and then, respectively, 15 ~ 25% for baekbaek, 35 ~ 45% for bilberry, 5 ~ 15% for lump, 15-25% , 5 ~ 15% of Schizandra chinensis, 5 ~ 15% of soybean, 5 ~ 15% of brown root, 5 ~ 15% of apple, mixed with distilled water, ethanol, methanol, butanol, acetone, ethyl acetate 10-20 times by volume of one or more solvents selected from the group consisting of hexane, propanol, hydrous butylene glycol, hydrous propylene glycol. Extraction method is a method of extracting by heating at 50-95 ℃ for 4-20 hours or extracting active ingredient at 5-37 ℃ for 1-15 days while cooling condenser is installed to prevent solvent evaporation. Can be. The mixed plant extracts, such as lettuce, bilberry, curd, machi, schizandra, soybean, brown root, and apple, are concentrated under reduced pressure while recovering the solvent that is evaporated using a distillation apparatus equipped with a cooling condenser. It is added to the cosmetic in an amount of 10%, preferably 0.01-5%.

The following Examples and Experimental Examples are for explaining the contents of the present invention, but the contents of the present invention are not limited thereto.

Extract Preparation Example 1.

Eight mixed ingredients of 200 g of dried baekbaek baekpi, 350g of tangerine, 50g of machi, 200g of machi, 50g of Schisandra chinensis, 50g of soybean, 50g of brown root and 50g of apple are placed in 15kg of distilled water and extracted by boiling in an extractor with cooling condenser for 3 hours. After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 34 g (dry weight).

Extract Preparation Example 2

150g of completely dried lettuce, 350g of bilberry, 50g of mackerel, 250g of machi, 50g of Schisandra chinensis, 50g of soybean, 50g of brown root, and 50g of apple, put it in 15kg of ethanol and boil it for 3 hours in an extractor with cooling condenser After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 35 g (dry weight).

Extract Preparation Example 3.

150g of completely dried lettuce, 400g of tangerine, 50g of mackerel, 200g of machi, 50g of Schisandra chinensis, 50g of soybean, 50g of brown root, and 50g of apple, were put into 15kg of methanol and extracted by boiling for 3 hours in an extractor with a cooling condenser. After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 37 g (dry weight).

Extract Preparation Example 4.

150g of completely dried lettuce, 450g of tangerine, 50g of mackerel, 150g of machi, 50g of Schisandra chinensis, 50g of soybean, 50g of brown root, and 50g of apple, put it in 15kg of butanol, and boil it for 3 hours in an extractor with a cooling condenser. After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 29 g (dry weight).

Extract Preparation Example 5.

Eight mixed ingredients of 200g of dried baekbaek baekpi, 350g of tangerine, 50g of machi, 150g of machi, 100g of soybean, 50g of soybean, 50g of brown root, and 50g of apple are placed in 15kg of acetone and extracted by boiling in an extractor with cooling condenser for 3 hours and then 400 mesh After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 32 g (dry weight).

Extract Preparation Example 6.

150g of completely dried lettuce, 350g of brownberry, 50g of mackerel, 200g of machi, 50g of Schisandra chinensis, 100g of soybean, 50g of brown root, 50g of apple, and put it in 15kg of ethyl acetate, boil it for 3 hours in an extractor with a cooling condenser, and extract it. After filtration and cooling to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 33 g (dry weight).

Extract Preparation Example 7.

1 kg of eight mixed ingredients of 150g of dried baekbaek pee, 350g of bilberry, 50g of mackerel, 250g of machi, 50g of soybean, 50g of soybean, 50g of brown root, and 50g of apple were put in 15kg of hexane, boiled for 3 hours in an extractor with cooling condenser, and then 400 mesh After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 30 g (dry weight).

Extract Preparation Example 8.

Eight mixed ingredients of 150g of dried baekbaekpi, 150g of brownberry, 50g of machi, 150g of machi, 100g of Schisandra chinensis, 100g of soybean, 50g of brown root, and 50g of apple were placed in 15kg of propanol and boiled for 3 hours in an extractor with a cooling condenser. After filtration with a filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 32 g (dry weight).

Extract Preparation Example 9.

150g of completely dried lettuce, 350g of bilberry, 50g of machi, 150g of machi, 50g of Schisandra chinensis, 50g of soybean, 100g of brown root, 100g of apple, and 1kg of eight mixed ingredients of 15g of butylene glycol After filtration with a 400 mesh filter cloth, cooled to room temperature and left to age for 7 days at 5-15 ℃ and then filtered with Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 39 g (dry weight).

Extract Preparation Example 10.

Eight mixed ingredients of 150g of dried baekbaek peel, 350g of bilberry, 50g of machi, 150g of machi, 100g of Schisandra chinensis, 50g of soybean, 50g of brown root, and 100g of apple are placed in 15kg of hydrous propylene glycol and extracted by boiling in an extractor with cooling condenser for 3 hours. After filtration with a 400 mesh filter cloth and cooled to room temperature, the mixture was left to mature at 5-15 ° C. for 7 days, and then filtered using Whatman No. 2 filter paper. The mixed plant extract was concentrated under reduced pressure at 60 ° C. in a distillation apparatus equipped with a cooling condenser to obtain 36 g (dry weight).

Experimental Example 1.

The inhibitory effect of tyrosinase activity was measured on the mixed plant extracts of lettuce, bilberry, curd, machi, schizandra, soybean, brown root, and apple obtained in Preparation Example 9.

1) Experiment Method

1.0 mL of L-tyrosine (0.3 mg / mL) was added 1.0 mL of potassium phosphate buffer solution (pH 6.8, 0.1 M) and 0.9 mL of mixed plant extracts of various concentrations at room temperature and maintained at 37 ° C. for 10-20 minutes. After that, 0.1 ml of tyrosinase (1250 units / ml) was added thereto and maintained for 10 minutes. The reaction was terminated under freezing conditions consisting of ice water after taking out within 10 minutes ± 5 seconds. At this time, the control group was added 30% butylene glycol instead of the mixed plant extract of each concentration. Finally, the absorbance was examined at 475 nm. The tyrosinase inhibitory effect of each plant extract at each concentration is determined by the following formula.

% Tyrosinase inhibition =

[1-(enzyme activity of control plant extract at each concentration / enzyme activity of control)] X 100

The results are shown in Table 1 below and graphically shown in FIG. 1.

Table 1. Measurement results of the whitening effect on the mixed crop extract of the present invention

Example Final concentration of the mixed plant extract contained in the reaction solution (µg / ml) Tyrosinase inhibition rate (%) Example 1 20050 8548 Example 2 20050 8852 Example 3 20050 9258 Example 4 20050 8841 Example 5 20050 8952 Example 6 20050 7870 Example 7 20050 7238 Example 8 20050 8252 Example 9 20050 9670 Example 10 20050 9058

Experimental Example 2.

The whitening effect of melanoma B16 was measured on the extracts of lettuce extract, bilberry, blackberry, machi, schizandra, soybean, brown root, and apple mixture obtained in Preparation Example 9.

1) Experimental method.

Melanin production inhibition function was assayed at the cellular level through melanocyte culture. B16 melanoma cells were cultured in 10% bovine melanoma cells for 2 days in the presence of 5% carbon dioxide until 1.0 X 108 cells / T25 flask. Then, mixed plant extracts were added for each concentration and incubated for 2 days in the presence of 5% carbon dioxide. Thereafter, trypsin was added to collect the cells, and the degree of cell blackening was observed. Melanin was quantified by measuring the absorbance at 475 nm, taking the supernatant of melanin-produced and discharged T25 flask, and the number of cells was mixed at the ratio of collected cells: tryphan blue = 1: 9 and observed under a microscope under living microscope. The amount of melanin produced per unit cell was counted to show the inhibitory effect in%.

The results are shown in Table 2 below and graphically shown in FIG. 2.

Table 2. Measurement of Whitening Effect on Mixed Plant Extracts

Example Final concentration of the mixed plant extract contained in the reaction solution (㎍ / ㎖) Melanogenesis inhibition rate (%) Example 1 5010 8039 Example 2 5010 7528 Example 3 5010 7734 Example 4 5010 7319 Example 5 5010 6925 Example 6 5010 5416 Example 7 5010 4622 Example 8 5010 6530 Example 9 5010 8537 Example 10 5010 7930

Prescription Example 1.

Prescription example of a lotion (skin, lotion) in the cosmetic containing the extract of the plant mixture of the present invention is as follows. The extract used herein is that of Example 9.

number Raw material Prescription Example 1 Comparative Example 1 One Mixed Plant Extract 10.0 - 2 glycerin 3.0 3.0 3 Butylene Glycol 2.0 2.0 4 Propylene glycol 2.0 2.0 5 Polyoxyethylene (60) Cured Castor Oil 1.00 1.0 6 ethanol 10.0 10.0 7 Triethanolamine 0.1 0.1 8 antiseptic a very small amount a very small amount 9 Pigment a very small amount a very small amount 10 Spices a very small amount a very small amount 11 Purified water Remaining amount Remaining amount

<Manufacturing method>

Formulation Example 1 No. 2, 3, 4, and 8 were added sequentially in order to dissolve by stirring, and then, No. 5 was heated to 60 ° C. to dissolve and 10 times were added to stirring and added to No. 11. Finally, 1, 6, 7, and 9 were added and sufficiently stirred, and then passed through a mitrofluidizer and aged.

Comparative Example 1: 2, 3, 4, and 8 were added to 11 in order to dissolve by stirring, and 5 was heated to 60 ° C. for dissolution, and 10 was added to 11 to add and stirred. Finally, 6, 7, and 9 times were added and thoroughly stirred, and then passed through a mitrofluidizer and aged.

Prescription Example 2.

A prescription example of nutrient lotion in the cosmetics containing the plant mixture of the present invention is as follows. The extract used herein is that of Example 9.

number Raw material Prescription Example 2 Comparative Example 2 One Mixed plant extracts 10.0 - 2 Cytostolol 1.70 1.70 3 Polyglyceryl 2-oleate 1.50 1.50 4 Ceramide 0.7 0.7 5 Ceteares-4 1.2 1.2 6 cholesterol 1.5 1.5 7 Dicetylphosphate 0.4 0.4 8 Concentrated glycerin 5.0 5.0 9 Sunflower oil 10.0 10.0 10 Carboxy Vinyl Polymer 0.2 0.2 11 Xanthan Gum 0.3 0.3 12 antiseptic a very small amount a very small amount 13 Spices a very small amount a very small amount 14 Purified water Remaining amount Remaining amount

<Manufacturing method>

Formulation Example 2 The raw materials 2,3,4,5 and 6 are homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 1,7,8 and 14 are mixed and homogenized at a constant temperature and passed through a microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then microfluda again. Passed it through again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Comparative Example 2: The raw materials 2,3,4,5 and 6 were homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 2,7,8 and 14 are mixed and homogenized at a constant temperature to pass through a microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then microfluda again. Passed it through again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Prescription Example 3.

Prescription example of nutritional cream in the cosmetic containing the extract of the plant mixture of the present invention is as follows. The extract used herein is that of Example 9.

number Raw material Prescription Example 3 Comparative Example 3 One Mixed plant extracts 10.0 - 2 Cytostolol 4.0 4.0 3 Polyglyceryl 2-oleate 3.0 3.0 4 Ceramide 0.7 0.7 5 Ceteares-4 2.0 2.0 6 cholesterol 3.0 3.0 7 Dicetylphosphate 0.4 0.4 8 Concentrated glycerin 5.0 5.0 9 Sunflower oil 22.0 22.0 10 Carboxy Vinyl Polymer 0.5 0.5 11 Triethanolamine 0.5 0.5 12 antiseptic a very small amount a very small amount 13 Spices a very small amount a very small amount 14 Purified water Remaining amount Remaining amount

<Manufacturing method>

Formulation Example 3 The raw materials 2,3,4,5 and 6 are homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 1,7,8 and 14 are mixed and homogenized at a constant temperature to pass through a microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then microfluda again. Passed it through again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Comparative Example 3: The raw materials 2,3,4,5 and 6 were homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipids and the raw materials 7,8 and 14 are mixed and homogenized at a constant temperature to pass through the microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then again added to the microfluidizer. I passed it again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Prescription Example 4.

A prescription example of a massage cream in cosmetics containing the extract of the plant mixture of the present invention is as follows. The extract used herein is that of Example 9.

number Raw material Prescription Example 4 Comparative Example 4 One Mixed plant extracts 10.0 - 2 Beeswax 10.0 10.0 3 Polysorbate 60 1.5 1.5 4 Sorbitan sesquioleate 0.8 0.8 5 Liquid paraffin 40.0 40.0 6 Squalane 5.0 5.0 7 Caprylic / Capric Triglycerides 4.0 4.0 8 Carboxy Vinyl Polymer 0.2 0.2 9 glycerin 5.0 5.0 10 Butylene glycol 3.0 3.0 11 Propylene glycol 3.0 3.0 12 Triethanolamine 0.2 0.2 13 antiseptic a very small amount a very small amount 14 Pigment a very small amount a very small amount 15 Spices a very small amount a very small amount 16 Purified water Remaining amount Remaining amount

<Manufacturing method>

Prescription example 4: Mixing and stirring 8,9,10,11,13,16 and heating to 80 ~ 85 ° C to put into the manufacturing part, then actuated emulsifier and 2,3,4,5,6,7,12 It heated and heated to 80-85 degreeC, and emulsified. After emulsification, the mixture was cooled to 50 ° C. while stirring using a stirrer, and 14 times were added thereto. After cooling to 25 ℃ it was aged.

Comparative Example 4: 8,9,10,11,13,16 and stirred at 80-85 ° C. while mixing and stirring to put into the manufacturing unit, and then actuated emulsifier and 2,3,4,5,6,7,12 It heated and heated to 80-85 degreeC, and emulsified. After emulsification, the mixture was cooled to 50 ° C. while stirring using a stirrer, and 14 times were added thereto, followed by cooling to 45 ° C., 15 times added thereto, and then cooled to 25 ° C. and aged.

Prescription Example 5.

Prescription examples of nutritional essences in cosmetics containing the extract of the plant mixture of the present invention are as follows. The extract used herein is that of Example 9.

number Raw material Prescription Example 5 Comparative Example 5 One Mixed plant extracts 10.0 - 2 Cytostolol 1.70 1.70 3 Polyglyceryl 2-oleate 1.50 1.50 4 Ceramide 0.7 0.7 5 Ceteares-4 1.2 1.2 6 cholesterol 1.5 1.5 7 Dicetylphosphate 0.4 0.4 8 Concentrated glycerin 5.0 5.0 9 Sunflower oil 15.0 15.0 10 Carboxy Vinyl Polymer 0.2 0.2 11 Xanthan Gum 0.2 0.2 12 antiseptic a very small amount a very small amount 13 Spices a very small amount a very small amount 14 Purified water Remaining amount Remaining amount

<Manufacturing method>

Formulation Example 5 The raw materials 2,3,4,5 and 6 are homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 1,7,8 and 14 are mixed and homogenized at a constant temperature and passed through a microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then microfluda again. Passed it through again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Comparative Example 5: The raw materials 2,3,4,5 and 6 were homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 2,7,8 and 14 are mixed and homogenized at a constant temperature to pass through a microfluidizer, and then the raw material 9 is gradually added at a constant temperature to homogenize and then microfluda again. Passed it through again. 10, 11, 12, 13 was added and dispersed to stabilize and mature.

Experiment to confirm whitening effect on skin

Experimental Example 3. Skin erythema & melanin index measurement experiment

In order to examine the effect of the mixed plant extract on the whitening effect when the nutrition lotions of Formulation Example 2 and Comparative Example 2 were applied to the skin, 20 women were selected as the 20-55 year old female layer. 10 MED (Minimum Ederma Dose) ultraviolet rays were exposed to the left and right arms with a mexameter, and the nutrition lotion of Example 2 was applied to the inside of the left arm, and the nutrition lotion of Comparative Example 2 was applied to the inside of the right arm. After applying twice a day in the morning and evening, erythema index and melanin index were measured using Mexameter after 1 day, 3 days, 5 days, 1 week, 2 weeks, 3 weeks and 4 weeks. The skin whitening effect measured by mexameter is to measure the amount of erythema and melanin production. The smaller the value, the better the whitening effect. The measurement results are shown in Table 3 and FIG. 3.

Table 3.

apply Improvement Number of people Melanin content (%) Erythema amount (%) Example 2 It is effective 12 2 3 is average 5 7 5 There are some changes 3 12 9 No change - - - Comparative Example 2 It is effective - - - is average 4 8 6 There are some changes 5 10 11 No change 11 18 15

As can be seen in the experimental example, the extract of the plant mixture of the present invention has an excellent inhibitory effect on tyrosinase activity and melanin production, the cosmetics prepared by adding the extract of the present invention was excellent in skin whitening effect.

Claims (6)

A whitening cosmetic composition containing extracts of lettuce, bilberry, curd, machi, schizandra, soybean, brown root, and apple mixture. According to claim 1, wherein the mixture is dry weight ratio of 15-25% of baekpipi, 35-45% of bilberry, 5-15% of machi, 15-25% of Portulae, 5-15% of Schisandra chinensis, 5-15% of soybean, 5 Whitening cosmetic composition, characterized in that-15%, and the apple is composed of 5-15%. The whitening cosmetic composition according to claim 1, wherein the extract is contained in an amount of 0.01 to 10% (w / v) as dry weight. The cosmetic composition of claim 1, wherein the cosmetic has a formulation of a lotion (skin lotion), a nutrition lotion, a nutrition cream, a massage cream, or a nutritional essence. Dry mixtures of lettuce, bilberry, curd, machi, Schisandra chinensis, soybean, brown root, and apple are mixed with distilled water, ethanol, methanol, butanol, acetone, ethyl acetate, hexane, propanol, butylene glycol, propylene glycol alone or mixed solvents with water The extraction method of the whitening cosmetic composition characterized by dipping for 1-15 days at 5-37 degreeC. According to claim 1, wherein the mixture is dry weight ratio of 15-25% of baekpipi, 35-45% of bilberry, 5-15% of machi, 15-25% of machi, 5-15% of Schisandra chinensis, 5-15% of soybean, 5 -15%, and the whitening cosmetic composition, characterized in that the apple is mixed by 5-15%