KR102903277B1 - 상피 장벽 기능 장애 치료용 단백질 - Google Patents

상피 장벽 기능 장애 치료용 단백질

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Publication number
KR102903277B1
KR102903277B1 KR1020237032575A KR20237032575A KR102903277B1 KR 102903277 B1 KR102903277 B1 KR 102903277B1 KR 1020237032575 A KR1020237032575 A KR 1020237032575A KR 20237032575 A KR20237032575 A KR 20237032575A KR 102903277 B1 KR102903277 B1 KR 102903277B1
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KR
South Korea
Prior art keywords
seq
protein
amino acid
acid sequence
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020237032575A
Other languages
English (en)
Korean (ko)
Other versions
KR20230144097A (ko
Inventor
앤드류 원희 한
앤드류 윗먼 굿이어
타룬미트 구즈랄
토드 자캐리 데산티스
카림 다바흐
토시히코 타케우치
예 진
미치 이주미 윌콕슨
스테파니 바나스
Original Assignee
제네바이브, 인크.
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Publication date
Application filed by 제네바이브, 인크. filed Critical 제네바이브, 인크.
Publication of KR20230144097A publication Critical patent/KR20230144097A/ko
Application granted granted Critical
Publication of KR102903277B1 publication Critical patent/KR102903277B1/ko
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
KR1020237032575A 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질 Active KR102903277B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201762482963P 2017-04-07 2017-04-07
US62/482,963 2017-04-07
US201762607706P 2017-12-19 2017-12-19
US62/607,706 2017-12-19
US201762611334P 2017-12-28 2017-12-28
US62/611,334 2017-12-28
KR1020197032830A KR20200003821A (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질
PCT/US2018/026447 WO2018187682A1 (en) 2017-04-07 2018-04-06 Proteins for the treatment of epithelial barrier function disorders

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020197032830A Division KR20200003821A (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Publications (2)

Publication Number Publication Date
KR20230144097A KR20230144097A (ko) 2023-10-13
KR102903277B1 true KR102903277B1 (ko) 2025-12-23

Family

ID=63710147

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020237032575A Active KR102903277B1 (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질
KR1020197032830A Ceased KR20200003821A (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020197032830A Ceased KR20200003821A (ko) 2017-04-07 2018-04-06 상피 장벽 기능 장애 치료용 단백질

Country Status (12)

Country Link
US (3) US10251933B2 (enExample)
EP (1) EP3606542A4 (enExample)
JP (2) JP7789303B2 (enExample)
KR (2) KR102903277B1 (enExample)
CN (1) CN110769844B (enExample)
AU (2) AU2018248324B2 (enExample)
CA (1) CA3059354A1 (enExample)
IL (1) IL269853A (enExample)
MX (2) MX393998B (enExample)
SG (1) SG11201909334TA (enExample)
TW (1) TWI797116B (enExample)
WO (1) WO2018187682A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10251933B2 (en) 2017-04-07 2019-04-09 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
EP3773644A4 (en) * 2018-04-06 2021-06-02 Second Genome, Inc. PROTEINS FOR TREATMENT OF EPITHELIAL BARRIER FUNCTION DISORDERS
JP2022512639A (ja) * 2018-10-09 2022-02-07 セカンド ゲノム インコーポレイテッド 上皮バリア機能障害の治療に有効なタンパク質を送達するためのラクトコッカス・ラクティス発現系
US20210079086A1 (en) * 2019-08-21 2021-03-18 Astrazeneca Collaboration Ventures, Llc Use of Brazikumab to Treat Crohn's Disease
EP4087859A4 (en) * 2020-01-10 2024-02-14 National Taipei University of Technology PEPTIDE INTERACTING WITH THE TOLL-LIKE RECEPTOR 2 AND COMPOSITION THEREOF
CN113773364B (zh) * 2021-08-25 2023-04-28 无锡市儿童医院 小分子肽及其制备方法和应用
JP2025542567A (ja) * 2022-11-04 2025-12-26 ミンク セラピューティクス，インコーポレイティッド Ｂ細胞成熟抗原（ｂｃｍａ）キメラ抗原受容体インバリアントナチュラルキラーｔ細胞及びその用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013050792A1 (en) * 2011-10-07 2013-04-11 Gt Biologics Ltd Bacterium for use as a probiotic for nutritional and medical applications

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US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5571702A (en) 1991-03-29 1996-11-05 Genentech, Inc. Amplification method for detection of human PF4A receptors
AR053579A1 (es) * 2005-04-15 2007-05-09 Genentech Inc Tratamiento de la enfermedad inflamatoria intestinal (eii)
ES2568938T3 (es) 2009-04-28 2016-05-05 Vanderbilt University Composiciones y procedimientos de tratamiento de trastornos que implican apoptosis de células epiteliales
JP2014093482A (ja) 2012-11-06 2014-05-19 Toshiba Corp 固体撮像装置の製造方法および固体撮像装置
GB201306536D0 (en) * 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
WO2015014973A2 (en) * 2013-07-31 2015-02-05 Institut National De La Recherche Agronomique Use of specific glycoside phosphorylases for the implementation of phosphorolysis or reverse phosphorolysis reactions
WO2016203221A1 (en) * 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
US10251933B2 (en) 2017-04-07 2019-04-09 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11666627B2 (en) * 2017-04-07 2023-06-06 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders
US11174293B2 (en) 2017-06-02 2021-11-16 Second Genome, Inc. Proteins for the treatment of epithelial barrier function disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013050792A1 (en) * 2011-10-07 2013-04-11 Gt Biologics Ltd Bacterium for use as a probiotic for nutritional and medical applications

Also Published As

Publication number Publication date
JP2024037834A (ja) 2024-03-19
JP2020516615A (ja) 2020-06-11
EP3606542A4 (en) 2021-01-20
SG11201909334TA (en) 2019-11-28
AU2023202844A1 (en) 2023-07-06
MX393998B (es) 2025-03-24
US20240066095A1 (en) 2024-02-29
US20180289770A1 (en) 2018-10-11
TWI797116B (zh) 2023-04-01
CA3059354A1 (en) 2018-10-11
KR20230144097A (ko) 2023-10-13
WO2018187682A1 (en) 2018-10-11
AU2018248324B2 (en) 2023-02-09
US10251933B2 (en) 2019-04-09
CN110769844B (zh) 2025-01-21
EP3606542A1 (en) 2020-02-12
AU2018248324A1 (en) 2019-10-31
US20200148728A1 (en) 2020-05-14
US11207376B2 (en) 2021-12-28
CN110769844A (zh) 2020-02-07
MX2022008842A (es) 2022-08-02
IL269853A (en) 2019-11-28
TW201841649A (zh) 2018-12-01
KR20200003821A (ko) 2020-01-10
MX2019012051A (es) 2020-02-12
JP7789303B2 (ja) 2025-12-22

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