KR20010042481A - Mrp1의 억제 방법 - Google Patents
Mrp1의 억제 방법 Download PDFInfo
- Publication number
- KR20010042481A KR20010042481A KR1020007011101A KR20007011101A KR20010042481A KR 20010042481 A KR20010042481 A KR 20010042481A KR 1020007011101 A KR1020007011101 A KR 1020007011101A KR 20007011101 A KR20007011101 A KR 20007011101A KR 20010042481 A KR20010042481 A KR 20010042481A
- Authority
- KR
- South Korea
- Prior art keywords
- alkyl
- phenyl
- alkoxy
- formula
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8108898P | 1998-04-08 | 1998-04-08 | |
US60/081,088 | 1998-04-08 | ||
PCT/US1999/007615 WO1999051236A1 (en) | 1998-04-08 | 1999-04-07 | Methods for inhibiting mrp1 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20010042481A true KR20010042481A (ko) | 2001-05-25 |
Family
ID=22162031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020007011101A KR20010042481A (ko) | 1998-04-08 | 1999-04-07 | Mrp1의 억제 방법 |
Country Status (17)
Country | Link |
---|---|
US (1) | US6221876B1 (tr) |
EP (1) | EP1067932A4 (tr) |
JP (1) | JP2002510632A (tr) |
KR (1) | KR20010042481A (tr) |
CN (1) | CN1296410A (tr) |
AU (1) | AU3550299A (tr) |
BR (1) | BR9909446A (tr) |
CA (1) | CA2327452A1 (tr) |
EA (1) | EA200001035A1 (tr) |
HU (1) | HUP0102548A2 (tr) |
ID (1) | ID26804A (tr) |
IL (1) | IL138393A0 (tr) |
NO (1) | NO20005041D0 (tr) |
PL (1) | PL343320A1 (tr) |
SK (1) | SK14992000A3 (tr) |
TR (1) | TR200002804T2 (tr) |
WO (1) | WO1999051236A1 (tr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6262098B1 (en) | 1998-08-07 | 2001-07-17 | Chiron Corporation | Estrogen receptor modulators |
ES2233487T3 (es) * | 1999-12-22 | 2005-06-16 | Eli Lilly And Company | Procedimientos y compuestos para la inhibicion de mrp1. |
US6743794B2 (en) | 1999-12-22 | 2004-06-01 | Eli Lilly And Company | Methods and compounds for inhibiting MRP1 |
AU7489101A (en) | 2000-06-14 | 2001-12-24 | Lilly Co Eli | Tricyclic compounds as mrp1-inhibitors |
ATE299883T1 (de) | 2001-04-09 | 2005-08-15 | Lilly Co Eli | Verbindungen und methoden zur hemmung von mrp1 |
CN1281210C (zh) * | 2003-11-29 | 2006-10-25 | 胡汛 | 五味子乙素在制备治疗肿瘤药物中的应用 |
AU2005244872B2 (en) * | 2004-05-14 | 2008-09-11 | Children's Cancer Institute Australia for Medical Research | Small molecule inhibitors for MRP1 and other multidrug transporters |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182290A (en) * | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain oxazoloquinolinones; a new class of GABA brain receptor ligands |
-
1999
- 1999-04-07 KR KR1020007011101A patent/KR20010042481A/ko not_active Application Discontinuation
- 1999-04-07 US US09/646,063 patent/US6221876B1/en not_active Expired - Fee Related
- 1999-04-07 SK SK1499-2000A patent/SK14992000A3/sk unknown
- 1999-04-07 WO PCT/US1999/007615 patent/WO1999051236A1/en not_active Application Discontinuation
- 1999-04-07 HU HU0102548A patent/HUP0102548A2/hu unknown
- 1999-04-07 ID IDW20002006A patent/ID26804A/id unknown
- 1999-04-07 EP EP99917359A patent/EP1067932A4/en not_active Withdrawn
- 1999-04-07 PL PL99343320A patent/PL343320A1/xx not_active Application Discontinuation
- 1999-04-07 CA CA002327452A patent/CA2327452A1/en not_active Abandoned
- 1999-04-07 CN CN99804797A patent/CN1296410A/zh active Pending
- 1999-04-07 TR TR2000/02804T patent/TR200002804T2/tr unknown
- 1999-04-07 EA EA200001035A patent/EA200001035A1/ru unknown
- 1999-04-07 JP JP2000542007A patent/JP2002510632A/ja not_active Withdrawn
- 1999-04-07 BR BR9909446-0A patent/BR9909446A/pt not_active IP Right Cessation
- 1999-04-07 IL IL13839399A patent/IL138393A0/xx unknown
- 1999-04-07 AU AU35502/99A patent/AU3550299A/en not_active Abandoned
-
2000
- 2000-10-06 NO NO20005041A patent/NO20005041D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20005041L (no) | 2000-10-06 |
EP1067932A1 (en) | 2001-01-17 |
JP2002510632A (ja) | 2002-04-09 |
HUP0102548A2 (hu) | 2001-11-28 |
EP1067932A4 (en) | 2001-11-14 |
IL138393A0 (en) | 2001-10-31 |
WO1999051236A1 (en) | 1999-10-14 |
CN1296410A (zh) | 2001-05-23 |
SK14992000A3 (sk) | 2001-06-11 |
AU3550299A (en) | 1999-10-25 |
US6221876B1 (en) | 2001-04-24 |
EA200001035A1 (ru) | 2001-04-23 |
CA2327452A1 (en) | 1999-10-14 |
ID26804A (id) | 2001-02-08 |
TR200002804T2 (tr) | 2001-02-21 |
NO20005041D0 (no) | 2000-10-06 |
BR9909446A (pt) | 2000-12-12 |
PL343320A1 (en) | 2001-08-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |