KR102552693B1 - 궤양성 결장염을 치료하는 방법 - Google Patents

궤양성 결장염을 치료하는 방법 Download PDF

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KR102552693B1
KR102552693B1 KR1020207027982A KR20207027982A KR102552693B1 KR 102552693 B1 KR102552693 B1 KR 102552693B1 KR 1020207027982 A KR1020207027982 A KR 1020207027982A KR 20207027982 A KR20207027982 A KR 20207027982A KR 102552693 B1 KR102552693 B1 KR 102552693B1
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KR20200128101A (ko
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제임스 베네딕트 캐너번
스튜어트 윌리엄 프리드리히
카트린 앤 크뤼거
캐서린 밀크
제이 로렌스 터틀
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일라이 릴리 앤드 캄파니
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020207027982A 2018-03-30 2019-03-28 궤양성 결장염을 치료하는 방법 Active KR102552693B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862650314P 2018-03-30 2018-03-30
US62/650,314 2018-03-30
PCT/US2019/024633 WO2019191464A1 (en) 2018-03-30 2019-03-28 Methods of treating ulcerative colitis

Publications (2)

Publication Number Publication Date
KR20200128101A KR20200128101A (ko) 2020-11-11
KR102552693B1 true KR102552693B1 (ko) 2023-07-07

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ID=66429483

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KR1020207027982A Active KR102552693B1 (ko) 2018-03-30 2019-03-28 궤양성 결장염을 치료하는 방법

Country Status (29)

Country Link
US (2) US12152072B2 (https=)
EP (2) EP4327866B1 (https=)
JP (4) JP7119114B2 (https=)
KR (1) KR102552693B1 (https=)
CN (1) CN111936165A (https=)
AU (2) AU2019243283C1 (https=)
BR (1) BR112020018099A2 (https=)
CA (1) CA3095297A1 (https=)
DK (2) DK3773715T3 (https=)
EA (1) EA202091989A1 (https=)
ES (2) ES3063700T3 (https=)
FI (2) FI4327866T3 (https=)
HR (2) HRP20260275T1 (https=)
HU (1) HUE067445T2 (https=)
IL (2) IL277514B2 (https=)
LT (2) LT3773715T (https=)
MA (2) MA52216B1 (https=)
MD (2) MD4327866T2 (https=)
MX (1) MX2020010269A (https=)
MY (1) MY202368A (https=)
PL (2) PL4327866T3 (https=)
PT (2) PT4327866T (https=)
RS (2) RS67806B1 (https=)
SG (1) SG11202009526RA (https=)
SI (2) SI3773715T1 (https=)
TW (2) TWI744617B (https=)
UA (1) UA128578C2 (https=)
WO (1) WO2019191464A1 (https=)
ZA (1) ZA202005388B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク，インコーポレーテツド Ｉｌ－２３及びｔｎｆアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
BR112022015996A2 (pt) * 2020-02-14 2022-10-11 Janssen Biotech Inc Método seguro e eficaz para tratar colite ulcerativa com anticorpo anti-il12/il23
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
JP7423815B2 (ja) * 2020-10-20 2024-01-29 セトラスホールディングス株式会社 治験管理装置、治験管理方法、治験管理プログラム及び治験管理システム
TW202241506A (zh) * 2021-01-06 2022-11-01 美商艾伯維有限公司 治療克羅恩氏病及潰瘍性結腸炎之方法
BR112023024064A2 (pt) * 2021-05-20 2024-01-30 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
JP2024521748A (ja) * 2021-05-28 2024-06-04 イーライ リリー アンド カンパニー 潰瘍性大腸炎に関与する遺伝子の抗ｉｌ－２３ｐ１９抗体調節
US20230159633A1 (en) * 2021-11-23 2023-05-25 Janssen Biotech, Inc. Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
AU2023383916A1 (en) * 2022-11-22 2025-07-10 Janssen Biotech, Inc. Method of treating ulcerative colitis with anti-il23 specific antibody
TW202500184A (zh) 2023-03-10 2025-01-01 美商美國禮來大藥廠 治療潰瘍性結腸炎之方法
CN121443635A (zh) * 2023-06-16 2026-01-30 信达生物医药科技(杭州)有限公司 重组抗白介素23p19亚基抗体在治疗炎症性肠病中的用途
WO2025170982A2 (en) 2024-02-06 2025-08-14 Paragon Therapeutics, Inc. Il-23 antibody compositions and methods of use
WO2026060205A1 (en) 2024-09-13 2026-03-19 Eli Lilly And Company PAN-ELR+ CXC CHEMOKINE ANTIBODIES AND IL-23p19 ANTIBODIES FOR THE TREATMENT OF ULCERATIVE COLITIS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120282269A1 (en) 2010-11-04 2012-11-08 Boehringer Ingelheim International Gmbh Anti-IL-23 Antibodies
US20170002060A1 (en) 2014-01-08 2017-01-05 Moderna Therapeutics, Inc. Polynucleotides for the in vivo production of antibodies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2452694T1 (sl) * 2005-06-30 2019-05-31 Janssen Biotech, Inc. Protitelesa proti-IL-23, sestavki in postopki uporabe
HUE034269T2 (en) 2005-12-29 2018-02-28 Janssen Biotech Inc Human anti-IL-23 antibodies, preparations, methods and applications
ES2708988T3 (es) 2007-02-23 2019-04-12 Merck Sharp & Dohme Anticuerpos anti-IL-23p19 obtenidos por ingeniería genética
JP2012507723A (ja) * 2008-11-03 2012-03-29 シェーリング コーポレイション 炎症性腸疾患生物マーカーおよび関連治療方法
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
AR094877A1 (es) 2013-03-08 2015-09-02 Lilly Co Eli Anticuerpos que se unen a il-23
MX2020009265A (es) * 2018-03-05 2020-10-01 Janssen Biotech Inc Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120282269A1 (en) 2010-11-04 2012-11-08 Boehringer Ingelheim International Gmbh Anti-IL-23 Antibodies
US20170002060A1 (en) 2014-01-08 2017-01-05 Moderna Therapeutics, Inc. Polynucleotides for the in vivo production of antibodies

Also Published As

Publication number Publication date
SI4327866T1 (sl) 2026-04-30
MA52216A (fr) 2021-02-17
MX2020010269A (es) 2020-11-06
RS67806B1 (sr) 2026-03-31
PT3773715T (pt) 2024-05-27
LT4327866T (lt) 2026-03-10
WO2019191464A1 (en) 2019-10-03
US12152072B2 (en) 2024-11-26
AU2023248103B2 (en) 2026-02-05
HRP20240904T1 (hr) 2024-10-11
ES2983809T3 (es) 2024-10-24
TWI744617B (zh) 2021-11-01
CA3095297A1 (en) 2019-10-03
HRP20260275T1 (hr) 2026-04-10
DK4327866T3 (da) 2026-02-23
ES3063700T3 (en) 2026-04-20
NZ767902A (en) 2024-05-31
IL277514B2 (en) 2024-11-01
MY202368A (en) 2024-04-24
JP2025020134A (ja) 2025-02-12
SI3773715T1 (sl) 2024-06-28
JP2022169562A (ja) 2022-11-09
ZA202005388B (en) 2025-05-28
MD3773715T2 (ro) 2024-10-31
EA202091989A1 (ru) 2021-01-13
US20250034243A1 (en) 2025-01-30
LT3773715T (lt) 2024-06-25
FI3773715T3 (fi) 2024-05-30
SG11202009526RA (en) 2020-10-29
MA52216B1 (fr) 2024-07-31
MD4327866T2 (ro) 2026-04-30
PL3773715T3 (pl) 2024-08-19
JP7331219B2 (ja) 2023-08-22
US20210032325A1 (en) 2021-02-04
AU2023248103A1 (en) 2023-11-09
BR112020018099A2 (pt) 2020-12-22
IL312807B1 (en) 2025-02-01
PL4327866T3 (pl) 2026-04-20
TW201946657A (zh) 2019-12-16
TW202206104A (zh) 2022-02-16
EP4327866A2 (en) 2024-02-28
EP4327866B1 (en) 2025-12-10
JP2023166388A (ja) 2023-11-21
JP2021517156A (ja) 2021-07-15
IL312807A (en) 2024-07-01
DK3773715T3 (da) 2024-05-27
MA67901B1 (fr) 2026-02-27
RS65661B1 (sr) 2024-07-31
IL277514B1 (en) 2024-07-01
UA128578C2 (uk) 2024-08-21
EP3773715A1 (en) 2021-02-17
AU2019243283B2 (en) 2023-07-27
PT4327866T (pt) 2026-02-17
HUE067445T2 (hu) 2024-10-28
AU2019243283A1 (en) 2020-09-24
JP7571225B2 (ja) 2024-10-22
IL312807B2 (en) 2025-06-01
FI4327866T3 (fi) 2026-02-18
JP7119114B2 (ja) 2022-08-16
IL277514A (en) 2020-11-30
TWI837532B (zh) 2024-04-01
EP3773715B1 (en) 2024-05-08
EP4327866A3 (en) 2024-03-20
CN111936165A (zh) 2020-11-13
KR20200128101A (ko) 2020-11-11
AU2019243283C1 (en) 2024-05-02

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