KR20010042364A - 성숙 FLINT(mFLINT) 폴리펩타이드 또는 TNF수용체인 OPG3의 치료학적 용도 - Google Patents
성숙 FLINT(mFLINT) 폴리펩타이드 또는 TNF수용체인 OPG3의 치료학적 용도 Download PDFInfo
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
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- Animal Behavior & Ethology (AREA)
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- Diabetes (AREA)
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- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7985698P | 1998-03-30 | 1998-03-30 | |
US60/079,856 | 1998-03-30 | ||
US8607498P | 1998-05-20 | 1998-05-20 | |
US60/086,074 | 1998-05-20 | ||
US9964398P | 1998-09-09 | 1998-09-09 | |
US60/099,643 | 1998-09-09 | ||
US11257798P | 1998-12-17 | 1998-12-17 | |
US60/112,577 | 1998-12-17 | ||
US11270398P | 1998-12-18 | 1998-12-18 | |
US11293398P | 1998-12-18 | 1998-12-18 | |
US60/112,703 | 1998-12-18 | ||
US60/112,933 | 1998-12-18 | ||
US11340798P | 1998-12-22 | 1998-12-22 | |
US60/113,407 | 1998-12-22 | ||
PCT/US1999/006797 WO1999050413A2 (en) | 1998-03-30 | 1999-03-30 | THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY |
Publications (1)
Publication Number | Publication Date |
---|---|
KR20010042364A true KR20010042364A (ko) | 2001-05-25 |
Family
ID=27568394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020007010929A KR20010042364A (ko) | 1998-03-30 | 1999-03-30 | 성숙 FLINT(mFLINT) 폴리펩타이드 또는 TNF수용체인 OPG3의 치료학적 용도 |
Country Status (16)
Country | Link |
---|---|
US (1) | US20040167074A1 (xx) |
JP (1) | JP2002512006A (xx) |
KR (1) | KR20010042364A (xx) |
CN (1) | CN1303429A (xx) |
AU (1) | AU3369199A (xx) |
BR (1) | BR9909328A (xx) |
CA (1) | CA2324517A1 (xx) |
CZ (1) | CZ20003433A3 (xx) |
EA (1) | EA200001004A1 (xx) |
HU (1) | HUP0102067A2 (xx) |
ID (1) | ID27820A (xx) |
IL (1) | IL138626A0 (xx) |
NO (1) | NO20004873L (xx) |
PL (1) | PL343847A1 (xx) |
TR (1) | TR200002824T2 (xx) |
WO (1) | WO1999050413A2 (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1007659B1 (en) | 1997-01-14 | 2007-06-27 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6 alpha & 6 beta |
US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
IL134578A0 (en) | 1997-09-18 | 2001-04-30 | Genentech Inc | DcR3 POLYPEPTIDE, A TNFR HOMOLOG |
WO2000037094A2 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
EP1165781B1 (en) * | 1999-03-30 | 2007-08-29 | Eli Lilly And Company | Protease resistant flint analogs |
US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
MXPA02001264A (es) | 1999-08-04 | 2002-07-22 | Amgen Inc | Fhm, nuevo miembro de la familia de supergenes de ligando de factor de necrosis tumoral. |
AU6517800A (en) | 1999-08-04 | 2001-03-05 | Amgen, Inc. | Ntr3, a member of the tnf-receptor supergene family |
WO2001018041A2 (en) * | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint proteins and formulations thereof |
AU1189101A (en) * | 1999-10-20 | 2001-04-30 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
AU1915201A (en) * | 1999-12-07 | 2001-06-18 | Eli Lilly And Company | Improving stability of flint through o-linked glycosylation |
CA2420593A1 (en) * | 2000-08-25 | 2002-03-07 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6.alpha. and 6.beta. |
CA2439193A1 (en) * | 2001-02-23 | 2002-08-29 | Hideki Matsui | Casoase 3 inhibitors |
DE602004022390D1 (de) | 2003-03-26 | 2009-09-17 | Apogenix Gmbh | Verbesserte fc-fusionsproteine |
EP1841442A4 (en) * | 2005-01-07 | 2009-12-09 | Northern Sydney And Central Co | TREATMENT OF AUTOIMMUNE DISEASES AND INFLAMMATORY DISEASES |
PT2101877E (pt) | 2006-12-28 | 2013-07-22 | Deutsches Krebsforsch | Neutralização de atividade de blocos de invasão cd95 de células de glioblastoma in vivo |
JP5665739B2 (ja) * | 2008-07-14 | 2015-02-04 | ドイチェス クレープスフォルシュングスツェントルムDeutsches Krebsforschungszentrum | 炎症性疾患を治療するためのcd95インヒビターの使用 |
CN102671186B (zh) * | 2011-09-19 | 2014-08-06 | 上海市肿瘤研究所 | 促造血的药物组合物及其应用 |
JP6297552B2 (ja) | 2012-07-18 | 2018-03-20 | アポジェニックス アーゲー | Mdsの治療のための、cd95シグナル伝達経路阻害剤 |
EP3076179A1 (en) | 2015-03-30 | 2016-10-05 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Diagnosis and treatment of low grade gliomas |
WO2017101873A1 (zh) | 2015-12-18 | 2017-06-22 | 深圳瑞健生命科学研究院有限公司 | 一种预防或治疗放射性和化学性损伤的方法 |
CN108463235A (zh) | 2015-12-18 | 2018-08-28 | 泰伦基国际有限公司 | 一种用于预防和治疗宫颈糜烂的方法 |
MX2021011608A (es) | 2019-03-29 | 2021-12-10 | Myst Therapeutics Llc | Metodos ex vivo para producir celulas t terapeuticas y composiciones y metodos afines. |
CN115023270A (zh) | 2019-11-27 | 2022-09-06 | 迈斯特治疗公司 | 使用调节剂产生肿瘤反应性t细胞组合物的方法 |
CN115427438A (zh) | 2020-02-27 | 2022-12-02 | 迈斯特治疗公司 | 肿瘤反应性t细胞的离体富集和扩增的方法及其相关组合物 |
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EP1007659B1 (en) * | 1997-01-14 | 2007-06-27 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6 alpha & 6 beta |
US5885800A (en) * | 1997-02-04 | 1999-03-23 | Smithkline Beecham Corporation | DNA encoding tumor necrosis related receptor, TR4 |
AU9013998A (en) * | 1997-07-21 | 1999-02-10 | Zymogenetics Inc. | Tumor necrosis factor receptor ztnfr-5 |
EP1019502A2 (en) * | 1997-08-06 | 2000-07-19 | Regeneron Pharmaceuticals, Inc. | Human orphan receptor ntr-1 |
IL134578A0 (en) * | 1997-09-18 | 2001-04-30 | Genentech Inc | DcR3 POLYPEPTIDE, A TNFR HOMOLOG |
WO1999026977A1 (en) * | 1997-11-24 | 1999-06-03 | Biogen, Inc. | Novel receptors opg-2 |
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- 1999-03-30 JP JP2000541301A patent/JP2002512006A/ja not_active Withdrawn
- 1999-03-30 WO PCT/US1999/006797 patent/WO1999050413A2/en not_active Application Discontinuation
- 1999-03-30 KR KR1020007010929A patent/KR20010042364A/ko not_active Application Discontinuation
- 1999-03-30 HU HU0102067A patent/HUP0102067A2/hu unknown
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HUP0102067A2 (hu) | 2001-10-28 |
TR200002824T2 (tr) | 2000-12-21 |
US20040167074A1 (en) | 2004-08-26 |
BR9909328A (pt) | 2000-12-12 |
CN1303429A (zh) | 2001-07-11 |
EA200001004A1 (ru) | 2001-06-25 |
WO1999050413A2 (en) | 1999-10-07 |
CZ20003433A3 (cs) | 2001-10-17 |
IL138626A0 (en) | 2001-10-31 |
PL343847A1 (en) | 2001-09-10 |
ID27820A (id) | 2001-04-26 |
CA2324517A1 (en) | 1999-10-07 |
NO20004873D0 (no) | 2000-09-28 |
AU3369199A (en) | 1999-10-18 |
NO20004873L (no) | 2000-11-24 |
WO1999050413A3 (en) | 1999-12-02 |
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