KR102949204B1 - 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법 - Google Patents

알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법

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KR102949204B1
KR102949204B1 KR1020217014887A KR20217014887A KR102949204B1 KR 102949204 B1 KR102949204 B1 KR 102949204B1 KR 1020217014887 A KR1020217014887 A KR 1020217014887A KR 20217014887 A KR20217014887 A KR 20217014887A KR 102949204 B1 KR102949204 B1 KR 102949204B1
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sequence
sgrna
rna
nucleic acid
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KR20210102883A (ko
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조나단 더글라스 핀
혼-렌 황
모이트리 로이
케디 라이
레이첼 새틀러
크리스토스 카이랏사우스
청 왕
Original Assignee
인텔리아 테라퓨틱스, 인크.
리제너론 파마슈티칼스 인코포레이티드
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Priority to KR1020267010209A priority Critical patent/KR20260048369A/ko
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    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
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    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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KR1020217014887A 2018-10-18 2019-10-18 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법 Active KR102949204B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020267010209A KR20260048369A (ko) 2018-10-18 2019-10-18 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862747402P 2018-10-18 2018-10-18
US62/747,402 2018-10-18
US201962840346P 2019-04-29 2019-04-29
US62/840,346 2019-04-29
PCT/US2019/057086 WO2020082042A2 (en) 2018-10-18 2019-10-18 Compositions and methods for transgene expression from an albumin locus

Related Child Applications (1)

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KR1020267010209A Division KR20260048369A (ko) 2018-10-18 2019-10-18 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법

Publications (2)

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KR20210102883A KR20210102883A (ko) 2021-08-20
KR102949204B1 true KR102949204B1 (ko) 2026-04-07

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KR1020217014887A Active KR102949204B1 (ko) 2018-10-18 2019-10-18 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법
KR1020267010209A Pending KR20260048369A (ko) 2018-10-18 2019-10-18 알부민 좌위로부터 트랜스진을 발현하기 위한 조성물 및 방법

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US (2) US20200270617A1 (https=)
EP (1) EP3867381A2 (https=)
JP (2) JP7472121B2 (https=)
KR (2) KR102949204B1 (https=)
CN (1) CN114207130A (https=)
AU (1) AU2019361203B2 (https=)
BR (1) BR112021007343A2 (https=)
CA (1) CA3116918A1 (https=)
CO (1) CO2021006363A2 (https=)
IL (1) IL282236A (https=)
MX (1) MX2021004278A (https=)
MY (1) MY208564A (https=)
PH (1) PH12021550844A1 (https=)
SA (1) SA521421766B1 (https=)
SG (1) SG11202103733SA (https=)
TW (2) TWI860300B (https=)
WO (1) WO2020082042A2 (https=)

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