KR20010031120A - 신규한 비타민 디 수용체 연관된 폴리펩티드, 이를인코딩하는 핵산 서열 및 이의 용도 - Google Patents

신규한 비타민 디 수용체 연관된 폴리펩티드, 이를인코딩하는 핵산 서열 및 이의 용도 Download PDF

Info

Publication number
KR20010031120A
KR20010031120A KR1020007004011A KR20007004011A KR20010031120A KR 20010031120 A KR20010031120 A KR 20010031120A KR 1020007004011 A KR1020007004011 A KR 1020007004011A KR 20007004011 A KR20007004011 A KR 20007004011A KR 20010031120 A KR20010031120 A KR 20010031120A
Authority
KR
South Korea
Prior art keywords
vdrr
polypeptide
nucleic acid
acid sequence
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020007004011A
Other languages
English (en)
Korean (ko)
Inventor
베르켄스탐안데르스
달베르그마츠
Original Assignee
크리스터 발스트룀, 프레드릭 베르그, 하랄트 알름
파마시아 앤드 업존 에이비
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9703745A external-priority patent/SE9703745D0/xx
Application filed by 크리스터 발스트룀, 프레드릭 베르그, 하랄트 알름, 파마시아 앤드 업존 에이비 filed Critical 크리스터 발스트룀, 프레드릭 베르그, 하랄트 알름
Publication of KR20010031120A publication Critical patent/KR20010031120A/ko
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020007004011A 1997-10-14 1998-08-31 신규한 비타민 디 수용체 연관된 폴리펩티드, 이를인코딩하는 핵산 서열 및 이의 용도 Ceased KR20010031120A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9703745A SE9703745D0 (sv) 1997-10-14 1997-10-14 New receptors
SE9703745-1 1997-10-14
SE9801148A SE9801148D0 (sv) 1997-10-14 1998-03-31 New receptors
SE9801148-9 1998-03-31
PCT/SE1998/001548 WO1999019354A1 (en) 1997-10-14 1998-08-31 Novel vitamin d receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof

Publications (1)

Publication Number Publication Date
KR20010031120A true KR20010031120A (ko) 2001-04-16

Family

ID=26663102

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007004011A Ceased KR20010031120A (ko) 1997-10-14 1998-08-31 신규한 비타민 디 수용체 연관된 폴리펩티드, 이를인코딩하는 핵산 서열 및 이의 용도

Country Status (9)

Country Link
EP (1) EP1023323A1 (enrdf_load_stackoverflow)
JP (1) JP2001519441A (enrdf_load_stackoverflow)
KR (1) KR20010031120A (enrdf_load_stackoverflow)
CN (1) CN1134452C (enrdf_load_stackoverflow)
AU (1) AU732079B2 (enrdf_load_stackoverflow)
CA (1) CA2306453A1 (enrdf_load_stackoverflow)
NZ (1) NZ504025A (enrdf_load_stackoverflow)
SE (1) SE9801148D0 (enrdf_load_stackoverflow)
WO (1) WO1999019354A1 (enrdf_load_stackoverflow)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1044216A4 (en) * 1997-12-12 2001-10-31 Merck & Co Inc DNA MOLECULES ENCODING HUMAN NUCLEAR RECEPTOR PROTEINS, nNR7 AND nNR7-1
US6984773B1 (en) 1998-01-09 2006-01-10 The Salk Institute For Biological Studies Transgenic mice expressing a human SXR receptor polypeptide
US6756491B2 (en) * 1998-01-09 2004-06-29 The Salk Institute For Biological Studies Steroid-activated nuclear receptors and uses therefor
US6911537B2 (en) * 1998-01-09 2005-06-28 The Salk Institute For Biological Studies Xenobiotic compound modulated expression systems and uses therefor
AU2003200641B2 (en) * 1998-01-09 2008-04-03 The Salk Institute For Biological Studies Novel Steroid-activated Nuclear Receptors and Uses therefor
EP1066320A4 (en) * 1998-03-27 2005-03-16 Glaxo Group Ltd ORPHAN NUCLEAR RECEPTOR
US7238491B1 (en) 1998-03-27 2007-07-03 Smithkline Beecham Corporation Pregnane X receptor method
FR2801311B1 (fr) * 1999-11-22 2005-08-26 Centre Nat Rech Scient Polypeptides derives du recepteur nucleaire de la vitamine d, et leurs utilisations notamment dans le cadre du criblage d'analogues de la vitamine d
AU2006200258B2 (en) * 1999-12-09 2009-04-09 The Salk Institute For Biological Studies Novel steroid-activated nuclear receptors and uses therefor
US6514941B1 (en) 1999-12-10 2003-02-04 Campina Melkunie B.V. Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides
US20040053866A1 (en) * 2002-08-21 2004-03-18 The Regents Of The University Of California Tumor suppressor genes and their uses
SE0400489D0 (sv) * 2004-02-27 2004-02-27 Biovitrum Ab Therapeutic proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504438A (ja) * 1988-03-30 1991-10-03 アーチ デベロプメント コーポレイション アンドロジェンレセプターを含むdna結合蛋白質
ATE215601T1 (de) * 1991-09-17 2002-04-15 Salk Inst For Biological Studi Rezeptoren der steroid/thyroid superfamilie von rezeptoren
US5756448A (en) * 1992-02-26 1998-05-26 The General Hospital Corporation Constitute activator of retinoid (CAR) receptor polypeptides
WO1996022390A1 (en) * 1995-01-17 1996-07-25 The Salk Institute For Biological Studies Methods, polypeptides, nucleotide sequence of xor-6, a vitamin d-like receptor from xenopus
AU5426596A (en) * 1995-05-16 1996-11-29 Salk Institute For Biological Studies, The Modulators for new members of the steroid/thyroid superfamily of receptors

Also Published As

Publication number Publication date
WO1999019354A9 (en) 1999-12-02
JP2001519441A (ja) 2001-10-23
EP1023323A1 (en) 2000-08-02
CA2306453A1 (en) 1999-04-22
AU732079B2 (en) 2001-04-12
WO1999019354A1 (en) 1999-04-22
SE9801148D0 (sv) 1998-03-31
NZ504025A (en) 2003-04-29
CN1134452C (zh) 2004-01-14
AU9013198A (en) 1999-05-03
CN1279689A (zh) 2001-01-10

Similar Documents

Publication Publication Date Title
JP2002512781A (ja) Gタンパク質共役型7tm受容体(axor−1)
KR20010031120A (ko) 신규한 비타민 디 수용체 연관된 폴리펩티드, 이를인코딩하는 핵산 서열 및 이의 용도
AU721194B2 (en) Thrombin receptor homolog
JP2002199893A (ja) Gタンパク質共役型受容体hfiao41
EP1157038A1 (en) Cloning of a p2y-like 7tm receptor (axor17)
US20040175789A1 (en) G protein coupled receptors and dna sequences thereof
JP2000083669A (ja) Cxcr4ケモカイン受容体のヒトスプライス変異体cxcr4b
Whittaker et al. Transmembrane domain interactions are necessary for negative cooperativity of the insulin receptor.
US20070207506A1 (en) G-protein coupled receptor and DNA sequences thereof
JPH1118788A (ja) Gタンパク質共役受容体 hofnh30
JPH11151094A (ja) 免疫グロブリン遺伝子スーパーファミリーのメンバーpigrl−1
MXPA00003667A (en) Novel vitamin d receptor related polypeptides, nucleic acid sequence encoding the same and uses thereof
US7118885B2 (en) Nucleic acid encoding vitamin D receptor related polypeptide
JPH1118782A (ja) 新規なヒト・ニューロテンシン・レセプター2型およびそのスプライス変種
JP2002223780A (ja) マウスFrizzled−6遺伝子に類似したヒト7TM受容体
JPH10327879A (ja) 新規ヒト・7−トランスメンブラン受容体をコードしているcDNAクローンHNFDY20
WO2000064942A1 (en) Axor-27, a g-protein coupled receptor
WO2001068816A1 (en) Human histamine h3 gene variant-3
WO2001042486A1 (en) Axor12
JP2002504331A (ja) Gタンパク質共役型受容体AmMaid
JP2002511488A (ja) 新規化合物
US20040106149A1 (en) Novel gpcr hfrbn63
WO2001096562A1 (en) Thyrotropin-releasing hormone receptor-like gpcr (gprfwki)
EP1212347A1 (en) 7tm receptor (axor23)
EP1235859A1 (en) New olfactory receptor polypeptides and dna sequences thereof

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20000414

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
N231 Notification of change of applicant
PN2301 Change of applicant

Patent event date: 20020418

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20030829

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20050228

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20050530

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20050228

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I