KR19980046484A - Shampoo Compositions Containing Oligochitosan - Google Patents

Abstract

The present invention relates to a shampoo composition, and more particularly, it contains oligochitosan, which is partially hydrolyzed by chitosan to form a low molecular weight oligomer having a molecular weight of about 400 to 20,000, thereby enhancing the softness and moisturizing effect of the hair, and itching. It relates to a shampoo composition having a prophylactic effect.

Description

Shampoo Compositions Containing Oligochitosan

The present invention relates to a shampoo composition containing oligochitosan, and more particularly, it contains oligochitosan which has been molecularly hydrolyzed by partially hydrolyzing chitosan to form an oligomer having a molecular weight of about 400 to 20,000, thereby improving the softness and moist feeling of hair. And it relates to a shampoo composition having an anti-itch effect having an antibacterial activity against harmful bacteria such as E. coli.

Conventionally, shampoo compositions which contain various hair conditioning ingredients and impart softness and moisturizing power to the hair are widely known, but in general, these conditioning ingredients have a poor affinity with synthetic anion surfactants used in the shampoo composition, particularly anionic surfactants and the like. In addition, it has a disadvantage of poor oil affinity due to its strong oil properties. In order to overcome these disadvantages, new conditioning agents have been developed, but since the compounding limit is limited in terms of physical properties, sufficient effects cannot be obtained.

In such a situation, the present inventors focused on the fact that while studying the conditioning agent, since chitin and chitosan, which are rich in natural resources after cellulose on the planet, have good adsorptive power, they can be used as conditioning agents in hair cosmetics such as shampoos. To study.

However, chitosan is a kind of amino polysaccharide derived from nature. It is a polymer form of D-glucosamine obtained by deacetalization of chitin contained in crab, epidermis of shrimp, insects and bones of mollusks. Since it is a polymer form of about 5000 bounds, it cannot be expected to have a physiological activity by itself, and thus does not show satisfactory effects in conditioning effects such as adsorption force.

Accordingly, the present inventors have been searching for a method to solve the problem of lowering the conditioning effect due to the high molecular weight of chitosan, and by combining the oligochitosan, which is partially hydrolyzed by oligomerization, to the conventional shampoo composition, It effectively prevents roughness and stiffness and removes waste, so it provides excellent hair softness and moist feeling, and maintains hair care easily.Anti-dandruff effect is provided by the antibacterial activity of oligochitosan. Knowing that the present invention was completed.

Accordingly, an object of the present invention is to prevent the roughness and stiffness of the hair and to remove the waste to effectively enhance the moist and soft feel of the hair, to provide a shampoo composition having an anti-dandruff effect.

In order to achieve the above object, the shampoo composition according to the present invention is characterized in that it contains oligochitosan in an amount of 0.01 to 5% by weight based on the total weight of the composition.

Other objects and applications of the present invention will become apparent from the following detailed description.

Hereinafter, the present invention will be described in more detail.

Oligochitosan is an oligosaccharide in which two or three D-glucosamines are bonded, and can be obtained by partial hydrolysis of chitosan. Since oligochitosan has the advantages of having physiological activities such as antibacterial and anticancer effects and immune enhancing effects, it may be usefully used in cosmetics.

Method for producing oligochitosan as an active ingredient of the shampoo composition of the present invention is as follows.

A chitosan solution is prepared in a ratio of 99 g of 1% aqueous acetic acid solution and 1 g of chitosan, and a 10% aqueous sodium hydroxide solution is slowly added until the pH reaches 4.5. 5% chitosanase solution, an enzyme, was added at a rate of 3% by weight of the chitosan solution while reacting for 4 hours while maintaining a pH of 4.5 to 5.0 and a temperature of 50 ° C. Heating removes enzymatic activity. The solution is concentrated at 85 ° C. to no more than 1/5 of the filtrate. To this concentrate is washed 5 times ethanol slowly, followed by complete ethanol removal and drying as much as possible. The dried product was ground and then sieved through a 500 mesh sieve to prepare a low molecular weight final oligochitosan in the form of an oligomer having a molecular weight of about 400 to 20,000.

Since oligochitosan used in the present invention is a low molecule in oligomer form compared to chitosan or chitin liquid, which are widely used in cosmetics, it can provide excellent conditioning effects such as softness and moist texture by increasing the adsorption amount per unit area of hair or scalp.

The oligochitosan used in the shampoo composition of the present invention is used in an amount of 0.01 to 5% by weight, and preferably in an amount of 0.01 to 2% by weight, based on the total weight of the composition. If the content of oligochitosan is less than 0.01% by weight, a satisfactory effect is not obtained. If the content of the oligochitosan is less than 5% by weight, the effect is excellent, but the manufacturing cost is high and the composition is poor in stability and physical properties.

Hereinafter, the essential component and optional component which comprise the shampoo composition of this invention are demonstrated.

[Surfactants]

The synthetic surfactant used in the present invention may be any selected from anionic, amphoteric, nonionic and cationic surfactants, and the surfactant is 10 to 70% by weight, preferably 10 to 30% by weight based on the total weight of the composition. Used in% amounts.

Synthetic anionic surfactants that can be used in the present invention are alkyl and alkyl ether sulfates, represented by the following formula (1).

In said formula, R is a C10-C22 alkyl group, n is an integer of 0-4, M is chosen from water-soluble cations, such as ammonium, sodium, and triethanolamine. Preferably, alkyl sulfates and alkyl ether sulfates having 12 to 16 carbon atoms of R are preferable. Alcohols can be derived from or synthesized from fats such as palm oil or tallow. In the present invention, lauryl alcohol and straight chain alcohol derived from palm oil are preferable. This alcohol is reacted with about 1 to 4 moles of ethylene oxide, in particular 3 moles, for example to sulfate and neutralize the resulting mixture in the molecule having an average of 3 moles of ethylene oxide per mole of alcohol. Specific examples of these include sodium lauryl sulfate, lauryl ammonium sulfate, lauryl triethanolamine, sodium polyoxyethylene lauryl sulfate, and polyoxyethylene lauryl sulfate.

Synthetic amphoteric surfactants are alkylbetaines and alkylamidopropylbetaines, represented by formulas (2) and (3).

In said formula, R <_1> is a C8-18 alkyl group and R <_2> CO is a C8-18 alkoxy group. Specific examples include cocodimethylcarboxymethylbetaine, lauryldimethylcarboxymethylbetaine, lauryldimethyl α-carboxyethylbetaine, cetyldimethylcarboxymethyl, cocoamido propylbetaine and the like.

Synthetic nonionic surfactants are represented by Formulas 4 and 5 as alkanolamides and alkylamine oxides.

In the above formula, R ₁ is an alkyl group having 8 to 18 carbon atoms, R ₂ and R ₃ are alkyl groups having 1 to ₃ carbon atoms, R ₄ CO is an alkoxy group having 8 to 16 carbon atoms, and n is 0 or 1. Specific examples include lauryl diethylamine oxide, palm oil alkyldimethylamine oxide, lauric acid diethanolamide, palm oil fatty acid diethanolamide, palm oil fatty acid monoethanol amide, and the like.

The above-mentioned surfactants can be selected and used alone or in combination in the shampoo composition of the present invention.

[Optional ingredients]

The optional ingredients used in the compositions of the present invention are well known to those skilled in the art as customary optional ingredients for maintaining basic physical properties and quality. As specific examples, pearlescent aids, preservatives, thickeners, viscosity regulators, pH regulators, perfumes, dyes, hair conditioning agents are used.

Pearlescent aids such as, for example, ethylene glycol, monostearate, ethylene glycol distearate; Preservatives such as methyl paraoxybenzoate, methylchloroisothiazolinone and methylisothiazolinone; Viscosity modifiers such as sodium chloride, ammonium chloride, propylene glycol; PH adjusting agents such as citric acid, phosphoric acid, sodium hydroxide, potassium hydroxide; Hair conditioning agents such as polyquaternium-10, polyquaternium-7, methylpolysiloxane, dimethylconcopolyol, hydrolyzed animal protein; Dyestuffs such as water soluble tars are used, and perfumes may be used.

Hereinafter, the shampoo composition of the present invention will be described in more detail with reference to examples of the present invention, but the present invention is not limited to these examples.

[Examples 1-6 and Comparative Examples 1-2]

Raw material name Comparative example Example One 2 3 4 5 6 One 2 1.Sodium polyoxyethylene lauryl ether sulfate 30% 30.0 30.0 30.0 30.0 30.0 30.0 30.0 30.0 2. Sodium Lauryl Sulfate 28% 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 3. Lauryl diethanolamide 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4. Propylene Glycol 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5 5.Methylparahydroxybenzoate 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 6. Pigment Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity 7. Incense Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity 8. Citric acid Quantity Quantity Quantity Quantity Quantity Quantity Quantity Quantity 9. Polyquaternium-7 · 1.0 · · 1.0 1.0 · 1.0 10. Chitin Liquid · · 1.0 · 1.0 · · · 11. Chitosan (dissolved in propylene glycol) · · · 1.0 · 1.0 · · 12. Oligochitosan · · · · · · 1.0 1.0 13. Purified water to100 to100 to100 to100 to100 to100 to100 to100

[Manufacturing method]

Raw materials 1-3 are added to water, and after stirring, raw materials 9-12 are added, and 4-8 which is a conventional shampoo composition is thrown in, and then it is prepared by stirring.

[Test Example 1] Test of softness and moist texture of hair

The effects on the soft and moist texture of the hair were evaluated in five stages by 10 panelists once a day for 15 days. The results are shown in Table 1.

[Evaluation standard]

* Soft texture of hair

Power supply felt soft enough. ......... 5 points

8 to 9 people felt the soft enough. ....... 4 points

6 to 7 people felt the soft enough. 3 points

4 to 5 people felt the soft enough. ....... 2 points

0 to 3 people felt the soft enough texture. ....... 1 point

* Moist texture of hair

The power felt moist enough. ......... 5 points

8 to 9 people felt the texture sufficiently moist. ....... 4 points

6 to 7 people felt the moist enough texture. 3 points

4 to 5 people felt the texture enough moist. ....... 2 points

0 to 3 people felt the texture sufficiently moist. ....... 1 point

Soft texture of hair Moist texture of hair Comparative Example 1 One One Comparative Example 2 One One Comparative Example 3 3 2 Comparative Example 4 2 3 Comparative Example 5 3 3 Comparative Example 6 3 3 Example 1 4 5 Example 2 5 5

As shown in Table 1, the shampoo composition of the present invention enhances the soft touch and moist feel of the hair than the shampoos of Comparative Examples 1-6. In addition, shampoo compositions containing oligochitosan (Example 1) or shampoo compositions used with other conditioning ingredients (Example 2) were found to be superior in softness and moist feel compared to shampoo compositions containing chitosan and chitosan liquid.

[Test Example 2] MIC effect experiment on the microorganisms (antibacterial action)

The test bacteria were streaked on the agar plates containing the shampoos of the comparative examples and examples according to the concentrations, and the test bacteria were incubated under aerobic conditions for 2 days. The concentration (MIC) was measured to confirm the antimicrobial activity against the test bacteria.

Test bacteria

Cause of dandruff:

Propionbacteriuum acnes ATCC 11817

Eschericia Coil ATCC 10536

Streptococcous mutants ATCC 11827

Staphylococcus epidermidis ATCC 12228

Saccharomyces cerevisiae ATCC 24702

Pityrosprum ovale ATCC 12087

2. Medium used

Blood agar medium (blood agar base + final concentration 5%, blood), BHI agar

Minimum Inhibitory Concentration (MIC) Sample Test Bacteria Comparative example Example One 2 3 4 5 6 One 2 Propionibacterium Acnes 0.5 0.5 0.150 0.120 0.100 0.050 0.020 0.005 Shersia Colai 0.5 0.5 0.230 0.280 0.080 0.090 0.050 0.010 Streptococcus mutans 0.5 0.5 0.090 0.100 0.070 0.060 0.005 0.003 Staphylococco epidermidis 0.5 0.5 0.380 0.270 0.150 0.120 0.110 0.008 Saccharomyces cervix 0.5 0.5 0.180 0.150 0.100 0.110 0.070 0.007 Fitirosporum Ovalle 0.5 0.5 0.280 0.240 0.013 0.014 0.120 0.008

As can be seen in Table 2, it can be seen that the shampoo composition of the present invention has superior antimicrobial activity against harmful bacteria such as Escherichia coli than the shampoos of Comparative Examples 1 to 6. In addition, Example 2 using the oligochitosan in combination with the polyquaternium-7, a cationic polymer, it can be seen that the antibacterial activity is further increased by increasing the adsorption amount of the hair running the anion charge.

[Test Example 3] scalp anti-itch effect test

56 men who felt relatively itching were selected and the shampoos of each example and the comparative example were divided into seven groups of eight people for two months and the results are shown in Table 3.

[Evaluation standard]

Very itchy ..... 1 point

Slightly itchy ..... 2 points

Normal ..... 3 points

It is OK ..... 4 points

Not itchy ..... 5 points

Scalp itching effect Comparative example Example One 2 3 4 5 6 One 2 Scalp itching effect 1.2 1.3 1.6 1.7 2.3 2.7 3.7 4.5

As shown in Table 3, it can be seen that the effect of removing the scalp itch in the Example containing the oligochitosan of the present invention. Furthermore, it can be seen that when it contains polyquaternium-7, which is a cationic polymer (Example 2), the amount of hair adsorption of the active ingredient is increased, so that the effect of preventing itching is excellent.

As described above, the shampoo composition containing oligochitosan contains a conventional shampoo composition and chitosan or chitin in preventing hair roughness and stiffness to prevent hair softness and moist feeling, antibacterial activity against harmful microorganisms, and anti-itch effect. It can be seen that it shows an excellent effect compared to one shampoo composition. In addition, when the oligochitosan is used together with a conditioning agent such as polyquaternium-7, the above-described effects can be obtained even more because the amount of the active ingredient is increased to the anion hair.

Claims (1)

A shampoo composition, wherein the shampoo composition comprises oligochitosan, which has been molecularly reduced to an oligomer having a molecular weight of 400 to 20,000, in an amount of 0.01 to 5% by weight based on the total weight of the composition.