KR102631008B1 - Cosmetic composition and method for producing the same - Google Patents

Abstract

The present invention relates to a cosmetic composition, and more specifically, to a cosmetic composition and the same that are excellent in skin regeneration and soothing, hydrating and itching alleviating effects, and help blood circulation to give vitality and elasticity to the skin. It is about manufacturing method.

Description

Cosmetic composition and method for producing the same {Cosmetic composition and method for producing the same}

The present invention relates to a cosmetic composition, and more specifically, to a cosmetic composition and the same that are excellent in skin regeneration and soothing, hydrating and itching alleviating effects, and help blood circulation to give vitality and elasticity to the skin. It is about manufacturing method.

The main functions of human skin are to block ultraviolet rays, block external pollutants such as microorganisms and chemicals, and regulate body temperature. Starting from the surface, the skin is composed of the epidermis, dermis, and subcutaneous fat layer, and is also composed of pores and sweat glands.

The epidermal layer is composed of the stratum corneum, granular layer, stratum spinosum, and basal layer. Among these, the stratum corneum constitutes the skin barrier and is responsible for blocking external substances and maintaining moisture in the dermal layer. The epidermal layer is about 10 to 20㎛ thick and has protein-filled cells buried in non-polar lamellar lipids between cells. The main components of the lipid layer, which is the core of the skin barrier, are cholesterol (30%), free fatty acids (15%), and ceramide (50%). The main components of the lipid layer are derived from lamellar bodies of the granular layer.

Pores contain organs called sebaceous glands that secrete sebum. From here, it is secreted into the hair follicles, and if there is a problem when sebum is discharged out of the body through sweat, the pores become enlarged. When pores become enlarged, the skin becomes dry and loses elasticity.

The correlation between skin temperature and sebum and pores has been revealed in several papers, and there are reports that generally, when skin temperature rises, it becomes drier and pores become larger. In addition, it is known that blackheads and acne are correlated with skin temperature.

Therefore, using cosmetics with cooling and soothing effects that lower skin temperature can help moisturize the skin, shrink pores, blackheads, and acne, creating healthy skin with fewer problems.

Meanwhile, keratinocytes are characteristic cells in which basal cells that continuously proliferate in the lowest layer of the epidermis gradually undergo changes in form and function and rise to the skin surface. After a certain period of time, old keratinocytes disappear. They are shed from the skin and new keratinocytes take over their function. This repetitive series of changes is called “epidermal cell differentiation” or “keratinization.”

In addition, during the keratinization process, keratinocytes produce natural moisturizing factor (NMF) and intercellular lipids (ceramide, cholesterol, fatty acids) to form the stratum corneum, making the stratum corneum firm and flexible, thereby strengthening the skin barrier. It functions as a barrier.

This stratum corneum can easily lose its function due to lifestyle factors such as excessive washing or bathing, environmental factors such as dry air pollutants, and endogenous diseases such as atopic skin or senile skin. In fact, in modern times, Recently, due to various factors that have increased, the number of people complaining of dry skin symptoms and various disorders resulting from it has been increasing.

In addition, even if the skin is healthy, the skin condition may worsen due to lack of moisture due to harsh external environments, such as wind, cold weather, sunlight, washing the face, and shaving. Therefore, it is very important to maintain the appropriate moisture content of the skin's keratin cell layer.

Accordingly, the present inventors have reduced side effects such as skin irritation and damage, have a regenerative effect on skin troubles and skin damage, have a cooling and soothing effect on hot skin, and further help with skin moisturization, elasticity, and whitening. We have developed a cosmetic composition with the optimal composition and mixing ratio that allows this.

Republic of Korea Patent Publication No. 10-2015-0145745

The present invention is intended to solve the above problems, and is a cosmetic composition that has excellent skin regeneration and soothing, moisturizing, and itching-relieving effects, and helps blood circulation to give vitality and elasticity to the skin, and its preparation. We would like to provide a method.

The above and other objects and advantages of the present invention will become apparent from the following description of preferred embodiments.

The above objective can be achieved by a cosmetic composition, characterized in that it contains Guaiazulene, Hyaluronic acid, Cyanocobalamin and camellia oil as active ingredients. there is.

The active ingredient is characterized in that it is contained in 0.1 to 8% by weight based on the total weight of the cosmetic composition.

The mixing ratio of Guaiazulene, Hyaluronic acid, Cyanocobalamin, and camellia oil is a weight ratio of 1: 1 to 1.3: 0.8 to 1: 0.5 to 0.7. It is characterized by

The cosmetic composition is characterized in that it further contains 0.01 to 3.5% by weight of a second active ingredient containing extracts of natural ingredients, based on the total weight.

The second active ingredient is any one selected from the group consisting of Achyranthes apiaceae extract, peony root extract, L. chinensis extract, niacinamide, pantothenic acid, allantoin, orange extract, biotin, panthenol, Centella asiatica extract, aloe extract, and combinations thereof. It is characterized by

The cosmetic composition is characterized by further comprising at least one moisturizing agent selected from sodium hyaluronate, glycerin, propylene glycol, 1,3-butylene glycol, dipropylene glycol, erythritol, and sorbitol.

The cosmetic composition is characterized in that it further comprises one or more thickeners selected from polyacrylate, xanthan gum, methylcellulose, hydroxyethylcellulose, carbomer, carrageenan, carboxymethylcellulose and hydroxymethylcellulose.

The cosmetic composition is characterized by further comprising at least one pH adjuster selected from citric acid, sodium hydroxide, triethanolamine, sodium citrate, phosphoric acid, sodium phosphate, lactic acid, and tromethamine.

The cosmetic composition includes solution, suspension, emulsion, paste, gel, essence, cream, lotion, ampoule, softening lotion, nourishing lotion, powder, soap, cleansing, oil, foundation, wax, pack, powder, pact, lip gloss. , It is characterized in that it is manufactured in the form of lipstick, shadow, shampoo, rinse, or spray.

According to the present invention, it is excellent in regenerating and soothing the skin, supplying moisture, improving skin exfoliation, and alleviating itching, and can exert the effect of helping blood circulation, giving vitality and whitening to the skin, and increasing elasticity.

In addition, the cosmetic composition of the present invention minimizes skin irritation and can be used not only on the facial skin but also on the entire body, so dryness and itchiness of the skin can be significantly improved through a full body massage after a shower.

The cosmetic composition can be easily manufactured into various formulations and product forms, such as lotion, essence, lotion, cream, and mist.

However, the effects of the present invention are not limited to the effects mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the description below.

Hereinafter, the present invention will be described in detail with reference to embodiments of the present invention and drawings. These examples are merely presented as examples to explain the present invention in more detail, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples. .

Additionally, unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as commonly understood by a person skilled in the art to which the present invention pertains, and in case of conflict, this specification including definitions The description will take precedence.

In order to clearly explain the proposed invention in the drawings, parts unrelated to the description have been omitted, and similar reference numerals have been assigned to similar parts throughout the specification. And, when it is said that a part "includes" a certain component, this means that it does not exclude other components, but may further include other components, unless specifically stated to the contrary. Additionally, “unit” as used in the specification refers to a unit or block that performs a specific function.

Identification codes (first, second, etc.) for each step are used for convenience of explanation. The identification codes do not describe the order of each step, and each step does not clearly state a specific order in context. It may be carried out differently from the order specified above. That is, each step may be performed in the same order as specified, may be performed substantially simultaneously, or may be performed in the opposite order.

In the present invention, 'extract' means that an extract is separated and obtained from a natural ingredient raw material using extraction and separation methods known in the art, and the extract defined in the present invention is an extract as defined above using an appropriate solvent. The ingredient raw materials prepared by the method may be extracted as is or by pulverizing them. At this time, the appropriate solvent that can be used to obtain the extract may be any solvent acceptable in the art, and water or an organic solvent may be used. For example, alcohols with 1 to 4 carbon atoms, including purified water, methanol, ethanol, propanol, isopropanol, butanol, acetone, and ether. , various solvents such as benzene, chloroform, ethyl acetate, methylene chloride, hexane, and cyclohexane can be used individually or in combination. It is not limited.

As an extraction method, for example, any one of the following methods can be selected and used: hot water extraction, cold needle extraction, reflux cooling extraction, solvent extraction, steam distillation, ultrasonic extraction, elution, compression, and infrared extraction.

In addition, the desired extract may be further subjected to a conventional fractionation process or may be purified using a conventional purification method. There is no limitation to the method for producing the extract of the present invention, and any known method can be used.

For example, the extract contained in the composition of the present invention may be used as is by centrifuging, filtering, concentrating, and then freeze-drying the primary extract extracted by the solvent extraction method described above and storing it in a refrigerator. The primary extract may be stored in a refrigerator under reduced pressure. It can be produced in powder form by additional processes such as distillation and freeze-drying or spray drying.

In addition, the primary extract was further purified using various chromatographies such as silica gel column chromatography, thin layer chromatography, high performance liquid chromatography, etc. A fraction can also be obtained.

Therefore, in the present invention, “extract” is a concept that includes all extracts, fractions, and purifications obtained at each stage of extraction, fractionation, or purification, as well as their dilutions, concentrates, or dried products.

Hereinafter, implementation examples and examples of the present application will be described in detail. However, the disclosure may not be limited to these embodiments and examples.

One aspect of the present application provides a cosmetic composition comprising guaiazulene, hyaluronic acid, cyanocobalamin, and camellia oil as active ingredients. .

The guaiazulene is an organic compound made by synthesizing pure guaiazulene obtained from chamomile with sodium sulfur trioxide. Guaiazulene is an ingredient obtained from the oil of chamomile, a herb whose name means apple that grows from the ground. Chamomile is native to Europe, North Africa, and North Asia. It has a sweet and refreshing apple scent and is enjoyed as a tea or used for bathing and beauty treatments.

The guaiazulene is used as a natural pigment that exhibits blue color and is suitable for use in skin soothing, skin blood circulation and recovery, skin regeneration, and wound treatment.

The hyaluronic acid provides moisture to dry skin and exerts effects such as improving skin moisturization, improving wrinkles, and improving elasticity.

When the hyaluronic acid is mixed with the guaiazulene at a specific weight ratio and used together, the synergy of the functionality of each ingredient can be maximized.

The cyanocobalamin (Cyanocobalamin) is vitamin B12, has cobalt located in the molecule, and has excellent effects in regulating skin condition, skin regeneration, and improving skin tone.

The camellia oil is an oil extracted from the fruit of the camellia tree and is mainly produced in East Asia, such as Korea, China, and Japan. Camellia oil contains oleic acid, a component similar to skin, so it is friendly to the skin and has effects such as high moisturizing, supplying nutrients, improving elasticity, and revitalizing the skin through blood circulation.

Based on the total weight of the cosmetic composition, the active ingredient may be included in an amount of 0.01 to 10% by weight, specifically, 0.1 to 8% by weight.

When the active ingredient is included in the above-described content range, the highest synergy in formulation stability, skin cooling, soothing effect, and skin elasticity enhancement effect can be achieved.

The mixing ratio of Guaiazulene, Hyaluronic acid, Cyanocobalamin and camellia oil is a weight ratio of 1: 1 to 1.3: 0.8 to 1: 0.5 to 0.7, an example. Therefore, it is preferable to mix at a weight ratio of 1:1.2:0.85:0.6.

The cosmetic composition may further include 0.01 to 3.5% by weight of a second active ingredient containing extracts of natural ingredients, based on the total weight.

The second active ingredient is, for example, selected from the group consisting of Achyranthesia extract, peony root extract, Gwangju tree extract, niacinamide, pantothenic acid, allantoin, orange extract, biotin, panthenol, Centella asiatica extract, aloe extract, and combinations thereof. It could be any one.

As an example, the second active ingredient may be a mixture of Agi swimming extract, Agi swimming extract, peony root extract, Chrysanthemum tree extract, niacinamide, and pantothenic acid.

The second active ingredient, which is composed of the above-mentioned ingredients, can further increase the effect of improving functionality such as skin soothing, skin cooling, skin regeneration, moisturizing power, skin elasticity, and skin vitality by the above-mentioned active ingredients. , the efficacy of each component of the second active ingredient can be added to the cosmetic composition.

In addition to the above-mentioned ingredients, the cosmetic composition may further include additional ingredients and other additives that can be blended into conventional cosmetic compositions.

The additional ingredients include, for example, surfactants, humectants, thickeners, pH adjusters, preservatives, water, solubilizers, suspending agents, antioxidants, sequestrants, disinfectants, anti-inflammatory agents, antimicrobial agents, solubilizers or flavoring agents. , dyes, pigments, etc. may be further included.

The surfactants include, for example, anionic surfactants such as ammonium lauryl sulfosuccinate and ammonium lauryl sulfate, and nonionic surfactants such as polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, and polysorbate 80. etc. is possible. In addition, cationic surfactants such as tertiary aliphatic amine salts and alkyltrimethylammonium chloride, and amphoteric surfactants such as betaine and amide betaine types may be used.

The moisturizer may be sodium hyaluronate, glycerin, propylene glycol, 1,3-butylene glycol, dipropylene glycol, erythritol, sorbitol, etc., and the thickener may be polyacrylate, xanthan gum, methylcellulose, hydroxyl It can be compounds such as ethylcellulose, carbomer, carrageenan, carboxymethylcellulose, and hydroxymethylcellulose. Additionally, the pH adjuster may specifically include citric acid, sodium hydroxide, triethanolamine, sodium citrate, phosphoric acid, sodium phosphate, lactic acid, tromethamine, etc.

The preservative may be benzoic acid, paraoxybenzoic acid ester, a mixture of methylchloroisothiazolinone, phenoxyethanol, DMDMhydantoin, etc., and the antioxidant may specifically include dibutylhydroxytoluene, ascorbic acid, etc. do.

The metal ion sequestering agent may include disodium ethylenediaminetetraacetate, sodium ethylenediaminetetraacetate, etc., and the disinfectant may specifically include chlorhexidine gluconate, quaternary ammonium salt, pyroctonolamine, zinc pyrithione suspension, and iodopropynyl butyl. It can be carbamate, salicylic acid, etc.

The anti-inflammatory ingredients include monoammonium glycyrrhizinate, dipotassium glycyrrhizinate, allantoin, and mixtures thereof, and the antibacterial (antimicrobial) ingredients include phenoxyethanol, chlorhexidine, chlorhexidine gluconate, benzoic acid and its salts, and benzyl. Alcohol, salicylic acid, triclocarban, zinc pyrithione suspension, and mixtures thereof can be used.

The solubilizer may specifically include PEG 60-hydrogenated castor oil, and the flavoring agent may be a common ingredient used in the field of cosmetic compositions of the present invention.

However, the examples of the additional ingredients and other additives are not limited to the above, and are known to be commonly used in the field as long as they do not impair the properties and efficacy of the active ingredient and the second active ingredient. Any number of additional ingredients may be included, and a person skilled in the art may appropriately select and mix them depending on other formulations or purposes of use.

The content of each ingredient constituting the additional ingredients and other additives may be independently included within the range of 0.001 to 5% by weight based on the total weight of the cosmetic composition.

The cosmetic composition may contain purified water within the remaining amount.

The method of manufacturing the cosmetic composition may include the process of weighing and mixing all the components constituting the composition, heating them, and then stirring and mixing them with an ultra-high pressure disperser. At this time, each component may be added in order, and in some cases, may be added sequentially.

The heating may be performed at 50 to 80°C, preferably 60 to 80°C, and more preferably 75°C. At this time, if the temperature is less than 50℃, there may be a problem of phase separation of the cosmetic ingredients due to poor miscibility between compositions, and if the temperature exceeds 80℃, there may be problems with preservative power and/or formulation stability, so it should be kept within the above temperature range. After warming, it is desirable to carry out stirring and mixing with an ultra-high pressure disperser at this temperature.

Stirring and mixing using the ultra-high pressure disperser is performed at a pressure of 800 to 1,500 bar for 20 to 40 minutes, and preferably mixing is performed at a pressure of 800 to 1,200 bar for 20 to 40 minutes. At this time, the internal temperature of the ultra-high pressure disperser is 50 to 80 ℃, and the outlet temperature of the ultra-high pressure disperser is about 10 to 15 ℃.

However, it is not limited to this, and the method for producing the cosmetic composition may follow known techniques widely used in the field.

The cosmetic composition is, for example, soothing gel Oil-in-Water (O/W), Water-in-Oil (W/O), Water-inSilicone (silicone-in-water type) )(W/S), Oil-in-Water-in-Oil (O/W/O) or Water-in-Oil-in-Water (W/O/W) ) may be manufactured in a dosage form, but is not limited thereto.

The cosmetic composition includes, for example, solution, suspension, emulsion, paste, gel, essence, cream, lotion, ampoule, softening lotion, nourishing lotion, powder, soap, cleansing, oil, foundation, wax, pack, powder, compact. , can be made into lip gloss, lipstick, shadow, shampoo, conditioner or spray form products.

However, examples of application of the cosmetic composition are not limited thereto. In addition, it can be manufactured by applying known techniques to suit the desired final dosage form and product form.

The cosmetic composition may be used alone or in multiple applications, or may be used in multiple applications with other cosmetic compositions other than the present invention. Additionally, the cosmetic composition according to the present invention can be used according to conventional usage methods, and the number of uses can be varied depending on the user's skin condition or preference.

Hereinafter, the configuration of the present invention and its effects will be described in more detail through specific examples and comparative examples. However, these examples are for illustrating the present invention in more detail, and the scope of the present invention is not limited to these examples.

Examples and Comparative Examples

A cosmetic composition having a lotion formulation was prepared by applying the ingredient composition and content according to Table 1 below. The specific manufacturing method followed a known technique, and the concentration was adjusted using purified water and thickeners xanthan gum and carbomer, and other additives according to known ingredients to form a lotion formulation were included. Additionally, in order to ensure that all components were evenly dispersed, the mixture was heated to 75°C and stirred for 35 minutes at a pressure of 1,000 bar using an ultra-high pressure disperser (internal temperature 70°C). The content unit in Table 1 below is weight%.

<Experimental Example 1: Evaluation of skin cooling efficacy>

The skin cooling efficacy of each lotion prepared according to Examples 1 to 7 and Comparative Examples 1 to 3 was evaluated. The measurement method is as follows.

Targeting 50 adult women aged 19 to 49, they were divided into 10 groups with 5 people in each group. The skin temperature of the subjects' facial area was measured before applying the lotion, and then each lotion was applied. The temperature was measured immediately after and 30 minutes after the treatment, and the results were averaged and shown in Table 2 below.

As shown in Table 2, the Examples were confirmed to have an excellent skin cooling effect in reducing skin heat immediately after applying the lotion and even after 30 minutes. Among them, the results for skin cooling efficacy of Example 5 were evaluated as the best.

<Experimental Example 2: Evaluation of skin moisturizing efficacy>

The skin moisturizing effect of the lotions prepared according to Examples 1 to 7 and Comparative Examples 1 to 3 was measured. The measurement method is as follows.

50 women in their 20s to 40s without skin disease were divided into 10 groups, 5 people per group, and each group applied the lotion of Examples 1 to 7 and Comparative Examples 1 to 3 on their face twice daily for 1 month. It was applied to the entire surface. Before starting application, skin conductivity was measured using a corneometer (CM820 courage Khazaka electronic GmbH, Germany) under constant temperature and humidity conditions (24 degrees Celsius, 40% humidity), and the skin conductivity was taken as the default value, and the skin conductivity was measured after 1, 2, and 4 weeks. Conductivity was measured and the rate of increase was evaluated. The results are shown in Table 3 below.

As shown in Table 3, the skin conductivity increase rate of the Examples of the present invention was very excellent compared to the Comparative Examples. In general, skin conductivity is proportional to the amount of skin moisture, so it can be seen from the above results that cosmetics containing the ingredient composition of the present invention maintain a higher skin moisture content compared to cosmetics without the composition. That is, it was confirmed that the cosmetic composition according to an embodiment of the present invention had an excellent effect of improving skin moisturizing ability.

<Experimental Example 3: Sensory Evaluation>

The lotions prepared according to Examples 1 to 7 and Comparative Examples 1 to 3 were subjected to sensory evaluation for improvement in skin itching, skin elasticity, and skin vitality (or whitening).

50 women in their 20s to 40s without any special skin diseases were divided into 10 groups, 5 people per group, and each group applied the lotions of Examples 1 to 7 and Comparative Examples 1 to 3 twice daily for 2 months. It was applied to the entire face. After using each lotion, test subjects were asked to rate their subjective satisfaction with each item of skin itchiness improvement, skin elasticity, and skin vitality (or whitening) using a 5-point scale (1 point: very poor, 2 points: poor). , 3 points: average, 4 points: good, 5 points: very good). The results are shown in Table 4 below.

As shown in Table 4, it was confirmed that the Examples of the present invention showed superior effects in improving skin itching and increasing skin elasticity and skin vitality compared to the Comparative Examples. Among them, the sensory evaluation results for Example 5 were the most excellent.

In this specification, only a few examples of various embodiments performed by the present inventors are described, but the technical idea of the present invention is not limited or limited thereto, and of course, it can be modified and implemented in various ways by those skilled in the art.

Claims (9)

A cosmetic composition comprising Guaiazulene, Hyaluronic acid, Cyanocobalamin, and camellia oil as active ingredients. According to paragraph 1,
A cosmetic composition, characterized in that the active ingredient is contained in an amount of 0.1 to 8% by weight based on the total weight of the cosmetic composition. According to paragraph 1,
The mixing ratio of Guaiazulene, Hyaluronic acid, Cyanocobalamin, and camellia oil is a weight ratio of 1: 1 to 1.3: 0.8 to 1: 0.5 to 0.7. Characterized by a cosmetic composition. According to paragraph 1,
The cosmetic composition further comprises 0.01 to 3.5% by weight of a second active ingredient containing extracts of natural ingredients, based on the total weight. According to paragraph 4,
The second active ingredient is any one selected from the group consisting of Aerobiculus vulgaris extract, peony root extract, L. chinensis extract, niacinamide, pantothenic acid, allantoin, orange extract, biotin, panthenol, Centella asiatica extract, aloe extract, and combinations thereof. Characterized by a cosmetic composition. According to paragraph 1,
The cosmetic composition further comprises at least one moisturizing agent selected from sodium hyaluronate, glycerin, propylene glycol, 1,3-butylene glycol, dipropylene glycol, erythritol, and sorbitol. According to paragraph 1,
The cosmetic composition further comprises one or more thickeners selected from polyacrylate, xanthan gum, methylcellulose, hydroxyethylcellulose, carbomer, carrageenan, carboxymethylcellulose and hydroxymethylcellulose, Cosmetic composition. According to paragraph 1,
The cosmetic composition further comprises one or more pH adjusters selected from citric acid, sodium hydroxide, triethanolamine, sodium citrate, phosphoric acid, sodium phosphate, lactic acid, and tromethamine. According to paragraph 1,
The cosmetic composition includes solution, suspension, emulsion, paste, gel, essence, cream, lotion, ampoule, softening lotion, nourishing lotion, powder, soap, cleansing, oil, foundation, wax, pack, powder, pact, lip gloss. A cosmetic composition, characterized in that it is manufactured in the form of lipstick, shadow, shampoo, rinse or spray.