KR102666931B1 - 면역세포 조성물을 생산하는 방법 - Google Patents

면역세포 조성물을 생산하는 방법 Download PDF

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KR102666931B1
KR102666931B1 KR1020220039335A KR20220039335A KR102666931B1 KR 102666931 B1 KR102666931 B1 KR 102666931B1 KR 1020220039335 A KR1020220039335 A KR 1020220039335A KR 20220039335 A KR20220039335 A KR 20220039335A KR 102666931 B1 KR102666931 B1 KR 102666931B1
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immune cell
cells
cell population
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KR20220136919A (ko
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이희진
이규진
박혜선
공경엽
임채열
김영애
최지일
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주식회사 네오젠티씨
재단법인 아산사회복지재단
울산대학교 산학협력단
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    • C12N5/0602—Vertebrate cells
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • C12M23/00—Constructional details, e.g. recesses, hinges
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/30—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cancer cells, e.g. reversion of tumour cells

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Clinical Laboratory Science (AREA)
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KR1020220039335A 2021-03-30 2022-03-30 면역세포 조성물을 생산하는 방법 Active KR102666931B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020240053740A KR20240078405A (ko) 2021-03-30 2024-04-23 면역세포 조성물을 생산하는 방법

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KR20210040926 2021-03-30
KR1020210040926 2021-03-30

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KR20220136919A KR20220136919A (ko) 2022-10-11
KR102666931B1 true KR102666931B1 (ko) 2024-05-20

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KR1020240053740A Pending KR20240078405A (ko) 2021-03-30 2024-04-23 면역세포 조성물을 생산하는 방법

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US (1) US20240181053A1 (enExample)
EP (1) EP4317423B1 (enExample)
JP (1) JP2024512978A (enExample)
KR (2) KR102666931B1 (enExample)
WO (1) WO2022211491A1 (enExample)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120244133A1 (en) * 2011-03-22 2012-09-27 The United States of America, as represented by the Secretary, Department of Health and Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
JOP20190224A1 (ar) * 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
WO2019136459A1 (en) * 2018-01-08 2019-07-11 Iovance Biotherapeutics, Inc. Processes for generating til products enriched for tumor antigen-specific t-cells
CA3094957A1 (en) * 2018-03-29 2019-10-03 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2019210131A1 (en) * 2018-04-27 2019-10-31 Iovance Biotherapeutics, Inc. Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2019217753A1 (en) * 2018-05-10 2019-11-14 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
WO2020096927A1 (en) * 2018-11-05 2020-05-14 Iovance Biotherapeutics, Inc. Expansion of tils utilizing akt pathway inhibitors
KR20200092155A (ko) * 2019-01-24 2020-08-03 울산대학교 산학협력단 종양침윤림프구를 유효성분으로 포함하는 삼중음성 유방암 예방 또는 치료용 조성물
WO2020232029A1 (en) * 2019-05-13 2020-11-19 Iovance Biotherapeutics, Inc. Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
CN110938594A (zh) * 2019-09-12 2020-03-31 夏建川 一种功能增强型til细胞的培养方法

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US20240181053A1 (en) 2024-06-06
EP4317423B1 (en) 2026-05-06
JP2024512978A (ja) 2024-03-21
KR20240078405A (ko) 2024-06-03
EP4317423A4 (en) 2025-04-09
KR20220136919A (ko) 2022-10-11
EP4317423A1 (en) 2024-02-07
WO2022211491A1 (ko) 2022-10-06

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