KR102958459B1 - 약제학적 조성물 - Google Patents

약제학적 조성물

Info

Publication number
KR102958459B1
KR102958459B1 KR1020217023943A KR20217023943A KR102958459B1 KR 102958459 B1 KR102958459 B1 KR 102958459B1 KR 1020217023943 A KR1020217023943 A KR 1020217023943A KR 20217023943 A KR20217023943 A KR 20217023943A KR 102958459 B1 KR102958459 B1 KR 102958459B1
Authority
KR
South Korea
Prior art keywords
copolymer
pharmaceutical composition
kda
composition according
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020217023943A
Other languages
English (en)
Korean (ko)
Other versions
KR20210113251A (ko
Inventor
크리스또프 로베르즈
아돌포 로뻬즈 노히에갸
쟝 마뉘엘 크로
쥴리엣뜨 세행두
뮤리엘 오스터
팡 리우
샤를로트 몰리니에
실베스트르 그리조
타사 브리닉
페이페이 응
엘리스 구에가인
마리-에메랑티엔 카뇽
Original Assignee
메딘셀 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메딘셀 에스.에이. filed Critical 메딘셀 에스.에이.
Priority to KR1020267012731A priority Critical patent/KR20260061472A/ko
Publication of KR20210113251A publication Critical patent/KR20210113251A/ko
Application granted granted Critical
Publication of KR102958459B1 publication Critical patent/KR102958459B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020217023943A 2019-01-08 2020-01-08 약제학적 조성물 Active KR102958459B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020267012731A KR20260061472A (ko) 2019-01-08 2020-01-08 약제학적 조성물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1900258.3A GB201900258D0 (en) 2019-01-08 2019-01-08 Pharmaceutical composition
GB1900258.3 2019-01-08
PCT/EP2020/050333 WO2020144239A1 (en) 2019-01-08 2020-01-08 Pharmaceutical composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020267012731A Division KR20260061472A (ko) 2019-01-08 2020-01-08 약제학적 조성물

Publications (2)

Publication Number Publication Date
KR20210113251A KR20210113251A (ko) 2021-09-15
KR102958459B1 true KR102958459B1 (ko) 2026-04-29

Family

ID=65528088

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020217023943A Active KR102958459B1 (ko) 2019-01-08 2020-01-08 약제학적 조성물
KR1020267012731A Pending KR20260061472A (ko) 2019-01-08 2020-01-08 약제학적 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020267012731A Pending KR20260061472A (ko) 2019-01-08 2020-01-08 약제학적 조성물

Country Status (25)

Country Link
US (3) US12485139B2 (cg-RX-API-DMAC7.html)
EP (2) EP3908321B1 (cg-RX-API-DMAC7.html)
JP (2) JP7680355B2 (cg-RX-API-DMAC7.html)
KR (2) KR102958459B1 (cg-RX-API-DMAC7.html)
CN (1) CN113543775B (cg-RX-API-DMAC7.html)
AU (1) AU2020205438B9 (cg-RX-API-DMAC7.html)
BR (1) BR112021013456A2 (cg-RX-API-DMAC7.html)
CA (1) CA3125372A1 (cg-RX-API-DMAC7.html)
DK (1) DK3908321T3 (cg-RX-API-DMAC7.html)
EA (1) EA202191603A1 (cg-RX-API-DMAC7.html)
ES (1) ES2968432T3 (cg-RX-API-DMAC7.html)
FI (1) FI3908321T3 (cg-RX-API-DMAC7.html)
GB (1) GB201900258D0 (cg-RX-API-DMAC7.html)
HR (1) HRP20231667T1 (cg-RX-API-DMAC7.html)
HU (1) HUE064916T2 (cg-RX-API-DMAC7.html)
LT (1) LT3908321T (cg-RX-API-DMAC7.html)
MX (1) MX2021008248A (cg-RX-API-DMAC7.html)
PH (1) PH12021551642A1 (cg-RX-API-DMAC7.html)
PL (1) PL3908321T3 (cg-RX-API-DMAC7.html)
PT (1) PT3908321T (cg-RX-API-DMAC7.html)
RS (1) RS65067B1 (cg-RX-API-DMAC7.html)
SI (1) SI3908321T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202400011T1 (cg-RX-API-DMAC7.html)
WO (1) WO2020144239A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202104704B (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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IL301609A (en) * 2020-10-01 2023-05-01 Standard Millox Pharmaceuticals Oy Hydrogel material
MX2024001681A (es) 2021-08-05 2024-03-04 Medincell S A Composicion farmaceutica.
AU2024381207A1 (en) 2023-11-17 2026-05-14 Institut National de la Santé et de la Recherche Médicale Antineoplastic combinations
WO2026013080A1 (en) 2024-07-08 2026-01-15 InnoCore Technologies Holding B.V. Pharmaceutical composition based on biodegradable polymers comprising polyoxazoline

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CN106832844B (zh) 2017-02-10 2018-11-20 四川大学 一种四臂peg-pcl、氧化石墨烯复合材料及其制备方法
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Also Published As

Publication number Publication date
EP3908321A1 (en) 2021-11-17
JP7680355B2 (ja) 2025-05-20
CA3125372A1 (en) 2020-07-16
ZA202104704B (en) 2024-11-27
FI3908321T3 (fi) 2024-01-11
EP4289429A2 (en) 2023-12-13
PH12021551642A1 (en) 2022-05-23
PT3908321T (pt) 2024-01-15
SI3908321T1 (sl) 2024-03-29
AU2020205438B8 (en) 2025-03-27
US20260115226A1 (en) 2026-04-30
DK3908321T3 (da) 2024-01-15
AU2020205438A1 (en) 2021-07-29
JP2022517939A (ja) 2022-03-11
EP3908321B1 (en) 2023-11-15
CN113543775B (zh) 2023-11-24
JP2025066716A (ja) 2025-04-23
US20220118003A1 (en) 2022-04-21
US20240293444A1 (en) 2024-09-05
AU2020205438B2 (en) 2025-02-06
WO2020144239A1 (en) 2020-07-16
GB201900258D0 (en) 2019-02-27
CN113543775A (zh) 2021-10-22
US12427165B2 (en) 2025-09-30
SMT202400011T1 (it) 2024-03-13
EP4289429A3 (en) 2024-03-20
BR112021013456A2 (pt) 2021-09-14
RS65067B1 (sr) 2024-02-29
ES2968432T3 (es) 2024-05-09
PL3908321T3 (pl) 2024-03-25
US12485139B2 (en) 2025-12-02
KR20210113251A (ko) 2021-09-15
MX2021008248A (es) 2021-10-13
KR20260061472A (ko) 2026-05-06
HRP20231667T1 (hr) 2024-03-15
HUE064916T2 (hu) 2024-04-28
LT3908321T (lt) 2024-01-25
EA202191603A1 (ru) 2021-10-20
AU2020205438B9 (en) 2025-03-27

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