KR102809909B1 - P53 암-특이적 돌연변이에 대한 항원 특이성을 갖는 t 세포를 단리하는 방법 - Google Patents

P53 암-특이적 돌연변이에 대한 항원 특이성을 갖는 t 세포를 단리하는 방법 Download PDF

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KR102809909B1
KR102809909B1 KR1020207012343A KR20207012343A KR102809909B1 KR 102809909 B1 KR102809909 B1 KR 102809909B1 KR 1020207012343 A KR1020207012343 A KR 1020207012343A KR 20207012343 A KR20207012343 A KR 20207012343A KR 102809909 B1 KR102809909 B1 KR 102809909B1
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드루 씨 데니거
스티븐 에이 로젠버그
파리사 말렉자데
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더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
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KR1020207012343A 2017-09-29 2018-09-17 P53 암-특이적 돌연변이에 대한 항원 특이성을 갖는 t 세포를 단리하는 방법 Active KR102809909B1 (ko)

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US201762565464P 2017-09-29 2017-09-29
US62/565,464 2017-09-29
PCT/US2018/051280 WO2019067242A1 (en) 2017-09-29 2018-09-17 METHODS FOR ISOLATING T CELLS HAVING ANTIGENIC SPECIFICITY FOR SPECIFIC MUTATION OF CANCER P53

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KR20200065026A KR20200065026A (ko) 2020-06-08
KR102809909B1 true KR102809909B1 (ko) 2025-05-22

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US (1) US20200316121A1 (enExample)
EP (2) EP4495133A3 (enExample)
JP (1) JP7391015B2 (enExample)
KR (1) KR102809909B1 (enExample)
CN (1) CN111344394A (enExample)
AU (1) AU2018342245B2 (enExample)
CA (1) CA3080274A1 (enExample)
IL (1) IL273516B2 (enExample)
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WO (1) WO2019067242A1 (enExample)

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DE102016123847B3 (de) 2016-12-08 2018-04-05 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
NZ754365A (en) 2016-12-08 2022-02-25 Immatics Biotechnologies Gmbh Novel t cell receptors and immune therapy using the same
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
US11807662B2 (en) 2017-05-16 2023-11-07 The Johns Hopkins University MANAbodies and methods of using
CA3144070A1 (en) 2019-06-27 2020-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors recognizing r175h or y220c mutation in p53
CN112390875B (zh) * 2019-08-16 2023-01-24 香雪生命科学技术（广东）有限公司 一种识别afp的高亲和力t细胞受体
CN115210255A (zh) * 2019-12-17 2022-10-18 约翰斯霍普金斯大学 靶向肿瘤抗原的mana抗体及其使用方法
CN115244173A (zh) 2019-12-20 2022-10-25 英研生物(英国)有限公司 用于分离肿瘤浸润淋巴细胞的装置及方法及其用途
CA3191186A1 (en) * 2020-09-04 2022-03-10 Sanghyun Kim T cell receptors recognizing r273c or y220c mutations in p53
CN112301088B (zh) * 2020-10-21 2022-12-13 杭州纽安津生物科技有限公司 一种筛选新生抗原或新生抗原编码序列的方法
JP2024507929A (ja) 2021-02-25 2024-02-21 アラウノス セラピューティクス インコーポレイテッド 多シストロン性発現カセットを含む組換えベクター及びそれらの使用方法
JP2024509472A (ja) * 2021-03-08 2024-03-01 大鵬薬品工業株式会社 Ｆｇｆｒ２及び癌ドライバー遺伝子に遺伝子変化が同時発生する患者におけるがんの治療
CN117794944A (zh) * 2021-03-31 2024-03-29 约翰斯霍普金斯大学 靶向肿瘤抗原的方法和材料
WO2022236050A1 (en) * 2021-05-07 2022-11-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors recognizing c135y, r175h, or m237i mutation in p53
JP2024525727A (ja) 2021-07-14 2024-07-12 ２セブンティ バイオ インコーポレイテッド 抗体由来の結合ドメインに融合した操作されたｔ細胞受容体
AU2022377062A1 (en) * 2021-10-29 2024-05-30 David Hou T cell receptor recognizing r175h mutation in p53 and its application
KR20250008809A (ko) 2022-04-08 2025-01-15 리제너론 파마슈티칼스 인코포레이티드 다분할 수용체 및 신호전달 복합체
WO2024131372A1 (zh) * 2022-12-23 2024-06-27 上海市第一人民医院 靶向巨细胞病毒pp65的TCR和表达其的T细胞及应用
AU2024277363A1 (en) * 2023-05-25 2025-12-11 Elicio Therapeutics, Inc. Compositions containing p53 peptide amphiphiles and methods of use thereof
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WO2025060149A1 (zh) * 2023-09-22 2025-03-27 上海市第一人民医院 一种分离的tcr及其用途

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EP4495133A3 (en) 2025-04-09
AU2018342245B2 (en) 2024-06-13
US20200316121A1 (en) 2020-10-08
JP2020534839A (ja) 2020-12-03
AU2018342245A1 (en) 2020-04-16
SG11202002635RA (en) 2020-04-29
EP4495133A2 (en) 2025-01-22
CN111344394A (zh) 2020-06-26
IL273516B2 (en) 2025-06-01
EP3688142A1 (en) 2020-08-05
EP3688142B1 (en) 2025-04-09
IL273516A (en) 2020-05-31
IL273516B1 (en) 2025-02-01
WO2019067242A1 (en) 2019-04-04
JP7391015B2 (ja) 2023-12-04
KR20200065026A (ko) 2020-06-08
CA3080274A1 (en) 2019-04-04

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