KR102697493B1 - Tp53의 반접합성 손실을 지닌 암을 치료하는 방법 - Google Patents

Tp53의 반접합성 손실을 지닌 암을 치료하는 방법 Download PDF

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KR102697493B1
KR102697493B1 KR1020177028574A KR20177028574A KR102697493B1 KR 102697493 B1 KR102697493 B1 KR 102697493B1 KR 1020177028574 A KR1020177028574 A KR 1020177028574A KR 20177028574 A KR20177028574 A KR 20177028574A KR 102697493 B1 KR102697493 B1 KR 102697493B1
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polr2a
cancer
delete delete
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슝빈 루
윤화 류
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더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템
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KR1020177028574A 2015-03-04 2016-03-03 Tp53의 반접합성 손실을 지닌 암을 치료하는 방법 Active KR102697493B1 (ko)

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US201562128480P 2015-03-04 2015-03-04
US62/128,480 2015-03-04
PCT/US2016/020687 WO2016141185A1 (en) 2015-03-04 2016-03-03 Methods of treating cancer harboring hemizygous loss of tp53

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RU2721953C2 (ru) 2015-03-04 2020-05-25 Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем Способы лечения рака, имеющего гемизиготную потерю тр53
CN109661400A (zh) 2016-06-17 2019-04-19 美真达治疗公司 用于耗尽cd117+细胞的组合物和方法
CN110461876B (zh) 2017-01-20 2024-05-17 海德堡医药研究有限责任公司 用于耗尽cd137+细胞的组合物和方法
WO2020092602A1 (en) * 2018-10-30 2020-05-07 Ohio State Innovation Foundation Ph-activated nanoparticles
US12275781B2 (en) 2019-02-01 2025-04-15 Board Of Regents, The University Of Texas System Monoclonal antibodies against MHC-bound human dickkopf-1 peptides and uses thereof
CN111569076B (zh) * 2020-06-28 2022-05-17 中国农业科学院特产研究所 Polr2a抑制剂在制备药物中的应用
CN114875107B (zh) * 2021-05-19 2025-05-27 中南大学 Polr2a作为治疗肿瘤疗效的生物标志物
CN113702648B (zh) * 2021-09-13 2024-06-04 中南大学湘雅三医院 Polr2a在作为预测抗肿瘤药物的抗肿瘤疗效的生物标志物上的应用

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