KR102808155B1 - 면역 반응 조절용 탄수화물-개질 입자 및 미립자 제제 - Google Patents

면역 반응 조절용 탄수화물-개질 입자 및 미립자 제제 Download PDF

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KR102808155B1
KR102808155B1 KR1020177037203A KR20177037203A KR102808155B1 KR 102808155 B1 KR102808155 B1 KR 102808155B1 KR 1020177037203 A KR1020177037203 A KR 1020177037203A KR 20177037203 A KR20177037203 A KR 20177037203A KR 102808155 B1 KR102808155 B1 KR 102808155B1
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particle
carbohydrate
antigen
cells
tolerance
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KR20180012796A (ko
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파울 제이. 브라이스
카렌 비. 치엔
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노쓰웨스턴유니버시티
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
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    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
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    • A61K47/6931—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
    • A61K47/6935—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being obtained otherwise than by reactions involving carbon to carbon unsaturated bonds, e.g. polyesters, polyamides or polyglycerol
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    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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KR1020177037203A 2015-05-27 2016-05-27 면역 반응 조절용 탄수화물-개질 입자 및 미립자 제제 Active KR102808155B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562167054P 2015-05-27 2015-05-27
US62/167,054 2015-05-27
PCT/US2016/034765 WO2016191723A1 (en) 2015-05-27 2016-05-27 Carbohydrate-modified particles and particulate formulations for modulating an immune response

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KR20180012796A KR20180012796A (ko) 2018-02-06
KR102808155B1 true KR102808155B1 (ko) 2025-05-16

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US (3) US20160346382A1 (enExample)
EP (1) EP3302446A4 (enExample)
JP (3) JP6882269B2 (enExample)
KR (1) KR102808155B1 (enExample)
CN (2) CN108024969A (enExample)
AU (1) AU2016267671B2 (enExample)
BR (1) BR112017025422A2 (enExample)
IL (2) IL293655B2 (enExample)
MX (1) MX2017015127A (enExample)
RU (1) RU2752620C2 (enExample)
WO (1) WO2016191723A1 (enExample)
ZA (1) ZA201708600B (enExample)

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US9597385B2 (en) 2012-04-23 2017-03-21 Allertein Therapeutics, Llc Nanoparticles for treatment of allergy
EP3760223A1 (en) 2013-04-03 2021-01-06 N-Fold Llc Nanoparticle composition for desensitizing a subject to peanut allergens
JP7653696B2 (ja) 2016-12-09 2025-03-31 ノースウエスタン ユニバーシティ 骨形成促進温度応答性巨大分子
WO2018209259A1 (en) * 2017-05-11 2018-11-15 Northwestern University Intravascular retrievable cell delivery system
WO2019023060A2 (en) 2017-07-28 2019-01-31 Kimberly-Clark Worldwide, Inc. NANOPOROUS SUPERABSORBENT PARTICLES
BR112021004081A2 (pt) * 2018-09-04 2021-05-25 Ecole Polytechnique Federale De Lausanne (Epfl) nanopartículas virucidas, composição farmacêutica, composição virucida, método de desinfecção e/ou esterilização, dispositivo e uso das nanopartículas virucidas
GB201819759D0 (en) * 2018-12-04 2019-01-23 Phytoquest Ltd Bioactive phytochemicals in zizphus and guarana
CN115212198A (zh) * 2021-04-15 2022-10-21 北京大学第三医院（北京大学第三临床医学院） 一种组合物在制备预防、缓解、治疗泪腺功能低下的药物方面的应用
CN113143939A (zh) * 2021-06-07 2021-07-23 长春中医药大学 贝母素甲在制备预防和/或治疗溃疡性结肠炎药物中的应用
CN114042441B (zh) * 2021-12-09 2024-05-03 云南师范大学 在血液灌流树脂微球表面修饰并固载肝素的方法及其制备的吸附剂

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US20150118318A1 (en) 2012-04-12 2015-04-30 Yale University Methods of Treating Inflammatory and Autoimmune Diseases and Disorders

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RU2017145397A3 (enExample) 2019-12-02
IL293655B1 (en) 2024-12-01
JP6882269B2 (ja) 2021-06-02
KR20180012796A (ko) 2018-02-06
AU2016267671A1 (en) 2018-01-18
CN108024969A (zh) 2018-05-11
BR112017025422A2 (pt) 2018-08-07
IL255944A (en) 2018-01-31
JP7369734B2 (ja) 2023-10-26
MX2017015127A (es) 2018-06-22
JP2018515627A (ja) 2018-06-14
IL255944B (en) 2022-07-01
US20210205443A1 (en) 2021-07-08
IL293655B2 (en) 2025-04-01
JP2021130665A (ja) 2021-09-09
US20160346382A1 (en) 2016-12-01
JP2023130428A (ja) 2023-09-20
CN117815381A (zh) 2024-04-05
IL293655A (en) 2022-08-01
WO2016191723A1 (en) 2016-12-01
EP3302446A1 (en) 2018-04-11
ZA201708600B (en) 2022-05-25
EP3302446A4 (en) 2019-01-09
RU2017145397A (ru) 2019-06-28
AU2016267671B2 (en) 2021-09-23
RU2752620C2 (ru) 2021-07-29
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