KR20010075748A - cosmetic compositions containing extract of gardenia seeds - Google Patents

Abstract

PURPOSE: A cosmetic composition containing a gardenia extract is provided, which shows an excellent effect on cytotoxicity, allergy induction, coloring performance, color maintaining performance and scavenging effect and has an excellent skin color compensating effect. CONSTITUTION: This cosmetic composition containing 0.01 to 30.0 parts by weight of an extract from Gardenia jasminoides Ellis is characterized in that it compensates the skin color by natural coloring effect of the gardenia extract and has excellent stability.

Description

Cosmetic compositions containing extract of gardenia seeds

The present invention relates to a cosmetic composition having a skin color correction effect. More specifically, the present invention relates to a gardenia extract containing cosmetic composition excellent in skin color correction effect by containing the gardenia extract.

In general, cosmetics are applied to the skin to cleanse, protect, and beautify the skin, and the effect thereof is defined as slight. The products used for this purpose include various types of products such as lotion, latex, cream, essence, foundation, etc. This is commercially available. Particularly, color cosmetics are mostly used as products related to skin beautification, and these cosmetics are colored in order to make the appearance of the skin beautiful at the same time of application, and it is essential to use various powders. These cosmetics have the function of correcting the dull skin color generated by skin aging caused by harmful rays such as ultraviolet rays, various air pollution and excessive stress, and its use is increasing in accordance with the reality that interest in appearance is increasing day by day. In particular, the demand of the elderly is growing. However, various powders used in color cosmetics give a sense of foreign body during makeup and are very likely to remain on the skin even when removing cosmetics, which is cumbersome at the time of cleansing. On the other hand, the basic cosmetics of the lotion and latex formulations have the main purpose of moisturizing, whitening, cleansing, converging, etc., and their effect is inadequate for immediate and remarkable beautification of the appearance of the skin after make-up. There is this.

The present invention is to solve the problems of the prior art as described above, the present inventors have studied with utmost attention, and as a result of the natural effect of hiding the defects of the skin by the coloring action is excellent in the correction effect and excellent in safety, cosmetics of the lotion and emulsion formulation The present invention was completed by using a gardenia extract which is easy to blend in, easy to stabilize, and has no foreign matter during makeup and no residue remains when removing makeup. Accordingly, it is an object of the present invention to provide a composition containing gardenia extract having a skin color correction effect.

Hereinafter, the gardenia extract used in the present invention will be described in more detail.

Gardenia jasminoides (Gardenia jamoides Ellis) or other fruits of the same genus (Gedacea Rubiaceae) in the form of a long egg. It is 1 to 5 cm long and 10 to 15 cm wide, often with six distinct ridges extending vertically. At the upper end there is a calyx or a mark, and at the lower end there is a fruit disease. The outer surface is reddish brown, yellowish brown or blackish brown, and the rind is thin and brittle. Inside surface flat, yellowish brown, glossy. The inside of the fruit is divided into two chambers, with yellowish brown to dark brown flesh, with black brown or yellow red long seed of 5 mm in diameter, and light quality. It has a peculiar smell and the taste is bitter. Since ancient times, it has been used as a contaminant, diuretic, and hemostatic agent in oriental medicine. Inhibitory effect on many fungi, such as yellow fungus, retroepidermal epidermis, and red epidermis. In addition, it was used as a coloring material for food and insect repellent, so it was used for dyeing children's underwear or for dyeing abrasions used for veterinary purposes.

The method of obtaining the gardenia extract used in the present invention is as follows. First, one kilogram of gardenia was thoroughly washed, and then extracted with a common solvent such as 1,3-butylene glycol, propylene glycol, and ethanol. The following experiment was performed with a sample extracted by adding 2 kilograms of purified water and 1 kilogram of solvent. .

Gardenia extract used in the present invention is a dark yellow brown viscous liquid substance with a slight viscous coloring effect when applied to the skin in combination with various cosmetic formulations, ie, cosmetic compositions having a water content of 30 to 95. Not only does it naturally correct, but also has antimicrobial action that can enhance the preservation stability of the product, and there is a weak color change depending on pH, so there is an advantage that the color can be adjusted according to the characteristics of the product. In this experiment, the gardenia extract was less effective than expected in 0.01 parts by weight, and at 30 parts by weight or more, problems occurred when considering the color, smell, and usability when formulated into the product.

Hereinafter, the uniform skin color correction effect, the method of measuring the persistence of the cosmetic composition containing the gardenia extract according to the present invention, a comparative experiment with the foundation and the ease of cleaning through the measurement of the residue during the cleaning will be described in more detail through the experimental example. In addition, it describes the cytotoxicity test and allergenicity test to test the safety of the gardenia extract. However, the present invention is not limited to the following examples.

Coloring effect and persistence

end. Evaluation method

In cosmetics, colorants or pigments correct skin color at the same time as makeup, so that the color change can be visually detected. The color difference meter may measure the degree of skin color correction according to the application of the sample. In addition, in order to correct the skin color, the coloration of the application site should be uniform, so that the application site and the application amount may be uniform and the skin color may be measured for each site to evaluate the degree of uniform coloration. In addition, since cosmetics are easily removed from the skin over time because they are used as a method of physical application on the skin, the persistence of the coloring effect can be evaluated by measuring the color of the surface of the skin after the initial makeup and after elapse of time. . Color measurement was performed by the reflection spectroscopy using a color difference meter. As a control, the foundation of the emulsion formulation was used.

I. Materials and methods

1) Samples and Instruments

*. Experimental Examples 1-4: The emulsion content of the emulsion as shown in Table 1 below (selected the emulsion type as a control similar to the control group).

Content of Gardenia Extract-Containing Cosmetic Composition Experimental Example 1 Experimental Example 2 Experimental Example 3 Experimental Example 4 Paid Cetyloctanoate 4.0 4.0 4.0 4.0 Cyclomethicone 3.0 3.0 3.0 3.0 Liquid paraffin 4.0 4.0 4.0 4.0 Polysorbate 60 5.0 5.0 5.0 5.0 Sorbitan stearate 3.0 3.0 3.0 3.0 Awards Purified water To 100 To 100 To 100 To 100 Butylene glycol 1.0 1.0 1.0 1.0 glycerin 3.0 3.0 3.0 3.0 Propylene glycol 5.0 5.0 5.0 5.0 Glyceres-26 2.0 2.0 2.0 2.0 Gardenia Extract 0.01 1.0 10.0 30.0 Alcoholic ethanol 5.0 5.0 5.0 5.0 incense Quantity Quantity Quantity Quantity Fiji-40 Cured Castor Oil 0.5 0.5 0.5 0.5 Octyldodeceth-16 0.3 0.3 0.3 0.3 additive antiseptic Quantity Quantity Quantity Quantity Pigment Quantity Quantity Quantity Quantity

*. Control: Foundation

*. Instrument: Color difference meter (CR-300, Minolta, Japan)

2) Evaluation method

-. Adapt subject to constant temperature and humidity conditions (25 ℃, relative humidity 45)

-. Clean the lower part with purified water.

-. 10 minutes acclimatization (skin recovery time)

-. Measurement of skin color of experimental part with color difference meter

-. 50 mg of sample was applied to the lower part (5x5 cm ² ) and left for 3 minutes.

-. Measurement of the surface color of the skin at the application site with the color difference meter

-. After 4 hours, measure the surface color of skin

3) results

i) Coloring degree: The color change of the skin surface before and after sample application was measured by the color difference meter, and the result is shown in Table 2.

sample Color Gradient (ΔE) Experimental Example 1 0.12 Experimental Example 2 0.95 Experimental Example 3 1.85 Experimental Example 2.16 Control 4.85

As a result of the experiment, as shown in Table 2, the change of skin color according to the application of the sample containing the gardenia extract showed a significant change when the gardenia extract was 0.01 parts by weight or more. there was. Experimental Examples 1 to 4, although the degree of color change was smaller than the control group, it was more effective in giving a natural correction effect.

ii) Color uniformity: Five of the application sites were arbitrarily selected and measured by a colorimeter, and then the standard deviation was calculated and compared.

sample Deviation L A B Experimental Example 1 0.81 0.54 0.42 Experimental Example 2 0.61 0.34 0.27 Experimental Example 3 0.42 0.29 0.31 Experimental Example 4 0.45 0.32 0.22 Control 1.54 0.61 0.79

As a result, as shown in Table 3, it can be seen that the application of Experimental Examples 1 to 4 containing the gardenia extract is more uniform than that of the control group, indicating that the value of the color difference is small.

iii) Persistence: The color change of the surface of the skin after the initial application and after 4 hours was measured with a colorimeter, and the results are shown in Table 4.

sample Color Gradient (ΔE) Experimental Example 1 0.96 Experimental Example 2 1.09 Experimental Example 3 1.13 Experimental Example 4 1.24 Control 3.16

As a result, as shown in Table 4, it can be seen that the color change of the sites coated with Experimental Examples 1 to 4 containing the gardenia extract is smaller than that of the control group, so that the durability of the sample is excellent. This is expected to be due to the better skin adsorption capacity of the gardenia extract also used as a coloring.

Ease of Cleaning

end. Evaluation method

An important property of cosmetics for temporary skin color correction is ease of cleaning. Gardenia extract has the advantage that it can be easily washed by water because it is water-soluble. In order to measure this quantitatively, after a predetermined time after application of the sample, the sample was removed with a cleaning solution and the amount of residue was measured.

I. Materials and methods

1) Samples and Instruments

*. Experimental Example 5: Latex content is shown in Table 5 (The emulsion type was selected as a control similar to the control).

Content of Gardenia Extract Containing Composition Experimental Example 5 Paid Cetyloctanoate 4.0 Cyclomethicone 3.0 Liquid paraffin 4.0 Polysorbate 60 5.0 Sorbitan stearate 3.0 Awards Purified water To 100 Butylene glycol 1.0 glycerin 3.0 Propylene glycol 5.0 Glyceres-26 2.0 Gardenia Extract 5.0 Alcoholic ethanol 5.0 incense Quantity Fiji-40 Cured Castor Oil 0.5 Octyldodeceth-16 0.3 additive antiseptic Quantity Pigment Quantity

*. Control: Foundation (O / W Formulation)

*. Instrument: Absorption Spectrometer (beckman DU-7000)

2) Evaluation method

-. Adapt subject to constant temperature and humidity conditions (25 ℃, relative humidity 45)

-. Clean the lower part with purified water.

-. 10 minutes acclimatization (skin recovery time)

-. After 8 mg of sample was applied to the lower part (2x2 cm ² ), it was left for 4 hours.

-. Clean the application area by 10 reciprocating movements using a cleaning solution (10ml) and a cotton pad.

-. Completely remove residual sample with wash solution (40 ml).

-. The solution containing the residual sample was measured by an spectrophotometer.

3) results

Table 6 shows the results of calculating the residual amount of each sample using absorbance using a standard curve prepared in advance.

Remaining amount of sample sample Survival rate () Experimental Example 5 1.06 Control 6.24

As a result, as shown in Table 6, Experimental Example 5 containing the gardenia extract can be seen that the residual rate is significantly lower than that of the control group, so that the cleaning is easily performed.

Standard Curve of Experimental Example 5 Standard curve of the control

Cytotoxicity Test

To investigate the cytotoxicity of gardenia jasminoides extracts, MTT [3- (4,5-dimethylthiazol-2-yl] was cultured by culturing V79-4 cells [pulmonary tissue fibroblasts of Chinase Hamster, CCL (continuous cell line)]. ), 2,5-diphenyltetrazolium bromide reduction test] and MTT-formazan product was extracted with isopropyl alcohol to measure the absorbance at 570nm. In order to know the IC ₅₀ (Inhibitory concentration 50) for each substance, the substance was diluted to 10.0, 1.0 ... in the medium and incubated for 24 hours to obtain the IC ₅₀ is shown in Table 7 below.

Cytotoxicity Test Results of Gardenia Extract sample IC ₅₀ (, W / V) SLS 0.0025 Gardenia Extract > 5.0

Gardenia extract was more than 2000 times lower cytotoxicity compared to SLS (sodium lauryl sulfate), it was confirmed that the extract is excellent in safety.

Allergy assessment

In order to check whether allergens are caused by gardenia extract, apply 25µl of sample to mouse ears once a day for 3 days, remove lymph nodes on day 4, separate lymphocytes, and incubate in carbon dioxide incubator for 24-48 hours, and then amplify the radiation. Measured by insertion of isotope [ ³ H] -methyl thymidine. The local lymph node assay (LLNA) results indicate the lymphocyte amplification of the sample group compared to the control group, and allergens when the amplification degree (SI) of the sample increases more than three times and increases with each concentration even at one concentration. Was considered. The results are shown in Table 8 below.

Allergy Evaluation Results of Gardenia Extract sample density() Average cpm Amplification degree (S.I) ethanol 60 2261 ± 121 - Gardenia Extract 50 4548 ± 331 2.0 Gardenia Extract 100 3187 ± 208 1.4

※ cpm (counter per minute): [ ³ H] -methyl thymidine

Amount inserted into the cell

S.I (stimulation index): The mean cpm of the sample is the mean of the control

divided by cpm

As shown in Table 8, it was shown that the amplification degree (S.I) of the gardenia extract is less than 3, and there is little possibility of allergic induction. Thus, the pigmentation effect was excellent and was prepared as follows using the gardenia extract safe for the skin. However, it should be noted that the present invention is not limited to the following preparation examples.

Preparation Example 1.

Flexible Cosmetics Parts by weight Gardenia Extract 3.00 Butylene glycol 5.00 glycerin 2.00 Hyaluronic acid 0.70 Polyethylene oleyl ether 0.10 Polyoxyethylene Cured Castor Oil 0.10 ethanol 8.00 antiseptic 0.10 Spices Quantity Pigment Quantity Purified water To 100

Preparation Example 2.

Nutrition Parts by weight Cetostearyl alcohol 1.00 Self-emulsifying monostearic acid 0.50 Lipophilic monostearic acid 0.50 Beeswax 0.30 Squalane 7.00 Isocetyloctanoate 4.00 Dimethyl Polysiloxane 0.30 Polysorbate 60 0.50 Sorbitan stearate 1.00 Concentrated glycerin 4.00 Propylene glycol 4.00 Carboxy Polymer 0.15 Triethanolamine 0.20 Gardenia Extract 1.00 antiseptic Quantity Spices Quantity Pigment Quantity Purified water To 100

Preparation Example 3.

essence Parts by weight Cetostearyl alcohol 1.00 Self-emulsifying monostearic acid 0.50 Squalane 2.50 Neopentylglycol Dicaprate 1.00 Dimethyl Polysiloxane 0.30 Polysorbate 60 0.50 Polyoxyethylene Cured Castor Oil 1.00 Concentrated glycerin 6.00 Propylene glycol 5.00 Carboxy Polymer 0.20 Triethanolamine 0.30 Gardenia Extract 1.00 antiseptic Quantity Spices Quantity Pigment Quantity Purified water To 100

Preparation Example 4.

Nutrition Cream Parts by weight Cetostearyl alcohol 3.00 Self-emulsifying monostearic acid 1.50 Lipophilic monostearic acid 1.00 Beeswax 0.50 Squalane 7.00 Isocetyloctanoate 4.00 Neopentylglycol Dicaprate 4.00 Dimethyl Polysiloxane 0.30 Polysorbate 60 0.50 Sorbitan stearate 1.00 Concentrated glycerin 5.00 Propylene glycol 4.00 Xanthan Gum 0.05 Triethanolamine 0.10 Gardenia Extract 1.00 antiseptic Quantity Spices Quantity Pigment Quantity Purified water To 100

As described above and can be seen through the experimental example, the gardenia extract-containing cosmetic composition of the present invention exhibits excellent effects in cytotoxicity, allergic potential, coloring ability, color maintenance ability and ease of cleaning. Therefore, the present invention is excellent in skin safety, solubility in blending, so that it is easy to apply, and thus it can be formulated at high concentration, and it is possible to provide a cosmetic composition containing gardenia extract excellent in skin color correction effect, which is a very useful invention in the cosmetic industry. .

Claims (3)

Gardenia extract containing cosmetic composition having a skin color correction effect. 2. The cosmetic composition containing gardenia extract according to claim 1, wherein the skin color correction effect corrects the skin color based on the natural coloring effect of the gardenia extract. The gardenia extract-containing cosmetic composition according to claim 1 or 2, wherein the gardenia extract contains 0.01-30.0 parts by weight of the gardenia extract.